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Cincinnati Sub-Zero StableClimate II ST-24 Stability Chamber
Pharmaceutical, biotechnology, medical device, and quality assurance laboratories depend on controlled environmental conditions to evaluate product stability, shelf life, packaging performance, and regulatory compliance. Long-term storage studies, accelerated aging protocols, and ICH stability testing require precise control of both temperature and relative humidity to generate reliable, repeatable data. The Cincinnati Sub-Zero StableClimate II ST-24 Stability Chamber is designed specifically for these applications, providing a 24 cubic foot chamber, programmable temperature and humidity control, horizontal airflow, and a microprocessor-based control system capable of maintaining the stable environmental conditions required for regulated testing programs.
Unlike a conventional refrigerated incubator, the StableClimate II ST-24 is engineered as a dedicated stability chamber. By actively controlling both temperature and humidity, it allows laboratories to simulate storage environments used for pharmaceutical products, medical devices, packaging materials, consumer products, and other materials undergoing long-term stability evaluation. Purchasing a refurbished Cincinnati Sub-Zero StableClimate II ST-24 from American Instrument Exchange provides laboratories with a proven environmental testing platform at a substantial savings compared to purchasing a new stability chamber.
Cincinnati Sub-Zero StableClimate II ST-24 Key Features
24 cu. ft. chamber capacity
Simultaneous temperature and humidity control
Approximate temperature range: 2°C to 70°C
Approximate humidity range: 20% to 95% RH
Programmable microprocessor controller
Horizontal forced-air circulation
Compressor-based refrigeration system
Stainless steel chamber interior
Adjustable stainless steel shelving
Large insulated viewing window
Designed for continuous long-term operation
120V electrical operation (verify configuration prior to purchase)
90-day warranty from American Instrument Exchange
Designed for Stability Testing and Regulatory Compliance
The Cincinnati Sub-Zero StableClimate II ST-24 was developed specifically for laboratories performing controlled environmental testing over extended periods of time. Rather than simply maintaining a fixed incubation temperature, the chamber simultaneously regulates both temperature and relative humidity to simulate real-world storage conditions and environmental exposure. This capability makes the StableClimate II particularly valuable for pharmaceutical manufacturers, biotechnology companies, medical device developers, and quality assurance laboratories conducting stability studies under ICH guidelines and other regulated testing protocols.
Horizontal airflow distributes conditioned air evenly throughout the chamber, helping maintain uniform environmental conditions across every shelf. Combined with programmable microprocessor controls, the system allows laboratories to establish repeatable testing protocols for studies lasting weeks, months, or even years. Whether evaluating pharmaceutical formulations, validating product packaging, performing accelerated aging studies, or supporting FDA-regulated quality programs, the StableClimate II delivers the consistent environmental control required for reliable and reproducible results.
Common Applications
The Cincinnati Sub-Zero StableClimate II ST-24 is commonly used for:
ICH pharmaceutical stability studies
Long-term product stability testing
Accelerated aging studies
Shelf-life evaluation
Packaging validation
Medical device testing
Pharmaceutical quality assurance
Biotechnology product development
Environmental simulation
Regulatory compliance testing
Controlled storage studies
Product qualification testing
The StableClimate II is frequently used alongside laboratory refrigerators for reference sample storage, laboratory freezers for long-term sample preservation, HPLC systems for analytical testing, analytical balances for formulation work, and environmental chambers supporting additional qualification and validation protocols.
Ideal Laboratory Environments
The Cincinnati Sub-Zero StableClimate II ST-24 is an excellent choice for pharmaceutical manufacturers, biotechnology companies, medical device manufacturers, contract testing laboratories, food and beverage research facilities, consumer product manufacturers, packaging development laboratories, universities, and industrial quality assurance departments. Its combination of programmable temperature and humidity control makes it particularly valuable for organizations performing regulated stability studies, product validation, environmental simulation, and long-term shelf-life testing.
