Skip to content
LAB EQUIPMENT REPAIRS, INCLUDING ULTRALOW FREEZERS, FRIDGES, CENTRIFUGES AND MORE - Click here for details
LAB EQUIPMENT REPAIRS, INCLUDING ULTRALOW FREEZERS, FRIDGES, CENTRIFUGES AND MORE - Click here for details

Baker SterilSHIELD SS500 Positive-Pressure Compounding Aseptic Isolator

Fully Tested & Warrantied*
Brand : Baker
Product Code : SKU 2725B GLOVE BOX
Title: $12500.00

Shipping

All products ship from our 30,000 sq. ft. Haverhill, MA warehouse

Baker SterilSHIELD SS500 Positive-Pressure Compounding Aseptic Isolator

The Baker SterilSHIELD SS500 Compounding Aseptic Isolator is a positive-pressure, HEPA-filtered glove box designed to provide an ISO Class 5 clean environment for aseptic manipulation and compounding of non-hazardous materials. Featuring a completely enclosed main work chamber, integrated positive-pressure pass-through, vertical unidirectional HEPA-filtered airflow, stainless-steel interior, and glove-port access, the SterilSHIELD SS500 provides substantially greater separation between the operator and the clean work zone than a conventional open-front laminar flow clean bench.

Designed specifically for product protection, the SS500 maintains the main chamber at positive pressure relative to the surrounding room. HEPA-filtered air moves vertically through the work area, continuously sweeping particulate contamination away from critical materials while preventing contaminated room air from entering the enclosure during normal operation.

The SS500 also incorporates a separate positive-pressure interchange, or pass-through chamber, allowing supplies and materials to be transferred into and out of the main work zone while helping preserve clean conditions inside the isolator.

The SterilSHIELD was developed primarily for pharmacy and aseptic-processing applications involving non-hazardous compounded preparations, sterile materials, non-infectious tissue culture work, IV preparation, and other procedures where maintaining a highly controlled particle-free environment is essential.

Importantly, the Baker SterilSHIELD SS500 is not designed for personnel or environmental protection. It should not be used with hazardous drugs, infectious biological materials, toxic chemicals, volatile chemicals, radionuclides, or other substances requiring containment.

This used and reconditioned Baker SterilSHIELD SS500 from American Instrument Exchange is inspected, cleaned, functionally tested, and pressure tested before shipment. The unit includes new gloves, a hydraulic lift stand, and a 90-day warranty from American Instrument Exchange.

Baker SterilSHIELD SS500 Key Features

  • Positive-pressure compounding aseptic isolator

  • Designed for product protection

  • Provides better than ISO Class 5 / former Class 100 air cleanliness

  • Vertical unidirectional HEPA-filtered airflow

  • 99.99% efficient HEPA supply filtration at 0.3 micron

  • Positive-pressure main work chamber

  • Separate positive-pressure pass-through chamber

  • Main chamber maintained at higher positive pressure than pass-through

  • Enclosed glove-box design

  • Two ergonomic oval glove ports

  • New gloves included

  • Hinged slanted front viewscreen

  • Main chamber approximately 39"W x 22"D x 26.5"H

  • Pass-through approximately 18.5"W x 22"D x 26.5"H

  • Type 304 stainless-steel interior

  • Removable stainless-steel work trays

  • Rounded interior corners for easier cleaning

  • Front-access HEPA filter

  • Washable intake prefilter

  • StediVOLT blower control system

  • Main chamber and pass-through illumination

  • Hydraulic lift stand

  • Approximately 76"W x 35.5"D overall

  • Adjustable overall height of approximately 78.9 to 98.3 inches

  • 115V, 60 Hz, 20 A dedicated electrical circuit

  • NEMA 5-20P power connection

  • Used and reconditioned by American Instrument Exchange

  • 90-day AIE warranty

Baker SterilSHIELD SS500 Overview

The Baker SterilSHIELD SS500 was designed around a simple but important objective: maintain a highly clean internal workspace while physically separating the critical work area from the surrounding laboratory or pharmacy environment.

Unlike an open-front clean bench, the SterilSHIELD uses a closed front viewscreen with integrated gloves.

The operator therefore performs procedures without placing hands or arms directly into the internal environment.

This physical barrier helps reduce one of the most significant potential contamination sources in aseptic work—the operator.

At the same time, the SS500 continuously supplies HEPA-filtered air to the work area and maintains the interior at positive pressure relative to the room.

The combination of:

HEPA filtration

unidirectional airflow

positive pressure

glove-port isolation

and

controlled material transfer

makes the SterilSHIELD particularly useful for applications where product sterility and contamination control are critical.

