Cole-Parmer EchoTherm IN40 Chilling Incubator

Brand : Cole Parmer

Product Code : SKU 3197GG INC

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Cole-Parmer EchoTherm IN40 Chilling/Heating Incubator

Many laboratory procedures require temperatures both above and below ambient conditions, making a traditional heating-only incubator insufficient. The Cole-Parmer EchoTherm IN40 Chilling/Heating Incubator was designed to provide precise temperature control across a broad operating range using advanced Peltier solid-state technology, allowing laboratories to both heat and cool samples without the noise, vibration, refrigerants, or maintenance associated with compressor-based refrigeration systems. With a 55-liter (1.9 cubic foot) chamber, forced-air circulation, and digital PID temperature control, the EchoTherm IN40 is an excellent solution for applications requiring accurate environmental control from 4°C to 70°C.

Unlike conventional refrigerated incubators that utilize compressors and refrigerants, the EchoTherm IN40 relies on thermoelectric Peltier technology to deliver quiet, energy-efficient heating and cooling. This design eliminates refrigerants and moving compressor components while providing rapid temperature stabilization and excellent chamber uniformity. Whether used for molecular biology, microbiology, enzyme studies, protein crystallization, or quality control applications, the EchoTherm IN40 offers dependable performance in a compact benchtop format. Purchasing a refurbished Cole-Parmer EchoTherm IN40 from American Instrument Exchange provides laboratories with a versatile temperature-controlled incubator at substantial savings compared with purchasing new equipment.

Key Features

Approximately 55 L (1.9 cu. ft.) chamber capacity
Peltier solid-state heating and cooling
Temperature range from 4°C to 70°C
Digital PID temperature controller
Temperature stability of ±0.1°C
Temperature accuracy of ±0.2°C
Chamber uniformity of ±0.5°C
Forced-air circulation
LCD digital display
Electronic calibration capability
Audible alarm with automatic shutoff timer
Power failure protection
RS-232 communication interface
Energy-efficient compressor-free operation
90-day warranty from American Instrument Exchange

Designed for Heating and Cooling Applications

The EchoTherm IN40 was developed for laboratories requiring flexible temperature control across a wide operating range. Unlike standard incubators that only provide heating, the IN40 can accurately maintain temperatures as low as 4°C, making it suitable for protocols that require chilled incubation, controlled degradation studies, molecular biology procedures, and storage of temperature-sensitive biological materials.

Its 55-liter chamber accommodates laboratory bottles, culture tubes, microplates, flasks, sample racks, and other commonly used laboratory vessels while maintaining stable environmental conditions through continuous forced-air circulation. The compact footprint makes it well suited for research laboratories where bench space is limited but precise temperature control is essential.

Common Applications

The Cole-Parmer EchoTherm IN40 is commonly used for:

Molecular biology
DNA and RNA hybridization
Protein crystallization
Enzyme reactions
Microbiology
Bacterial culture incubation
Cell-free biochemical assays
Sample conditioning
BOD testing
Stability studies
Quality control testing
Food and beverage laboratories
Environmental testing
Educational research laboratories

Its ability to both heat and cool makes it significantly more versatile than a traditional laboratory incubator, allowing researchers to perform a broader range of temperature-controlled protocols using a single instrument.

Ideal Laboratory Environments

The EchoTherm IN40 is an excellent choice for molecular biology laboratories, microbiology facilities, pharmaceutical research laboratories, biotechnology companies, environmental testing laboratories, food science laboratories, academic research institutions, and industrial quality control departments.

Because it combines heating and cooling in one compact system, it is particularly useful in laboratories that routinely switch between different incubation temperatures or perform multiple research protocols requiring both refrigerated and elevated temperature conditions.

Temperature Recovery and Environmental Stability

The EchoTherm IN40 utilizes PID-controlled Peltier thermoelectric technology combined with forced-air circulation to deliver highly stable chamber temperatures without compressor cycling or refrigerant-based cooling. The absence of compressor vibration makes the unit especially attractive for sensitive analytical procedures where environmental consistency is important.