Why Choose the Cincinnati Sub-Zero StableClimate II ST-24?
The Cincinnati Sub-Zero StableClimate II ST-24 is purpose-built for laboratories where environmental consistency, repeatability, and regulatory compliance are critical. Its large chamber capacity, programmable environmental controls, refrigeration system, and humidity management capabilities allow researchers and quality professionals to conduct long-term stability studies with confidence.
Whether supporting pharmaceutical shelf-life testing, accelerated aging, medical device validation, packaging qualification, or environmental simulation, the StableClimate II ST-24 provides the dependable environmental control required for today's demanding research, quality assurance, and regulatory environments.
Performance and Environmental Stability
The Cincinnati Sub-Zero StableClimate II ST-24 Stability Chamber is engineered to maintain highly stable environmental conditions throughout long-term testing programs where even small fluctuations in temperature or humidity can affect product performance and study results. Its compressor-based refrigeration system, precision heating system, programmable humidity controls, and horizontal airflow work together to provide dependable environmental regulation during studies lasting weeks, months, or even years.
Unlike conventional laboratory incubators that regulate temperature alone, the StableClimate II simultaneously controls both temperature and relative humidity, allowing laboratories to recreate real-world storage environments and perform standardized stability protocols with confidence. Horizontal forced-air circulation promotes consistent temperature and humidity distribution throughout the chamber, helping ensure that samples located on different shelves experience uniform environmental exposure. This consistency is particularly important for regulated testing programs where reproducibility, documentation, and environmental control are critical.
The programmable microprocessor controller allows laboratories to establish customized testing protocols while continuously maintaining programmed environmental conditions throughout extended studies. Whether evaluating pharmaceutical formulations, medical devices, packaging materials, or consumer products, the StableClimate II provides the environmental stability required to generate reliable, repeatable data and support quality assurance and regulatory compliance programs.
Typical Samples and Laboratory Applications
The Cincinnati Sub-Zero StableClimate II ST-24 accommodates a broad range of products undergoing environmental evaluation and stability testing. Typical samples include pharmaceutical tablets and capsules, injectable medications, biologics, vaccines, diagnostic reagents, medical devices, pharmaceutical packaging, blister packs, polymers, adhesives, coatings, cosmetics, food products, beverages, consumer goods, chemical formulations, and research materials requiring controlled environmental storage.
Common laboratory applications include ICH stability studies, accelerated aging, shelf-life determination, pharmaceutical formulation development, packaging validation, environmental simulation, product qualification, medical device verification, regulatory compliance testing, quality assurance, and long-term storage studies. Its ability to independently regulate both temperature and humidity makes the StableClimate II an ideal solution for laboratories evaluating product performance under carefully controlled environmental conditions.
Cincinnati Sub-Zero StableClimate II ST-24 Specifications
Specification
Details
Manufacturer
Cincinnati Sub-Zero
Model
StableClimate II ST-24
Equipment Type
Stability Chamber
Chamber Capacity
24 cu. ft.
Temperature Range
Approximately 2°C to 70°C
Humidity Range
Approximately 20% to 95% RH
Temperature Control
Programmable Microprocessor Controller
Humidity Control
Active Humidification and Dehumidification
Air Circulation
Horizontal Forced-Air
Refrigeration System
Compressor-Based
Chamber Interior
Stainless Steel
Shelving
Adjustable Stainless Steel Shelves
Viewing Window
Insulated Glass Door
Electrical Requirements
Verify prior to purchase
Specifications are compiled from manufacturer literature and American Instrument Exchange product information. Specifications may vary depending on production year and installed options. Please verify chamber dimensions, electrical requirements, operating ranges, shelf configuration, and included accessories prior to purchase.
Frequently Asked Questions
What is a stability chamber used for?
A stability chamber is designed to maintain controlled temperature and humidity conditions for evaluating product stability, shelf life, packaging performance, and long-term environmental exposure. These chambers are widely used for pharmaceutical development, quality assurance, medical device testing, and product validation.
