Mettler Toledo XPR106H Dual-Range Analytical Balance

Mettler Toledo XPR106H Dual-Range Analytical Balance – Used & Refurbished

The Mettler Toledo XPR106H Dual-Range Analytical Balance is an advanced high-resolution laboratory balance designed for demanding quantitative weighing where conventional analytical-balance resolution may not be sufficient. Its dual-range weighing system provides 0.002 mg / 2 µg readability through a 41 g fine range and 0.005 mg / 5 µg readability through its full 120 g capacity, giving laboratories exceptional sensitivity while retaining practical capacity for analytical samples and weighing vessels.

Available used and refurbished from American Instrument Exchange, the Mettler Toledo XPR106H combines high-resolution weighing with advanced technologies including StaticDetect, SmartGrid, MinWeigh, StatusLight, LevelControl, SmartSens hands-free operation, automatic draft-shield doors, a 7-inch color touchscreen, stored weighing methods, and electronic data connectivity.

This combination makes the XPR106H particularly well suited for pharmaceutical, biotechnology, chemical, environmental, analytical testing, quality-control, and research laboratories where small sample quantities, environmental influences, measurement uncertainty, and data integrity are important considerations.

Each XPR106H is inspected, cleaned, calibrated, and tested for weighing performance before shipment and includes a 90-day warranty from American Instrument Exchange.

Key Features

• Dual-range high-resolution analytical weighing

• 41 g fine-range capacity with 0.002 mg / 2 µg readability

• 120 g full-range capacity with 0.005 mg / 5 µg readability

• Repeatability of approximately 0.003 mg / 3 µg

• Approximately 4-second stabilization time

• Automatic internal adjustment

• StaticDetect electrostatic-charge detection

• SmartGrid weighing platform

• MinWeigh minimum-weight monitoring

• StatusLight balance-status indicator

• LevelControl leveling guidance

• SmartSens infrared sensors

• Automatic draft-shield doors

• 7-inch color touchscreen

• Stored weighing methods

• Electronic results management

• USB and Ethernet connectivity

• LabX-compatible workflow capabilities

• Used, refurbished, calibrated, and tested by American Instrument Exchange

• 90-day warranty included

Overview

The Mettler Toledo XPR106H occupies a specialized position between conventional analytical balances, semi-microbalances, and microbalances.

A typical analytical balance provides 0.1 mg / 100 µg readability.

The XPR106H provides resolution as fine as 2 µg within its 41 g fine range, making its displayed resolution approximately fifty times finer than that of a conventional 0.1 mg analytical balance.

Across its full 120 g capacity, the XPR106H still provides exceptionally fine 5 µg readability.

This combination allows laboratories to perform very high-resolution measurements while retaining substantially more working capacity than many traditional microbalances.

The XPR platform also addresses an important reality of microgram-level weighing: the balance itself is only one part of the measurement system.

Air movement, vibration, static electricity, temperature stability, sample condition, operator technique, and minimum-weight requirements all become increasingly important as resolution improves.

The XPR106H incorporates multiple technologies designed to help users identify and control these influences.

Common Applications

The Mettler Toledo XPR106H is well suited for pharmaceutical formulation, reference-standard preparation, quantitative chemical analysis, gravimetric analysis, filter weighing, residue determination, environmental analysis, small-sample research, quality control, materials characterization, differential weighing, and other high-resolution analytical procedures.

Pharmaceutical and biotechnology laboratories can use the XPR106H when working with potent compounds, expensive materials, reference standards, formulation ingredients, and other substances where reducing sample consumption can provide significant advantages.

Environmental laboratories may use the balance for filters, residues, particulate matter, and other applications involving relatively small changes in mass.

Chemical, materials science, and research laboratories can use its microgram-level resolution for demanding quantitative procedures where conventional 0.1 mg analytical resolution is insufficient.

Ideal Laboratory Types

The XPR106H is particularly well suited for pharmaceutical, biotechnology, chemical, environmental, materials science, analytical testing, metrology, research, and quality-control laboratories.

Its combination of very high resolution and advanced quality-management features makes it especially useful in laboratories operating under tightly controlled analytical procedures.

The balance can also be valuable when samples are expensive, scarce, potent, hazardous, or difficult to obtain.

Reducing the amount of material required for a measurement can conserve valuable samples while potentially simplifying subsequent handling and disposal.

For routine laboratory weighing where 0.1 mg or 0.01 mg resolution is sufficient, a conventional analytical or semi-microbalance may be more economical and easier to install.

