Mettler Toledo MS105DU Analytical Balance
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All products ship from our 30,000 sq. ft. Haverhill, MA warehouse
Shipping
All products ship from our 30,000 sq. ft. Haverhill, MA warehouse
The Mettler Toledo MS105DU is a dual-range semi-micro balance designed for laboratories that need 10 µg readability for sensitive quantitative measurements while retaining the flexibility of a larger 120 g analytical weighing range. The balance provides a 42 g fine range with 0.01 mg readability and a full 120 g range with 0.1 mg readability, making it well suited for pharmaceutical, biotechnology, analytical chemistry, quality-control, and research applications.
Available used and refurbished from American Instrument Exchange, the MS105DU combines Mettler Toledo MonoBloc weighing technology with FACT automatic internal adjustment, a glass draft shield, an 80 mm weighing pan, ergonomic ErgoDoors, QuickLock removable glass panels, and integrated weighing applications.
The dual-range architecture allows laboratories to perform semi-micro measurements when 0.1 mg analytical readability is insufficient while still accommodating larger samples and tare vessels up to 120 g.
Each refurbished Mettler Toledo MS105DU is inspected, calibrated, performance tested, and cleaned by American Instrument Exchange and includes a 90-day warranty.
Dual-range semi-micro balance
120 g maximum weighing capacity
42 g fine weighing range
0.01 mg / 10 µg fine-range readability
0.1 mg full-range readability
Typical repeatability as low as 0.015 mg
±0.15 mg linearity limit
Typical USP minimum weight of approximately 30 mg
Approximately 3-second fine-range settling time
Approximately 1.5-second standard-range settling time
MonoBloc weighing cell
FACT automatic internal adjustment
80 mm diameter weighing pan
235 mm usable draft-shield height
Ergonomic ErgoDoor draft shield
QuickLock removable glass panels
High-contrast display
Integrated weighing applications
RS232 and USB-B connectivity
Die-cast aluminum housing
Refurbished and tested by American Instrument Exchange
90-day warranty included
The Mettler Toledo MS105DU occupies the important performance range between conventional analytical and single-range semi-micro balances.
A conventional analytical balance typically provides 0.1 mg readability.
The MS105DU provides that same readability across its broader 120 g weighing range but improves resolution tenfold to 0.01 mg within its 42 g fine range.
This makes the instrument particularly useful for laboratories where some procedures require semi-micro sensitivity while other measurements benefit from greater capacity.
Instead of maintaining separate balances for these workflows, the MS105DU can support both types of measurements within a single instrument.
The MS105DU is well suited for pharmaceutical formulation, analytical standards preparation, gravimetric analysis, biotechnology research, quantitative sample preparation, chemical testing, quality control, environmental analysis, density determination, component weighing, pipette testing, and other procedures requiring high-resolution mass measurement.
Pharmaceutical laboratories can use the MS105DU for reference standards, formulation components, active ingredients, stability-testing samples, and quantitative analytical procedures.
Biotechnology laboratories may use it for compounds, powders, membranes, filters, reagents, and other small research samples.
Analytical and chemical laboratories can use the balance for standards preparation and gravimetric procedures where conventional 0.1 mg readability may not provide sufficient resolution.
The MS105DU is particularly well suited for pharmaceutical manufacturers, biotechnology companies, analytical chemistry laboratories, environmental testing facilities, contract laboratories, quality-control departments, universities, and research organizations.
Its dual-range configuration makes it especially attractive to laboratories that need semi-micro performance for some procedures but do not require 0.01 mg readability throughout the entire 120 g capacity.
The MS105DU provides two levels of weighing resolution.
Within the 42 g fine range, readability is 0.01 mg, equivalent to 10 micrograms.
Across the broader range up to 120 g, readability is 0.1 mg.
Mettler Toledo specifies a repeatability limit of approximately 0.08 mg at nominal load and typical repeatability as low as approximately 0.015 mg under favorable conditions and lower loads.
The specified linearity deviation limit is ±0.15 mg.
This combination gives laboratories the ability to perform demanding semi-micro measurements while retaining enough capacity for conventional analytical weighing.
The 0.01 mg fine-range readability of the MS105DU is equivalent to 10 µg.
This represents ten times finer displayed resolution than a conventional 0.1 mg analytical balance.
That increased sensitivity can be important when weighing very small quantities because each display increment represents a smaller fraction of the total sample mass.
However, readability should not be confused with minimum sample weight.
A balance capable of displaying 0.01 mg changes cannot necessarily weigh a 0.01 mg sample with acceptable quantitative uncertainty.
