{"product_id":"sakura-tissue-tek-autosection-5010-automated-microtome","title":"Sakura Tissue-Tek AutoSection 5010 Automated Microtome","description":"\u003ch2\u003eSakura Tissue-Tek AutoSection 5010 Automated Microtome\u003c\/h2\u003e\n\u003cp\u003eThe \u003cstrong\u003eSakura Tissue-Tek AutoSection 5010 Automated Microtome\u003c\/strong\u003e is a fully automated histology microtome designed to improve the consistency, efficiency, ergonomics, and reproducibility of paraffin sectioning in clinical pathology and research laboratories. Combining automated block-to-blade alignment, one-touch block facing, programmable sectioning, a precision 3D specimen holder, touchscreen controls, and wireless remote operation, the AutoSection 5010 reduces many of the manual steps traditionally required during routine microtomy.\u003c\/p\u003e\n\u003cp\u003eUnlike conventional rotary microtomes that depend heavily on operator technique for block orientation, trimming, and handwheel operation, the Tissue-Tek AutoSection uses Sakura's \u003cstrong\u003eAutoAlign, AutoTrim, and AutoSection technologies\u003c\/strong\u003e to automate critical stages of the sectioning process. The instrument senses the relationship between the paraffin block and blade, automatically adjusts specimen orientation, faces the block, and produces sections according to stored protocols.\u003c\/p\u003e\n\u003cp\u003eThis combination can help laboratories achieve more standardized results between operators while also reducing unnecessary loss of valuable tissue during block alignment and facing.\u003c\/p\u003e\n\u003cp\u003eThe Tissue-Tek AutoSection 5010 accommodates most commonly used histology cassettes and is optimized for use with Sakura's sectionable cassette system. A broad \u003cstrong\u003e0.5 to 100 micron section-thickness range\u003c\/strong\u003e, programmable speeds up to \u003cstrong\u003e450 mm\/second\u003c\/strong\u003e, and up to \u003cstrong\u003e15 presets with as many as 16 protocol steps\u003c\/strong\u003e give laboratories considerable flexibility for routine diagnostic histology, research sectioning, special procedures, and different tissue types.\u003c\/p\u003e\n\u003cp\u003eThis \u003cstrong\u003eused and refurbished Sakura Tissue-Tek AutoSection 5010\u003c\/strong\u003e from American Instrument Exchange is inspected, cleaned, and functionally tested prior to shipment, providing pathology and histology laboratories with access to a sophisticated automated microtomy platform at substantially lower cost than purchasing comparable equipment new.\u003c\/p\u003e\n\u003ch3\u003eKey Features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eFully automated paraffin microtome\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eSakura model \u003cstrong\u003e5010\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eAutomated block-to-blade alignment\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eAutoAlign block orientation technology\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eOne-touch AutoTrim block facing\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eAutomated programmable sectioning\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003ePrecision motorized \u003cstrong\u003e3D specimen holder\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eVertical and horizontal specimen orientation of \u003cstrong\u003e±4 degrees\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eOrientation resolution of \u003cstrong\u003e0.05 degree\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eBlock-to-blade alignment accuracy of approximately \u003cstrong\u003e±0.05 degree\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eSection thickness range of \u003cstrong\u003e0.5–100 µm\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eTrimming thickness range of \u003cstrong\u003e1–200 µm\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eSectioning, trimming, and return speeds of \u003cstrong\u003e10–450 mm\/sec\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eUp to \u003cstrong\u003e15 sectioning presets\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eUp to \u003cstrong\u003e16 steps per protocol\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eUp to \u003cstrong\u003e32 user preferences\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eAdjustable specimen retraction\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e4.3-inch color LCD touchscreen\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eBluetooth wireless handheld remote\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eUSB 2.0 data interface\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003ePassword-protected administrator access\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eCompatible with common paraffin tissue cassettes\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eSupports high- and low-profile disposable microtome blades\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eAutomated operation reduces repetitive handwheel motion\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eDesigned for routine and research histopathology\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eUsed and refurbished by American Instrument Exchange\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eOverview\u003c\/h3\u003e\n\u003cp\u003eMicrotomy is one of the most technique-dependent stages of the histology workflow.\u003c\/p\u003e\n\u003cp\u003eEven experienced histotechnologists must repeatedly manage several variables:\u003c\/p\u003e\n\u003cp\u003eBlock orientation\u003cbr\u003eBlade position\u003cbr\u003eFacing depth\u003cbr\u003eSection thickness\u003cbr\u003eCutting speed\u003cbr\u003eSpecimen feed\u003cbr\u003eRibbon formation\u003cbr\u003eTissue preservation\u003c\/p\u003e\n\u003cp\u003eSmall differences in these variables can affect section quality and can contribute to variation between operators.\u003c\/p\u003e\n\u003cp\u003eThe Sakura Tissue-Tek AutoSection 5010 was developed to automate several of these processes.