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LAB EQUIPMENT REPAIRS, INCLUDING ULTRALOW FREEZERS, FRIDGES, CENTRIFUGES AND MORE - Click here for details
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Fisher Scientific Isotemp 650D General Purpose Incubator

Fully Tested & Warrantied*
Brand : Fisher
Product Code : SKU 3111 INC
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Fisher Scientific Isotemp 650D General Purpose Incubator

The Fisher Scientific Isotemp 650D Incubator is a large-capacity general purpose laboratory incubator designed for microbiology, clinical, pharmaceutical, industrial, and research applications requiring stable temperatures above ambient. With a 5.0 cu. ft. chamber, PID microprocessor temperature control, 0.1°C setpoint resolution, and an operating range of 30°C to 75°C, the Isotemp 650D provides the capacity and temperature performance needed for a wide range of routine laboratory procedures.

Available used and refurbished from American Instrument Exchange, the Fisher Isotemp 650D is particularly useful for laboratories that need more than simple static incubation. An internal 120V electrical outlet allows compatible equipment such as a laboratory shaker or stirrer to operate inside the temperature-controlled chamber, expanding the incubator's usefulness for applications requiring simultaneous heating and agitation.

Key Features

  • 5.0 cu. ft. general purpose incubation chamber

  • 30°C to 75°C operating temperature range

  • 0.1°C temperature setpoint resolution

  • ±0.7°C temperature uniformity

  • PID microprocessor temperature control

  • Internal 120V electrical outlet for compatible laboratory equipment

  • Accommodates up to 10 shelves

  • Heated airflow designed for uniform chamber conditions

  • Digital temperature display and operating indicators

  • Built-in backup temperature control

  • Circuit-breaker protection

  • 120V, 60 Hz electrical configuration

  • Professionally inspected and temperature tested by American Instrument Exchange

  • 90-day warranty included

Fisher Scientific Isotemp 650D Incubator Overview

The Fisher Isotemp 650D is a spacious general purpose incubator designed for laboratories that need considerably more usable chamber space than a small benchtop model. Its 5.0 cu. ft. interior can accommodate numerous samples simultaneously, making it a practical choice for busy microbiology laboratories, quality-control departments, research facilities, and other environments with regular incubation requirements.

Temperature is controlled using a PID microprocessor system over a range of 30°C to 75°C, provided the selected operating temperature remains sufficiently above ambient. Setpoints can be adjusted in 0.1°C increments, giving researchers straightforward control for protocols requiring repeatable elevated temperatures.

Heated air is distributed throughout the chamber to promote consistent conditions across the usable interior. Temperature uniformity is rated at approximately ±0.7°C, helping samples positioned on different shelves experience similar incubation conditions.

One of the most useful features of the Isotemp 650D is its internal 120V electrical outlet. Compatible powered equipment can be operated inside the chamber, allowing the incubator to support workflows involving both elevated temperature and mechanical agitation or stirring. This added flexibility can make the 650D more useful than a basic static incubator for laboratories with changing experimental requirements.

Common Applications

The Fisher Isotemp 650D is well suited for routine incubation procedures in microbiology, histology, biotechnology, pharmaceutical, clinical, environmental, industrial, and academic laboratories. Typical applications include bacterial culture, microbiological testing, slide drying and staining, paraffin embedding, sample conditioning, media warming, biochemical procedures, stability studies, and quality-control testing.

The internal electrical outlet also expands the range of possible applications. A compatible laboratory shaker can be operated within the chamber for temperature-controlled agitation when the dimensions, electrical requirements, and operating temperature of the shaker are appropriate.

Laboratories performing microbiological work may also use the Isotemp 650D alongside biosafety cabinets for controlled sample handling and laboratory centrifuges for separation and sample preparation. Laboratory refrigerators and laboratory freezers provide complementary storage for cultures, media, reagents, and other temperature-sensitive materials.

Sample Types & Incubation Recommendations

The Fisher Isotemp 650D is a general purpose incubator rather than a CO₂ or refrigerated model. It is best suited for laboratory procedures requiring controlled temperatures between 30°C and 75°C without regulated CO₂, humidity, or sub-ambient temperature capability.

Common Samples & Applications

  • Bacterial and microbiological cultures

  • Culture media

  • Histology slides

  • Paraffin-embedding materials

  • Environmental samples

  • Pharmaceutical quality-control samples

  • Industrial and research specimens

  • Temperature-conditioning and stability samples

Typical Laboratory Vessels & Equipment

  • Petri and culture dishes

  • Culture bottles

  • Erlenmeyer flasks

  • Test tubes and tube racks

  • Media bottles

  • Sample containers

  • Compatible laboratory shakers

  • Compatible stirring equipment

The chamber can accommodate up to ten shelves, allowing laboratories to configure the interior for numerous smaller samples or remove shelving to create additional clearance for larger vessels and powered equipment.