Operating over a range of 4°C to 70°C, the incubator provides approximately ±0.2°C accuracy, ±0.1°C stability, and ±0.5°C chamber uniformity. Continuous air circulation promotes even temperature distribution throughout the chamber while allowing rapid recovery following routine door openings. Electronic calibration functions and power failure protection further contribute to dependable day-to-day laboratory performance.

Peltier Solid-State Heating and Cooling

The defining feature of the EchoTherm IN40 is its thermoelectric Peltier heating and cooling system. Unlike compressor-based refrigerated incubators, Peltier technology transfers heat electronically, eliminating refrigerants, reducing mechanical wear, and producing exceptionally quiet operation. The result is an energy-efficient incubator capable of maintaining stable temperatures with minimal maintenance requirements.

Additional features—including an LCD display, programmable timer with audible alarm, RS-232 communication, forced-air circulation, and electronic calibration capability—make the EchoTherm IN40 a versatile incubator for laboratories requiring reliable temperature control across a broad range of scientific applications.

Sample Storage Recommendations

The 55-liter (1.9 cubic foot) chamber of the Cole-Parmer EchoTherm IN40 provides flexible storage space for laboratories performing both refrigerated and heated incubation protocols. Its tall chamber design accommodates culture bottles, Erlenmeyer flasks, sample racks, reagent containers, Petri dishes, microplates, and tube racks while maintaining excellent temperature uniformity through forced-air circulation.

To achieve the best temperature consistency, samples should be distributed evenly across the adjustable shelves without blocking airflow from the circulation fan. Leaving adequate space between containers promotes rapid temperature recovery and ensures that chilled and heated air reaches all areas of the chamber.

Because the EchoTherm IN40 operates over a wide temperature range, many laboratories use the same instrument for multiple workflows, including refrigerated sample conditioning, enzyme reactions, microbiological incubation, and elevated-temperature stability studies, reducing the need for separate dedicated incubators.

Energy Efficiency and Operating Costs

The EchoTherm IN40 utilizes Peltier thermoelectric technology, eliminating compressors, refrigerants, and many of the mechanical components associated with traditional refrigerated incubators. This solid-state design operates quietly, produces virtually no vibration, and generally requires less maintenance over the life of the instrument.

The PID-controlled heating and cooling system automatically maintains the programmed chamber temperature while minimizing energy consumption. Laboratories also benefit from reduced maintenance requirements since there are no compressor assemblies or refrigerant circuits to service.

For facilities that routinely require temperatures both above and below ambient, the EchoTherm IN40 can often replace two separate incubators, helping conserve valuable bench space while simplifying laboratory workflows.

Key Specifications

Specification	Details
Manufacturer	Cole-Parmer
Model	EchoTherm IN40
Incubator Type	Chilling/Heating Incubator
Chamber Capacity	Approximately 55 L (1.9 cu. ft.)
Temperature Range	4°C to 70°C
Heating/Cooling Technology	Peltier Thermoelectric
Controller	Digital PID
Temperature Accuracy	±0.2°C
Temperature Stability	±0.1°C
Chamber Uniformity	±0.5°C
Air Circulation	Forced Air
Display	LCD Digital
Communications	RS-232 Interface
Timer	99 Hours with Audible Alarm and Auto-Off
Interior Dimensions	14" W × 10" D × 24" H
Exterior Dimensions	22.25" W × 18.5" D × 28.25" H
Electrical Requirements	95–265 VAC Universal Power Supply

Specifications are believed to be accurate but may vary depending on factory-installed options. Please verify all specifications prior to purchase.

Frequently Asked Questions

How quickly can the EchoTherm IN40 switch between heating and cooling?

The Peltier thermoelectric system transitions efficiently between heating and cooling without the delays associated with compressor-based refrigeration. Actual recovery times depend on the target temperature, sample load, and ambient laboratory conditions.