Baker SterilSHIELD SS500 Key Specifications

Specification Details
Manufacturer Baker
Product Line SterilSHIELD
Model SS500
Equipment Type Positive-Pressure Compounding Aseptic Isolator
Protection Type Product Protection Only
Main Chamber Pressure Positive
Pass-Through Pressure Positive
Air Cleanliness Better than ISO Class 5 / former Class 100
Airflow Pattern Vertical Unidirectional Downflow
Supply Filtration HEPA
HEPA Efficiency 99.99% at 0.3 micron
Main Chamber Interior Approx. 39"W x 22"D x 26.5"H
Pass-Through Interior Approx. 18.5"W x 22"D x 26.5"H
AIE Listed Exterior Dimensions Approx. 76"W x 35.5"D
AIE Listed Overall Height Approx. 78.87–98.25 in.
Interior Material 16-gauge Type 304 stainless steel
Work Surface Removable stainless-steel trays
Front Access Hinged viewscreen
Glove Ports Two oval glove ports
Gloves New gloves included with AIE unit
Stand Hydraulic lift stand
Electrical 115V AC, 60 Hz, 1 phase
Required Circuit 20 A dedicated
Power Connection NEMA 5-20P
Typical Standard Unit Draw Approx. 8 A
Optional Lift Draw Approx. 2 A intermittent
Standard Cabinet Weight Approx. 760 lb. on standard stand per Baker manual
Product Protection Yes
Personnel Protection No
Environmental Protection No
Hazardous Drug Use No
Condition Used / Reconditioned
AIE Warranty 90 Days

Common Applications

The Baker SterilSHIELD SS500 is well suited for aseptic compounding of non-hazardous preparations, sterile IV preparation, pharmacy compounding, sterile product manipulation, media preparation, non-infectious tissue culture procedures, sterile component handling, pharmaceutical research, quality-control work, and other applications requiring a controlled ISO Class 5 environment without the use of hazardous materials.

Its enclosed configuration makes it particularly useful where reducing direct operator interaction with the critical work zone can improve contamination control.

Ideal Laboratory & Pharmacy Environments

The SterilSHIELD SS500 is particularly appropriate for hospital pharmacies, compounding pharmacies, pharmaceutical development laboratories, biotechnology companies, healthcare systems, university medical centers, clinical research laboratories, sterile-processing environments, pharmaceutical quality-control groups, and research facilities working with non-hazardous sterile materials.

It can also be useful in specialized research or manufacturing environments where an enclosed positive-pressure ISO Class 5 workspace is preferable to an open laminar flow clean bench.

Positive-Pressure Product Protection

The defining feature of the SterilSHIELD SS500 is its positive-pressure work environment.

The internal pressure of the main chamber is maintained above the pressure of the surrounding room.

If a small leakage path exists around a seal or opening, the pressure differential encourages clean air to move outward rather than contaminated room air moving inward.

This pressure relationship supports the primary purpose of the SS500:

protecting the material inside the cabinet from environmental contamination.

The design is fundamentally different from a negative-pressure containment isolator used to protect personnel from hazardous materials.

Main Chamber & Pass-Through Pressure Cascade

The SS500 incorporates two controlled spaces:

The main work chamber

and

the pass-through chamber

Both operate at positive pressure.

However, Baker designed the main chamber to operate at a higher positive pressure than the pass-through.

When the interior pass-through door is opened, clean HEPA-filtered air therefore tends to move from the main work chamber into the pass-through rather than allowing less-controlled air to migrate toward the critical work zone.

This pressure cascade helps preserve clean conditions during material transfer.

Vertical Unidirectional HEPA-Filtered Airflow

The SterilSHIELD SS500 uses vertical unidirectional airflow rather than the horizontal airflow found in many conventional clean benches.

Room air is drawn into the system and moved into a positive-pressure supply plenum.

The air then passes through the HEPA filter and stainless-steel diffuser before entering the main chamber.

Filtered air travels downward across the work zone.

The full-ceiling supply configuration distributes clean air across the working area and continuously sweeps airborne particles toward the return-air system.

A portion of the air is recirculated while another portion is exhausted back into the laboratory.

Better Than ISO Class 5 Air Cleanliness

Baker specifies that the SterilSHIELD provides better than ISO Class 5 air cleanliness conditions inside the enclosure.

ISO Class 5 was historically referred to as Class 100 under older cleanroom terminology.

This level of particulate control is particularly valuable when preparing sterile products because even small concentrations of environmental particles can carry microorganisms or otherwise compromise critical processes.

The SS500 establishes this clean environment locally within the isolator instead of requiring the entire surrounding room to operate at the same cleanliness classification.

99.99% Efficient HEPA Filtration

The Baker SS500 uses a scan-tested HEPA supply filter rated at approximately:

99.99% efficiency for particles 0.3 micron in diameter.

Baker also designed the filter installation so the installed HEPA filter can be tested for leaks.

The HEPA system removes particulate contamination from the incoming airflow before that air reaches the direct work area.

A separate intake prefilter removes larger airborne dust and debris before they reach the HEPA filter, helping reduce premature filter loading.

Full-Ceiling HEPA Supply

The SS500's HEPA supply system covers the working chamber from above.