The XPR106H becomes especially useful when the application genuinely benefits from 2–5 µg displayed resolution.

Dual-Range Microgram-Level Weighing Performance

The defining feature of the XPR106H is its dual-range weighing architecture.

The balance provides:

0.002 mg / 2 µg readability through a 41 g fine range, and

0.005 mg / 5 µg readability through its full 120 g weighing capacity.

This means the XPR106H maintains extremely high resolution even when the load exceeds the fine range.

American Instrument Exchange lists repeatability of approximately 0.003 mg / 3 µg and an approximately 4-second stabilization time for this model.

For laboratories performing repetitive high-resolution measurements, this combination provides both sensitivity and practical workflow speed.

Understanding the 41 g Fine Range

The XPR106H's highest resolution is available within its 41 g fine range.

Within this range, the balance displays measurements in increments of just 2 µg.

When the load exceeds the fine-range conditions, the XPR106H continues weighing through its full 120 g capacity at 5 µg readability.

When planning high-resolution procedures, laboratories should consider the entire load placed on the weighing platform rather than sample mass alone.

The weight of filters, sample holders, weighing vessels, containers, and other tare items can determine whether the measurement remains within the fine range.

Using appropriately lightweight vessels may therefore help laboratories take full advantage of the 2 µg range.

Minimum Sample Weight & USP Applications

Minimum sample weight becomes especially important with a balance as sensitive as the XPR106H.

The ability to display 2 µg does not mean that 2 µg is an acceptable quantitative sample weight.

Minimum weight depends primarily on repeatability and the maximum relative measurement uncertainty permitted by the procedure.

The XPR106H incorporates MinWeigh functionality, allowing laboratories to incorporate established minimum-weight requirements into the weighing workflow.

When a sample falls below the defined minimum, the balance can alert the operator that the weighing result may not satisfy the required uncertainty.

For USP, GMP, GLP, or other controlled applications, laboratories should establish minimum sample weight from the actual repeatability of the installed XPR106H under its real operating conditions.

Controlling Drafts & Air Movement

At 2 µg readability, extremely small air movements can affect weighing stability.

The XPR106H incorporates an enclosed draft shield with automatic doors, reducing the influence of surrounding laboratory airflow while allowing convenient access to the weighing chamber.

Automatic door operation also reduces unnecessary physical interaction with the balance.

This can help minimize disturbances caused by vibration, hand movement, and sudden airflow.

The balance should nevertheless be positioned away from HVAC outlets, doors, open windows, fans, and other significant airflow sources.

A stable weighing environment remains essential even when using a sophisticated draft-shield system.

StaticDetect & Electrostatic Error Control

Electrostatic charge can become a significant source of measurement error during microgram-level weighing.

Filters, powders, plastics, glassware, disposable containers, films, and other materials can accumulate static charge during routine handling.

The resulting electrostatic forces may influence the displayed mass even though the actual sample weight has not changed.

The XPR106H incorporates StaticDetect, which identifies electrostatic charge and alerts the operator when static conditions may compromise the weighing result.

This allows technicians to address the problem rather than unknowingly recording a potentially biased measurement.

Depending on the application, additional antistatic equipment, controlled humidity, conductive sample holders, or modified handling procedures may still be appropriate.

SmartGrid & Weighing Stability

The XPR106H incorporates Mettler Toledo's SmartGrid weighing platform.

Unlike a conventional solid weighing pan, SmartGrid reduces the surface area exposed to moving air within the weighing chamber.

This can reduce turbulence and help the balance reach a stable result more quickly after samples are introduced.

SmartGrid is especially useful during repetitive high-resolution weighing where technicians frequently open the draft shield to exchange samples.

The design also allows spilled material to fall away from the primary weighing surface, helping simplify cleaning and inspection.

Automatic Internal Adjustment

The XPR106H incorporates an automatic internal adjustment system that helps maintain weighing performance as laboratory conditions change.

Internal adjustment allows the balance to perform routine adjustment without requiring the operator to manually place an external calibration weight on the weighing platform.

This is particularly useful during high-resolution weighing, where relatively small temperature changes can influence measurement performance.

Automatic adjustment does not eliminate the need for independent verification.

Laboratories operating under USP, GMP, GLP, ISO, or internal quality systems may still require scheduled testing using appropriate traceable external reference weights.

American Instrument Exchange verifies operation of the internal adjustment system and performs external performance testing during refurbishment.

SmartSens Hands-Free Operation

The XPR106H incorporates SmartSens infrared sensors that allow selected balance functions to be performed without physically touching the instrument.