Does the EchoTherm IN40 use refrigerant?

No. The incubator uses a solid-state Peltier heating and cooling module, so it operates without refrigerants, compressors, or refrigeration maintenance.

Is this incubator suitable for temperature-sensitive analytical work?

Yes. Because there is no compressor cycling, the EchoTherm IN40 produces very little vibration and minimal operational noise, making it an excellent choice for applications where environmental stability is important.

Can this incubator maintain temperatures below room temperature?

Yes. The EchoTherm IN40 can cool samples to 4°C, making it useful for refrigerated incubation, sample conditioning, BOD testing, molecular biology protocols, and other applications requiring temperatures below ambient.

What kinds of laboratories benefit most from this model?

The EchoTherm IN40 is frequently used in molecular biology laboratories, environmental testing facilities, pharmaceutical quality control labs, biotechnology companies, food science laboratories, forensic laboratories, and university research programs requiring flexible temperature control.

Is this model programmable?

The standard IN40 provides digital temperature control and timer functions but is not fully programmable. Laboratories requiring multi-step programmed temperature profiles should consider the EchoTherm IN45 series instead.

What is the benefit of the forced-air circulation system?

The internal circulation fan continuously moves conditioned air throughout the chamber, helping minimize temperature gradients and ensuring samples on every shelf experience consistent incubation conditions.

Why purchase a refurbished Cole-Parmer EchoTherm IN40 from American Instrument Exchange?

Purchasing a refurbished Cole-Parmer EchoTherm IN40 from American Instrument Exchange provides laboratories with a versatile temperature-controlled incubator at substantial savings compared with purchasing new equipment. Featuring Peltier heating and cooling, 4°C to 70°C operation, PID temperature control, forced-air circulation, and quiet, vibration-free performance, the EchoTherm IN40 is an excellent solution for research, analytical, and quality control laboratories requiring dependable temperature control. Every incubator is inspected and tested prior to shipment and includes a 90-day warranty for added confidence.

Testing Procedures for Used and Refurbished Laboratory Incubators
Ensure Quality and Stability Before Use

Used and refurbished laboratory incubators from American Instrument Exchange are thoroughly tested to ensure optimal performance and temperature stability with laboratory safety standards. Each unit undergoes a detailed inspection and functionality assessment to meet the needs of research, clinical, and industrial labs.

Why Testing Used Laboratory Incubators Is Essential

Before a laboratory incubator is reintroduced into any work environment, it must be tested for:
• Temperature uniformity and accuracy
• Airflow and humidity control (if applicable)
• Door seal integrity and insulation effectiveness
• Electrical and safety system compliance

Comprehensive testing reduces the risk of culture loss, contamination, and equipment failure—especially critical in applications involving cell culture, microbiology, pharmaceutical research, and diagnostics.

Our multi-point testing protocol for used and refurbished incubators ensures reliability, safety, and performance across all models and brands.

Key Testing Procedures for Refurbished and Used Laboratory Incubators

1. Initial Visual Inspection
• Check for cosmetic damage, corrosion, and wear to exterior surfaces, door hinges, and gasket seals
• Inspect power cord, wiring, and display panel for any defects or signs of tampering
• Confirm that shelves, chamber components, and internal fixtures are present and undamaged

2. Functional Testing
• Power on the incubator and verify all display indicators and alarms function correctly
• Test door latch and seal mechanisms for proper closure and insulation
• Run basic temperature cycles to ensure the unit maintains stability over time

3. Temperature Accuracy and Uniformity Tests
• Test internal sensors and controllers using temperature probes
• Measure temperature consistency at multiple chamber locations over several hours
• Confirm that programmable temperature settings respond accurately

4. Airflow and Humidity Control (if applicable)
• Test internal fan operation and airflow distribution
• For humidified incubators, inspect and test humidity reservoirs, sensors, and control systems
• Check for condensation buildup and confirm environmental stability

5. Electrical Safety and Compliance Checks
• Ensure all electrical components are properly grounded
• Perform insulation resistance and leakage current tests
• Verify compliance with current electrical safety standards for laboratory equipment

6. Final Quality Assurance Checklist
• Perform full cycle testing at various temperature setpoints
• Document performance benchmarks and results

All refurbished incubators from American Instrument Exchange are backed by our commitment to quality and precision. With our strict testing procedures, you can rely on your incubator to deliver dependable results from day one.

