QSonica Q500 Ultrasonic Homogenizer with CL-334 Converter, Probe, and Sound Enclosure
The QSonica Q500 Ultrasonic Homogenizer is a programmable 500-watt ultrasonic processor designed for cell disruption, homogenization, nanoparticle dispersion, emulsification, extraction, and sample preparation. This complete refurbished system from American Instrument Exchange includes the QSonica Q500 ultrasonic generator, the CL-334 converter with direct sonication probe, and the QSonica sound enclosure for quieter and safer operation. Delivering 500 watts of ultrasonic power at 20 kHz, the Q500 provides reliable processing for biotechnology, pharmaceutical, academic, clinical, and industrial laboratories requiring reproducible ultrasonic sample preparation.
QSonica Q500 Ultrasonic Homogenizer Key Features
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QSonica Q500 ultrasonic processor
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Includes CL-334 converter assembly
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Includes direct sonication probe
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Includes QSonica sound enclosure
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500-watt ultrasonic output
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20 kHz operating frequency
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Digital microprocessor controls
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Programmable pulse mode
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Adjustable amplitude control (20–100%)
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Programmable timer up to 10 hours
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Real-time wattage and joule display
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Overload protection
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Sound enclosure reduces operating noise by approximately 20 dBA
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Refurbished and tested by American Instrument Exchange
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90-day warranty included from American Instrument Exchange
QSonica Q500 Ultrasonic Homogenizer Overview
The QSonica Q500 is engineered for laboratories requiring high-energy ultrasonic processing with exceptional control and repeatability. Ultrasonic energy is delivered through the CL-334 converter and probe assembly directly into the sample, producing intense cavitation that rapidly disrupts cells, disperses nanoparticles, emulsifies liquids, and homogenizes biological or chemical materials. The digital controller allows users to precisely adjust amplitude, pulse intervals, and processing time while displaying real-time power output and accumulated energy. The included sound enclosure helps reduce laboratory noise exposure while securely supporting the converter and probe assembly during operation.
Common Applications for the QSonica Q500 Ultrasonic Homogenizer
The QSonica Q500 is commonly used for cell lysis, DNA and RNA extraction, protein extraction, bacterial disruption, tissue homogenization, nanoparticle dispersion, liposome preparation, emulsification, pharmaceutical formulation, graphene dispersion, polymer research, environmental sample preparation, and sonochemistry. The programmable operating modes make the system suitable for both routine laboratory processing and research protocols requiring highly reproducible ultrasonic energy delivery.
Ideal Lab Types for the QSonica Q500 Ultrasonic Homogenizer
This ultrasonic homogenizer is well suited for biotechnology companies, pharmaceutical manufacturers, molecular biology laboratories, genomics facilities, proteomics laboratories, university research institutions, environmental laboratories, nanotechnology research groups, and industrial R&D departments. Laboratories utilizing biosafety cabinets, centrifuges, laboratory freezers, PCR equipment, and analytical balances frequently incorporate probe sonicators into sample preparation and extraction workflows.
QSonica Q500 Ultrasonic Homogenizer Key Specifications
| Specification |
Details |
| Manufacturer |
QSonica |
| Model |
Q500 |
| Equipment Type |
Ultrasonic Homogenizer / Probe Sonicator |
| Ultrasonic Power |
500 Watts |
| Operating Frequency |
20 kHz |
| Converter |
CL-334 |
| Probe |
Direct Sonication Probe |
| Amplitude Control |
20–100% |
| Pulse Mode |
Programmable (1 second to 1 minute On/Off) |
| Programmable Timer |
Up to 10 Hours |
| Display |
Digital LCD |
| Energy Display |
Real-Time Wattage and Joules |
| Safety Features |
Overload Protection |
| Generator Dimensions |
8" W × 15.25" D × 8.5" H |
| Sound Enclosure |
Included (approximately 20 dBA noise reduction) |
| Electrical Requirements |
110–120V, 50/60 Hz |
| Condition |
Refurbished |
Specifications compiled from QSonica manufacturer literature, distributor technical references, and American Instrument Exchange product information.
Refurbishment and Testing Process
At American Instrument Exchange, each refurbished ultrasonic homogenizer is inspected and evaluated by our technicians prior to shipment. Testing procedures may include verification of ultrasonic output, converter performance, probe operation, amplitude control, pulse mode functionality, display operation, timer verification, electrical safety testing, and overall system performance. The sound enclosure is inspected for structural integrity and proper operation. Components showing excessive wear are serviced or replaced as needed to help ensure dependable laboratory performance. Final cleaning and inspection are completed before packaging and shipment.
Shipping and Installation Considerations
The QSonica Q500 should be installed on a stable laboratory bench with adequate ventilation around the generator and sufficient workspace for safe sample handling. The included sound enclosure provides a dedicated mounting location for the converter assembly while reducing operator noise exposure during sonication. Buyers should inspect the probe tip periodically for wear and tighten the converter and probe according to the manufacturer's recommendations before operation. The complete system is carefully packaged to protect the generator, converter, probe assembly, and sound enclosure during shipment.
Related Laboratory Equipment
Laboratories purchasing ultrasonic homogenizers often also require biosafety cabinets, centrifuges, laboratory refrigerators, ultra-low temperature freezers, PCR equipment, analytical balances, and vortex mixers. American Instrument Exchange offers a wide selection of refurbished laboratory equipment to support molecular biology, biotechnology, pharmaceutical research, and analytical laboratory workflows.
QSonica Q500 Ultrasonic Homogenizer Frequently Asked Questions
What components are included with this system?
This system includes the QSonica Q500 ultrasonic generator, the CL-334 converter with direct sonication probe, and the QSonica sound enclosure, providing a complete ultrasonic processing workstation ready for laboratory installation.
What is the purpose of the sound enclosure?
The sound enclosure reduces operating noise by approximately 20 dBA while securely supporting the converter and probe assembly, improving operator comfort during extended sonication procedures.
What sample volumes can the included probe process?
The included standard probe is well suited for routine laboratory processing of medium-volume samples. Actual working volumes depend on the probe installed and the application. Additional probe sizes are available for both smaller and larger sample volumes.
What laboratory applications is the Q500 commonly used for?
The Q500 is widely used for cell lysis, tissue homogenization, nanoparticle dispersion, emulsification, protein extraction, DNA and RNA preparation, pharmaceutical formulation, and many other ultrasonic sample preparation applications.
What warranty is included?
This refurbished QSonica Q500 Ultrasonic Homogenizer with CL-334 Converter, Probe, and Sound Enclosure includes a 90-day warranty from American Instrument Exchange.
