{"product_id":"agilent-1290-infinity-ii-elsd-g7102a-evaporative-light-scattering-detector","title":"Agilent 1290 Infinity II ELSD G7102A Evaporative Light Scattering Detector","description":"\u003ch2\u003eAgilent 1290 Infinity II ELSD G7102A Evaporative Light Scattering Detector – Used, Sold As-Is\u003c\/h2\u003e\n\u003cp\u003eThe Agilent 1290 Infinity II ELSD G7102A is an evaporative light scattering detector designed for liquid chromatography applications involving compounds that may be difficult or impossible to detect using conventional UV or fluorescence detection. By measuring light scattered from nonvolatile analyte particles after removal of the mobile phase, the 1290 Infinity II ELSD provides a versatile detection option for compounds without a useful UV chromophore or fluorophore.\u003c\/p\u003e\n\u003cp\u003eThe G7102A is well suited to HPLC and UHPLC applications involving lipids, carbohydrates, sugars, surfactants, polymers, pharmaceuticals, excipients, natural products, and other nonvolatile or semivolatile compounds. Its design combines controlled nebulization, solvent evaporation, a 405 nm laser, and dual photomultiplier tube detection with digital signal processing.\u003c\/p\u003e\n\u003cp\u003eThe detector supports liquid chromatography flow rates from 0.2 to 5.0 mL\/min and provides programmable gas flow from 0.9 to 3.25 SLM. High-speed digital output at 10, 40, or 80 Hz supports both conventional LC and faster chromatographic separations.\u003c\/p\u003e\n\u003cp\u003eThis Agilent 1290 Infinity II ELSD is offered used by American Instrument Exchange and is being sold as-is with no warranty. Customers should evaluate the unit accordingly and contact AIE with any questions regarding its condition, included accessories, or suitability for their intended LC configuration before purchase.\u003c\/p\u003e\n\u003ch3\u003eKey Features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eAgilent 1290 Infinity II Evaporative Light Scattering Detector\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eModel G7102A\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eDesigned for HPLC and UHPLC detection\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eDetects many compounds without a useful UV chromophore\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e405 nm, 10 mW laser light source\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eDual photomultiplier tubes with digital signal processing\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e0.2–5.0 mL\/min eluent flow range\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eProgrammable 0.9–3.25 SLM gas flow\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eControlled gas shut-off to reduce unnecessary gas consumption\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eNebulizer temperature settings from 25°C to 90°C or off\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eHigh-speed digital output at 10, 40, or 80 Hz\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eEthernet and RS-232 communication\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eCompatible with appropriate Agilent OpenLab software environments\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eCan be integrated into compatible third-party chromatography data environments\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eUsed equipment from American Instrument Exchange\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eSold as-is\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eNo warranty included\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eOverview\u003c\/h3\u003e\n\u003cp\u003eEvaporative light scattering detection provides an alternative to optical absorbance techniques such as UV and diode-array detection.\u003c\/p\u003e\n\u003cp\u003eA conventional UV detector requires the analyte to absorb light at an appropriate wavelength. Many important chemical compounds have weak or nonexistent UV chromophores, making direct UV detection difficult.\u003c\/p\u003e\n\u003cp\u003eELSD avoids this limitation by using a different detection principle.