Repair and Refurbishment Protocol for Used Laboratory Incubators
Performance and Quality from American Instrument Exchange

At American Instrument Exchange, every used laboratory incubator we sell goes through a repair and refurbishment protocol. Whether it’s a standard, CO₂, or refrigerated incubator, our goal is to restore each unit to laboratory-level performance—ensuring temperature accuracy, environmental stability, and long-term reliability in your lab.

Why Choose a Refurbished Laboratory Incubator from American Instrument Exchange?

• Fully tested for performance and safety
• Backed by a warranty
• Cost-effective alternative to new equipment
• Environmentally sustainable through reuse and restoration
• Refurbished by expert technicians with decades of lab equipment experience

Step-by-Step Refurbishment Protocol

Every incubator at American Instrument Exchange follows this comprehensive, multi-stage process:

1. Initial Intake & Inspection
• Visual inspection for cosmetic wear, corrosion, dents, or broken components
• Mechanical assessment of door hinges, gaskets, seals, and chamber components
• Document any missing parts or issues requiring repair or replacement

2. Cleaning and Decontamination
• Thorough internal and external cleaning using non-abrasive solutions
• Decontamination/cleaning of surfaces to remove biological, chemical, or particulate residue
• Cleaning of removable parts (e.g., shelves, trays, etc.)

3. Mechanical and Electrical Repair
• Repair or replacement of worn mechanical components such as door latches, fans, hinges, and seals
• Evaluation and repair of control panels, switches, thermostats, and displays
• Inspection and testing of wiring, fuses, relays, and power supplies

4. Environmental Control System Assessment
• For CO₂ incubators: CO₂ sensors, regulators, and gas delivery systems are tested
• For refrigerated incubators: compressors, condensers, and cooling systems are evaluated for performance and leaks
• Fan motors and airflow systems are tested to ensure uniform environmental conditions

5. Temperature and Sensor Testing
• All temperature sensors and controllers are tested using thermometers/probes
• Uniformity and accuracy tested at multiple chamber locations
• For humidified or CO₂ incubators, humidity and CO₂ stability are verified

6. Safety System Testing
• Test of over-temperature protection systems and alarms
• Evaluation of door sensors, safety interlocks, and power failure recovery

7. Final Quality Control and Documentation
• Full performance test run over 24 hours
• Validation of setpoints for temperature, CO₂ (if applicable), and humidity (if applicable)
• Final inspection and cleaning before packaging
• Complete service report

Trust the Experts at American Instrument Exchange

With over 50 years in the lab equipment industry, American Instrument Exchange is a trusted source for high-quality refurbished laboratory incubators. Our proven refurbishment protocol ensures every unit is reliable, accurate, and ready to meet the demands of your lab from day one.

Warranty Information

All used equipment sold by American Instrument Exchange is refurbished/reconditioned, tested to meet specifications, cleaned, and comes with a 90-day warranty from the date of shipment unless otherwise specified. New products include a warranty from the manufacturer. Your warranty is only valid if you have paid your invoice. If your invoice is over 30 days old, warranty work will not be performed until your invoice is paid in full. American Instrument Exchange is not liable for any special or consequential damages that result from the use of, or the inability to use, the materials on this site or the performance of the products,

Exceptions include international sales and items that are agreed to be sold with a lesser warranty or items that are agreed to be sold “as is.”