This configuration allows filtered air to enter the work zone across a broad area rather than from a small localized outlet.

The result is more uniform vertical downflow across the interior.

Uniform airflow is particularly important in aseptic processing because stagnant zones and excessive turbulence can compromise contamination control.

UniPressure Supply Plenum

Baker's UniPressure supply-plenum design helps distribute air across the HEPA filter before it enters the work area.

The design also provides continuous clamping force around the filter perimeter, helping maintain a secure filter seal.

Additional gasketing around the filter frame helps isolate vibration from the blower assembly.

Together, these features are intended to improve airflow uniformity, filter sealing, and long-term serviceability.

Positive-Pressure Pass-Through Chamber

One of the most useful features of the SS500 is its integrated pass-through chamber.

The pass-through measures approximately:

18.5"W x 22"D x 26.5"H

and allows supplies, containers, instruments, and materials to be moved into or out of the isolator without opening the main front viewscreen.

The pass-through incorporates:

  • An exterior door

  • An interior door leading to the main chamber

  • Positive pressure

  • HEPA-filtered airflow

The two doors should not normally be open simultaneously during operation.

This arrangement allows materials to progress through a controlled transfer sequence while minimizing disruption to the main work environment.

Large 39-Inch-Wide Main Work Chamber

The SS500 provides a main internal chamber of approximately:

39"W x 22"D x 26.5"H

This provides substantial working space for sterile preparation while retaining a compact enough format for efficient glove-port access.

The chamber can accommodate containers, trays, pharmacy equipment, sterile components, instruments, and other materials required for aseptic procedures.

Two Oval Glove Ports

The SS500 uses two oval glove ports positioned in the front viewscreen.

The oval geometry helps operators reach different areas of the work surface while limiting the need for excessive shoulder and arm movement.

Integrated gloves maintain a physical barrier between the operator and the internal work zone.

American Instrument Exchange supplies this SS500 with new gloves.

Gloves should be inspected routinely for:

  • Tears

  • Punctures

  • Cracking

  • Deterioration

  • Improper installation

  • Loss of sealing integrity

because compromised gloves can affect the controlled internal environment.

Enclosed Barrier vs. Open Laminar Flow Bench

The SterilSHIELD SS500 and a conventional horizontal clean bench both provide clean HEPA-filtered air for product protection, but they accomplish that objective differently.

A traditional clean bench has an open front.

The SterilSHIELD uses a closed viewscreen with integrated gloves.

That barrier reduces direct exchange between the operator and the work zone.

For procedures where an enclosed work environment and controlled material transfer are desirable, the SS500 can therefore provide a higher degree of physical separation than an open clean bench.

SterilSHIELD vs. Biosafety Cabinet

The SS500 should not be confused with a Class II biosafety cabinet.

A SterilSHIELD SS500 is designed primarily for:

product protection

using a positive-pressure enclosure.

A Class II biosafety cabinet is designed to provide:

personnel protection

product protection

and

environmental protection

through controlled inward airflow, HEPA-filtered downflow, and filtered exhaust.

The positive pressure that helps the SS500 protect the product is one reason it is inappropriate for hazardous biological materials.

If a leak occurs, air tends to move from inside the isolator toward the surrounding room.

SterilSHIELD vs. Negative-Pressure Compounding Isolator

Positive- and negative-pressure isolators serve fundamentally different applications.

The Baker SterilSHIELD SS500 maintains positive pressure and is intended for non-hazardous aseptic processing.

A negative-pressure containment isolator is designed to keep potentially hazardous material inside the enclosure by maintaining internal pressure below room pressure.

If hazardous drugs or other dangerous substances are being compounded, a device specifically designed and validated for hazardous-material containment is required.

The SS500 should not be substituted for such equipment.

SterilSHIELD vs. Baker ChemoSHIELD

The distinction between Baker's SterilSHIELD and ChemoSHIELD systems is particularly important.

The SterilSHIELD uses:

Positive pressure

and prioritizes:

Protection of the product

The ChemoSHIELD family was designed around negative-pressure containment for applications requiring protection from hazardous compounds.

A buyer searching for a Baker pharmacy isolator should therefore select the system according to the risk associated with the materials being handled—not simply according to cabinet size or appearance.

Not for Hazardous Drug Compounding

The Baker SterilSHIELD SS500 should not be used for hazardous drugs.

Because the main chamber operates under positive pressure and exhausts into the laboratory, the design does not provide personnel protection from hazardous substances.

Procedures involving cytotoxic, antineoplastic, or otherwise hazardous pharmaceutical compounds require equipment specifically designed for hazardous-drug containment.

Not for Infectious Biological Materials

The SterilSHIELD SS500 should also not be used for work involving infectious biological materials.

Potentially infectious organisms, hazardous biological aerosols, and other biohazards require appropriate biological containment.

A suitable Class II biosafety cabinet or other validated containment device should be selected for these procedures.