\u003c\/p\u003e\n\u003cp\u003eRather than functioning simply as a motor-driven version of a conventional rotary microtome, the AutoSection combines sensors, programmable motion, and a motorized three-dimensional specimen holder to create a more standardized approach to paraffin sectioning.\u003c\/p\u003e\n\u003ch3\u003eKey Specifications\u003c\/h3\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecification\u003c\/th\u003e\n\u003cth\u003eDetails\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eManufacturer\u003c\/td\u003e\n\u003ctd\u003eSakura Finetek\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eProduct Line\u003c\/td\u003e\n\u003ctd\u003eTissue-Tek AutoSection\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eModel \/ Product Code\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e5010\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eEquipment Type\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003eFully Automated Microtome\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePrimary Application\u003c\/td\u003e\n\u003ctd\u003eParaffin-embedded tissue sectioning\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSection Thickness Range\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e0.5–100 µm\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTrimming Thickness Range\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e1–200 µm\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSectioning Speed\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e10–450 mm\/sec\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTrimming Speed\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e10–450 mm\/sec\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eReturn Speed\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e10–450 mm\/sec\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRetraction\u003c\/td\u003e\n\u003ctd\u003eNo retraction or \u003cstrong\u003e20–100 µm\u003c\/strong\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTypical Vertical Stroke\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e132 mm \/ 5.2 in.\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTypical Horizontal Stroke\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e9.4 mm \/ 0.37 in.\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSectioning Presets\u003c\/td\u003e\n\u003ctd\u003eUp to \u003cstrong\u003e15\u003c\/strong\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eProtocol Steps\u003c\/td\u003e\n\u003ctd\u003eUp to \u003cstrong\u003e16\u003c\/strong\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eUser Preferences\u003c\/td\u003e\n\u003ctd\u003eUp to \u003cstrong\u003e32\u003c\/strong\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSpecimen Orientation\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e±4° vertical and horizontal\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOrientation Resolution\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e0.05°\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBlade Alignment Accuracy\u003c\/td\u003e\n\u003ctd\u003eApprox. \u003cstrong\u003e±0.05°\u003c\/strong\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBlock-to-Blade Distance Accuracy\u003c\/td\u003e\n\u003ctd\u003eApprox. \u003cstrong\u003e±10 µm\u003c\/strong\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBlade Angle\u003c\/td\u003e\n\u003ctd\u003eFixed\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eUser Interface\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e4.3-inch color LCD touchscreen\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDisplay Resolution\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e480 × 272 pixels\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRemote Control\u003c\/td\u003e\n\u003ctd\u003eBluetooth wireless remote\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eData Interface\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003eUSB 2.0\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAdministrator Access\u003c\/td\u003e\n\u003ctd\u003ePassword protected\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDimensions\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e16.5\"W × 26.4\"D × 17.4\"H\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMetric Dimensions\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e42 × 67 × 44 cm\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight\u003c\/td\u003e\n\u003ctd\u003eApprox. \u003cstrong\u003e121 lb. \/ 55 kg\u003c\/strong\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eElectrical\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e115VAC ±10%, 50\/60 Hz, 7.1 A\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRegulatory Status\u003c\/td\u003e\n\u003ctd\u003eIVD, FDA Class I\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCondition\u003c\/td\u003e\n\u003ctd\u003eUsed \/ Refurbished\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSupplier\u003c\/td\u003e\n\u003ctd\u003eAmerican Instrument Exchange\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3\u003eCommon Applications\u003c\/h3\u003e\n\u003cp\u003eThe Sakura Tissue-Tek AutoSection 5010 is designed primarily for \u003cstrong\u003esectioning paraffin-embedded tissue specimens for routine and research histology\u003c\/strong\u003e. Typical applications include surgical pathology, anatomical pathology, cancer research, immunohistochemistry, histopathology, pharmaceutical research, toxicology studies, veterinary pathology, academic research, and other workflows requiring repeatable thin sections from paraffin blocks.\u003c\/p\u003e\n\u003cp\u003eIts programmable operation is particularly useful in laboratories processing multiple tissue types or where standardized sectioning protocols are desirable.\u003c\/p\u003e\n\u003ch3\u003eIdeal Laboratory Types\u003c\/h3\u003e\n\u003cp\u003eThe Sakura Tissue-Tek AutoSection 5010 Automated Microtome is well suited for hospital pathology laboratories, reference laboratories, academic medical centers, biotechnology companies, pharmaceutical research laboratories, contract research organizations, veterinary pathology laboratories, cancer research centers, toxicology facilities, and other high-volume histology environments.