Mettler Toledo technical data for the MS105DU identifies a typical USP minimum weight of approximately 30 mg under specified conditions.
Minimum sample weight depends on repeatability, environmental conditions, installation quality, balance performance, and the uncertainty requirements of the weighing procedure.
For regulated pharmaceutical work, laboratories should determine and document minimum sample weight under their actual operating conditions.
The manufacturer's typical value is useful for comparing the MS105DU with conventional analytical balances and other semi-micro models.
Understanding the two ranges of the MS105DU is important when selecting the balance for a particular method.
The finest 0.01 mg readability is available within the 42 g fine range.
The balance continues weighing up to 120 g, but readability changes to 0.1 mg in the broader range.
Laboratories should therefore consider the combined mass of samples, weighing vessels, and tare containers when determining whether a method can take advantage of semi-micro resolution.
For methods routinely requiring 10 µg readability with substantially heavier tare loads, a different balance architecture may be more appropriate.
The MS105DU uses Mettler Toledo's MonoBloc weighing-cell technology.
MonoBloc cells were engineered to provide strong repeatability, rapid response, mechanical durability, and long-term weighing stability.
The weighing cell is housed within a robust die-cast aluminum enclosure designed to protect sensitive components during routine laboratory use.
This combination helped make the MS series a widely used platform in pharmaceutical, research, and quality-control laboratories.
The MS105DU incorporates Mettler Toledo FACT automatic internal adjustment.
FACT uses internal reference weights to automatically test and adjust the weighing system when appropriate.
Automatic adjustment helps compensate for changes in environmental conditions, particularly temperature variations that may affect weighing-system response.
This reduces dependence on operators remembering to perform routine manual adjustment.
External verification with appropriate certified weights may still be required according to laboratory quality procedures.
Environmental control becomes increasingly important at 0.01 mg readability.
Air currents from HVAC systems, open doors, fans, and nearby movement can affect stabilization.
Vibration from centrifuges, shakers, pumps, compressors, refrigerators, foot traffic, or unstable laboratory benches can also influence results.
Static electricity can be particularly troublesome when weighing powders, plastic vessels, filters, weighing paper, or other insulating materials.
The MS105DU's enclosed draft shield helps protect the weighing area from air movement, but good laboratory technique remains essential for demanding semi-micro measurements.
Samples and weighing vessels should ideally be close to the temperature of the balance environment before sensitive measurements are performed.
A warm or cold object placed inside the draft shield can create convection currents.
Those air movements can produce apparent changes in mass even when the sample itself is stable.
Temperature differences can also affect air buoyancy.
Allowing samples, containers, and calibration weights to equilibrate before critical measurements can improve repeatability.
The MS105DU incorporates Mettler Toledo's ergonomic ErgoDoor design.
The draft-shield doors are arranged so that an operator can open one side while placing a sample into the chamber with the opposite hand.
The doors also remain within the footprint of the balance when opened, helping conserve bench space.
Mettler Toledo specifies approximately 235 mm of usable height within the weighing chamber.
The draft-shield glass panels use Mettler Toledo's QuickLock system.
Panels can be removed for cleaning without tools and reinstalled without requiring the entire balance to be moved.
This makes it easier to remove spilled powders, chemical residue, dust, and other contaminants from the weighing chamber.
Simplified cleaning is particularly useful in pharmaceutical and multi-user laboratories where different compounds may be weighed on the same instrument.
The MS105DU uses a high-contrast display designed for clear presentation of weighing results and instrument information.
Although less elaborate than the touchscreen interfaces used on newer Mettler Toledo XSR and XPR balances, the display provides straightforward access to routine weighing functions and applications.
For laboratories primarily interested in weighing performance rather than advanced touchscreen workflows, the simpler interface can be an advantage.
The MS platform supports applications for common laboratory weighing procedures.
Depending on configuration, these include basic weighing, piece counting, percentage weighing, checkweighing, statistics, formulation, totaling, dynamic weighing, density determination, and pipette-checking workflows.
Integrated applications can reduce manual calculations and help standardize repetitive laboratory procedures.
The MS105DU can also be configured for gravimetric pipette testing.
Mettler Toledo designed the platform so an evaporation trap can be installed to convert the balance into a pipette-checking station.
The integrated application can then guide the technician through the testing process.
This provides another potential use for laboratories maintaining pipettes as part of an internal quality or calibration program.
The MS105DU supports RS232 and USB-B connectivity for communication with compatible computers, printers, and laboratory peripherals.
Electronic data transfer can reduce dependence on manually copying measurements from the display.
