AirClean Systems AC648LFUVC 48" PCR Workstation – Used & Refurbished
Refurbished AirClean AC648LFUVC PCR Workstation for Sale
The AirClean Systems AC648LFUVC is a 48-inch combination PCR workstation designed to provide an ISO Class 5 (Class 100) clean-air environment for polymerase chain reaction (PCR) preparation, molecular biology research, DNA and RNA handling, and other contamination-sensitive laboratory procedures. Combining HEPA-filtered vertical laminar airflow with timed UV-C irradiation, the AC648LFUVC helps laboratories reduce airborne particulate contamination and minimize the risk of sample carryover during sensitive molecular biology workflows.
Part of AirClean Systems' AC600 Series, the AC648LFUVC incorporates a UVTect microprocessor controller that monitors HEPA filtration and UV lamp effectiveness while providing variable-speed blower control, programmable UV exposure, and a laboratory event timer.
The workstation features a spacious 47-inch-wide interior, making it particularly useful for laboratories performing higher-throughput PCR preparation or working with multiple reagent racks, pipettes, sample tubes, and microplates. Its transparent polycarbonate enclosure provides excellent visibility, while the folding front sash allows convenient access to the work chamber.
Unlike a conventional biological safety cabinet, the AC648LFUVC is designed primarily to protect samples from contamination. It is not intended to provide personnel protection from infectious biological aerosols or hazardous chemical vapors.
American Instrument Exchange offers this AirClean Systems AC648LFUVC, SKU 1697C CL BENCH, as a professionally refurbished PCR workstation. The unit is inspected, cleaned, refurbished, and tested prior to shipment. Unless otherwise specified, new HEPA filters are installed during refurbishment.
A 90-day warranty is included from American Instrument Exchange.
Key Features
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AirClean Systems AC648LFUVC combination PCR workstation
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48-inch nominal exterior width
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Approximately 47-inch interior working width
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ISO Class 5 (Class 100) vertical laminar airflow
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HEPA-filtered clean-air environment
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UVTect microprocessor controller
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254 nm UV-C germicidal irradiation
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Programmable UV timer, up to 59 minutes
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Continuous HEPA filter monitoring
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UV lamp effectiveness monitoring
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Variable-speed blower control
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Laboratory event timer
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Transparent polycarbonate enclosure
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Chemical-resistant polypropylene construction
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Full-access folding front sash
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Automatic UV shutoff when the sash is opened
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UV shelf with integrated pipette holder
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Electrical cord access port
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Audible and visual low-airflow alarm
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Ductless, benchtop operation
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Refurbished and tested by American Instrument Exchange
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90-day warranty included
Overview
The AirClean Systems AC648LFUVC is designed for laboratories where preventing contamination during PCR setup is essential to obtaining accurate and reproducible experimental results.
PCR amplification is extremely sensitive to contamination. Small quantities of previously amplified DNA, environmental nucleic acids, or material transferred between samples can interfere with reactions and produce false-positive results.
The AC648LFUVC addresses these challenges through a combination of HEPA-filtered vertical airflow and timed UV-C treatment.
During operation, room air passes through electrostatic prefiltration and HEPA filtration before entering the work chamber as clean vertical airflow. This helps reduce airborne particulate contamination around PCR reagents, pipettes, tubes, and other materials.
Between procedures, the integrated UV-C lamp can be operated with the sash closed to provide supplementary treatment of exposed interior surfaces.
The UVTect controller continuously monitors filtration and UV lamp condition, helping operators recognize when maintenance may be required.
The result is a dedicated PCR preparation workstation that combines clean airflow, UV-C treatment, intelligent monitoring, and a large working area in a single benchtop instrument.
Why Choose the AirClean AC648LFUVC?
The AC648LFUVC is particularly well suited to laboratories requiring more working space than a conventional 24- or 32-inch PCR workstation can provide.
Its approximately 47-inch-wide interior accommodates multiple pipette racks, reagent containers, sample tubes, PCR plates, and other materials while allowing researchers to maintain organized preparation areas.
This can be especially useful for laboratories performing high-throughput PCR setup, molecular diagnostics, genetic analysis, forensic testing, or sequencing-library preparation.