\u003c\/p\u003e\n\u003cp\u003eIt can be especially valuable in laboratories seeking to reduce the physical demands of repetitive manual microtomy while improving consistency among multiple histotechnologists.\u003c\/p\u003e\n\u003ch3\u003eAutoAlign Automatic Block Orientation\u003c\/h3\u003e\n\u003cp\u003eOne of the most important features of the Tissue-Tek AutoSection is Sakura's \u003cstrong\u003eAutoAlign technology\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003eTraditional microtomy requires the technician to manually orient a paraffin block so the previously cut surface is parallel with the blade.\u003c\/p\u003e\n\u003cp\u003eIf a block was originally faced on another microtome, its cutting surface may not align perfectly with the new blade.\u003c\/p\u003e\n\u003cp\u003eA technician may therefore need to trim away additional paraffin—and potentially tissue—before obtaining a complete section.\u003c\/p\u003e\n\u003cp\u003eThe AutoSection approaches this problem differently.\u003c\/p\u003e\n\u003cp\u003eA sensing plate evaluates the orientation of the block face, while the motorized 3D specimen holder adjusts the block relative to the blade.\u003c\/p\u003e\n\u003cp\u003eThis allows the system to automatically align an existing cut surface with the new blade edge.\u003c\/p\u003e\n\u003ch3\u003ePreserving Valuable Tissue\u003c\/h3\u003e\n\u003cp\u003eAutomatic alignment is particularly valuable when working with:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eSmall biopsies\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eLimited tumor samples\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eCore biopsies\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eResearch specimens\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003ePreviously sectioned blocks\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eArchival specimens\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eTissue intended for molecular testing\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eWhen tissue is limited, every unnecessary trimming pass removes material that cannot be recovered.\u003c\/p\u003e\n\u003cp\u003eBy aligning the block to its existing cut surface, the AutoSection can reduce the amount of material that must be removed simply to re-establish a cutting plane.\u003c\/p\u003e\n\u003ch3\u003ePrecision 3D Specimen Holder\u003c\/h3\u003e\n\u003cp\u003eThe Sakura Tissue-Tek AutoSection 5010 Automated Microtome's specimen holder can automatically adjust the block in both the vertical and horizontal axes.\u003c\/p\u003e\n\u003cp\u003eThe adjustment range is approximately:\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e±4 degrees\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ewith an angular resolution of approximately:\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e0.05 degree\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003eThis fine control enables the system to correct relatively small differences in block orientation.\u003c\/p\u003e\n\u003cp\u003eThe result is a substantially different workflow from a conventional manually adjustable cassette clamp.\u003c\/p\u003e\n\u003ch3\u003eAutoTrim One-Touch Block Facing\u003c\/h3\u003e\n\u003cp\u003eThe AutoTrim function automates one of the most repetitive tasks in histology: facing paraffin blocks.\u003c\/p\u003e\n\u003cp\u003eOnce the specimen is loaded and aligned, AutoTrim advances the block and removes excess paraffin until an appropriate tissue surface is reached.\u003c\/p\u003e\n\u003cp\u003eSakura states that blocks can be faced in approximately \u003cstrong\u003e15 seconds or less\u003c\/strong\u003e under appropriate conditions.\u003c\/p\u003e\n\u003cp\u003eOne-touch trimming reduces the repeated coarse-feed and handwheel operations associated with conventional block facing.\u003c\/p\u003e\n\u003ch3\u003eAdjustable Trimming Thickness\u003c\/h3\u003e\n\u003cp\u003eThe Sakura Tissue-Tek AutoSection 5010 Automated Microtome provides a broad trimming range of:\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e1–200 microns\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis allows the amount of material removed with each trimming pass to be adjusted according to the specimen and laboratory protocol.\u003c\/p\u003e\n\u003cp\u003eLarger trimming increments can accelerate removal of excess paraffin, while smaller increments give technicians greater control when approaching valuable tissue.\u003c\/p\u003e\n\u003ch3\u003eAutomated Sectioning\u003c\/h3\u003e\n\u003cp\u003eOnce a block has been aligned and faced, the AutoSection can perform microtomy automatically.\u003c\/p\u003e\n\u003cp\u003eInstead of requiring continuous handwheel rotation, the operator can initiate sectioning electronically.\u003c\/p\u003e\n\u003cp\u003eThe microtome then advances the specimen according to the selected section thickness, speed, retraction, and protocol parameters.\u003c\/p\u003e\n\u003cp\u003eThe histotechnologist can concentrate on monitoring section quality and handling the ribbon rather than continuously generating the cutting stroke manually.\u003c\/p\u003e\n\u003ch3\u003e0.5–100 Micron Section Thickness Range\u003c\/h3\u003e\n\u003cp\u003eThe AutoSection offers a wide sectioning range of:\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e0.5 to 100 µm\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003eRoutine paraffin histology commonly uses relatively thin sections, but the broader range allows the instrument to support specialized research and preparation requirements as well.\u003c\/p\u003e\n\u003cp\u003eSection thickness can be standardized as part of a programmed protocol, reducing reliance on manual setting changes between specimen types.\u003c\/p\u003e\n\u003ch3\u003eProgrammable Sectioning Protocols\u003c\/h3\u003e\n\u003cp\u003eThe AutoSection can store up to:\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e15 presets\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ewith as many as:\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e16 protocol steps\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis allows laboratories to develop specific sectioning procedures for different specimens or workflows.