\u003c\/p\u003e\n\u003cp\u003eThe liquid chromatography eluent first enters a nebulizer, where it is converted into a fine aerosol. The mobile phase is then evaporated, leaving particles of less-volatile analytes behind. These particles pass through a laser beam and scatter light. The scattered light is measured by photomultiplier tubes and converted into a chromatographic signal.\u003c\/p\u003e\n\u003cp\u003eBecause detection is based on light scattering from residual analyte particles rather than their UV absorbance, ELSD can substantially expand the range of compounds detectable by an LC system.\u003c\/p\u003e\n\u003ch3\u003eKey Specifications\u003c\/h3\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecification\u003c\/th\u003e\n\u003cth\u003eDetails\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eManufacturer\u003c\/td\u003e\n\u003ctd\u003eAgilent Technologies\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eProduct Family\u003c\/td\u003e\n\u003ctd\u003e1290 Infinity II\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eModel\u003c\/td\u003e\n\u003ctd\u003eG7102A\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDetector Type\u003c\/td\u003e\n\u003ctd\u003eEvaporative Light Scattering Detector\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAbbreviation\u003c\/td\u003e\n\u003ctd\u003eELSD\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLight Source\u003c\/td\u003e\n\u003ctd\u003e405 nm, 10 mW Laser\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDetector\u003c\/td\u003e\n\u003ctd\u003eDual PMT with Digital Signal Processing\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eEluent Flow Range\u003c\/td\u003e\n\u003ctd\u003e0.2–5.0 mL\/min\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGas Flow Range\u003c\/td\u003e\n\u003ctd\u003e0.9–3.25 SLM\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRequired Gas Pressure\u003c\/td\u003e\n\u003ctd\u003e60–100 psi \/ 4.1–6.9 bar\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNebulizer Temperature\u003c\/td\u003e\n\u003ctd\u003eOff or 25–90°C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNon-Cooled Evaporator Range\u003c\/td\u003e\n\u003ctd\u003eOff or 25–120°C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCooled Evaporator Range\u003c\/td\u003e\n\u003ctd\u003eOff or 10–80°C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDigital Output\u003c\/td\u003e\n\u003ctd\u003e10, 40, or 80 Hz, 24-bit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCommunication\u003c\/td\u003e\n\u003ctd\u003eEthernet \/ RS-232\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRemote Operation\u003c\/td\u003e\n\u003ctd\u003eRemote Start Input\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSafety Features\u003c\/td\u003e\n\u003ctd\u003eGas Shut-Off Valve, Leak Detection, Laser Interlock\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDimensions\u003c\/td\u003e\n\u003ctd\u003eApprox. 16.3\"H × 7.9\"W × 17.7\"D\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight\u003c\/td\u003e\n\u003ctd\u003eApprox. 11 kg Non-Cooled \/ 13 kg Cooled\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eElectrical\u003c\/td\u003e\n\u003ctd\u003e100–240 V, 50\/60 Hz\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMaximum Power Consumption\u003c\/td\u003e\n\u003ctd\u003e150 W\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCondition\u003c\/td\u003e\n\u003ctd\u003eUsed\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSale Condition\u003c\/td\u003e\n\u003ctd\u003eSold As-Is\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWarranty\u003c\/td\u003e\n\u003ctd\u003eNone\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3\u003eCommon Applications\u003c\/h3\u003e\n\u003cp\u003eThe Agilent 1290 Infinity II ELSD can be used for liquid chromatography applications involving analytes that do not respond strongly to conventional UV or fluorescence detectors.\u003c\/p\u003e\n\u003cp\u003eTypical applications include analysis of lipids, carbohydrates, sugars, surfactants, polymers, pharmaceutical compounds, excipients, natural products, food components, synthetic compounds, and other nonvolatile or semivolatile analytes compatible with evaporative light scattering detection.