How is a stability chamber different from a refrigerated incubator?
A refrigerated incubator primarily regulates temperature for biological and microbiological applications. A stability chamber independently controls both temperature and relative humidity, allowing laboratories to perform pharmaceutical stability studies, accelerated aging, shelf-life testing, and environmental simulation under controlled conditions.
Can the StableClimate II ST-24 be used for ICH stability testing?
Yes. The StableClimate II product family was developed specifically for pharmaceutical stability applications commonly performed under ICH guidelines. Laboratories performing regulated studies should verify that the chamber's installed configuration satisfies the specific requirements of their testing protocol.
Why is humidity control important during stability studies?
Many pharmaceutical products, medical devices, packaging materials, and consumer products are affected by moisture exposure as well as temperature. Controlling relative humidity allows laboratories to accurately simulate storage environments and evaluate how products perform throughout their intended shelf life.
What industries commonly use stability chambers?
Stability chambers are commonly used by pharmaceutical manufacturers, biotechnology companies, medical device manufacturers, food and beverage companies, consumer product manufacturers, contract testing laboratories, packaging development organizations, universities, and industrial quality assurance departments.
Why purchase a refurbished Cincinnati Sub-Zero StableClimate II ST-24 from American Instrument Exchange?
A refurbished Cincinnati Sub-Zero StableClimate II ST-24 Stability Chamber from American Instrument Exchange provides laboratories with dependable environmental testing capability at a substantial savings compared to purchasing a new stability chamber. Featuring a 24 cubic foot chamber, programmable temperature and humidity control, horizontal forced-air circulation, a microprocessor control system, and durable laboratory construction, the StableClimate II is an outstanding choice for pharmaceutical stability studies, accelerated aging, medical device validation, packaging qualification, and long-term environmental testing. Every unit is thoroughly inspected and tested prior to shipment and includes a 90-day warranty from American Instrument Exchange.
CLICK HERE to see a video of the StableClimate II on our YouTube channel.
Testing Procedures for Used and Refurbished Laboratory Incubators Ensure Quality and Stability Before Use
Used and refurbished laboratory incubators from American Instrument Exchange are thoroughly tested to ensure optimal performance and temperature stability with laboratory safety standards. Each unit undergoes a detailed inspection and functionality assessment to meet the needs of research, clinical, and industrial labs.
Why Testing Used Laboratory Incubators Is Essential
Before a laboratory incubator is reintroduced into any work environment, it must be tested for:
• Temperature uniformity and accuracy
• Airflow and humidity control (if applicable)
• Door seal integrity and insulation effectiveness
• Electrical and safety system compliance
Comprehensive testing reduces the risk of culture loss, contamination, and equipment failure—especially critical in applications involving cell culture, microbiology, pharmaceutical research, and diagnostics.
Our multi-point testing protocol for used and refurbished incubators ensures reliability, safety, and performance across all models and brands.
Key Testing Procedures for Refurbished and Used Laboratory Incubators
1. Initial Visual Inspection
• Check for cosmetic damage, corrosion, and wear to exterior surfaces, door hinges, and gasket seals
• Inspect power cord, wiring, and display panel for any defects or signs of tampering
• Confirm that shelves, chamber components, and internal fixtures are present and undamaged
2. Functional Testing
• Power on the incubator and verify all display indicators and alarms function correctly
• Test door latch and seal mechanisms for proper closure and insulation
• Run basic temperature cycles to ensure the unit maintains stability over time
3. Temperature Accuracy and Uniformity Tests
• Test internal sensors and controllers using temperature probes
• Measure temperature consistency at multiple chamber locations over several hours
• Confirm that programmable temperature settings respond accurately
4. Airflow and Humidity Control (if applicable)
• Test internal fan operation and airflow distribution
• For humidified incubators, inspect and test humidity reservoirs, sensors, and control systems
• Check for condensation buildup and confirm environmental stability
5. Electrical Safety and Compliance Checks
• Ensure all electrical components are properly grounded
• Perform insulation resistance and leakage current tests
• Verify compliance with current electrical safety standards for laboratory equipment
6. Final Quality Assurance Checklist
• Perform full cycle testing at various temperature setpoints
• Document performance benchmarks and results
All refurbished incubators from American Instrument Exchange are backed by our commitment to quality and precision. With our strict testing procedures, you can rely on your incubator to deliver dependable results from day one.