Should there be visible shipping damage to packaging or concealed shipping damage to item(s) supplied, buyer must communicate such damage to the delivering entity or carrier upon receipt first and to American Instrument the same day item is accepted / signed for. Failure to do so voids warranty. Customer decision to involve / procure third party or OEM service other than American Instrument or AIE assigned vendors to resolve in-warranty instrument failure or defect without first placing a service call to American Instrument voids warranty.

Return & Cancellation Policy

American Instrument Exchange will authorize the return of and issue a full refund for any equipment that is not working as represented and could not be replaced or repaired to the customer’s satisfaction by AIE or a representative of AIE during the warranty period. Returns without prior authorization and an RMA number will not be accepted.

Customers are responsible for proper packaging of the equipment and all included accessories. American Instrument will pay for insurance and shipping costs. Non-inventory items bought specifically to fill customer orders may possibly be returned, but on a case by case basis.

Customers who cancel orders after refurbishing has begun or after delivery where there are no equipment performance issues may be subject to a Restocking/Cancellation Fee of 20% or more and responsible for shipping costs for both the delivery and return.

Ongoing and Extended Support Options

American Instrument Exchange is able to provide additional repair and support services outside the warranty terms for most products that sell.

For biosafety cabinets, clean benches, chemical fume hoods, and other clean air products our team at AIE Laboratory Services can provide certifications, repairs, decontaminations, and other services for customers throughout New England, and guidance and limited technical assistance for any customers in the US and Canada for new or refurbished biosafety cabinets purchased from American Instrument Exchange.

For all other products, the repair service team at American Instrument Exchange can provide both field and depot repair evaluations. We can easily schedule and coordinate the pick-up and transportation of your malfunctioning equipment. By offering hourly rates lower than most OEM service providers and eliminating travel time for technicians, we help reduce repair costs. Furthermore, our lab depot repair service minimizes or eliminates scheduling delays. Our experienced service technicians are qualified to restore your equipment to factory specifications.

Please contact our team at info@americaninstrument.com for more details.

FAQ

Does the equipment come with a warranty?

Yes, all equipment from American Instrument Exchange comes with a warranty.
Used/reconditioned/refurbished equipment is tested to make sure it operates to the manufacturer's specifications and comes with a 90-day warranty (unless otherwise noted). New equipment comes with a warranty from the manufacturer.

How do you test and recondition the equipment?

Testing requirements vary across all the equipment categories we sell. Temperature controlled units are tested with NIST traceable probes and data loggers. Gaskets, external housing, glass, handles, controls and control screens are all thoroughly inspected for integrity and functionality.
We test all equipment using the manufacturer's parameters and specifications to confirm that the unit operates properly.

How do products ship from American Instrument Exchange?

We can ship products both nationally and internationally using a well-established network of transporters. Smaller items will ship via UPS. Larger equipment will be palletized and shipped either LTL or air-ride, depending on the specific equipment and/or delivery requirements.

Return and order cancellation policy

American Instrument Exchange will accept the return of any product that is not working as represented and could not be replaced or repaired to the customer's satisfaction during the warranty period. Customers who cancel orders after refurbishing has begun will be subject to a cancellation and restocking fee of between 20% and 40%.

Are discounts available for educational or non-profit institutions, or for bulk purchases?

Yes – call or email us today with a list of equipment you're looking for and we can potentially put together a quote that includes a discount.

How does your price matching policy work?

We strive to keep our pricing competitive and reasonable. If you find comparable items for sale at a lower price from other vendors please send us a link and or quote for the item and we'll do our best to match or beat the price.

Can I see the equipment in person before committing to a purchase?

Customers are welcome to make an appointment to view equipment in our warehouse. Given our workload we may not be able to test or clean the equipment prior to your arrival if you have not committed to an order.

1023 Western Avenue is a working warehouse, not a showroom, and customers should dress appropriately and wear closed toe shoes.

Can I ship products that I purchased elsewhere to American Instrument for repair?

Yes – please see our repair services page for more information.