\u003c\/p\u003e\n\u003cp\u003ePrograms can control variables such as:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eSection thickness\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eCutting speed\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eTrimming parameters\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eRetraction\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eNumber or sequence of cuts\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eOnce an appropriate procedure has been established, technicians can select the stored protocol instead of manually recreating the settings each time.\u003c\/p\u003e\n\u003ch3\u003eStandardization Across the Histology Laboratory\u003c\/h3\u003e\n\u003cp\u003eProgrammable microtomy can be particularly useful in laboratories employing multiple histotechnologists.\u003c\/p\u003e\n\u003cp\u003eWith a conventional manual microtome, individual operators may naturally develop slightly different approaches to:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eFacing\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eCutting speed\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eSection thickness\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eRetraction\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eBlock orientation\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe AutoSection allows many of these parameters to be incorporated into standardized protocols.\u003c\/p\u003e\n\u003cp\u003eThis can help laboratories reduce operator-dependent variation and create more consistent sectioning workflows.\u003c\/p\u003e\n\u003ch3\u003eUp to 32 User Preferences\u003c\/h3\u003e\n\u003cp\u003eThe instrument can store up to \u003cstrong\u003e32 user preferences\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003eThis allows individual technicians to retain preferred operating settings while the laboratory maintains standardized sectioning protocols.\u003c\/p\u003e\n\u003cp\u003eFor large pathology laboratories operating multiple shifts, individualized preferences can reduce the amount of setup required when technicians change workstations.\u003c\/p\u003e\n\u003ch3\u003eAdjustable Sectioning Speed\u003c\/h3\u003e\n\u003cp\u003eSectioning, trimming, and return speed can be programmed from approximately:\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e10 to 450 mm\/second\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003eDifferent tissue types can respond differently to cutting speed.\u003c\/p\u003e\n\u003cp\u003eA slower speed may be useful with challenging or delicate blocks, while routine material may tolerate faster operation.\u003c\/p\u003e\n\u003cp\u003eProgrammable speed gives the laboratory greater control over sectioning behavior.\u003c\/p\u003e\n\u003ch3\u003eAdjustable Retraction\u003c\/h3\u003e\n\u003cp\u003eThe Sakura Tissue-Tek AutoSection 5010 Automated Microtome can operate with no specimen retraction or with a programmable retraction distance between approximately:\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e20 and 100 microns\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003eDuring retraction, the specimen moves slightly away from the blade during the return stroke.\u003c\/p\u003e\n\u003cp\u003eThis can help limit unnecessary contact between the block and blade as the specimen returns to its starting position.\u003c\/p\u003e\n\u003cp\u003eThe appropriate setting depends on tissue characteristics, blade condition, and laboratory preference.\u003c\/p\u003e\n\u003ch3\u003eReducing Repetitive Motion\u003c\/h3\u003e\n\u003cp\u003eTraditional rotary microtomy requires technicians to repeatedly rotate a handwheel.\u003c\/p\u003e\n\u003cp\u003eIn a high-volume pathology laboratory, this motion can be performed hundreds or thousands of times during a shift.\u003c\/p\u003e\n\u003cp\u003eThe AutoSection replaces much of that continuous manual rotation with powered trimming and sectioning.\u003c\/p\u003e\n\u003cp\u003eThis can reduce repetitive upper-extremity motion and may improve ergonomics for technicians performing substantial amounts of daily microtomy.\u003c\/p\u003e\n\u003ch3\u003eMicrotome Ergonomics\u003c\/h3\u003e\n\u003cp\u003eMicrotomy can involve repetitive movements of the:\u003c\/p\u003e\n\u003cp\u003eHand\u003cbr\u003eWrist\u003cbr\u003eElbow\u003cbr\u003eShoulder\u003c\/p\u003e\n\u003cp\u003eas well as prolonged seated positioning.\u003c\/p\u003e\n\u003cp\u003eAutomating cutting motion does not eliminate the need for good ergonomic practices, but it removes one of the most repetitive mechanical components of conventional sectioning.\u003c\/p\u003e\n\u003cp\u003eThis is particularly relevant for high-throughput histology laboratories where microtomy represents a substantial portion of the working day.\u003c\/p\u003e\n\u003ch3\u003eWireless Handheld Remote\u003c\/h3\u003e\n\u003cp\u003eThe AutoSection 5010 includes support for a \u003cstrong\u003eBluetooth wireless handheld remote control\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003eThe remote allows operators to control the instrument from either side rather than being constrained to a fixed control position.\u003c\/p\u003e\n\u003cp\u003eThis can improve ergonomics and allow technicians to select a working position that better fits their preferred ribbon-handling technique.\u003c\/p\u003e\n\u003ch3\u003e4.3-Inch Color Touchscreen\u003c\/h3\u003e\n\u003cp\u003eA \u003cstrong\u003e4.3-inch color LCD touchscreen\u003c\/strong\u003e provides access to operating controls and program settings.\u003c\/p\u003e\n\u003cp\u003eThe interface allows users to:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eSelect protocols\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eAdjust cutting settings\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eControl trimming\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eInitiate sectioning\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eManage preferences\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eReview operating parameters\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAdministrator functions can also be password protected to prevent unauthorized changes to laboratory-defined settings.