\u003c\/p\u003e\n\u003cp\u003eThe detector can also be valuable in methods where samples contain multiple compounds with substantially different UV absorbance characteristics.\u003c\/p\u003e\n\u003ch3\u003eIdeal Laboratory Types\u003c\/h3\u003e\n\u003cp\u003eThe G7102A is well suited to pharmaceutical development laboratories, biotechnology companies, analytical chemistry laboratories, university research facilities, contract research organizations, food and beverage laboratories, chemical manufacturers, polymer laboratories, natural-products laboratories, formulation-development groups, and other organizations using HPLC or UHPLC.\u003c\/p\u003e\n\u003cp\u003eIt may be particularly useful for laboratories that already operate Agilent Infinity-series LC equipment and need to add evaporative light scattering detection to an existing chromatographic workflow.\u003c\/p\u003e\n\u003ch3\u003eHow Evaporative Light Scattering Detection Works\u003c\/h3\u003e\n\u003cp\u003eELSD analysis can be understood as a three-stage process: nebulization, evaporation, and optical detection.\u003c\/p\u003e\n\u003cp\u003eFirst, LC column effluent enters the nebulizer and is transformed into a fine aerosol using gas.\u003c\/p\u003e\n\u003cp\u003eThe aerosol then enters the evaporation region. The volatile mobile phase is removed, leaving less-volatile analyte particles behind.\u003c\/p\u003e\n\u003cp\u003eFinally, the remaining particles pass through the detector's laser beam. Light scattered by those particles is measured by photomultiplier tubes and converted into the ELSD response.\u003c\/p\u003e\n\u003cp\u003eThis detection mechanism does not depend on the analyte having a strong UV chromophore.\u003c\/p\u003e\n\u003ch3\u003eDetecting Compounds with Little or No UV Absorbance\u003c\/h3\u003e\n\u003cp\u003eOne of the primary reasons laboratories add an ELSD to an HPLC or UHPLC system is to detect compounds that are difficult to measure with UV absorbance.\u003c\/p\u003e\n\u003cp\u003eA UV detector relies on the molecular structure of the analyte to absorb light at the selected wavelength. Compounds without an appropriate chromophore may generate little or no useful UV response.\u003c\/p\u003e\n\u003cp\u003eAn ELSD instead responds to less-volatile analyte particles remaining after the mobile phase has been evaporated.\u003c\/p\u003e\n\u003cp\u003eThis makes the G7102A useful as an additional detector for applications where UV detection alone does not provide adequate analytical coverage.\u003c\/p\u003e\n\u003ch3\u003e405 nm Laser and Dual-PMT Detection\u003c\/h3\u003e\n\u003cp\u003eThe Agilent 1290 Infinity II ELSD uses a 405 nm, 10 mW laser as its light source.\u003c\/p\u003e\n\u003cp\u003eAfter the mobile phase has been removed, residual analyte particles pass through the laser beam and scatter light.\u003c\/p\u003e\n\u003cp\u003eThe detector uses dual photomultiplier tubes combined with digital signal processing to measure this scattered light and generate the chromatographic signal.\u003c\/p\u003e\n\u003cp\u003eThis optical arrangement is specifically designed for evaporative light scattering detection rather than conventional absorbance measurement.\u003c\/p\u003e\n\u003ch3\u003e0.2 to 5.0 mL\/min Eluent Flow Range\u003c\/h3\u003e\n\u003cp\u003eThe G7102A supports LC eluent flow rates from approximately 0.2 to 5.0 mL\/min.\u003c\/p\u003e\n\u003cp\u003eThis broad range allows the detector to be used across a variety of HPLC and UHPLC methods.\u003c\/p\u003e\n\u003cp\u003eActual operating conditions must be optimized according to column dimensions, mobile phase, solvent composition, nebulizer settings, evaporation conditions, gas flow, analyte characteristics, and the requirements of the analytical method.\u003c\/p\u003e\n\u003ch3\u003eProgrammable Gas Flow\u003c\/h3\u003e\n\u003cp\u003eThe 1290 Infinity II ELSD provides gas-flow control from approximately 0.9 to 3.25 standard liters per minute.