All products ship from our 30,000 sq. ft. Haverhill, MA warehouse
Caron 6545-1 Photostability Chamber
Light exposure can significantly affect the stability, potency, appearance, and shelf life of pharmaceutical products, medical devices, cosmetics, and other light-sensitive materials. The Caron 6545-1 Photostability Chamber was purpose-built to perform controlled photostability testing in accordance with ICH Q1B Option 2 guidelines, combining precisely regulated temperature, humidity, visible light, and near-ultraviolet (UVA) illumination within a single environmental chamber. Designed specifically for photostability studies, the 6545-1 provides laboratories with the repeatable testing conditions required for product development, validation, and regulatory compliance.
Featuring a 10.5 cubic foot (296-liter) chamber, the Caron 6545-1 maintains temperatures from 10°C to 35°C while controlling relative humidity from 40% to 70% RH. Independent fluorescent UVA and cool white visible light banks, calibrated light detectors, and an intuitive touchscreen controller allow users to perform both forced degradation studies and confirmatory photostability testing with exceptional accuracy and repeatability. Purchasing a refurbished Caron 6545-1 from American Instrument Exchange provides laboratories with dependable photostability testing equipment at substantial savings compared with purchasing new equipment.
Caron 6545-1 Photostability Chamber Key Features
10.5 cu. ft. (296 L) chamber capacity
Designed for ICH Q1B Option 2 photostability testing
Temperature range: 10°C to 35°C
Relative humidity range: 40% to 70% RH
Independent UVA and visible (cool white) fluorescent light banks
Typical UVA intensity of 20 W/m²
Typical visible light intensity of 20 klux
Calibrated UVA and VIS light detectors with integral radiometers
Digital color touchscreen controller
Automatic exposure-based light shutoff
Stainless steel interior with reflective aluminum surfaces
Two sliding shelves
Mechanical refrigeration with ultrasonic humidity control
90-day warranty from American Instrument Exchange
Designed for Regulatory Photostability Testing
The Caron 6545-1 was engineered specifically for laboratories evaluating the effects of light exposure on pharmaceutical formulations, biologics, medical devices, cosmetics, packaging materials, and other light-sensitive products. Its 296-liter chamber provides ample space for multiple sample sets while maintaining highly uniform illumination and tightly controlled environmental conditions throughout the testing cycle.
Unlike conventional environmental chambers fitted with light sources, the 6545-1 was purpose-built for photostability testing. Separate UVA and visible light banks can be operated independently or together, while calibrated light sensors continuously monitor cumulative exposure. The chamber can automatically terminate a test once the programmed light dose or exposure time has been achieved, improving repeatability and reducing operator intervention.
Common Applications
The Caron 6545-1 Photostability Chamber is commonly used for:
The Caron 6545-1 is well suited for pharmaceutical manufacturers, biotechnology companies, contract testing laboratories, universities, cosmetic manufacturers, food and beverage companies, medical device manufacturers, and quality assurance laboratories that must perform validated photostability testing under internationally recognized guidelines.
Purpose-Built for Accurate Photostability Testing
The Caron 6545-1 combines precise temperature and humidity control with calibrated UVA and visible light exposure in a single integrated platform. Mechanical refrigeration and ultrasonic humidity control maintain stable environmental conditions, while reflective interior surfaces and strategically positioned overhead lamps promote excellent light uniformity throughout the chamber. Built-in radiometers continuously monitor both UVA and visible light intensity, and programmable exposure limits automatically terminate testing once the required dose has been achieved. These features allow laboratories to perform reproducible photostability studies while supporting compliance with ICH Q1B recommendations.
Typical Samples and Photostability Testing Applications
The 296-liter (10.5 cubic foot) chamber of the Caron 6545-1 provides ample capacity for laboratories conducting photostability studies on pharmaceutical products, biologics, medical devices, cosmetics, nutraceuticals, packaging materials, and other light-sensitive products. The spacious chamber accommodates multiple sample sets simultaneously, making it well suited for product development, quality assurance, and regulatory testing environments.
The chamber includes two adjustable sliding shelves, allowing users to organize samples while maintaining uniform exposure to both visible and ultraviolet light. Samples should be arranged to minimize shading and provide consistent illumination across all test materials. Proper spacing also promotes uniform airflow and stable environmental conditions throughout extended testing protocols, helping laboratories generate accurate, repeatable results.