\u003c\/p\u003e\n\u003ch3\u003eHigh- and Low-Profile Disposable Blades\u003c\/h3\u003e\n\u003cp\u003eThe Tissue-Tek AutoSection is compatible with commonly used disposable microtome blade formats, including high-profile and low-profile blades when properly configured.\u003c\/p\u003e\n\u003cp\u003eSakura offers compatible Accu-Edge and Feather blade options for the system.\u003c\/p\u003e\n\u003cp\u003eDisposable blades provide a fresh cutting edge without the sharpening and maintenance associated with traditional reusable microtome knives.\u003c\/p\u003e\n\u003ch3\u003eBlade-Handling Safety\u003c\/h3\u003e\n\u003cp\u003eMicrotome blades are extremely sharp and represent one of the most significant hazards in histology.\u003c\/p\u003e\n\u003cp\u003eSakura designed the AutoSection blade system to minimize unnecessary direct blade handling.\u003c\/p\u003e\n\u003cp\u003eThe instrument's automated motion and integrated safety features also reduce the amount of manual interaction with the cutting mechanism compared with a conventional microtome.\u003c\/p\u003e\n\u003cp\u003eUsers should still follow appropriate blade-handling procedures and ensure the cutting mechanism is secured before changing blocks, cleaning the instrument, or performing maintenance.\u003c\/p\u003e\n\u003ch3\u003eSection Thickness Consistency\u003c\/h3\u003e\n\u003cp\u003eConsistent section thickness is critical to downstream histology.\u003c\/p\u003e\n\u003cp\u003eVariation in thickness can affect:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eH\u0026amp;E staining\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eImmunohistochemistry\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eMicroscopic appearance\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eOptical density\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eDigital image analysis\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eQuantitative pathology\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSakura reports that automated microtomy with the AutoSection has demonstrated highly precise section thickness compared with manual and motorized microtomy in testing involving immunohistochemistry and digital imaging.\u003c\/p\u003e\n\u003cp\u003eThis makes reproducible sectioning particularly attractive for laboratories moving toward standardized staining and digital pathology workflows.\u003c\/p\u003e\n\u003ch3\u003eSakura Tissue-Tek AutoSection 5010 Automated Microtome Immunohistochemistry Applications\u003c\/h3\u003e\n\u003cp\u003eSection thickness can influence apparent staining intensity during immunohistochemistry.\u003c\/p\u003e\n\u003cp\u003eIf one section contains significantly more tissue than another because of thickness variation, quantitative or semi-quantitative staining comparisons can become more difficult.\u003c\/p\u003e\n\u003cp\u003eAutomated, programmable sectioning can help reduce one source of variability before the slide ever reaches the staining platform.\u003c\/p\u003e\n\u003cp\u003eFor laboratories performing high volumes of IHC, improved consistency during microtomy can complement standardized tissue processing, staining, imaging, and interpretation.\u003c\/p\u003e\n\u003ch3\u003eDigital Pathology \u0026amp; Image Analysis\u003c\/h3\u003e\n\u003cp\u003eDigital pathology places additional emphasis on section consistency.\u003c\/p\u003e\n\u003cp\u003eWhole-slide scanners capture the complete tissue section, making defects such as:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eChatter\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eFolds\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eVariable thickness\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eIncomplete sections\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eCompression\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eparticularly visible.\u003c\/p\u003e\n\u003cp\u003eAlthough successful section quality still depends on proper processing, embedding, blade condition, block temperature, and technician technique, greater control over cutting parameters can support a more standardized digital pathology workflow.\u003c\/p\u003e\n\u003ch3\u003eRoutine Surgical Pathology\u003c\/h3\u003e\n\u003cp\u003eIn a routine surgical pathology laboratory, the AutoSection 5010 can support processing of paraffin blocks from:\u003c\/p\u003e\n\u003cp\u003eBiopsies\u003cbr\u003eResections\u003cbr\u003eGI specimens\u003cbr\u003eBreast tissue\u003cbr\u003eDermatology specimens\u003cbr\u003eProstate specimens\u003cbr\u003eGynecologic specimens\u003cbr\u003eGeneral surgical pathology\u003c\/p\u003e\n\u003cp\u003eAutomated alignment can be especially valuable when blocks are transferred between microtomes or returned for additional sectioning.\u003c\/p\u003e\n\u003ch3\u003eResearch Histology with the Sakura Tissue-Tek AutoSection 5010 Automated Microtome\u003c\/h3\u003e\n\u003cp\u003eResearch laboratories often require precise control over sectioning parameters.\u003c\/p\u003e\n\u003cp\u003eThe ability to program thickness, speed, trimming, and other variables makes the AutoSection useful for studies where specimens need to be prepared consistently across experimental groups.\u003c\/p\u003e\n\u003cp\u003ePotential research applications include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eOncology\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eToxicology\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eDrug development\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eBiomarker research\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eVeterinary pathology\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eNeuroscience\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eTissue morphology\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eTranslational medicine\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eTissue-Tek Paraform Cassette Compatibility\u003c\/h3\u003e\n\u003cp\u003eThe Sakura Tissue-Tek AutoSection 5010 Automated Microtome's automated trimming and alignment capabilities are optimized for Sakura's Tissue-Tek Paraform sectionable cassette system.