Not a Chemical Fume Hood

The SS500's HEPA filter removes particulates, not hazardous gases or vapors.

It should therefore not be used with:

  • Volatile toxic chemicals

  • Hazardous solvent vapors

  • Flammable vapors

  • Corrosive gases

  • Chemical fumes

  • Materials generating toxic gaseous emissions

A chemical fume hood or appropriate ventilated containment system should be used for hazardous chemical procedures.

Type 304 Stainless-Steel Interior

The main work area incorporates 16-gauge Type 304 stainless steel.

Stainless steel provides a durable, corrosion-resistant surface suitable for repeated cleaning and disinfection.

Baker incorporates rounded interior corners that reduce crevices where particulate or residue can accumulate.

This improves accessibility during routine wipe-down and cleaning.

Removable Work Surface Trays

The stainless-steel work surface is divided into removable sections.

The trays can be removed or stacked aside to provide access to the drain pan and lower interior surfaces.

This design helps simplify thorough cleaning of areas that are normally hidden during routine operation.

For aseptic-processing equipment, accessibility for cleaning is an important aspect of maintaining contamination control.

Hinged Slanted Viewscreen

The front viewscreen is slanted by approximately 10 degrees, improving operator viewing angle and ergonomic access.

The viewscreen is hinged at the top and can be opened fully when the isolator is not operating for:

  • Initial loading

  • Equipment installation

  • Thorough cleaning

  • Maintenance

  • Removal of large components

During normal isolator operation, the viewscreen remains closed and procedures are performed through the glove ports.

Work Area Illumination

Baker specifies approximately 97 foot-candles of illumination at the main work surface.

The pass-through receives approximately 48 foot-candles.

The lighting system is mounted outside the work chamber, helping minimize unnecessary heat accumulation within the controlled area.

Adequate lighting is especially important during sterile compounding, visual inspection, aseptic transfer, labeling, and other detailed procedures.

StediVOLT Blower Control

The SS500 incorporates Baker's StediVOLT motor speed controller.

This system helps compensate for minor fluctuations in incoming electrical voltage so blower performance and airflow remain more stable.

As the HEPA filter loads over time and airflow resistance increases, the system also provides adjustment capability to help maintain appropriate performance.

Filter-Loading Capability

Baker engineered the blower system to accommodate increasing filter resistance as the HEPA filter becomes loaded with particulate.

The system can compensate for a significant increase in filter pressure drop before airflow falls outside its intended operating range.

This capability can extend useful filter life when the cabinet is properly maintained and periodically tested.

Front-Access HEPA Filter

The supply HEPA filter can be accessed from the front of the cabinet for service.

This allows a qualified technician to replace the filter without entering deeply into the primary work zone.

After HEPA filter replacement, the isolator should be appropriately tested to verify:

  • Filter integrity

  • Filter seal integrity

  • Airflow balance

  • Pressure relationships

  • Overall performance

before being returned to critical use.

Hydraulic Lift Stand

This American Instrument Exchange SS500 includes a hydraulic lift stand.

The adjustable stand allows the working height to be changed for different users and operating preferences.

The AIE unit is listed at an overall height ranging from approximately:

78.87 inches to 98.25 inches

depending on stand position.

An adjustable work height can be especially useful in facilities where multiple operators use the isolator or where procedures vary in duration.

Electrical Requirements

Baker specifies a dedicated:

115V AC, 60 Hz, 20 A, single-phase circuit

for the SS500.

The standard cabinet is equipped with a NEMA 5-20P power cord.

The standard isolator typically draws approximately 8 A, with additional electrical demand possible for accessories such as:

  • Hydraulic lift

  • Interior receptacles

  • Pressure-monitoring equipment

The individual cabinet data plate and installed options should always be verified before site preparation.

Placement & Installation

Proper placement is important for maintaining SS500 performance.

The isolator should be located away from excessive:

  • Personnel traffic

  • Doorways

  • Supply-air diffusers

  • Windows

  • Other sources of air disturbance

Baker also specifies clearance above the exhaust outlet because the cabinet returns air to the surrounding room.

A minimum overhead clearance should be maintained so cabinet exhaust is not restricted.

Compounding Aseptic Isolator Applications

The SS500 was developed as a compounding aseptic isolator, sometimes abbreviated CAI.

A CAI uses a physical barrier and controlled airflow to maintain a clean internal environment during aseptic operations.

Typical applications may include:

Non-hazardous sterile compounding
IV preparation
Sterile dose preparation
Aseptic transfer
Pharmaceutical research
Sterile component manipulation
Non-hazardous formulation work

The actual suitability of a refurbished isolator for a regulated pharmacy workflow should be evaluated according to the facility's current policies, certification requirements, applicable USP standards, and local regulatory requirements.

SterilSHIELD SS500 & USP <797>

Baker originally developed the SterilSHIELD series for pharmacy applications and describes the current SterilSHIELD platform as intended for aseptic compounding of non-hazardous drugs.