The balance also supports basic electronic documentation and GLP/GMP-oriented output when used with appropriate peripherals and laboratory procedures.
| Specification | Mettler Toledo MS105DU |
|---|---|
| Balance Type | Dual-Range Semi-Micro Balance |
| Maximum Capacity | 120 g |
| Fine Range Capacity | 42 g |
| Fine Range Readability | 0.01 mg / 10 µg |
| Full Range Readability | 0.1 mg |
| Repeatability Limit at Nominal Load | 0.08 mg |
| Typical Repeatability | As Low as Approx. 0.015 mg |
| Linearity Limit | ±0.15 mg |
| Typical Linearity Deviation | Approx. 0.05 mg |
| Typical USP Minimum Weight | Approx. 30 mg |
| Fine Range Settling Time | Approx. 3 seconds |
| Standard Range Settling Time | Approx. 1.5 seconds |
| Adjustment | Internal Automatic / FACT |
| Weighing Technology | MonoBloc |
| Weighing Pan | Ø80 mm |
| Draft Shield | Glass ErgoDoor |
| Usable Draft-Shield Height | 235 mm |
| Display | High-Contrast Display |
| Interfaces | RS232, USB-B |
| Housing | Die-Cast Aluminum / Polymer Components |
| Dimensions | Approx. 247 mm W × 358 mm D × 331 mm H |
| Weight | Approx. 6.8 kg |
| Legal for Trade | No |
| Condition | Used & Refurbished |
| Testing | Accuracy, Repeatability, Linearity, Corner Load, Adjustment & Functional Testing |
| Warranty | 90 Days from American Instrument Exchange |
A conventional analytical balance typically provides 0.1 mg readability.
The MS105DU provides the same 0.1 mg readability across its broader 120 g range but adds a 42 g fine range with 0.01 mg readability.
This allows the MS105DU to perform measurements requiring ten times finer displayed resolution.
For laboratories that routinely work with samples comfortably above the minimum-weight capabilities of a conventional analytical balance, 0.1 mg may be sufficient.
For smaller samples or procedures requiring lower measurement uncertainty, the MS105DU's semi-micro fine range can provide a meaningful advantage.
The MS105 and MS105DU both provide a maximum capacity of 120 g, but their weighing architectures differ.
The MS105 is a single-range semi-micro balance providing 0.01 mg readability throughout its 120 g capacity.
The MS105DU is a dual-range model providing 0.01 mg readability within a 42 g fine range and 0.1 mg readability across the broader 120 g range.
The MS105 is more appropriate when 10 µg readability is required across heavier loads.
The MS105DU provides a flexible alternative when semi-micro resolution is primarily required for smaller samples.
The MS105DU and MS205DU use similar dual-range semi-micro architecture.
The MS105DU provides 120 g maximum capacity with a 42 g fine range.
The MS205DU increases maximum capacity to 220 g and provides a larger 82 g fine range.
Both offer 0.01 mg fine-range readability and 0.1 mg broader-range readability.
The MS205DU is therefore better suited for laboratories using heavier tare vessels or larger samples, while the MS105DU provides the same fundamental weighing concept in a lower-capacity configuration.
The choice between dual-range and single-range semi-micro balances depends on the laboratory's actual weighing procedures.
A single-range semi-micro balance provides 0.01 mg readability throughout its full capacity.
A dual-range model such as the MS105DU provides the finest resolution over a defined portion of the weighing range and 0.1 mg readability across the remaining capacity.
Dual-range architecture can provide an attractive balance between sensitivity and cost for laboratories where most semi-micro samples remain within the fine range.
The MS105DU is particularly well suited for pharmaceutical and quality-control environments because it combines semi-micro resolution with automatic adjustment, robust construction, draft protection, electronic documentation, and a relatively straightforward user interface.
Its approximately 30 mg typical USP minimum weight also provides a useful reference point for methods involving small quantities of active ingredients, reference standards, or formulation components.
Laboratories should still establish actual minimum sample weight and routine verification requirements under their own operating conditions.
Each used Mettler Toledo MS105DU offered by American Instrument Exchange undergoes inspection, cleaning, calibration, and functional testing before shipment.
Technicians inspect the housing, display, weighing chamber, weighing pan, draft-shield panels, leveling system, power components, interfaces, and installed accessories.
The balance is tested with appropriate reference weights at multiple points across its weighing range.
Repeatability testing evaluates measurement consistency through repeated weighing of the same reference load.
Linearity testing evaluates performance at multiple load points, while corner-load testing helps verify consistent response across different positions on the weighing pan.
The 0.01 mg fine range is specifically evaluated because semi-micro performance is a defining capability of the MS105DU.