The combination of HEPA-filtered airflow and UV-C treatment provides two complementary approaches to contamination control.
HEPA filtration helps reduce airborne particles during active procedures, while timed UV-C exposure can provide supplementary surface decontamination between preparation sessions.
The UVTect controller adds continuous monitoring and operating controls that distinguish the AC648LFUVC from basic PCR enclosures.
For laboratories seeking a large, dedicated clean-air PCR preparation workstation, the AC648LFUVC offers an excellent combination of workspace, contamination-control features, and convenience.
HEPA-Filtered ISO Class 5 Vertical Laminar Airflow
One of the defining features of the AC648LFUVC is its ISO Class 5 vertical laminar airflow system.
Room air enters the workstation through electrostatic prefiltration before passing through the HEPA filtration system. Clean air then moves vertically downward into the working chamber.
This airflow helps minimize airborne particulate contamination during procedures involving PCR reagents, nucleic acid samples, microcentrifuge tubes, and amplification plates.
The 48-inch model uses two HEPA filters in its standard filtration configuration, providing clean-air coverage across the larger working area.
The UVTect controller continuously monitors filtration condition and includes variable-speed blower control.
Maintaining a clean-air environment is especially important during pre-amplification procedures, where contamination introduced during reagent preparation can affect subsequent PCR results.
Proper workstation operation, filter maintenance, cleaning, and laboratory technique remain essential to contamination control.
UV-C Germicidal Irradiation & PCR Contamination Control
The AirClean AC648LFUVC incorporates a 254 nm UV-C lamp designed to provide supplementary surface decontamination between laboratory procedures.
UV-C irradiation can help reduce contamination on directly exposed surfaces when used with appropriate exposure times and validated laboratory procedures.
The workstation includes a programmable UV timer that allows operators to select treatment intervals of up to 59 minutes.
The enclosure's polycarbonate and polypropylene construction is designed to reflect UV energy within the chamber, helping support UV exposure of interior surfaces.
An automatic safety interlock switches off the UV lamp when the front sash is opened, helping prevent accidental operator exposure.
For PCR laboratories, timed UV-C treatment can be particularly useful between reagent preparation sessions and following procedures where carryover contamination is a concern.
UV-C irradiation should not be treated as a replacement for routine cleaning or appropriate chemical decontamination. Effectiveness depends on lamp condition, exposure time, surface cleanliness, and whether contaminated areas receive adequate UV exposure.
UVTect Microprocessor Controller
The AC648LFUVC incorporates AirClean Systems' UVTect microprocessor controller, which provides operating controls and continuous monitoring of important workstation functions.
The controller monitors HEPA filter condition and UV lamp effectiveness, helping operators recognize when maintenance or component replacement may be required.
Variable-speed blower control allows airflow to be adjusted for appropriate laboratory procedures, while the digital UV timer supports repeatable UV exposure cycles.
A separate laboratory event timer provides additional convenience during timed preparation procedures.
The system also incorporates audible and visual alerts for low-airflow conditions.
These features are particularly useful in laboratories where PCR preparation is performed frequently and maintaining consistent workstation operation is important.
Large 48-Inch PCR Preparation Workspace
The AC648LFUVC provides a substantial working area while maintaining a relatively compact benchtop footprint.
With approximately 47 inches of interior width and 23 inches of interior depth, the workstation accommodates multiple racks, pipettes, reagent containers, and PCR preparation materials.
This additional space can be valuable for laboratories preparing large numbers of reactions or processing multiple samples simultaneously.
The larger chamber also provides flexibility for organizing dedicated work zones, helping researchers separate clean reagents, active preparation materials, and waste.
Even with the additional space, the workstation should not be overcrowded. Materials should be positioned to avoid interfering with the intended clean-air pattern.
For laboratories with high PCR preparation volumes, the larger workspace can improve organization and reduce the need to repeatedly move materials into and out of the enclosure.
Polycarbonate & Polypropylene Construction
The AC648LFUVC incorporates transparent polycarbonate panels and polypropylene construction designed for laboratory use.
The clear enclosure provides excellent visibility of the working chamber, while the seamless plastic design helps minimize joints and gaps where contamination or residues might accumulate.