Repair and Refurbishment Protocol for Used Laboratory Incubators Performance and Quality from American Instrument Exchange
At American Instrument Exchange, every used laboratory incubator we sell goes through a repair and refurbishment protocol. Whether it’s a standard, CO₂, or refrigerated incubator, our goal is to restore each unit to laboratory-level performance—ensuring temperature accuracy, environmental stability, and long-term reliability in your lab.
Why Choose a Refurbished Laboratory Incubator from American Instrument Exchange?
• Fully tested for performance and safety
• Backed by a warranty
• Cost-effective alternative to new equipment
• Environmentally sustainable through reuse and restoration
• Refurbished by expert technicians with decades of lab equipment experience
Step-by-Step Refurbishment Protocol
Every incubator at American Instrument Exchange follows this comprehensive, multi-stage process:
1. Initial Intake & Inspection
• Visual inspection for cosmetic wear, corrosion, dents, or broken components
• Mechanical assessment of door hinges, gaskets, seals, and chamber components
• Document any missing parts or issues requiring repair or replacement
2. Cleaning and Decontamination
• Thorough internal and external cleaning using non-abrasive solutions
• Decontamination/cleaning of surfaces to remove biological, chemical, or particulate residue
• Cleaning of removable parts (e.g., shelves, trays, etc.)
3. Mechanical and Electrical Repair
• Repair or replacement of worn mechanical components such as door latches, fans, hinges, and seals
• Evaluation and repair of control panels, switches, thermostats, and displays
• Inspection and testing of wiring, fuses, relays, and power supplies
4. Environmental Control System Assessment
• For CO₂ incubators: CO₂ sensors, regulators, and gas delivery systems are tested
• For refrigerated incubators: compressors, condensers, and cooling systems are evaluated for performance and leaks
• Fan motors and airflow systems are tested to ensure uniform environmental conditions
5. Temperature and Sensor Testing
• All temperature sensors and controllers are tested using thermometers/probes
• Uniformity and accuracy tested at multiple chamber locations
• For humidified or CO₂ incubators, humidity and CO₂ stability are verified
6. Safety System Testing
• Test of over-temperature protection systems and alarms
• Evaluation of door sensors, safety interlocks, and power failure recovery
7. Final Quality Control and Documentation
• Full performance test run over 24 hours
• Validation of setpoints for temperature, CO₂ (if applicable), and humidity (if applicable)
• Final inspection and cleaning before packaging
• Complete service report
Trust the Experts at American Instrument Exchange
With over 50 years in the lab equipment industry, American Instrument Exchange is a trusted source for high-quality refurbished laboratory incubators. Our proven refurbishment protocol ensures every unit is reliable, accurate, and ready to meet the demands of your lab from day one.
Warranty Information
All used equipment sold by American Instrument Exchange is refurbished/reconditioned, tested to meet specifications, cleaned, and comes with a 90-day warranty from the date of shipment unless otherwise specified. New products include a warranty from the manufacturer. Your warranty is only valid if you have paid your invoice. If your invoice is over 30 days old, warranty work will not be performed until your invoice is paid in full. American Instrument Exchange is not liable for any special or consequential damages that result from the use of, or the inability to use, the materials on this site or the performance of the products,
Exceptions include international sales and items that are agreed to be sold with a lesser warranty or items that are agreed to be sold “as is.”
