Mettler Toledo XS105 Analytical Balance – Used & Refurbished
The Mettler Toledo XS105 Analytical Balance is a high-resolution laboratory balance designed for demanding quantitative applications requiring substantially greater sensitivity than a conventional 0.1 mg analytical balance. With a 120 g maximum capacity and 0.01 mg (10 µg) readability, the XS105 is well suited for pharmaceutical research, analytical chemistry, standards preparation, formulation, gravimetric analysis, quality control, and other procedures involving small samples and precise mass determination.
Available used and refurbished from American Instrument Exchange, the Mettler Toledo XS105 provides laboratories with proven Excellence-series weighing technology at a significantly lower acquisition cost than comparable new high-resolution balances. Each XS105 is inspected, cleaned, calibrated, and tested for weighing accuracy and repeatability before shipment and includes a 90-day warranty from American Instrument Exchange.
Key Features
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120 g maximum weighing capacity
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0.01 mg / 10 µg readability
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Typical repeatability of approximately 0.008 mg / 8 µg
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Typical USP minimum weight of approximately 16 mg
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±0.2 mg linearity
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Approximately 3-second settling time
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FACT automatic internal adjustment
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SmartGrid weighing pan minimizes turbulence inside the weighing chamber
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Enclosed draft shield protects high-resolution measurements from air movement
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ErgoClip compatibility for secure placement of different weighing vessels
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Detachable terminal allows flexible workstation configuration
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Tool-free removable draft shield components simplify cleaning
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LabX software compatibility
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Used, refurbished, calibrated, and tested by American Instrument Exchange
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90-day warranty included
Overview
The Mettler Toledo XS105 is not a conventional 0.1 mg analytical balance. Its 0.01 mg, or 10 µg, readability provides ten times finer resolution, placing the XS105 in the high-resolution analytical range between standard analytical balances and dedicated microbalances.
That combination of resolution and 120 g capacity makes the XS105 particularly useful for laboratories working with small quantities but still requiring enough capacity for conventional weighing vessels, containers, filters, and other analytical samples.
Mettler Toledo designed the XS series to address some of the practical difficulties associated with high-resolution weighing. Its SmartGrid weighing pan minimizes turbulence within the weighing chamber, helping measurements stabilize more rapidly. The enclosed draft shield protects the weighing system from room air currents, while the open-grid pan design reduces the amount of solid surface area exposed to moving air.
The balance also incorporates FACT automatic internal adjustment, helping maintain weighing performance as environmental conditions change.
For laboratories that need greater sensitivity than a standard analytical balance but do not require the 1 µg readability of a dedicated microbalance, the XS105 offers a particularly useful combination of 10 µg resolution, 120 g capacity, ergonomic sample handling, and proven Mettler Toledo weighing technology.
Common Applications
The Mettler Toledo XS105 is particularly well suited for applications involving small samples and high-resolution quantitative measurements.
Pharmaceutical and biotechnology laboratories can use the XS105 for standards preparation, formulation research, active ingredient weighing, reagent preparation, sample preparation, quality control, and other procedures where small differences in mass must be measured reliably.
Analytical chemistry laboratories may use the XS105 for gravimetric analysis, solution preparation, reference-standard preparation, differential weighing, density determination, filter weighing, and other high-resolution quantitative procedures.
Environmental laboratories can use the balance for filter and particulate measurements, while materials science and academic research laboratories may use it for small-sample preparation, comparative weighing, material characterization, and experimental work.
Its combination of 10 µg readability and a relatively generous 120 g capacity also makes the XS105 useful when laboratories need high resolution without the significantly smaller capacities typically associated with true microbalances.
Ideal Laboratory Types
The XS105 is a strong choice for pharmaceutical, biotechnology, analytical chemistry, environmental testing, materials science, academic research, formulation, manufacturing, and quality-control laboratories.
It is particularly appropriate for laboratories that have reached the practical limits of conventional 0.1 mg analytical balances.