FACT adjustment, taring, zeroing, interface controls, and other installed functions are also checked.
Following final inspection and cleaning, the balance is prepared for shipment.
Used and refurbished equipment from American Instrument Exchange includes a 90-day warranty unless otherwise specified.
The MS105DU should be installed on a rigid, stable, vibration-resistant balance table away from direct HVAC airflow, doors, fans, and frequently traveled areas.
Centrifuges, shakers, pumps, compressors, and other vibration-producing equipment should not share an unstable bench with the balance when semi-micro measurements are being performed.
After transportation, the balance should be allowed to acclimate to laboratory conditions.
The instrument should then be leveled, FACT adjustment allowed to operate as appropriate, and weighing performance verified according to laboratory quality procedures.
For demanding 0.01 mg measurements, sample temperature, static electricity, airflow, vibration, and operator technique should all be considered.
American Instrument Exchange maintains an extensive inventory of used and refurbished laboratory balances, including analytical balances, semi-micro balances, microbalances, and precision balances for applications ranging from routine sample preparation to high-resolution quantitative analysis.
Labs developing complete analytical or sample-preparation workflows can also source centrifuges, water baths, incubators, laboratory refrigerators, laboratory freezers, and other refurbished laboratory equipment from American Instrument Exchange.
The MS105DU has a maximum weighing capacity of 120 g.
The fine range extends to 42 g.
The balance provides 0.01 mg readability within its 42 g fine range and 0.1 mg readability across the broader range up to 120 g.
The MS105DU belongs to Mettler Toledo's analytical weighing family, but its 0.01 mg fine-range readability makes dual-range semi-micro balance the more descriptive classification.
Mettler Toledo specifies typical repeatability as low as approximately 0.015 mg under favorable measurement conditions.
The model-specific manufacturer specification gives a linearity deviation limit of ±0.15 mg.
Mettler Toledo technical data identifies a typical USP minimum weight of approximately 30 mg under specified conditions.
Mettler Toledo specifies approximately 3 seconds in the 0.01 mg fine range and approximately 1.5 seconds in the standard range.
Yes. The MS105DU incorporates Mettler Toledo FACT automatic internal adjustment.
MonoBloc is Mettler Toledo's weighing-cell technology designed to provide high repeatability, fast response, mechanical durability, and long-term stability.
The MS105 provides 0.01 mg readability throughout its full 120 g capacity. The MS105DU provides 0.01 mg readability within a 42 g fine range and 0.1 mg readability up to 120 g.
The MS105DU provides 120 g maximum capacity and a 42 g fine range. The MS205DU increases those capacities to 220 g and 82 g respectively.
Yes. Mettler Toledo designed the MS semi-micro platform to support gravimetric pipette testing with the appropriate evaporation-trap configuration and application.
Yes. The MS105DU supports RS232 and USB-B connectivity for compatible computers, printers, and laboratory peripherals.
No. Mettler Toledo discontinued the MS105DU in February 2024 and identifies the newer MX105DU as its replacement.
This Mettler Toledo MS105DU is offered used and refurbished by American Instrument Exchange. It is inspected, calibrated, performance tested, cleaned, and supplied with a 90-day warranty.
A refurbished MS105DU provides 10 µg fine-range readability, 120 g overall capacity, FACT automatic adjustment, MonoBloc weighing technology, ergonomic draft protection, and useful laboratory applications at a lower acquisition cost than many current-generation semi-micro balances.
CLICK HERE to see a video of the Mettler Toledo MS105DU on American Instrument Exchange's YouTube channel.
Yes, all equipment from American Instrument Exchange comes with a warranty.
Used/reconditioned/refurbished equipment is tested to make sure it operates to the manufacturer's specifications and comes with a 90-day warranty (unless otherwise noted). New equipment comes with a warranty from the manufacturer.
Testing requirements vary across all the equipment categories we sell. Temperature controlled units are tested with NIST traceable probes and data loggers. Gaskets, external housing, glass, handles, controls and control screens are all thoroughly inspected for integrity and functionality.
We test all equipment using the manufacturer's parameters and specifications to confirm that the unit operates properly.
We can ship products both nationally and internationally using a well-established network of transporters. Smaller items will ship via UPS. Larger equipment will be palletized and shipped either LTL or air-ride, depending on the specific equipment and/or delivery requirements.
American Instrument Exchange will accept the return of any product that is not working as represented and could not be replaced or repaired to the customer's satisfaction during the warranty period. Customers who cancel orders after refurbishing has begun will be subject to a cancellation and restocking fee of between 20% and 40%.
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