The polypropylene base provides a chemically resistant working surface suitable for many routine molecular biology procedures.
The enclosure is also designed to support UV-C treatment within the chamber.
These construction features make the AC648LFUVC particularly useful in laboratories requiring frequent cleaning and organized sample preparation.
Cleaning agents should be selected according to AirClean Systems' recommendations to avoid damaging the polycarbonate or polypropylene components.
Integrated Pipette Holder & Utility Access
The AC648LFUVC includes a UV shelf with an integrated pipette holder, providing a convenient location for compatible pipettes within the workstation.
Maintaining dedicated PCR pipettes inside a pre-amplification preparation area can help reduce contamination associated with transferring equipment between laboratory work zones.
The workstation also incorporates an access port for electrical cords, allowing certain compatible instruments to be operated inside the enclosure when appropriate.
These features support an organized PCR preparation workflow and help laboratories establish consistent operating procedures.
AirClean AC648LFUVC vs. AC632LFUVC
The AirClean AC648LFUVC and AC632LFUVC are closely related combination PCR workstations that share the same basic contamination-control technologies.
Both incorporate ISO Class 5 HEPA-filtered vertical airflow, UV-C irradiation, UVTect monitoring, programmable UV timers, and transparent enclosures.
The primary difference is workspace size.
The AC632LFUVC is a 32-inch workstation with approximately 31 inches of interior width, while the AC648LFUVC is a 48-inch workstation with approximately 47 inches of interior width.
The AC648LFUVC is therefore better suited to laboratories requiring more room for sample racks, reagents, PCR plates, or multiple preparation activities.
The AC632LFUVC may be preferable for laboratories with limited benchtop space or lower sample volumes.
AirClean AC648LFUVC vs. AC648TLFUVC
The AC648LFUVC and AC648TLFUVC share the same nominal 48-inch width and combination HEPA/UV-C contamination-control approach.
The primary difference is chamber height.
The standard AC648LFUVC measures approximately 30 inches high externally, while the taller AC648TLFUVC measures approximately 41 inches high.
The taller model provides additional interior clearance for larger equipment and specialized workflows.
For routine PCR preparation involving pipettes, reagent racks, microcentrifuge tubes, and amplification plates, the standard AC648LFUVC provides a spacious and practical working environment.
PCR Workstation vs. Biosafety Cabinet
Although PCR workstations and biological safety cabinets can appear similar, they are designed for different purposes.
The AC648LFUVC is intended to protect samples and reagents from contamination through HEPA-filtered clean airflow and supplementary UV-C treatment.
A Class II biological safety cabinet, by comparison, is designed to provide personnel, product, and environmental protection during appropriate procedures involving biological hazards.
The AC648LFUVC does not provide the personnel containment required for handling infectious biological aerosols.
Laboratories should select equipment based on the materials being handled, the procedures performed, and the applicable risk assessment.
Common Applications
The AirClean AC648LFUVC is well suited to PCR master mix preparation, reagent aliquoting, DNA and RNA sample preparation, quantitative PCR (qPCR) setup, reverse-transcription PCR (RT-PCR) preparation, molecular biology research, genetic analysis, sequencing-library preparation, forensic DNA testing, environmental DNA analysis, and other contamination-sensitive procedures.
Its large 48-inch workspace makes it especially attractive for laboratories performing high-throughput PCR preparation or processing multiple sample batches.
Ideal Laboratory Environments
The AC648LFUVC is an excellent choice for molecular biology laboratories, biotechnology companies, pharmaceutical research facilities, genetic testing laboratories, clinical molecular laboratories, forensic laboratories, university research departments, environmental testing facilities, and contract research organizations.
Its combination of HEPA-filtered airflow, UV-C treatment, UVTect monitoring, and generous working space makes it particularly useful for facilities seeking a dedicated pre-amplification PCR preparation area.