\u003c\/p\u003e\n\u003cp\u003eWith this system, embedded tissue can remain associated with a sectionable cassette design that supports automation.\u003c\/p\u003e\n\u003cp\u003eHowever, the AutoSection also accommodates \u003cstrong\u003emost conventional histology cassettes\u003c\/strong\u003e, making it practical for laboratories that are not operating a complete Sakura Paraform workflow.\u003c\/p\u003e\n\u003ch3\u003eAutoSection vs. Manual Rotary Microtome\u003c\/h3\u003e\n\u003cp\u003eA conventional manual rotary microtome gives an experienced histotechnologist direct mechanical control over every cutting stroke.\u003c\/p\u003e\n\u003cp\u003eIt is simple, familiar, and appropriate for many laboratories.\u003c\/p\u003e\n\u003cp\u003eThe AutoSection adds automation in several areas:\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBlock alignment\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003eBlock facing\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003eSectioning motion\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003eProtocol control\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003eSpeed control\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003eUser settings\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe primary advantages are consistency, tissue preservation, workflow standardization, and reduced repetitive handwheel motion.\u003c\/p\u003e\n\u003ch3\u003eAutoSection vs. Motorized Microtome\u003c\/h3\u003e\n\u003cp\u003eA motorized microtome automates the cutting stroke but may still require substantial manual block orientation and facing.\u003c\/p\u003e\n\u003cp\u003eThe Tissue-Tek AutoSection goes further.\u003c\/p\u003e\n\u003cp\u003eIts \u003cstrong\u003e3D specimen holder and sensing system automatically align the block to the blade\u003c\/strong\u003e, while AutoTrim automates the facing process.\u003c\/p\u003e\n\u003cp\u003eFor laboratories comparing automated versus motorized microtomes, this block-orientation capability is one of the most important distinctions of the Sakura 5010.\u003c\/p\u003e\n\u003ch3\u003eProductivity in High-Volume Histology\u003c\/h3\u003e\n\u003cp\u003eNo single instrument eliminates the need for skilled histotechnologists.\u003c\/p\u003e\n\u003cp\u003eSection quality still depends on understanding:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eTissue processing\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eParaffin quality\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eEmbedding orientation\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eBlock temperature\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eBlade selection\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eRibbon handling\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe advantage of the AutoSection is that many mechanical aspects of the process can be standardized and automated.\u003c\/p\u003e\n\u003cp\u003eThis allows the histotechnologist to focus more attention on evaluating tissue and section quality rather than repeatedly performing coarse mechanical movements.\u003c\/p\u003e\n\u003ch3\u003eCompact Benchtop Footprint\u003c\/h3\u003e\n\u003cp\u003eDespite its extensive automation, the AutoSection remains a benchtop instrument.\u003c\/p\u003e\n\u003cp\u003eOverall dimensions are approximately:\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e16.5\"W × 26.4\"D × 17.4\"H\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ewith a weight of approximately:\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e121 lb. \/ 55 kg\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003eThe depth is greater than many conventional manual microtomes, so laboratories should confirm available bench space before installation.\u003c\/p\u003e\n\u003cp\u003eAdequate clearance should also be maintained for operation, cleaning, and access to the rear of the instrument.\u003c\/p\u003e\n\u003ch3\u003eElectrical Requirements\u003c\/h3\u003e\n\u003cp\u003eThe Tissue-Tek AutoSection 5010 operates on:\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e115VAC ±10%, 50\/60 Hz, 7.1 A\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003efor the U.S. configuration.\u003c\/p\u003e\n\u003cp\u003eElectrical service should be verified against the data plate on the individual instrument before installation.\u003c\/p\u003e\n\u003cp\u003eA stable, properly grounded laboratory electrical supply is recommended for reliable operation of the motorized and electronic systems.\u003c\/p\u003e\n\u003ch3\u003eCleaning \u0026amp; Routine Maintenance\u003c\/h3\u003e\n\u003cp\u003eParaffin debris is unavoidable during routine microtomy.\u003c\/p\u003e\n\u003cp\u003eRegular cleaning helps prevent accumulation around the blade holder, specimen mechanism, and working surfaces.\u003c\/p\u003e\n\u003cp\u003eCleaning procedures should be performed with the instrument in an appropriate safe state and with the blade removed or secured according to laboratory procedures.\u003c\/p\u003e\n\u003cp\u003eRoutine users should also inspect:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eBlade holder\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eSpecimen chuck\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eWaste collection area\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eTouchscreen\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eRemote\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eMoving mechanisms\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003ePower cord\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eand report any unusual motion, noise, or sectioning behavior.