Energy Efficiency and Operating Costs
The Caron 6545-1 was designed for continuous laboratory operation while maintaining precise environmental conditions with efficient energy use. Its insulated cabinet, mechanical refrigeration system, and ultrasonic humidity control work together to regulate chamber conditions while minimizing temperature fluctuations during long-term studies.
Independent UVA and visible fluorescent light banks allow laboratories to operate only the lighting required for a particular protocol, helping reduce unnecessary energy consumption and extend lamp life. Integrated radiometers continuously monitor cumulative light exposure, and the chamber can automatically terminate testing once the programmed exposure has been achieved, improving laboratory efficiency while eliminating unnecessary operating time. Durable stainless steel construction and removable shelving simplify routine cleaning and preventative maintenance for years of dependable service.
Stainless Steel with Reflective Aluminum Interior Panels
Shelves Included
2 adjustable sliding shelves
Electrical Requirements
208–230 V, 60 Hz
Specifications are believed to be accurate but may vary depending on production date or factory-installed options. Please verify all specifications prior to purchase.
The Caron 6545-1 is designed specifically for ICH Q1B photostability testing of pharmaceuticals, biologics, medical devices, cosmetics, packaging materials, nutraceuticals, and other products that may be affected by light exposure.
What is ICH Q1B photostability testing?
ICH Q1B is an internationally recognized guideline that establishes standardized procedures for evaluating how exposure to visible and ultraviolet light affects pharmaceutical products and other regulated materials. The Caron 6545-1 was designed to support testing performed in accordance with these guidelines.
Why are separate UVA and visible light sources important?
Different products respond differently to ultraviolet and visible light. Independent light banks allow laboratories to perform exposure studies using UVA light, visible light, or both simultaneously while accurately measuring cumulative light exposure throughout the study.
How does the chamber ensure accurate light exposure?
Integrated radiometers continuously monitor both UVA and visible light intensity during operation. Users can program cumulative exposure limits, and the chamber automatically ends the test once the required light dose has been achieved, improving repeatability between studies.
What types of products are commonly tested?
The Caron 6545-1 is commonly used to evaluate pharmaceutical formulations, biologics, vaccines, medical devices, cosmetic products, nutraceuticals, packaging materials, food packaging, and other light-sensitive products during research, development, and quality assurance.
Is the chamber suitable for long-term stability studies?
Yes. The combination of precise temperature control, regulated humidity, calibrated light exposure, and continuous environmental monitoring makes the chamber well suited for long-duration photostability and product stability studies.
What laboratories commonly use the Caron 6545-1?
The Caron 6545-1 is widely used by pharmaceutical manufacturers, biotechnology companies, contract testing laboratories, cosmetic manufacturers, universities, food and beverage companies, medical device manufacturers, and quality assurance laboratories performing regulated stability testing.
Why purchase a refurbished Caron 6545-1 from American Instrument Exchange?
Purchasing a refurbished Caron 6545-1 from American Instrument Exchange provides laboratories with dependable photostability testing equipment at significant savings compared with purchasing new equipment. Combining a 10.5 cubic foot chamber, precise temperature and humidity control, independent UVA and visible light sources, and integrated light monitoring, the 6545-1 is an excellent solution for ICH Q1B photostability studies and other regulated environmental testing applications. Every chamber is inspected and tested prior to shipment and includes a 90-day warranty for added confidence.
Click Hereto see the Caron 6545-1 on the American Instrument Exchange YouTube channel.
Testing
Most of our equipment is used and reconditioned. Our technicians test incubators using a calibrated digital chart recorder to verify the accuracy of temperature controls and readouts. We replace any hardware or parts as is necessary and clean all incubators thoroughly prior to shipment.
Pictures
The photos above are representative. Please bear in mind that the equipment shown is currently in storage in our warehouse and that in addition to testing each machine we will clean all the equipment thoroughly prior to shipment.
We often have multiple units of each model in stock and sometimes we're unable to feature photos of every single unit. At your request, we can provide photos of the equipment in your order after testing and cleaning.
Testing Procedures for Used and Refurbished Laboratory Incubators Ensure Quality and Stability Before Use
Used and refurbished laboratory incubators from American Instrument Exchange are thoroughly tested to ensure optimal performance and temperature stability with laboratory safety standards. Each unit undergoes a detailed inspection and functionality assessment to meet the needs of research, clinical, and industrial labs.
Why Testing Used Laboratory Incubators Is Essential
Before a laboratory incubator is reintroduced into any work environment, it must be tested for:
• Temperature uniformity and accuracy
• Airflow and humidity control (if applicable)
• Door seal integrity and insulation effectiveness
• Electrical and safety system compliance
Comprehensive testing reduces the risk of culture loss, contamination, and equipment failure—especially critical in applications involving cell culture, microbiology, pharmaceutical research, and diagnostics.