For organizations routinely weighing small samples or preparing low-concentration standards, the tenfold improvement in displayed resolution can provide a meaningful advantage. At the same time, the 120 g maximum capacity gives operators considerably more flexibility than many dedicated microbalances.
This makes the XS105 useful as either a primary high-resolution analytical balance or as a specialized instrument alongside standard analytical and precision balances.
High-Resolution Analytical Weighing Performance
The defining feature of the Mettler Toledo XS105 is its 0.01 mg, or 10 µg, readability.
Mettler Toledo specifies typical repeatability of approximately 0.008 mg, or 8 µg, along with linearity of ±0.2 mg. Typical settling time is approximately 3 seconds.
These specifications position the XS105 substantially above a conventional analytical balance in terms of resolution while retaining a useful 120 g weighing capacity.
High-resolution performance also means that environmental influences become increasingly important. At the 10 µg level, small disturbances that may be insignificant on a precision balance can become visible in the weighing result.
Mettler Toledo's SmartGrid weighing pan helps address this problem by reducing turbulence within the weighing chamber. Compared with a conventional solid weighing pan, the open-grid design presents less surface area to moving air and allows measurements to stabilize efficiently inside the enclosed draft shield.
For laboratories performing repeated high-resolution measurements, this combination of sensitivity and stabilization can improve both measurement quality and workflow efficiency.
Minimum Sample Weight & USP Applications
Minimum sample weight is a critical consideration when a balance is used for pharmaceutical or other regulated quantitative procedures.
Mettler Toledo specifies a typical USP minimum weight of approximately 16 mg for the XS105 under stated conditions.
This relatively low typical minimum weight reflects the balance's high-resolution weighing performance and makes the XS105 potentially useful for applications involving substantially smaller sample quantities than can generally be handled reliably on a standard 0.1 mg analytical balance.
Actual minimum weight is not determined by readability alone. It depends on the repeatability of the individual installed balance, environmental conditions, installation quality, measurement uncertainty requirements, and applicable laboratory procedures.
For regulated applications, laboratories should establish and document minimum weight according to their own balance qualification procedures and quality system rather than relying exclusively on a manufacturer's typical published value.
Controlling Drafts, Vibration & Static
At 10 µg readability, environmental control becomes an important part of reliable weighing.
Air currents, vibration, temperature gradients, static electricity, unstable work surfaces, and operator technique can all influence high-resolution measurements.
The XS105 uses an enclosed draft shield to isolate the weighing chamber from room air movement. Its SmartGrid weighing pan further reduces turbulence around the sample and helps the weighing system stabilize efficiently.
Static electricity deserves particular attention when weighing powders, filters, plastics, glass vessels, and other materials capable of accumulating electrostatic charge. Electrostatic forces can produce apparent changes in mass that are significant relative to the XS105's 10 µg readability.
Mettler Toledo offered antistatic accessories for the XS series to help neutralize charged samples and containers when static becomes a significant source of measurement error.
For best performance, the XS105 should be installed on a rigid, level, vibration-resistant surface away from HVAC vents, doors, direct sunlight, centrifuges, shakers, refrigeration compressors, and other sources of vibration or temperature fluctuation.
A dedicated balance table or anti-vibration workstation may be beneficial when the instrument is routinely used near the lower end of its weighing range.
Calibration & Internal Adjustment
The XS105 incorporates Mettler Toledo's FACT automatic internal adjustment system.
FACT helps compensate for changes in operating conditions by allowing the balance to perform internal adjustment automatically. This reduces reliance on manually initiated adjustment procedures and helps maintain consistent weighing performance throughout routine laboratory operation.
Automatic internal adjustment does not eliminate the need for external performance verification.
Laboratories operating under GLP, GMP, USP, or internal quality systems may require scheduled testing using appropriate traceable calibration weights along with documented accuracy, repeatability, and minimum-weight verification.
American Instrument Exchange evaluates refurbished balances using appropriate calibration weights and verifies critical weighing characteristics before shipment.