Because the Isotemp 650D does not regulate carbon dioxide, it should not be used as a substitute for a dedicated CO₂ incubator when cell culture protocols require controlled CO₂ and high humidity.

Temperature Control & Uniformity

Temperature performance is the most important consideration for a general purpose incubator, and the Fisher Isotemp 650D combines microprocessor control with forced-air circulation to maintain consistent conditions throughout its relatively large chamber.

The PID microprocessor controller continuously monitors chamber temperature and adjusts heater output to maintain the selected setpoint. Temperatures can be programmed in 0.1°C increments, allowing the incubator to accommodate a wide variety of laboratory procedures within its operating range.

Temperature uniformity is approximately ±0.7°C, helping minimize differences between samples located in different areas of the chamber. Heated airflow circulates throughout the interior rather than concentrating heat around a single portion of the chamber, an important consideration when the incubator is loaded across multiple shelves.

The control system also incorporates backup temperature protection designed to safeguard samples if the primary control system experiences a fault. This additional protection can be particularly valuable during extended incubation periods when samples may remain unattended overnight or over a weekend.

The internal electrical outlet adds another dimension to temperature-controlled work. Researchers can operate compatible equipment within the heated environment, although the electrical load, heat generated by the equipment, available chamber space, and maximum operating temperature of the accessory should always be considered before use.

Fisher Scientific Isotemp 650D Incubator Specifications

Specification Details
Manufacturer Fisher Scientific
Model Isotemp 650D
Equipment Type General Purpose Laboratory Incubator
Chamber Capacity 5.0 cu. ft.
Temperature Range 30°C to 75°C
Minimum Operating Temperature Approximately 5°C above ambient
Temperature Uniformity ±0.7°C
Setpoint Resolution 0.1°C
Temperature Control PID microprocessor
Airflow Heated forced-air circulation
Maximum Shelves Up to 10
Internal Electrical Outlet 120V
Safety Control Backup temperature protection
Electrical Protection Circuit breaker
Electrical Requirements 120V, 60 Hz
Interior Dimensions Approximately 20"W × 20"D × 22"H
Exterior Dimensions Approximately 24"W × 25"D × 33"H
Approximate Weight 145 lb.

Specifications may vary according to production date and individual unit configuration. Confirm shelving, electrical requirements, dimensions, accessories, and other specifications for the individual incubator before purchase.

Fisher Scientific Isotemp 650D Incubator Frequently Asked Questions

What is the temperature range of the Fisher Isotemp 650D?

The Isotemp 650D operates from approximately 30°C to 75°C, with the operating setpoint maintained sufficiently above ambient temperature. Temperature can be selected in 0.1°C increments for precise adjustment across different laboratory protocols.

What is the internal electrical outlet used for?

The internal 120V outlet allows compatible powered laboratory equipment to operate inside the temperature-controlled chamber. For example, an appropriately sized shaker or stirrer may be used for experiments requiring both elevated temperature and agitation. Equipment dimensions, electrical load, heat generation, and temperature ratings should always be verified before use.

How much capacity does the Fisher Isotemp 650D provide?

The Isotemp 650D provides approximately 5.0 cu. ft. of chamber capacity and can accommodate up to ten shelves. The shelving configuration can be adjusted according to the size and quantity of samples being incubated.

Is the Isotemp 650D suitable for microbiology applications?

Yes. The Isotemp 650D is well suited for many routine microbiology applications, including bacterial culture, microbiological testing, media warming, and sample incubation, provided the protocol falls within the unit's temperature and environmental capabilities.

Is the Fisher Isotemp 650D a CO₂ incubator?

No. The Isotemp 650D is a general purpose laboratory incubator and does not regulate CO₂ concentration or provide the controlled high-humidity atmosphere typically required for conventional mammalian cell culture.

Is this Fisher Isotemp 650D refurbished?

Yes. Used Fisher Isotemp 650D incubators offered by American Instrument Exchange are inspected, cleaned, and tested prior to shipment. Temperature performance is evaluated to verify proper operation, and refurbished equipment includes a 90-day warranty.

Testing Procedures for Used and Refurbished Laboratory Incubators
Ensure Quality and Stability Before Use

Used and refurbished laboratory incubators from American Instrument Exchange are thoroughly tested to ensure optimal performance and temperature stability with laboratory safety standards. Each unit undergoes a detailed inspection and functionality assessment to meet the needs of research, clinical, and industrial labs.