\u003c\/p\u003e\n\u003ch3\u003eRefurbishment \u0026amp; Testing by American Instrument Exchange\u003c\/h3\u003e\n\u003cp\u003eAutomated microtomes contain substantially more electronic and mechanical components than conventional manual microtomes, making thorough functional testing especially important when purchasing refurbished equipment.\u003c\/p\u003e\n\u003cp\u003eAmerican Instrument Exchange evaluates used histology equipment before shipment.\u003c\/p\u003e\n\u003cp\u003eTesting of a Tissue-Tek AutoSection 5010 may include evaluation of:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eInstrument power-up\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eTouchscreen operation\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eSpecimen advance\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eSectioning motion\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eTrimming operation\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eThickness adjustment\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eSpeed control\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e3D specimen-holder movement\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eBlock alignment functions\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eAutoTrim operation\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eAutoSection operation\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eRetraction\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eBlade-holder condition\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eRemote-control operation when included\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eUser controls\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eSafety functions\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eGeneral mechanical operation\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe instrument is cleaned and prepared for laboratory use before shipment.\u003c\/p\u003e\n\u003ch3\u003eWhy Purchase a Refurbished Sakura AutoSection from American Instrument Exchange?\u003c\/h3\u003e\n\u003cp\u003eAutomated histology equipment can represent a significant capital investment.\u003c\/p\u003e\n\u003cp\u003ePurchasing a used and refurbished Sakura Tissue-Tek AutoSection 5010 from \u003cstrong\u003eAmerican Instrument Exchange\u003c\/strong\u003e can allow laboratories to add automated microtomy capability while avoiding the cost of purchasing a comparable new instrument.\u003c\/p\u003e\n\u003cp\u003eAIE supplies refurbished laboratory and pathology equipment to biotechnology, pharmaceutical, clinical, academic, healthcare, and research facilities throughout the United States.\u003c\/p\u003e\n\u003cp\u003eUsed equipment is evaluated before sale so customers can obtain high-quality laboratory instrumentation while extending the useful service life of existing equipment.\u003c\/p\u003e\n\u003ch3\u003eShipping \u0026amp; Installation\u003c\/h3\u003e\n\u003cp\u003eAt approximately \u003cstrong\u003e121 lb.\u003c\/strong\u003e, the AutoSection is significantly heavier than many manual rotary microtomes.\u003c\/p\u003e\n\u003cp\u003eThe instrument should be transported and lifted using appropriate equipment and sufficient personnel.\u003c\/p\u003e\n\u003cp\u003eBefore installation, laboratories should confirm:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eBench capacity\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eAvailable bench depth\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eElectrical service\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eOperator clearance\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eWorkspace for ribbon handling\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eBlade and cassette supplies\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eAccess for cleaning and maintenance\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe microtome should be positioned on a stable, level laboratory surface to support consistent operation.\u003c\/p\u003e\n\u003ch3\u003eRelated Laboratory Equipment\u003c\/h3\u003e\n\u003cp\u003eHistology laboratories using the Sakura Tissue-Tek AutoSection may also require \u003cstrong\u003etissue processors, embedding centers, paraffin dispensers, slide warmers, flotation baths, cryostats, automated slide stainers, coverslippers, cassette printers, slide printers, microscopes, laboratory refrigerators, and other pathology equipment\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003eAmerican Instrument Exchange supplies used and refurbished laboratory and histology equipment for clinical pathology, pharmaceutical research, biotechnology, veterinary medicine, academic research, and other laboratory environments.\u003c\/p\u003e\n\u003ch3\u003eSakura Tissue-Tek AutoSection 5010 Frequently Asked Questions\u003c\/h3\u003e\n\u003ch4\u003eWhat is the Sakura Tissue-Tek AutoSection 5010?\u003c\/h4\u003e\n\u003cp\u003eThe AutoSection 5010 is a \u003cstrong\u003efully automated microtome designed for sectioning paraffin-embedded tissue specimens in routine and research histology\u003c\/strong\u003e.\u003c\/p\u003e\n\u003ch4\u003eIs the AutoSection 5010 a rotary microtome?\u003c\/h4\u003e\n\u003cp\u003eIt performs the same fundamental paraffin-sectioning function as a rotary microtome but adds automated block alignment, automated trimming, powered sectioning, programmable protocols, and a motorized 3D specimen holder.\u003c\/p\u003e\n\u003ch4\u003eWhat is the section thickness range?\u003c\/h4\u003e\n\u003cp\u003eThe AutoSection can produce sections from approximately \u003cstrong\u003e0.5 to 100 microns\u003c\/strong\u003e.\u003c\/p\u003e\n\u003ch4\u003eWhat is the trimming thickness range?\u003c\/h4\u003e\n\u003cp\u003eTrimming can be programmed from approximately \u003cstrong\u003e1 to 200 microns\u003c\/strong\u003e.\u003c\/p\u003e\n\u003ch4\u003eWhat is AutoAlign?\u003c\/h4\u003e\n\u003cp\u003eAutoAlign uses a sensing system and motorized 3D specimen holder to align the existing block surface with the blade edge automatically.\u003c\/p\u003e\n\u003ch4\u003eWhy is automatic block alignment useful?\u003c\/h4\u003e\n\u003cp\u003eIt can reduce the amount of paraffin and tissue that must be removed when a previously faced block is transferred from another microtome.