SmartGrid, ErgoClips & Sample Handling
High-resolution weighing is influenced not only by the balance itself but also by how the sample and weighing vessel interact with the weighing chamber.
The XS105 uses Mettler Toledo's distinctive SmartGrid weighing pan, designed to reduce the effects of air turbulence and improve stabilization.
Mettler Toledo's ErgoClip accessories can be attached to the SmartGrid to securely support different types of weighing vessels. This allows samples to be weighed directly into appropriate containers while minimizing awkward positioning and unnecessary sample transfers.
Direct weighing into the final container can be particularly valuable when handling expensive compounds, small sample quantities, or materials where transfer losses could significantly affect the final result.
The draft shield can also be disassembled without tools, simplifying access to the weighing chamber for routine cleaning. This is especially useful in pharmaceutical, analytical, and research laboratories where powders and other small particles may accumulate around the weighing area.
Data Management & LabX Compatibility
The XS105 can be integrated into more structured laboratory data workflows through compatibility with Mettler Toledo LabX software.
LabX can support automatic calculations, data storage, reporting, and standardized weighing procedures, helping reduce reliance on manual transcription.
This capability can be especially useful in pharmaceutical, biotechnology, and quality-control laboratories where weighing results become part of formal analytical records.
Laboratories evaluating a refurbished XS105 for integration with existing data systems should confirm software versions, interfaces, licensing, and compatibility with their current laboratory infrastructure.
Key Specifications
| Specification |
Mettler Toledo XS105 |
| Balance Type |
High-Resolution Analytical Balance |
| Maximum Capacity |
120 g |
| Readability |
0.01 mg / 10 µg |
| Typical Repeatability |
0.008 mg / 8 µg |
| Typical USP Minimum Weight |
16 mg |
| Linearity |
±0.2 mg |
| Settling Time |
Approx. 3 seconds |
| Adjustment |
Internal / FACT |
| Weighing Pan |
73 × 78 mm |
| Weighing Pan Technology |
SmartGrid |
| Draft Protection |
Enclosed draft shield |
| Sample Holders |
ErgoClip compatible |
| Display |
Detachable terminal |
| Overall Dimensions |
263 mm W × 453 mm D × 322 mm H |
| Software Compatibility |
LabX |
| Legal for Trade |
No |
Choosing Between an Analytical, Semi-Micro & Microbalance
Choosing between an analytical, semi-micro, and microbalance requires considering more than maximum capacity. The smallest quantity that must be measured reliably is often the more important factor.
A conventional analytical balance commonly provides 0.1 mg readability and is appropriate for a broad range of routine quantitative laboratory procedures.
The XS105 provides 0.01 mg, or 10 µg, readability, giving it ten times finer displayed resolution. This makes it a strong choice for laboratories working with smaller quantities or requiring greater sensitivity than a standard analytical balance can provide.
A dedicated microbalance may provide 1 µg readability, offering another tenfold increase in resolution. That additional sensitivity, however, generally comes with lower capacity, greater environmental sensitivity, and more demanding installation requirements.
The XS105 therefore occupies a valuable middle ground. Laboratories receive near-semi-micro/high-resolution analytical performance while retaining 120 g of weighing capacity.
For extremely small samples where true microgram-level readability is required, a microbalance such as the Mettler Toledo XPE26 may be more appropriate. For routine measurements where 0.1 mg readability is sufficient, a conventional analytical balance may offer a more economical solution.
Refurbishment & Performance Testing
Every used Mettler Toledo XS105 sold by American Instrument Exchange is inspected, cleaned, refurbished as necessary, calibrated, and tested before shipment.
High-resolution analytical balances require substantially more evaluation than a simple power-on test. Our technicians use appropriate calibration weights to check critical performance characteristics including accuracy, repeatability, linearity, corner-load tolerances, stability, and reduced span at or near full capacity.
The FACT internal adjustment system, weighing cell, display, controls, SmartGrid pan, draft shield, leveling components, and other installed features are also inspected and tested for proper operation.