\u003c\/p\u003e\n\u003cp\u003eGas plays an important role in nebulization and solvent evaporation.\u003c\/p\u003e\n\u003cp\u003eAgilent also incorporates a controlled gas shut-off valve into the detector. When the system is no longer actively running, gas consumption can be reduced and ultimately shut off rather than continuing indefinitely at the normal operating flow.\u003c\/p\u003e\n\u003cp\u003eThis can help reduce unnecessary consumption of the detector gas supply.\u003c\/p\u003e\n\u003ch3\u003eNebulizer Temperature Control\u003c\/h3\u003e\n\u003cp\u003eThe G7102A provides nebulizer temperature settings from approximately 25°C to 90°C, with the ability to turn nebulizer heating off.\u003c\/p\u003e\n\u003cp\u003eNebulization conditions affect aerosol formation and can influence ELSD response.\u003c\/p\u003e\n\u003cp\u003eThe appropriate setting depends on mobile-phase composition, flow rate, analyte properties, evaporation conditions, and the specific analytical method.\u003c\/p\u003e\n\u003cp\u003eELSD methods therefore require optimization rather than simply operating every sample under the same temperature and gas settings.\u003c\/p\u003e\n\u003ch3\u003eLow-Temperature Evaporation Capability\u003c\/h3\u003e\n\u003cp\u003eA particularly useful characteristic of Agilent's ELSD design is its ability to support relatively low evaporation temperatures.\u003c\/p\u003e\n\u003cp\u003eTraditional ELSD methods can require substantial heat to remove aqueous or otherwise difficult mobile phases. Excessive evaporator temperature can reduce the response of semivolatile or thermally sensitive compounds because part of the analyte may evaporate along with the mobile phase.\u003c\/p\u003e\n\u003cp\u003eThe 1290 Infinity II ELSD was designed to improve solvent evaporation at lower temperatures, expanding its usefulness for compounds that may be poorly suited to high-temperature ELSD conditions.\u003c\/p\u003e\n\u003ch3\u003eCooled and Non-Cooled Configurations\u003c\/h3\u003e\n\u003cp\u003eAgilent offered the G7102A platform in cooled and non-cooled evaporator configurations.\u003c\/p\u003e\n\u003cp\u003eThe non-cooled evaporator operates from approximately 25°C to 120°C or can be switched off.\u003c\/p\u003e\n\u003cp\u003eThe cooled configuration extends the lower operating range to approximately 10°C, with an upper evaporator temperature of approximately 80°C.\u003c\/p\u003e\n\u003cp\u003eThe exact configuration of this individual used detector should be confirmed before purchase if subambient evaporator operation is required for the intended method.\u003c\/p\u003e\n\u003ch3\u003eHigh-Speed Data Acquisition\u003c\/h3\u003e\n\u003cp\u003eThe 1290 Infinity II ELSD provides digital output at 10, 40, or 80 Hz with 24-bit data handling.\u003c\/p\u003e\n\u003cp\u003eFast data acquisition is valuable when chromatographic peaks become narrow, as can occur in high-efficiency and fast-LC separations.\u003c\/p\u003e\n\u003cp\u003eA sufficiently high detector sampling rate helps define these narrow peaks accurately rather than recording too few data points across each chromatographic event.\u003c\/p\u003e\n\u003cp\u003eThis makes the G7102A suitable for integration into appropriately configured high-performance LC workflows.\u003c\/p\u003e\n\u003ch3\u003eHPLC and UHPLC Applications\u003c\/h3\u003e\n\u003cp\u003eAlthough the detector carries the 1290 Infinity II name, ELSD detection is not limited exclusively to one particular Agilent LC stack.\u003c\/p\u003e\n\u003cp\u003eThe detector's broad eluent flow range, digital communication capabilities, and chromatography-software support allow it to function within a variety of appropriately configured LC environments.\u003c\/p\u003e\n\u003cp\u003eCompatibility should always be verified for the intended pumps, autosamplers, chromatography data system, communications architecture, and analytical method before purchasing a used detector.\u003c\/p\u003e\n\u003ch3\u003eAgilent OpenLab Compatibility\u003c\/h3\u003e\n\u003cp\u003eThe G7102A can be controlled using compatible Agilent chromatography software and ELSD drivers.