However, purchasing a SterilSHIELD SS500 does not by itself establish compliance with current USP <797> requirements.

Compliance depends on the complete installation and operating environment, including factors such as:

  • Current equipment condition

  • Installation location

  • Certification

  • Airflow performance

  • HEPA integrity

  • Pressure relationships

  • Cleaning procedures

  • Environmental monitoring

  • Operator technique

  • Facility design

  • Current institutional and regulatory requirements

Any pharmacy considering a refurbished SS500 for regulated compounding should have the proposed installation evaluated by appropriate qualified personnel.

Pressure & Performance Testing

A positive-pressure isolator relies heavily on the integrity of its enclosure and pressure-control system.

American Instrument Exchange evaluates used glove boxes and isolators for proper operation before shipment.

Testing of this SterilSHIELD SS500 includes visual inspection for:

  • Cracks

  • Damaged panels

  • Worn seals

  • Glove condition

  • Door condition

  • Gasket integrity

  • General enclosure condition

The isolator is then pressure tested to evaluate whether the chamber maintains pressure appropriately.

Pressure Decay Testing by American Instrument Exchange

For glove-box-style systems, American Instrument Exchange performs a pressure decay test as part of evaluation.

The enclosure is pressurized and monitored to determine whether pressure remains stable or falls unexpectedly.

An excessive pressure decline can indicate leakage through:

  • Gloves

  • Glove-port connections

  • Door seals

  • Gaskets

  • Panel joints

  • Access ports

  • Other enclosure components

Identified issues can then be investigated before the unit is prepared for shipment.

Refurbishment & Testing by American Instrument Exchange

In addition to pressure evaluation, American Instrument Exchange inspects major operational systems of the Baker SterilSHIELD SS500.

Testing may include:

  • Blower operation

  • Airflow

  • Pressure indication

  • HEPA filtration condition

  • Pass-through function

  • Doors and seals

  • Glove ports

  • Control system

  • Lighting

  • Hydraulic lift

  • Electrical components

  • Power cord

  • Work surfaces

  • General cabinet condition

The unit is cleaned and prepared for laboratory use before shipment.

If a customer has specific acceptance or testing requirements, American Instrument Exchange can discuss those requirements prior to shipment.

New Gloves Included

Gloves are a critical component of an isolator system because they form part of the physical barrier separating the operator from the internal work area.

This American Instrument Exchange SS500 is supplied with new gloves.

Routine inspection remains important throughout operation.

Gloves should be replaced if they show evidence of puncture, cracking, degradation, loss of elasticity, or compromised attachment to the glove port.

On-Site Performance Verification

Baker recommends that certain performance checks be performed by qualified personnel after the isolator is installed.

These can include:

  • HEPA filter leak testing

  • Airflow verification

  • Pressure verification

  • Air balance evaluation

  • General system performance

This is particularly important after shipping because movement of a large cabinet can potentially affect components or adjustments.

For critical aseptic applications, the SS500 should be appropriately evaluated after installation before being placed into service.

Refurbished Baker Isolators from American Instrument Exchange

A refurbished Baker SterilSHIELD SS500 can provide laboratories and pharmacies with a high-quality, enclosed ISO Class 5 aseptic workspace at substantially lower cost than purchasing a new isolator.

American Instrument Exchange supplies refurbished:

  • Glove boxes

  • Compounding isolators

  • Laminar flow clean benches

  • Biosafety cabinets

  • Chemical fume hoods

  • Hypoxia workstations

  • Incubators

  • Centrifuges

  • Refrigerators

  • Freezers

  • Other laboratory equipment

Equipment is inspected, cleaned, and tested before shipment and is backed by American Instrument Exchange's warranty.

Shipping & Installation Considerations

The Baker SterilSHIELD SS500 is a large and heavy floor-standing isolator.

The AIE unit measures approximately:

76"W x 35.5"D

with an adjustable overall height of approximately:

78.87 to 98.25 inches

depending on the hydraulic lift position.

Baker documentation lists approximately 760 lb. for the SS500 cabinet on a standard tube stand, although actual weight may vary with installed accessories and the hydraulic lift configuration.

Before shipment, laboratories should evaluate:

  • Loading dock access

  • Doorway dimensions

  • Hallway clearance

  • Elevator dimensions and weight capacity

  • Final room clearance

  • Ceiling height

  • Electrical availability

  • Floor loading

  • Required service access

Large isolators should be handled using equipment appropriate to their size and weight.

Related Laboratory Equipment

Facilities considering the Baker SterilSHIELD SS500 may also require glove boxes, horizontal laminar flow clean benches, Class II biosafety cabinets, chemical fume hoods, pharmacy refrigerators, laboratory freezers, ultra-low freezers, incubators, centrifuges, and other clean-air or sample-processing equipment.

American Instrument Exchange supplies used and refurbished laboratory equipment for pharmaceutical, biotechnology, healthcare, research, clinical, academic, and industrial environments.