The weighing chamber, SmartGrid, draft shield panels, and other accessible components are thoroughly cleaned before shipment.
Each refurbished XS105 includes a 90-day warranty from American Instrument Exchange.
Shipping & Installation Considerations
A balance capable of resolving 10 µg changes in mass requires careful handling during transportation and thoughtful installation after delivery.
American Instrument Exchange securely prepares the XS105 for shipment to protect the weighing system, SmartGrid pan, draft shield, display, and other components.
Once received, the balance should be installed on a rigid, level, vibration-resistant work surface in an area with stable temperature and minimal air movement. The instrument should be allowed to acclimate to its new laboratory environment before final adjustment, calibration verification, and critical weighing procedures are performed.
For demanding high-resolution applications, a dedicated balance table or anti-vibration workstation should be considered.
Laboratories performing regulated measurements should follow installation with appropriate calibration, verification, minimum-weight determination, or qualification according to their quality system.
Related Laboratory Equipment
American Instrument Exchange maintains an extensive inventory of used and refurbished laboratory balances, including analytical balances, semi-micro balances, microbalances, and precision balances for applications ranging from routine sample preparation to high-resolution quantitative analysis.
Labs developing complete analytical or sample-preparation workflows can also source centrifuges, water baths, incubators, laboratory refrigerators, laboratory freezers, and other refurbished laboratory equipment from American Instrument Exchange.
Mettler Toledo XS105 Analytical Balance FAQs
What is the maximum capacity of the Mettler Toledo XS105?
The XS105 has a maximum weighing capacity of 120 g, providing useful capacity for high-resolution analytical weighing applications.
What is the readability of the XS105?
The Mettler Toledo XS105 provides 0.01 mg, or 10 µg, readability. This is ten times finer than the 0.1 mg readability commonly associated with conventional analytical balances.
What is the typical repeatability of the XS105?
Mettler Toledo specifies typical repeatability of approximately 0.008 mg, or 8 µg, under appropriate operating conditions.
What is the typical USP minimum weight of the XS105?
Mettler Toledo specifies a typical USP minimum weight of approximately 16 mg under stated conditions. Actual minimum weight should be determined according to the installed balance's repeatability, environmental conditions, measurement uncertainty, and laboratory quality requirements.
Is the XS105 an analytical balance or a microbalance?
The XS105 is a high-resolution analytical balance. Its 10 µg readability provides substantially greater resolution than a conventional 0.1 mg analytical balance but does not reach the 1 µg readability typically associated with a dedicated microbalance.
What is SmartGrid on the Mettler Toledo XS105?
SmartGrid is an open-grid weighing pan designed to reduce turbulence within the weighing chamber. By minimizing the effects of moving air around the sample, SmartGrid helps high-resolution measurements stabilize efficiently.
What are ErgoClips?
Mettler Toledo ErgoClips are accessories designed to attach to the SmartGrid weighing pan and securely hold different types of weighing vessels. They can allow samples to be weighed directly into their intended containers, reducing sample transfers and potential material loss.
Does the XS105 have automatic internal calibration?
Yes. The XS105 incorporates FACT automatic internal adjustment, helping maintain weighing performance as environmental conditions change. Laboratories operating under regulated quality systems may still require documented external calibration and performance verification.
Is the XS105 compatible with LabX?
Yes. The XS105 is compatible with Mettler Toledo LabX software, allowing weighing results to be incorporated into automated calculation, data-storage, reporting, and standardized workflow processes when appropriately configured.
Why purchase a refurbished Mettler Toledo XS105?
A refurbished XS105 provides laboratories with 10 µg readability, 120 g capacity, SmartGrid weighing technology, FACT internal adjustment, and LabX compatibility without the acquisition cost associated with comparable new high-resolution analytical balances. American Instrument Exchange tests, calibrates, cleans, and refurbishes each balance before shipment and provides a 90-day warranty.