\u003c\/p\u003e\n\u003cp\u003eAgilent documentation identifies support for OpenLab ChemStation and OpenLab EZChrom environments when the appropriate software versions and detector drivers are installed.\u003c\/p\u003e\n\u003cp\u003eSoftware compatibility can depend on the operating system, CDS revision, instrument driver, firmware, and other system components.\u003c\/p\u003e\n\u003cp\u003eSoftware licenses are not implied to be included with this used detector unless specifically stated in the sales listing.\u003c\/p\u003e\n\u003ch3\u003eWaters Empower Integration\u003c\/h3\u003e\n\u003cp\u003eThe Agilent 1290 Infinity II ELSD can also be integrated into appropriately configured Waters Empower environments.\u003c\/p\u003e\n\u003cp\u003eAgilent documentation describes configuration of the detector in Empower using supported Agilent Instrument Control Framework components, with communication established through LAN or RS-232.\u003c\/p\u003e\n\u003cp\u003eThis can make the G7102A useful to laboratories operating mixed-manufacturer chromatography environments.\u003c\/p\u003e\n\u003cp\u003eSoftware, driver, firmware, and communication compatibility should be verified for the laboratory's specific Empower installation before purchase.\u003c\/p\u003e\n\u003ch3\u003eEthernet and RS-232 Communication\u003c\/h3\u003e\n\u003cp\u003eThe G7102A provides both Ethernet and serial RS-232 communication.\u003c\/p\u003e\n\u003cp\u003eThese options provide flexibility when integrating the detector with compatible chromatography workstations and data systems.\u003c\/p\u003e\n\u003cp\u003eThe appropriate communication method depends on the software environment and overall LC configuration.\u003c\/p\u003e\n\u003cp\u003eCustomers replacing an existing ELSD should verify communication requirements and driver compatibility before installing a replacement detector.\u003c\/p\u003e\n\u003ch3\u003eApplications in Pharmaceutical Analysis\u003c\/h3\u003e\n\u003cp\u003eEvaporative light scattering detection can be particularly useful in pharmaceutical development and analytical laboratories because many compounds relevant to formulation work do not provide strong UV response.\u003c\/p\u003e\n\u003cp\u003ePotential applications include analysis of active compounds, formulation components, excipients, surfactants, lipids, sugars, and other substances suitable for ELSD analysis.\u003c\/p\u003e\n\u003cp\u003eELSD may be used independently or alongside other detectors to provide complementary information about a chromatographic separation.\u003c\/p\u003e\n\u003ch3\u003eCarbohydrate and Sugar Analysis\u003c\/h3\u003e\n\u003cp\u003eMany carbohydrates and sugars lack strong UV chromophores, making them challenging targets for conventional UV detection.\u003c\/p\u003e\n\u003cp\u003eELSD provides an alternative detection mechanism because response does not depend on UV absorbance.\u003c\/p\u003e\n\u003cp\u003eWhen the compounds are sufficiently less volatile than the mobile phase and the chromatographic method is compatible with ELSD, the detector can provide useful detection for carbohydrate-related applications.\u003c\/p\u003e\n\u003ch3\u003eLipid Analysis\u003c\/h3\u003e\n\u003cp\u003eLipids are another important class of compounds commonly associated with evaporative light scattering detection.\u003c\/p\u003e\n\u003cp\u003eDepending on the chromatography and analyte characteristics, ELSD can provide detection for lipid species that are difficult to monitor effectively with conventional UV methods.\u003c\/p\u003e\n\u003cp\u003eApplications may include pharmaceutical, biotechnology, food-science, natural-products, and biochemical research.\u003c\/p\u003e\n\u003ch3\u003ePolymer and Surfactant Analysis\u003c\/h3\u003e\n\u003cp\u003ePolymers and surfactants can also present challenges for conventional optical detection.\u003c\/p\u003e\n\u003cp\u003eWhen analytes are sufficiently nonvolatile for ELSD, the G7102A can provide an alternative means of detecting separated compounds after mobile-phase evaporation.