Baker SterilSHIELD SS500 Frequently Asked Questions

What is the Baker SterilSHIELD SS500?

The SterilSHIELD SS500 is a positive-pressure compounding aseptic isolator designed to protect non-hazardous products from contamination.

Is the SterilSHIELD SS500 a glove box?

Yes. The SS500 uses an enclosed work chamber with integrated gloves, making it a specialized clean-air glove-box or barrier-isolator system.

What air cleanliness does the SS500 provide?

Baker specifies better than ISO Class 5 air cleanliness inside the main chamber and pass-through.

Is ISO Class 5 the same as Class 100?

Class 100 is an older terminology historically associated with the cleanliness level now generally described as ISO Class 5.

What type of HEPA filter does the SS500 use?

The SS500 uses a scan-tested supply HEPA filter rated at approximately 99.99% efficiency for particles 0.3 micron in size.

Does the SterilSHIELD operate under positive or negative pressure?

The SS500 operates under positive pressure.

Why does the SS500 use positive pressure?

Positive pressure helps prevent contaminated room air from entering the work chamber, providing enhanced protection for sterile products and materials inside the isolator.

Does the pass-through also operate under positive pressure?

Yes. Both the main work area and pass-through operate at positive pressure, with the main chamber maintained at a higher pressure than the pass-through.

What is the SS500 main chamber size?

The main chamber measures approximately 39"W x 22"D x 26.5"H.

What is the pass-through size?

The pass-through measures approximately 18.5"W x 22"D x 26.5"H.

How many glove ports does the SS500 have?

The SS500 has two oval glove ports in the main front viewscreen.

Are gloves included with this unit?

Yes. This American Instrument Exchange SS500 includes new gloves.

Does the SS500 protect the operator?

No. Baker specifically identifies the SS500 as a product-protection-only isolator. It does not provide personnel protection from hazardous substances.

Can the SS500 be used for hazardous drugs?

No. The positive-pressure SterilSHIELD is intended for non-hazardous materials and should not be used for hazardous-drug compounding.

Can the SterilSHIELD be used with infectious organisms?

No. Hazardous or infectious biological materials require appropriate biological containment equipment.

Can the SS500 be used with volatile chemicals?

No. HEPA filters remove particulates rather than hazardous gases and vapors. The SS500 is not a chemical fume hood.

Is the SS500 a biosafety cabinet?

No. A biosafety cabinet is designed to provide personnel, product, and environmental protection for appropriate biological work. The SS500 provides product protection only.

What is the difference between SterilSHIELD and ChemoSHIELD?

The SterilSHIELD uses positive pressure for product protection and non-hazardous aseptic work. Baker's ChemoSHIELD family was designed around negative-pressure containment for applications involving hazardous compounds.

Can the SS500 be used for pharmacy compounding?

Yes, it was designed for aseptic compounding of non-hazardous pharmaceutical preparations. Suitability for a specific contemporary regulated pharmacy installation should be evaluated against current facility, certification, and regulatory requirements.

Is the SterilSHIELD SS500 automatically USP <797> compliant?

No single piece of equipment makes an installation compliant by itself. The SS500 was designed for aseptic pharmacy compounding, but current compliance depends on the equipment condition, installation, certification, surrounding environment, procedures, monitoring, and applicable regulations.

Does the SS500 have a pass-through chamber?

Yes. The integrated positive-pressure pass-through allows materials to enter and leave the isolator while minimizing disruption of the main clean work area.

What electrical service is required?

Baker specifies a 115V AC, 60 Hz, 20 A dedicated circuit with a NEMA 5-20P connection.

Does this SS500 have an adjustable stand?

Yes. The American Instrument Exchange unit includes a hydraulic lift stand.

What are the exterior dimensions?

American Instrument Exchange lists this unit at approximately 76"W x 35.5"D, with an adjustable overall height of approximately 78.87 to 98.25 inches.

How much does the SS500 weigh?

Baker's SS500 operator manual lists approximately 760 lb. with the standard tube stand. Weight of the specific AIE unit may differ because it is equipped with a hydraulic lift stand and other options.

How does American Instrument Exchange test this isolator?

American Instrument Exchange inspects the isolator for physical condition, seals, gloves, electrical and mechanical operation, and performs a pressure decay test to evaluate enclosure integrity. Additional testing requirements can be discussed before shipment.

What warranty is included?

This used and reconditioned Baker SterilSHIELD SS500 includes a 90-day warranty from American Instrument Exchange.

Testing Procedures for Used and Refurbished Laboratory Equipment

Ensure Accuracy, Safety, and Dependable Performance Across Applications

At American Instrument Exchange, all used and refurbished laboratory equipment undergoes a rigorous, multi-point testing protocol to ensure optimal performance, operational safety, and long-term reliability. Whether the equipment is destined for research, diagnostics, quality control, or production environments, our thorough inspection and testing process is designed to meet the highest standards of laboratory excellence.