Key Specifications
| Specification |
Details |
| Manufacturer |
AirClean Systems |
| Model |
AC648LFUVC |
| Series |
AC600 |
| Equipment Type |
Combination PCR Workstation |
| Condition |
Used and Refurbished |
| AIE SKU |
1697C CL BENCH |
| Nominal Width |
48" |
| Exterior Dimensions |
Approximately 48" W × 24" D × 30" H |
| Interior Dimensions |
Approximately 47" W × 23" D × 21" H |
| Airflow Configuration |
Vertical Laminar Flow |
| Clean-Air Classification |
ISO Class 5 / Class 100 |
| Primary Filtration |
Two HEPA Filters |
| Prefiltration |
Electrostatic |
| Controller |
UVTect Microprocessor |
| UV Lamp |
254 nm UV-C |
| UV Timer |
Programmable, 1–59 Minutes |
| HEPA Monitoring |
Continuous Filter Condition Monitoring |
| UV Monitoring |
UV Lamp Effectiveness Monitoring |
| Blower Control |
Variable Speed |
| Alarm System |
Audible and Visual Low-Airflow Alarm |
| Enclosure Construction |
Polycarbonate and Polypropylene |
| Front Access |
Folding Polycarbonate Sash |
| UV Safety |
Automatic UV Shutoff When Sash Opens |
| Additional Features |
UV Shelf, Pipette Holder, Laboratory Event Timer |
| Utility Access |
Electrical Cord Access Port |
| Ventilation |
Ductless / Recirculating |
| Electrical |
115V, 60 Hz on AIE Listing |
| Installation |
Benchtop |
| Warranty |
90 Days from American Instrument Exchange |
Specifications are based on AirClean Systems manufacturer information and the American Instrument Exchange listing. Exact installed components, electrical nameplate information, and filtration condition should be confirmed for the individual refurbished unit.
Refurbishment & Testing
American Instrument Exchange specializes in professionally refurbished laboratory equipment, helping laboratories obtain dependable instruments while reducing acquisition costs.
The AirClean AC648LFUVC is inspected, cleaned, refurbished, and functionally tested prior to shipment.
The refurbishment process includes evaluation of the blower system, UVTect controller, UV lamp operation, lighting, sash safety interlock, operating alarms, enclosure condition, and HEPA filtration.
Particular attention is given to the filtration and UV systems because both contribute to the workstation's intended contamination-control functions.
Unless otherwise specified, new HEPA filters are installed during refurbishment. UV lamp condition and other consumable components are evaluated and addressed as necessary.
The refurbished AC648LFUVC includes a 90-day warranty from American Instrument Exchange.
Shipping & Installation
The AirClean AC648LFUVC is a ductless benchtop PCR workstation that does not require connection to an external exhaust system.
With exterior dimensions of approximately 48 inches wide, 24 inches deep, and 30 inches high, the workstation can be accommodated on a suitably sized laboratory bench.
The bench should provide stable support and adequate clearance for normal operation and maintenance.
Because the enclosure incorporates transparent polycarbonate panels and electronic components, appropriate packaging and handling are important during shipment.
After delivery, laboratories should inspect the workstation, verify proper blower and UVTect operation, confirm that safety interlocks function correctly, and establish appropriate cleaning and contamination-control procedures before routine use.
Related Laboratory Equipment
The AirClean AC648LFUVC fits naturally into molecular biology, genetic analysis, and PCR laboratory workflows.
PCR thermal cyclers, microcentrifuges, refrigerated centrifuges, vortex mixers, pipettes, and laboratory refrigerators support reagent preparation, sample processing, and amplification procedures.
Ultra-low temperature freezers provide long-term storage of sensitive biological materials, while laboratory refrigerators and freezers support temperature-sensitive reagents and supplies.
For laboratories performing procedures involving potentially hazardous biological aerosols, appropriately selected biosafety cabinets may be required in addition to the PCR workstation.
American Instrument Exchange maintains a broad inventory of used and refurbished laboratory equipment, allowing laboratories to source multiple instruments through a single supplier.
AirClean AC648LFUVC Frequently Asked Questions
What is the AirClean AC648LFUVC used for?
The AC648LFUVC is a combination PCR workstation designed for contamination-sensitive molecular biology procedures.
It is commonly used for PCR master mix preparation, reagent aliquoting, DNA and RNA sample preparation, qPCR setup, and other pre-amplification workflows.
Its HEPA-filtered vertical airflow and timed UV-C treatment help reduce contamination risks.