\u003c\/p\u003e\n\u003cp\u003eThis can make the detector useful in chemical development, formulation, materials research, and quality-control environments.\u003c\/p\u003e\n\u003ch3\u003eELSD vs. UV Detection\u003c\/h3\u003e\n\u003cp\u003eELSD and UV detectors operate according to fundamentally different principles.\u003c\/p\u003e\n\u003cp\u003eUV detectors measure absorption of light by compounds containing suitable chromophores. They can provide excellent sensitivity and linearity for compatible analytes but may provide weak response for compounds lacking UV-active functional groups.\u003c\/p\u003e\n\u003cp\u003eELSD does not require a UV chromophore. Instead, it detects light scattered by residual analyte particles after mobile-phase evaporation.\u003c\/p\u003e\n\u003cp\u003eFor some laboratories, the two technologies are complementary rather than direct substitutes.\u003c\/p\u003e\n\u003ch3\u003eELSD vs. Refractive Index Detection\u003c\/h3\u003e\n\u003cp\u003eRefractive index detectors can also provide relatively universal detection for compounds lacking UV chromophores.\u003c\/p\u003e\n\u003cp\u003eHowever, ELSD and refractive index detection have different operating characteristics and method requirements.\u003c\/p\u003e\n\u003cp\u003eELSD removes the mobile phase before detection and can be used with appropriately developed gradient methods. Refractive index detection is generally much more sensitive to changes in mobile-phase composition and is therefore commonly associated with isocratic methods.\u003c\/p\u003e\n\u003cp\u003eThe appropriate detector depends on the analytes, mobile phase, chromatographic method, sensitivity requirements, and laboratory workflow.\u003c\/p\u003e\n\u003ch3\u003eELSD vs. Mass Spectrometry\u003c\/h3\u003e\n\u003cp\u003eELSD and mass spectrometry can both detect compounds that may be difficult to analyze using UV detection, but they serve very different analytical needs.\u003c\/p\u003e\n\u003cp\u003eMass spectrometry can provide molecular-mass and structural information in addition to detection, while ELSD provides a comparatively straightforward chromatographic response based on light scattering.\u003c\/p\u003e\n\u003cp\u003eFor laboratories that need routine detection rather than compound identification or structural characterization, ELSD may provide an appropriate alternative or complementary detector.\u003c\/p\u003e\n\u003ch3\u003eGas Supply Requirements\u003c\/h3\u003e\n\u003cp\u003eThe G7102A requires an appropriate gas supply for nebulization and evaporation.\u003c\/p\u003e\n\u003cp\u003eAgilent specifies an operating gas pressure of approximately 60 to 100 psi, or 4.1 to 6.9 bar, with instrument-controlled gas flow from 0.9 to 3.25 SLM.\u003c\/p\u003e\n\u003cp\u003eLaboratories should confirm the appropriate gas quality, regulator, tubing, exhaust routing, and facility connections before installation.\u003c\/p\u003e\n\u003cp\u003eProper exhaust handling is also important because the detector removes and exhausts mobile-phase solvent during operation.\u003c\/p\u003e\n\u003ch3\u003eSafety and Monitoring Features\u003c\/h3\u003e\n\u003cp\u003eAgilent incorporates several protective features into the 1290 Infinity II ELSD.\u003c\/p\u003e\n\u003cp\u003eThese include a controlled gas shut-off valve, leak detection, and laser interlock.\u003c\/p\u003e\n\u003cp\u003eThe ELSD contains a laser system and should be operated with its protective covers and safety interlocks intact.\u003c\/p\u003e\n\u003cp\u003eUsers should follow Agilent operating instructions and established laboratory procedures when installing, servicing, or operating the detector.\u003c\/p\u003e\n\u003ch3\u003eInstallation Considerations\u003c\/h3\u003e\n\u003cp\u003eBefore installing a used G7102A, laboratories should verify available bench space, electrical service, gas supply, exhaust requirements, LC tubing connections, network or serial communication, software compatibility, firmware requirements, and the physical configuration of the detector.\u003c\/p\u003e\n\u003cp\u003eThe module measures approximately 16.3 inches high × 7.9 inches wide × 17.7 inches deep.