Why Testing Used Laboratory Incubators Is Essential

Before a laboratory incubator is reintroduced into any work environment, it must be tested for:
• Temperature uniformity and accuracy
• Airflow and humidity control (if applicable)
• Door seal integrity and insulation effectiveness
• Electrical and safety system compliance

Comprehensive testing reduces the risk of culture loss, contamination, and equipment failure—especially critical in applications involving cell culture, microbiology, pharmaceutical research, and diagnostics.

Our multi-point testing protocol for used and refurbished incubators ensures reliability, safety, and performance across all models and brands.

Key Testing Procedures for Refurbished and Used Laboratory Incubators

1. Initial Visual Inspection
• Check for cosmetic damage, corrosion, and wear to exterior surfaces, door hinges, and gasket seals
• Inspect power cord, wiring, and display panel for any defects or signs of tampering
• Confirm that shelves, chamber components, and internal fixtures are present and undamaged

2. Functional Testing
• Power on the incubator and verify all display indicators and alarms function correctly
• Test door latch and seal mechanisms for proper closure and insulation
• Run basic temperature cycles to ensure the unit maintains stability over time

3. Temperature Accuracy and Uniformity Tests
• Test internal sensors and controllers using temperature probes
• Measure temperature consistency at multiple chamber locations over several hours
• Confirm that programmable temperature settings respond accurately

4. Airflow and Humidity Control (if applicable)
• Test internal fan operation and airflow distribution
• For humidified incubators, inspect and test humidity reservoirs, sensors, and control systems
• Check for condensation buildup and confirm environmental stability

5. Electrical Safety and Compliance Checks
• Ensure all electrical components are properly grounded
• Perform insulation resistance and leakage current tests
• Verify compliance with current electrical safety standards for laboratory equipment

6. Final Quality Assurance Checklist
• Perform full cycle testing at various temperature setpoints
• Document performance benchmarks and results

All refurbished incubators from American Instrument Exchange are backed by our commitment to quality and precision. With our strict testing procedures, you can rely on your incubator to deliver dependable results from day one.

Repair and Refurbishment Protocol for Used Laboratory Incubators
Performance and Quality from American Instrument Exchange

At American Instrument Exchange, every used laboratory incubator we sell goes through a repair and refurbishment protocol. Whether it’s a standard, CO₂, or refrigerated incubator, our goal is to restore each unit to laboratory-level performance—ensuring temperature accuracy, environmental stability, and long-term reliability in your lab.

Why Choose a Refurbished Laboratory Incubator from American Instrument Exchange?

• Fully tested for performance and safety
• Backed by a warranty
• Cost-effective alternative to new equipment
• Environmentally sustainable through reuse and restoration
• Refurbished by expert technicians with decades of lab equipment experience

Step-by-Step Refurbishment Protocol

Every incubator at American Instrument Exchange follows this comprehensive, multi-stage process:

1. Initial Intake & Inspection
• Visual inspection for cosmetic wear, corrosion, dents, or broken components
• Mechanical assessment of door hinges, gaskets, seals, and chamber components
• Document any missing parts or issues requiring repair or replacement

2. Cleaning and Decontamination
• Thorough internal and external cleaning using non-abrasive solutions
• Decontamination/cleaning of surfaces to remove biological, chemical, or particulate residue
• Cleaning of removable parts (e.g., shelves, trays, etc.)

3. Mechanical and Electrical Repair
• Repair or replacement of worn mechanical components such as door latches, fans, hinges, and seals
• Evaluation and repair of control panels, switches, thermostats, and displays
• Inspection and testing of wiring, fuses, relays, and power supplies

4. Environmental Control System Assessment
• For CO₂ incubators: CO₂ sensors, regulators, and gas delivery systems are tested
• For refrigerated incubators: compressors, condensers, and cooling systems are evaluated for performance and leaks
• Fan motors and airflow systems are tested to ensure uniform environmental conditions

5. Temperature and Sensor Testing
• All temperature sensors and controllers are tested using thermometers/probes
• Uniformity and accuracy tested at multiple chamber locations
• For humidified or CO₂ incubators, humidity and CO₂ stability are verified

6. Safety System Testing
• Test of over-temperature protection systems and alarms
• Evaluation of door sensors, safety interlocks, and power failure recovery

7. Final Quality Control and Documentation
• Full performance test run over 24 hours
• Validation of setpoints for temperature, CO₂ (if applicable), and humidity (if applicable)
• Final inspection and cleaning before packaging
• Complete service report

Trust the Experts at American Instrument Exchange

With over 50 years in the lab equipment industry, American Instrument Exchange is a trusted source for high-quality refurbished laboratory incubators. Our proven refurbishment protocol ensures every unit is reliable, accurate, and ready to meet the demands of your lab from day one.