Why Testing Used Lab Equipment Is Essential

Before any refurbished laboratory equipment is returned to service, it must be carefully tested to verify:

• Functional integrity and operational performance
• Setpoint accuracy and repeatability (where applicable)
• User interface responsiveness and control features

Proper testing reduces the risk of equipment failure, measurement inaccuracies, or user hazards—helping to ensure consistent results in clinical, academic, biotech, and industrial labs.

Our standardized lab equipment testing procedures are tailored to each equipment type, ensuring every unit meets manufacturer specifications and industry benchmarks.

Key Testing Procedures for Refurbished and Used Laboratory Equipment

1. Initial Visual Inspection

• Examine equipment housing for signs of wear, corrosion, or damage
• Check ports, power cords, and exterior components for tampering or deterioration
• Verify that internal and external parts (racks, shelves, connectors, accessories) are present and undamaged

2. Functional Startup and Operational Testing

• Power on the equipment and verify startup diagnostics
• Confirm functionality of displays, buttons, switches, and control panels
• Run basic functions to confirm proper response and behavior under standard operating conditions

3. Testing and Performance Verification

• Test internal sensors or control systems using industry-standard tools
• Perform operational tests to validate accuracy and consistency
• Verify key performance specifications such as temperature control, timing, speed, or measurement outputs, depending on equipment type

4. Mechanical and Electrical System Testing

• Evaluate motors, pumps, fans, or other moving parts for smooth operation
• Inspect and test wiring, relays, fuses, and circuit boards for safety and reliability
• Test power delivery and grounding compliance

5. Safety and Compliance Checks

• Ensure equipment is grounded and insulated to meet laboratory safety standards
• Test alarms, interlocks, emergency stops, or safety shutdown systems if applicable

6. Final Quality Assurance and Documentation

• Perform extended runtime testing
• Document operational logs, testing results, and any repairs or adjustments made
• Complete a final inspection, thorough cleaning, and packaging for delivery

Trusted Quality from American Instrument Exchange

With over 50 years of experience in laboratory equipment refurbishment, American Instrument Exchange is committed to delivering certified, lab-ready instruments backed by expert testing. Our testing protocols ensure that each piece of equipment—regardless of type—is safe, accurate, and dependable from day one.

Whether you're equipping a startup lab or expanding a high-throughput facility, you can count on our refurbished laboratory equipment to perform with precision and reliability.

Refurbishment Protocol for Used Laboratory Equipment from American Instrument Exchange

At American Instrument Exchange, every piece of used laboratory equipment we offer undergoes a multi-step refurbishment process. Whether it's an analytical balance, centrifuge, freezer, oven, or any other essential lab instrument, our goal is to restore each unit to peak performance—ensuring accuracy, safety, and long-term reliability in scientific, clinical, industrial, and academic environments.

Why Choose Refurbished Lab Equipment from American Instrument Exchange?

• Thoroughly tested for performance, precision, and safety
• Backed by a warranty
• A cost-effective alternative to new equipment
• Environmentally sustainable through equipment reuse and waste reduction
• Serviced by expert technicians with decades of laboratory equipment experience

Step-by-Step Refurbishment Protocol

Every instrument and system refurbished at American Instrument Exchange follows a detailed, industry-aligned process:

1. Initial Intake & Inspection

• Complete visual and structural inspection for cosmetic damage, wear, or corrosion
• Mechanical assessment of hinges, seals, fasteners, motors, and moving parts
• Missing components and damaged items are documented for repair or replacement

2. Cleaning and Decontamination

• Full internal and external cleaning using non-abrasive, lab-safe solutions
• Removal of biological, chemical, or particulate contamination
• Disassembly and cleaning of removable parts such as trays, shelves, and filters

3. Mechanical and Electrical Repair

• Replacement or repair of worn or broken mechanical parts
• Evaluation and servicing of control panels, sensors, switches, and displays
• Testing and repair of electrical wiring, fuses, circuit boards, and power supplies

4. Functional System Testing

• Assessment of all major functions specific to the equipment type (e.g., speed, temperature, force, weight, timing)
• Operation of control interfaces, programming menus, and digital displays
• Verification of stabilization time, responsiveness, and user input reliability

5. Testing and Performance Verification

• Testing of internal sensors, controllers, and measurement systems using certified tools
• Multi-point testing to ensure repeatability, accuracy, and performance consistency
• Confirmation of user-defined setpoints, timing sequences, or programmable cycles

6. Safety and Compliance Checks

• Testing of safety interlocks, alarms, and over-limit protection systems (as applicable)
• Electrical safety inspections, including grounding and insulation verification

7. Final Quality Assurance and Documentation

• Full operational testing under simulated lab conditions
• Completion of performance benchmarks, testing  results, and repair logs
• Final cleaning and visual inspection

Trust the Experts at American Instrument Exchange

With over 50 years of experience in the laboratory equipment industry, American Instrument Exchange is a trusted leader in high-quality refurbished lab instruments. Our refurbishment protocols ensure that every piece of equipment we sell is lab-ready—offering the precision, performance, and durability your team can count on.