\u003c\/p\u003e\n\u003cp\u003eAgilent specifies a weight of approximately 11 kg for the non-cooled configuration and approximately 13 kg for the cooled configuration.\u003c\/p\u003e\n\u003ch3\u003eUsed Agilent 1290 Infinity II ELSD from American Instrument Exchange\u003c\/h3\u003e\n\u003cp\u003eThis Agilent 1290 Infinity II ELSD is being offered by American Instrument Exchange as used equipment.\u003c\/p\u003e\n\u003cp\u003eUnlike AIE equipment sold as refurbished and backed by a standard warranty, this particular detector is being sold as-is.\u003c\/p\u003e\n\u003cp\u003eCustomers should not assume that the detector has received the same level of refurbishment, operational verification, calibration, or performance testing associated with AIE's refurbished equipment unless a specific service is separately documented.\u003c\/p\u003e\n\u003ch3\u003eSold As-Is – No Warranty\u003c\/h3\u003e\n\u003cp\u003eThis Agilent G7102A is sold as-is with no warranty.\u003c\/p\u003e\n\u003cp\u003eThe buyer should evaluate the equipment with this condition in mind and should confirm any questions regarding physical condition, included accessories, configuration, and known operational status with American Instrument Exchange before purchasing.\u003c\/p\u003e\n\u003cp\u003eNo warranty is expressed or implied as part of the sale of this unit.\u003c\/p\u003e\n\u003ch3\u003eIncluded Components and Accessories\u003c\/h3\u003e\n\u003cp\u003eOnly components specifically identified by American Instrument Exchange as included with the individual unit should be assumed to accompany the detector.\u003c\/p\u003e\n\u003cp\u003eAn ELSD installation may require gas tubing and regulation, exhaust connections, solvent waste arrangements, LC capillaries or tubing, communication cables, compatible software and drivers, and other system-specific components.\u003c\/p\u003e\n\u003cp\u003eCustomers integrating the G7102A into an existing LC system should verify these requirements before purchase.\u003c\/p\u003e\n\u003ch3\u003eRelated Equipment\u003c\/h3\u003e\n\u003cp\u003eLaboratories using the Agilent 1290 Infinity II ELSD may also require compatible HPLC or UHPLC pumps, autosamplers, column compartments, chromatography columns, solvent-management equipment, nitrogen or other specified gas supplies, computers, and chromatography data systems.\u003c\/p\u003e\n\u003cp\u003eAmerican Instrument Exchange also supplies used and refurbished HPLC systems, analytical instruments, balances, centrifuges, vacuum equipment, and other laboratory equipment for pharmaceutical, biotechnology, chemical, and research applications.\u003c\/p\u003e\n\u003ch3\u003eAgilent 1290 Infinity II ELSD G7102A FAQs\u003c\/h3\u003e\n\u003ch4\u003eWhat is the Agilent 1290 Infinity II ELSD?\u003c\/h4\u003e\n\u003cp\u003eThe G7102A is an evaporative light scattering detector designed for liquid chromatography analysis of suitable nonvolatile and semivolatile compounds.\u003c\/p\u003e\n\u003ch4\u003eWhat does ELSD stand for?\u003c\/h4\u003e\n\u003cp\u003eELSD stands for Evaporative Light Scattering Detector.\u003c\/p\u003e\n\u003ch4\u003eWhat is an ELSD used for?\u003c\/h4\u003e\n\u003cp\u003eELSD is commonly used to detect compounds that are difficult to analyze with UV or fluorescence detectors because they lack a useful chromophore or fluorophore.\u003c\/p\u003e\n\u003ch4\u003eHow does the Agilent G7102A detect compounds?\u003c\/h4\u003e\n\u003cp\u003eThe detector nebulizes LC effluent, evaporates the mobile phase, passes the remaining analyte particles through a laser beam, and measures the resulting scattered light.\u003c\/p\u003e\n\u003ch4\u003eWhat type of light source does it use?\u003c\/h4\u003e\n\u003cp\u003eThe G7102A uses a 405 nm, 10 mW laser.\u003c\/p\u003e\n\u003ch4\u003eWhat type of detector does it use?\u003c\/h4\u003e\n\u003cp\u003eIt uses dual photomultiplier tubes with digital signal processing.\u003c\/p\u003e\n\u003ch4\u003eWhat LC flow rates can the G7102A handle?\u003c\/h4\u003e\n\u003cp\u003eAgilent specifies an eluent flow range from approximately 0.2 to 5.0 mL\/min.