Warranty Information

All used equipment sold by American Instrument Exchange is refurbished/reconditioned, tested to meet specifications, cleaned, and comes with a 90-day warranty from the date of shipment unless otherwise specified. New products include a warranty from the manufacturer. Your warranty is only valid if you have paid your invoice. If your invoice is over 30 days old, warranty work will not be performed until your invoice is paid in full.  American Instrument Exchange is not liable for any special or consequential damages that result from the use of, or the inability to use, the materials on this site or the performance of the products,

Exceptions include international sales and items that are agreed to be sold with a lesser warranty or items that are agreed to be sold “as is.”

Should there be visible shipping damage to packaging or concealed shipping damage to item(s) supplied, buyer must communicate such damage to the delivering entity or carrier upon receipt first and to American Instrument the same day item is accepted / signed for. Failure to do so voids warranty. Customer decision to involve / procure third party or OEM service other than American Instrument or AIE assigned vendors to resolve in-warranty instrument failure or defect without first placing a service call to American Instrument voids warranty.

Return & Cancellation Policy

American Instrument Exchange will authorize the return of and issue a full refund for any equipment that is not working as represented and could not be replaced or repaired to the customer’s satisfaction by AIE or a representative of AIE during the warranty period. Returns without prior authorization and an RMA number will not be accepted. 

Customers are responsible for proper packaging of the equipment and all included accessories. American Instrument will pay for insurance and shipping costs. Non-inventory items bought specifically to fill customer orders may possibly be returned, but on a case by case basis.

Customers who cancel orders after refurbishing has begun or after delivery where there are no equipment performance issues may be subject to a Restocking/Cancellation Fee of 20% or more and responsible for shipping costs for both the delivery and return.

Ongoing and Extended Support Options

American Instrument Exchange is able to provide additional repair and support services outside the warranty terms for most products that sell.

For biosafety cabinets, clean benches, chemical fume hoods, and other clean air products our team at AIE Laboratory Services can provide certifications, repairs, decontaminations, and other services for customers throughout New England, and guidance and limited technical assistance for any customers in the US and Canada for new or refurbished biosafety cabinets purchased from American Instrument Exchange.

For all other products, the repair service team at American Instrument Exchange can provide both field and depot repair evaluations. We can easily schedule and coordinate the pick-up and transportation of your malfunctioning equipment. By offering hourly rates lower than most OEM service providers and eliminating travel time for technicians, we help reduce repair costs. Furthermore, our lab depot repair service minimizes or eliminates scheduling delays. Our experienced service technicians are qualified to restore your equipment to factory specifications.

Please contact our team at info@americaninstrument.com for more details.

FAQ

Does the equipment come with a warranty?

Yes, all equipment from American Instrument Exchange comes with a warranty.
Used/reconditioned/refurbished equipment is tested to make sure it operates to the manufacturer's specifications and comes with a 90-day warranty (unless otherwise noted). New equipment comes with a warranty from the manufacturer.

How do you test and recondition the equipment?

Testing requirements vary across all the equipment categories we sell. Temperature controlled units are tested with NIST traceable probes and data loggers. Gaskets, external housing, glass, handles, controls and control screens are all thoroughly inspected for integrity and functionality.
We test all equipment using the manufacturer's parameters and specifications to confirm that the unit operates properly.

How do products ship from American Instrument Exchange?

We can ship products both nationally and internationally using a well-established network of transporters. Smaller items will ship via UPS. Larger equipment will be palletized and shipped either LTL or air-ride, depending on the specific equipment and/or delivery requirements.

Return and order cancellation policy

American Instrument Exchange will accept the return of any product that is not working as represented and could not be replaced or repaired to the customer's satisfaction during the warranty period. Customers who cancel orders after refurbishing has begun will be subject to a cancellation and restocking fee of between 20% and 40%.

Are discounts available for educational or non-profit institutions, or for bulk purchases?

Yes – call or email us today with a list of equipment you're looking for and we can potentially put together a quote that includes a discount.

How does your price matching policy work?

We strive to keep our pricing competitive and reasonable. If you find comparable items for sale at a lower price from other vendors please send us a link and or quote for the item and we'll do our best to match or beat the price.

Can I see the equipment in person before committing to a purchase?

Customers are welcome to make an appointment to view equipment in our warehouse. Given our workload we may not be able to test or clean the equipment prior to your arrival if you have not committed to an order.

1023 Western Avenue is a working warehouse, not a showroom, and customers should dress appropriately and wear closed toe shoes.

Can I ship products that I purchased elsewhere to American Instrument for repair?

Yes – please see our repair services page for more information.