How large is the AirClean AC648LFUVC?
The workstation measures approximately 48 inches wide, 24 inches deep, and 30 inches high.
Its interior provides approximately 47 inches of width, 23 inches of depth, and 21 inches of height.
This makes it well suited to laboratories requiring a large PCR preparation workspace.
Does the AC648LFUVC have HEPA filtration?
Yes. The standard AC648LFUVC configuration uses two HEPA filters to provide ISO Class 5 vertical laminar airflow across the working area.
The UVTect controller monitors filter condition and alerts users when maintenance may be required.
Does the AirClean AC648LFUVC have UV-C decontamination?
Yes. The workstation incorporates a 254 nm UV-C lamp with a programmable timer.
UV-C exposure can provide supplementary surface decontamination between procedures, but it should not replace routine cleaning and appropriate chemical decontamination.
What is the UVTect controller?
UVTect is AirClean Systems' microprocessor-based monitoring and control system.
It provides HEPA filter monitoring, UV lamp effectiveness monitoring, variable-speed blower control, programmable UV timing, and other operating functions.
Is the AC648LFUVC suitable for qPCR?
Yes. The workstation is suitable for preparing qPCR reagents, master mixes, tubes, and plates.
Its clean-air environment helps reduce airborne particulate contamination during pre-amplification procedures.
Can the AC648LFUVC be used for RNA work?
Yes. The workstation can support RNA preparation and RT-PCR setup where a clean working environment is beneficial.
However, HEPA filtration and UV-C treatment do not guarantee an RNase-free environment. Appropriate RNase-control procedures remain necessary.
What is the difference between the AC648LFUVC and AC632LFUVC?
Both models incorporate HEPA-filtered vertical airflow, UV-C treatment, and UVTect monitoring.
The primary difference is width. The AC648LFUVC provides approximately 47 inches of interior width, compared with approximately 31 inches for the AC632LFUVC.
Does the AC648LFUVC require external ductwork?
No. The workstation is a ductless, recirculating clean-air enclosure.
It does not require external exhaust ductwork for its intended PCR preparation applications.
Is the AirClean AC648LFUVC a biosafety cabinet?
No. The AC648LFUVC is a PCR workstation designed primarily for sample protection.
It does not provide the personnel containment required for procedures involving hazardous biological aerosols.
Can the UV lamp operate while the sash is open?
No. The workstation incorporates a safety interlock designed to shut off UV irradiation when the sash is opened.
This helps prevent accidental operator exposure to UV-C radiation.
Can the HEPA filters be replaced?
Yes. The AC648LFUVC uses replaceable HEPA filtration.
The UVTect controller monitors filter condition and provides maintenance-related alerts.
Replacement filters should be selected according to the manufacturer's specifications.
What if the UVTect controller displays an alarm?
An alarm may indicate a filtration problem, low-airflow condition, UV lamp issue, or another monitored operating condition.
The specific alarm should be investigated before continuing contamination-sensitive procedures.
Depending on the cause, maintenance may involve filter replacement, UV lamp replacement, electrical service, or other repairs.
Is a used AirClean AC648LFUVC worth refurbishing?
In many cases, yes.
The AC648LFUVC incorporates a substantial enclosure, filtration system, blower, UVTect controller, and UV-C lighting components.
Problems involving consumable filters, UV lamps, or other serviceable components do not automatically justify replacing the entire workstation.
Repair feasibility depends on overall condition, parts availability, and the cost of restoring proper operation.
Why purchase a refurbished AirClean AC648LFUVC from American Instrument Exchange?
American Instrument Exchange specializes in used and refurbished laboratory equipment, providing research facilities with cost-effective alternatives to purchasing new instruments.
The AirClean AC648LFUVC combines a large 48-inch workspace with HEPA-filtered ISO Class 5 vertical airflow, UV-C treatment, and UVTect monitoring.
Each refurbished unit is inspected, cleaned, and functionally tested prior to shipment and includes a 90-day warranty.
For laboratories seeking a spacious PCR preparation workstation for molecular biology, genetic analysis, and contamination-sensitive sample handling, the refurbished AC648LFUVC offers an excellent combination of functionality, workspace, and value.