Should there be visible shipping damage to packaging or concealed shipping damage to item(s) supplied, buyer must communicate such damage to the delivering entity or carrier upon receipt first and to American Instrument the same day item is accepted / signed for. Failure to do so voids warranty. Customer decision to involve / procure third party or OEM service other than American Instrument or AIE assigned vendors to resolve in-warranty instrument failure or defect without first placing a service call to American Instrument voids warranty.
Return & Cancellation Policy
American Instrument Exchange will authorize the return of and issue a full refund for any equipment that is not working as represented and could not be replaced or repaired to the customer’s satisfaction by AIE or a representative of AIE during the warranty period. Returns without prior authorization and an RMA number will not be accepted.
Customers are responsible for proper packaging of the equipment and all included accessories. American Instrument will pay for insurance and shipping costs. Non-inventory items bought specifically to fill customer orders may possibly be returned, but on a case by case basis.
Customers who cancel orders after refurbishing has begun or after delivery where there are no equipment performance issues may be subject to a Restocking/Cancellation Fee of 20% or more and responsible for shipping costs for both the delivery and return.
Ongoing and Extended Support Options
American Instrument Exchange is able to provide additional repair and support services outside the warranty terms for most products that sell.
For biosafety cabinets, clean benches, chemical fume hoods, and other clean air products our team at AIE Laboratory Services can provide certifications, repairs, decontaminations, and other services for customers throughout New England, and guidance and limited technical assistance for any customers in the US and Canada for new or refurbished biosafety cabinets purchased from American Instrument Exchange.
For all other products, the repair service team at American Instrument Exchange can provide both field and depot repair evaluations. We can easily schedule and coordinate the pick-up and transportation of your malfunctioning equipment. By offering hourly rates lower than most OEM service providers and eliminating travel time for technicians, we help reduce repair costs. Furthermore, our lab depot repair service minimizes or eliminates scheduling delays. Our experienced service technicians are qualified to restore your equipment to factory specifications.
Yes, all equipment from American Instrument Exchange comes with a warranty. Used/reconditioned/refurbished equipment is tested to make sure it operates to the manufacturer's specifications and comes with a 90-day warranty (unless otherwise noted). New equipment comes with a warranty from the manufacturer.
How do you test and recondition the equipment?
Testing requirements vary across all the equipment categories we sell. Temperature controlled units are tested with NIST traceable probes and data loggers. Gaskets, external housing, glass, handles, controls and control screens are all thoroughly inspected for integrity and functionality. We test all equipment using the manufacturer's parameters and specifications to confirm that the unit operates properly.
How do products ship from American Instrument Exchange?
We can ship products both nationally and internationally using a well-established network of transporters. Smaller items will ship via UPS. Larger equipment will be palletized and shipped either LTL or air-ride, depending on the specific equipment and/or delivery requirements.
Return and order cancellation policy
American Instrument Exchange will accept the return of any product that is not working as represented and could not be replaced or repaired to the customer's satisfaction during the warranty period. Customers who cancel orders after refurbishing has begun will be subject to a cancellation and restocking fee of between 20% and 40%.
Are discounts available for educational or non-profit institutions, or for bulk purchases?
Yes – call or email us today with a list of equipment you're looking for and we can potentially put together a quote that includes a discount.
How does your price matching policy work?
We strive to keep our pricing competitive and reasonable. If you find comparable items for sale at a lower price from other vendors please send us a link and or quote for the item and we'll do our best to match or beat the price.
Can I see the equipment in person before committing to a purchase?
Customers are welcome to make an appointment to view equipment in our warehouse. Given our workload we may not be able to test or clean the equipment prior to your arrival if you have not committed to an order.
1023 Western Avenue is a working warehouse, not a showroom, and customers should dress appropriately and wear closed toe shoes.
Can I ship products that I purchased elsewhere to American Instrument for repair?
Yes – please see our repair services page for more information.