\u003c\/p\u003e\n\u003ch4\u003eWhat is the gas-flow range?\u003c\/h4\u003e\n\u003cp\u003eThe specified gas-flow range is approximately 0.9 to 3.25 SLM.\u003c\/p\u003e\n\u003ch4\u003eWhat gas pressure is required?\u003c\/h4\u003e\n\u003cp\u003eAgilent specifies an operating pressure of approximately 60 to 100 psi, or 4.1 to 6.9 bar.\u003c\/p\u003e\n\u003ch4\u003eWhat is the nebulizer temperature range?\u003c\/h4\u003e\n\u003cp\u003eThe nebulizer can be switched off or operated from approximately 25°C to 90°C.\u003c\/p\u003e\n\u003ch4\u003eCan the G7102A operate at low evaporator temperatures?\u003c\/h4\u003e\n\u003cp\u003eCooled configurations can operate the evaporator down to approximately 10°C. The exact configuration of this individual unit should be confirmed if subambient operation is required.\u003c\/p\u003e\n\u003ch4\u003eCan ELSD detect compounds that do not absorb UV light?\u003c\/h4\u003e\n\u003cp\u003eYes. This is one of the principal advantages of ELSD. Detection is based on light scattering rather than UV absorbance.\u003c\/p\u003e\n\u003ch4\u003eCan it be used for carbohydrates?\u003c\/h4\u003e\n\u003cp\u003eYes, ELSD is commonly used for suitable carbohydrates and sugars that may lack strong UV chromophores.\u003c\/p\u003e\n\u003ch4\u003eCan it be used for lipids?\u003c\/h4\u003e\n\u003cp\u003eYes. Lipid analysis is a common application for evaporative light scattering detection when the compounds and chromatographic method are appropriate.\u003c\/p\u003e\n\u003ch4\u003eCan it be used for polymers or surfactants?\u003c\/h4\u003e\n\u003cp\u003eYes. Suitable nonvolatile polymers, surfactants, and related compounds may be analyzed by ELSD.\u003c\/p\u003e\n\u003ch4\u003eDoes ELSD work with every compound?\u003c\/h4\u003e\n\u003cp\u003eNo. The analyte generally must remain less volatile than the mobile phase under the selected ELSD conditions. Method suitability should be established for the compounds being analyzed.\u003c\/p\u003e\n\u003ch4\u003eCan the G7102A be used with gradient chromatography?\u003c\/h4\u003e\n\u003cp\u003eYes. ELSD can be used with appropriately developed gradient LC methods.\u003c\/p\u003e\n\u003ch4\u003eIs the detector compatible with Agilent OpenLab?\u003c\/h4\u003e\n\u003cp\u003eAgilent provides ELSD drivers for compatible OpenLab environments. Exact software and driver compatibility should be verified for the laboratory's installation.\u003c\/p\u003e\n\u003ch4\u003eCan it be integrated with Waters Empower?\u003c\/h4\u003e\n\u003cp\u003eThe G7102A can be integrated into appropriately configured Empower environments using supported Agilent ICF components and communication methods.\u003c\/p\u003e\n\u003ch4\u003eWhat data rates are available?\u003c\/h4\u003e\n\u003cp\u003eThe detector provides 10, 40, or 80 Hz digital output.\u003c\/p\u003e\n\u003ch4\u003eIs software included with this detector?\u003c\/h4\u003e\n\u003cp\u003eSoftware should not be assumed to be included unless specifically stated by American Instrument Exchange.\u003c\/p\u003e\n\u003ch4\u003eIs this Agilent 1290 Infinity II ELSD refurbished?\u003c\/h4\u003e\n\u003cp\u003eNo. This particular detector is being offered as used equipment and sold as-is.\u003c\/p\u003e\n\u003ch4\u003eDoes this G7102A include a warranty?\u003c\/h4\u003e\n\u003cp\u003eNo. This unit is sold as-is with no warranty.\u003c\/p\u003e\n\u003ch4\u003eShould buyers verify the exact configuration before purchase?\u003c\/h4\u003e\n\u003cp\u003eYes. Buyers should confirm the detector configuration, condition, included accessories, software requirements, and compatibility with their existing LC system before purchase.\u003c\/p\u003e","brand":"Agilent","offers":[{"title":"Default Title","offer_id":50463892734000,"sku":"2987D HPLC","price":4500.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0252\/1228\/9072\/files\/DSC_0007b.jpg?v=1790020123","url":"https:\/\/www.americaninstrument.com\/products\/agilent-1290-infinity-ii-elsd-g7102a-evaporative-light-scattering-detector","provider":"American Instrument Exchange","version":"1.0","type":"link"}