Our multi-point testing protocol for used and refurbished incubators ensures reliability, safety, and performance across all models and brands.
Key Testing Procedures for Refurbished and Used Laboratory Incubators
1. Initial Visual Inspection
• Check for cosmetic damage, corrosion, and wear to exterior surfaces, door hinges, and gasket seals
• Inspect power cord, wiring, and display panel for any defects or signs of tampering
• Confirm that shelves, chamber components, and internal fixtures are present and undamaged
2. Functional Testing
• Power on the incubator and verify all display indicators and alarms function correctly
• Test door latch and seal mechanisms for proper closure and insulation
• Run basic temperature cycles to ensure the unit maintains stability over time
3. Temperature Accuracy and Uniformity Tests
• Test internal sensors and controllers using temperature probes
• Measure temperature consistency at multiple chamber locations over several hours
• Confirm that programmable temperature settings respond accurately
4. Airflow and Humidity Control (if applicable)
• Test internal fan operation and airflow distribution
• For humidified incubators, inspect and test humidity reservoirs, sensors, and control systems
• Check for condensation buildup and confirm environmental stability
5. Electrical Safety and Compliance Checks
• Ensure all electrical components are properly grounded
• Perform insulation resistance and leakage current tests
• Verify compliance with current electrical safety standards for laboratory equipment
6. Final Quality Assurance Checklist
• Perform full cycle testing at various temperature setpoints
• Document performance benchmarks and results
All refurbished incubators from American Instrument Exchange are backed by our commitment to quality and precision. With our strict testing procedures, you can rely on your incubator to deliver dependable results from day one.
Repair and Refurbishment Protocol for Used Laboratory Incubators Performance and Quality from American Instrument Exchange
At American Instrument Exchange, every used laboratory incubator we sell goes through a repair and refurbishment protocol. Whether it’s a standard, CO₂, or refrigerated incubator, our goal is to restore each unit to laboratory-level performance—ensuring temperature accuracy, environmental stability, and long-term reliability in your lab.
Why Choose a Refurbished Laboratory Incubator from American Instrument Exchange?
• Fully tested for performance and safety
• Backed by a warranty
• Cost-effective alternative to new equipment
• Environmentally sustainable through reuse and restoration
• Refurbished by expert technicians with decades of lab equipment experience
Step-by-Step Refurbishment Protocol
Every incubator at American Instrument Exchange follows this comprehensive, multi-stage process:
1. Initial Intake & Inspection
• Visual inspection for cosmetic wear, corrosion, dents, or broken components
• Mechanical assessment of door hinges, gaskets, seals, and chamber components
• Document any missing parts or issues requiring repair or replacement
2. Cleaning and Decontamination
• Thorough internal and external cleaning using non-abrasive solutions
• Decontamination/cleaning of surfaces to remove biological, chemical, or particulate residue
• Cleaning of removable parts (e.g., shelves, trays, etc.)
3. Mechanical and Electrical Repair
• Repair or replacement of worn mechanical components such as door latches, fans, hinges, and seals
• Evaluation and repair of control panels, switches, thermostats, and displays
• Inspection and testing of wiring, fuses, relays, and power supplies
4. Environmental Control System Assessment
• For CO₂ incubators: CO₂ sensors, regulators, and gas delivery systems are tested
• For refrigerated incubators: compressors, condensers, and cooling systems are evaluated for performance and leaks
• Fan motors and airflow systems are tested to ensure uniform environmental conditions
5. Temperature and Sensor Testing
• All temperature sensors and controllers are tested using thermometers/probes
• Uniformity and accuracy tested at multiple chamber locations
• For humidified or CO₂ incubators, humidity and CO₂ stability are verified
6. Safety System Testing
• Test of over-temperature protection systems and alarms
• Evaluation of door sensors, safety interlocks, and power failure recovery
7. Final Quality Control and Documentation
• Full performance test run over 24 hours
• Validation of setpoints for temperature, CO₂ (if applicable), and humidity (if applicable)
• Final inspection and cleaning before packaging
• Complete service report
Trust the Experts at American Instrument Exchange
With over 50 years in the lab equipment industry, American Instrument Exchange is a trusted source for high-quality refurbished laboratory incubators. Our proven refurbishment protocol ensures every unit is reliable, accurate, and ready to meet the demands of your lab from day one.