Whether you’re outfitting a new lab or expanding an existing operation, choose American Instrument Exchange for tested, warrantied, and cost-effective laboratory equipment.

Warranty Information

All used equipment sold by American Instrument Exchange is refurbished/reconditioned, tested to meet specifications, cleaned, and comes with a 90-day warranty from the date of shipment unless otherwise specified. New products include a warranty from the manufacturer. Your warranty is only valid if you have paid your invoice. If your invoice is over 30 days old, warranty work will not be performed until your invoice is paid in full.  American Instrument Exchange is not liable for any special or consequential damages that result from the use of, or the inability to use, the materials on this site or the performance of the products,

Exceptions include international sales and items that are agreed to be sold with a lesser warranty or items that are agreed to be sold “as is.”

Should there be visible shipping damage to packaging or concealed shipping damage to item(s) supplied, buyer must communicate such damage to the delivering entity or carrier upon receipt first and to American Instrument the same day item is accepted / signed for. Failure to do so voids warranty. Customer decision to involve / procure third party or OEM service other than American Instrument or AIE assigned vendors to resolve in-warranty instrument failure or defect without first placing a service call to American Instrument voids warranty.

Return & Cancellation Policy

American Instrument Exchange will authorize the return of and issue a full refund for any equipment that is not working as represented and could not be replaced or repaired to the customer’s satisfaction by AIE or a representative of AIE during the warranty period. Returns without prior authorization and an RMA number will not be accepted. 

Customers are responsible for proper packaging of the equipment and all included accessories. American Instrument will pay for insurance and shipping costs. Non-inventory items bought specifically to fill customer orders may possibly be returned, but on a case by case basis.

Customers who cancel orders after refurbishing has begun or after delivery where there are no equipment performance issues may be subject to a Restocking/Cancellation Fee of 20% or more and responsible for shipping costs for both the delivery and return.

Ongoing and Extended Support Options

American Instrument Exchange is able to provide additional repair and support services outside the warranty terms for most products that sell.

For biosafety cabinets, clean benches, chemical fume hoods, and other clean air products our team at AIE Laboratory Services can provide certifications, repairs, decontaminations, and other services for customers throughout New England, and guidance and limited technical assistance for any customers in the US and Canada for new or refurbished biosafety cabinets purchased from American Instrument Exchange.

For all other products, the repair service team at American Instrument Exchange can provide both field and depot repair evaluations. We can easily schedule and coordinate the pick-up and transportation of your malfunctioning equipment. By offering hourly rates lower than most OEM service providers and eliminating travel time for technicians, we help reduce repair costs. Furthermore, our lab depot repair service minimizes or eliminates scheduling delays. Our experienced service technicians are qualified to restore your equipment to factory specifications.

Please contact our team at info@americaninstrument.com for more details.

FAQ

Does the equipment come with a warranty?

Yes, all equipment from American Instrument Exchange comes with a warranty.
Used/reconditioned/refurbished equipment is tested to make sure it operates to the manufacturer's specifications and comes with a 90-day warranty (unless otherwise noted). New equipment comes with a warranty from the manufacturer.

How do you test and recondition the equipment?

Testing requirements vary across all the equipment categories we sell. Temperature controlled units are tested with NIST traceable probes and data loggers. Gaskets, external housing, glass, handles, controls and control screens are all thoroughly inspected for integrity and functionality.
We test all equipment using the manufacturer's parameters and specifications to confirm that the unit operates properly.

How do products ship from American Instrument Exchange?

We can ship products both nationally and internationally using a well-established network of transporters. Smaller items will ship via UPS. Larger equipment will be palletized and shipped either LTL or air-ride, depending on the specific equipment and/or delivery requirements.

Return and order cancellation policy

American Instrument Exchange will accept the return of any product that is not working as represented and could not be replaced or repaired to the customer's satisfaction during the warranty period. Customers who cancel orders after refurbishing has begun will be subject to a cancellation and restocking fee of between 20% and 40%.

Are discounts available for educational or non-profit institutions, or for bulk purchases?

Yes – call or email us today with a list of equipment you're looking for and we can potentially put together a quote that includes a discount.

How does your price matching policy work?

We strive to keep our pricing competitive and reasonable. If you find comparable items for sale at a lower price from other vendors please send us a link and or quote for the item and we'll do our best to match or beat the price.

Can I see the equipment in person before committing to a purchase?

Customers are welcome to make an appointment to view equipment in our warehouse. Given our workload we may not be able to test or clean the equipment prior to your arrival if you have not committed to an order.

1023 Western Avenue is a working warehouse, not a showroom, and customers should dress appropriately and wear closed toe shoes.

Can I ship products that I purchased elsewhere to American Instrument for repair?

Yes – please see our repair services page for more information.