\u003c\/p\u003e\n\u003ch4\u003eWhat is AutoTrim?\u003c\/h4\u003e\n\u003cp\u003eAutoTrim is Sakura's automated block-facing function. It can face compatible blocks in approximately \u003cstrong\u003e15 seconds or less\u003c\/strong\u003e under appropriate conditions.\u003c\/p\u003e\n\u003ch4\u003eDoes the AutoSection automatically cut sections?\u003c\/h4\u003e\n\u003cp\u003eYes. The AutoSection function provides powered, programmable microtomy at the touch of a control rather than requiring continuous manual handwheel rotation.\u003c\/p\u003e\n\u003ch4\u003eWhat is the sectioning speed range?\u003c\/h4\u003e\n\u003cp\u003eSectioning speed is adjustable from approximately \u003cstrong\u003e10 to 450 mm\/sec\u003c\/strong\u003e.\u003c\/p\u003e\n\u003ch4\u003eCan trimming speed be adjusted?\u003c\/h4\u003e\n\u003cp\u003eYes. Trimming and return speeds are also adjustable from approximately \u003cstrong\u003e10 to 450 mm\/sec\u003c\/strong\u003e.\u003c\/p\u003e\n\u003ch4\u003eDoes the specimen retract during the return stroke?\u003c\/h4\u003e\n\u003cp\u003eRetraction can be disabled or programmed between approximately \u003cstrong\u003e20 and 100 microns\u003c\/strong\u003e.\u003c\/p\u003e\n\u003ch4\u003eHow far can the specimen holder adjust?\u003c\/h4\u003e\n\u003cp\u003eThe 3D chuck provides approximately \u003cstrong\u003e±4 degrees of adjustment on its vertical and horizontal axes\u003c\/strong\u003e.\u003c\/p\u003e\n\u003ch4\u003eHow precise is specimen orientation?\u003c\/h4\u003e\n\u003cp\u003eThe specimen-holder angle resolution is approximately \u003cstrong\u003e0.05 degree\u003c\/strong\u003e.\u003c\/p\u003e\n\u003ch4\u003eHow many sectioning presets can be stored?\u003c\/h4\u003e\n\u003cp\u003eUp to \u003cstrong\u003e15 presets\u003c\/strong\u003e can be stored.\u003c\/p\u003e\n\u003ch4\u003eHow many steps can a sectioning protocol contain?\u003c\/h4\u003e\n\u003cp\u003eA protocol can contain up to \u003cstrong\u003e16 steps\u003c\/strong\u003e.\u003c\/p\u003e\n\u003ch4\u003eCan multiple technicians save preferences?\u003c\/h4\u003e\n\u003cp\u003eYes. The instrument supports up to \u003cstrong\u003e32 user preferences\u003c\/strong\u003e.\u003c\/p\u003e\n\u003ch4\u003eDoes the AutoSection have a touchscreen?\u003c\/h4\u003e\n\u003cp\u003eYes. The 5010 uses a \u003cstrong\u003e4.3-inch color LCD touchscreen\u003c\/strong\u003e.\u003c\/p\u003e\n\u003ch4\u003eDoes it have a remote control?\u003c\/h4\u003e\n\u003cp\u003eYes. The AutoSection supports a \u003cstrong\u003eBluetooth wireless handheld remote\u003c\/strong\u003e, allowing operation from either side of the instrument.\u003c\/p\u003e\n\u003ch4\u003eDoes the AutoSection work with regular histology cassettes?\u003c\/h4\u003e\n\u003cp\u003eYes. Although optimized for Sakura's Paraform system, it accommodates most commonly used histology cassettes.\u003c\/p\u003e\n\u003ch4\u003eWhat type of blades does the 5010 use?\u003c\/h4\u003e\n\u003cp\u003eThe system supports compatible disposable microtome blades, including appropriate high- and low-profile Sakura Accu-Edge and Feather blade formats.\u003c\/p\u003e\n\u003ch4\u003eIs the AutoSection useful for IHC laboratories?\u003c\/h4\u003e\n\u003cp\u003eYes. Consistent section thickness is important for immunohistochemistry because tissue-section thickness can influence staining intensity and microscopic interpretation.\u003c\/p\u003e\n\u003ch4\u003eIs the 5010 useful for digital pathology?\u003c\/h4\u003e\n\u003cp\u003eYes. Greater control over sectioning parameters and thickness consistency can support standardized slide preparation for whole-slide imaging and quantitative image analysis.\u003c\/p\u003e\n\u003ch4\u003eDoes automated microtomy eliminate the need for a histotechnologist?\u003c\/h4\u003e\n\u003cp\u003eNo. Skilled operators remain essential for evaluating tissue processing, embedding, block temperature, blade condition, ribbon quality, and final section quality. The AutoSection automates many mechanical and repetitive steps.\u003c\/p\u003e\n\u003ch4\u003eCan the AutoSection reduce repetitive motion?\u003c\/h4\u003e\n\u003cp\u003eYes. Powered trimming and sectioning reduce the continuous handwheel rotation required with a traditional manual microtome.\u003c\/p\u003e\n\u003ch4\u003eWhat are the dimensions of the Sakura 5010?\u003c\/h4\u003e\n\u003cp\u003eThe instrument measures approximately \u003cstrong\u003e16.5\"W × 26.4\"D × 17.4\"H\u003c\/strong\u003e.\u003c\/p\u003e\n\u003ch4\u003eHow much does the AutoSection 5010 weigh?\u003c\/h4\u003e\n\u003cp\u003eApproximately \u003cstrong\u003e121 lb. \/ 55 kg\u003c\/strong\u003e.\u003c\/p\u003e\n\u003ch4\u003eWhat electrical service does the U.S. model require?\u003c\/h4\u003e\n\u003cp\u003eThe U.S. specification is approximately \u003cstrong\u003e115VAC ±10%, 50\/60 Hz, 7.1 A\u003c\/strong\u003e.\u003c\/p\u003e\n\u003ch4\u003eWhat specimens can be sectioned with the AutoSection?\u003c\/h4\u003e\n\u003cp\u003eThe instrument is designed for \u003cstrong\u003eparaffin-embedded specimens used in routine and research histology\u003c\/strong\u003e.\u003c\/p\u003e\n\u003ch4\u003eIs the Sakura AutoSection 5010 available refurbished?\u003c\/h4\u003e\n\u003cp\u003eYes. American Instrument Exchange offers used and refurbished laboratory and pathology equipment, including automated microtomes such as the Sakura Tissue-Tek AutoSection 5010.\u003c\/p\u003e\n\u003ch4\u003eHow does American Instrument Exchange test a refurbished AutoSection?\u003c\/h4\u003e\n\u003cp\u003eAIE evaluates major mechanical and electronic functions including specimen movement, sectioning, trimming, thickness controls, automated alignment functions, touchscreen operation, and general system performance before shipment.\u003c\/p\u003e","brand":"Sakura","offers":[{"title":"Default Title","offer_id":43597773963312,"sku":"3501C MICROTOME","price":8400.0,"currency_code":"USD","in_stock":false}],"url":"https:\/\/www.americaninstrument.com\/products\/sakura-tissue-tek-autosection-5010-automated-microtome","provider":"American Instrument Exchange","version":"1.0","type":"link"}