Warranty Information
All used equipment sold by American Instrument Exchange is refurbished/reconditioned, tested to meet specifications, cleaned, and comes with a 90-day warranty from the date of shipment unless otherwise specified. New products include a warranty from the manufacturer. Your warranty is only valid if you have paid your invoice. If your invoice is over 30 days old, warranty work will not be performed until your invoice is paid in full. American Instrument Exchange is not liable for any special or consequential damages that result from the use of, or the inability to use, the materials on this site or the performance of the products,
Exceptions include international sales and items that are agreed to be sold with a lesser warranty or items that are agreed to be sold “as is.”
Should there be visible shipping damage to packaging or concealed shipping damage to item(s) supplied, buyer must communicate such damage to the delivering entity or carrier upon receipt first and to American Instrument the same day item is accepted / signed for. Failure to do so voids warranty. Customer decision to involve / procure third party or OEM service other than American Instrument or AIE assigned vendors to resolve in-warranty instrument failure or defect without first placing a service call to American Instrument voids warranty.
Return & Cancellation Policy
American Instrument Exchange will authorize the return of and issue a full refund for any equipment that is not working as represented and could not be replaced or repaired to the customer’s satisfaction by AIE or a representative of AIE during the warranty period. Returns without prior authorization and an RMA number will not be accepted.
Customers are responsible for proper packaging of the equipment and all included accessories. American Instrument will pay for insurance and shipping costs. Non-inventory items bought specifically to fill customer orders may possibly be returned, but on a case by case basis.
Customers who cancel orders after refurbishing has begun or after delivery where there are no equipment performance issues may be subject to a Restocking/Cancellation Fee of 20% or more and responsible for shipping costs for both the delivery and return.
Ongoing and Extended Support Options
American Instrument Exchange is able to provide additional repair and support services outside the warranty terms for most products that sell.
For biosafety cabinets, clean benches, chemical fume hoods, and other clean air products our team at AIE Laboratory Services can provide certifications, repairs, decontaminations, and other services for customers throughout New England, and guidance and limited technical assistance for any customers in the US and Canada for new or refurbished biosafety cabinets purchased from American Instrument Exchange.
For all other products, the repair service team at American Instrument Exchange can provide both field and depot repair evaluations. We can easily schedule and coordinate the pick-up and transportation of your malfunctioning equipment. By offering hourly rates lower than most OEM service providers and eliminating travel time for technicians, we help reduce repair costs. Furthermore, our lab depot repair service minimizes or eliminates scheduling delays. Our experienced service technicians are qualified to restore your equipment to factory specifications.
Yes, all equipment from American Instrument Exchange comes with a warranty. Used/reconditioned/refurbished equipment is tested to make sure it operates to the manufacturer's specifications and comes with a 90-day warranty (unless otherwise noted). New equipment comes with a warranty from the manufacturer.
How do you test and recondition the equipment?
Testing requirements vary across all the equipment categories we sell. Temperature controlled units are tested with NIST traceable probes and data loggers. Gaskets, external housing, glass, handles, controls and control screens are all thoroughly inspected for integrity and functionality. We test all equipment using the manufacturer's parameters and specifications to confirm that the unit operates properly.
How do products ship from American Instrument Exchange?
We can ship products both nationally and internationally using a well-established network of transporters. Smaller items will ship via UPS. Larger equipment will be palletized and shipped either LTL or air-ride, depending on the specific equipment and/or delivery requirements.
Return and order cancellation policy
American Instrument Exchange will accept the return of any product that is not working as represented and could not be replaced or repaired to the customer's satisfaction during the warranty period. Customers who cancel orders after refurbishing has begun will be subject to a cancellation and restocking fee of between 20% and 40%.
Are discounts available for educational or non-profit institutions, or for bulk purchases?
Yes – call or email us today with a list of equipment you're looking for and we can potentially put together a quote that includes a discount.
How does your price matching policy work?
We strive to keep our pricing competitive and reasonable. If you find comparable items for sale at a lower price from other vendors please send us a link and or quote for the item and we'll do our best to match or beat the price.
Can I see the equipment in person before committing to a purchase?
Customers are welcome to make an appointment to view equipment in our warehouse. Given our workload we may not be able to test or clean the equipment prior to your arrival if you have not committed to an order.
1023 Western Avenue is a working warehouse, not a showroom, and customers should dress appropriately and wear closed toe shoes.
Can I ship products that I purchased elsewhere to American Instrument for repair?
Yes – please see our repair services page for more information.