Depending on configuration, operators can use hands-free controls for functions such as opening and closing the automatic draft-shield doors.

At microgram-level resolution, reducing unnecessary physical contact can be beneficial.

Touching the balance can introduce vibration and heat, while repetitive manual operation of draft-shield doors can disturb the air inside the weighing chamber.

SmartSens therefore provides both an ergonomic benefit and a potential improvement in weighing consistency.

StatusLight & LevelControl

The XPR106H incorporates several systems that help users verify whether the balance is ready for reliable weighing.

StatusLight provides a clear visual indication of balance status.

LevelControl monitors balance leveling and warns users when correction is necessary.

These features help reduce the possibility that a measurement will be performed under unsuitable conditions.

This can be especially useful in multi-user laboratories where numerous technicians may use the same instrument throughout the day.

Touchscreen, Methods & Electronic Results

A 7-inch color touchscreen provides access to weighing methods, applications, settings, results, and balance-management functions.

Frequently performed procedures can be stored for future use.

Stored methods can help laboratories standardize weighing procedures and reduce the need for operators to manually configure the balance every time a task is performed.

Electronic result handling can also reduce reliance on handwritten measurements and manual transcription.

For laboratories performing repetitive high-resolution measurements, these features can improve both efficiency and procedural consistency.

Connectivity & LabX Integration

The XPR106H provides USB and Ethernet connectivity for integration with compatible computers, printers, barcode readers, and laboratory systems.

The XPR platform can also be used with Mettler Toledo LabX software.

LabX can support centralized method management, electronic data capture, user controls, traceability, and other laboratory workflow functions.

When appropriately configured and validated, LabX can also support regulated electronic weighing workflows.

This allows the XPR106H to function as part of a larger laboratory data-management system rather than operating only as a standalone balance.

Key Specifications

Choosing Between a Conventional Analytical Balance and the XPR106H

A conventional analytical balance generally provides 0.1 mg / 100 µg readability.

The XPR106H provides resolution as fine as 2 µg, giving it dramatically greater displayed sensitivity.

That additional resolution can be valuable for small samples, reference materials, filters, residues, expensive compounds, and demanding quantitative procedures.

However, greater sensitivity also increases environmental requirements.

The XPR106H requires greater attention to airflow, vibration, static electricity, temperature stability, sample handling, and operator technique than a conventional analytical balance.

Laboratories should therefore select the XPR106H when the measurement requirement genuinely benefits from microgram-level resolution.

XPR106H vs. Conventional 10 µg Semi-Microbalances

Many semi-microbalances provide 0.01 mg / 10 µg readability.

The XPR106H goes substantially further, providing 2 µg readability within its 41 g fine range and 5 µg readability through its full 120 g range.

This gives the XPR106H greater displayed sensitivity than a conventional 10 µg semi-microbalance.

That difference becomes meaningful when laboratories are attempting to reduce sample quantities or measure particularly small changes in mass.

For less demanding applications, a 10 µg semi-microbalance may provide sufficient performance with potentially simpler environmental requirements.

The XPR106H is best suited for procedures where its additional resolution provides a genuine analytical advantage.

XPR106H vs. a Microbalance

The XPR106H approaches microbalance-level sensitivity while retaining substantially greater capacity than many traditional microbalances.

A conventional microbalance may provide 1 µg readability but often has a maximum capacity of only a few grams.

The XPR106H provides 2 µg readability through 41 g and 5 µg readability through 120 g.

A dedicated microbalance remains the better choice when the smallest possible displayed increment is the overriding requirement.

The XPR106H becomes particularly attractive when laboratories need very high resolution combined with practical analytical capacity.

This makes it a useful bridge between semi-micro and microbalance applications.

Refurbishment & Performance Testing

Every used Mettler Toledo XPR106H sold by American Instrument Exchange is inspected, cleaned, refurbished as necessary, calibrated, and tested before shipment.

High-resolution dual-range balances require careful performance testing across meaningful portions of both weighing ranges.

Our technicians evaluate critical weighing characteristics including accuracy, repeatability, linearity, corner-load performance, stability, calibration performance, and reduced span using appropriate reference standards and controlled procedures.

The weighing system, automatic internal adjustment, StaticDetect, SmartGrid, automatic draft shield, SmartSens sensors, touchscreen, StatusLight, LevelControl, interfaces, and other installed functions are inspected and tested for proper operation.

The weighing chamber and accessible components are thoroughly cleaned, and the balance receives a final operational inspection before shipment.

Each refurbished XPR106H includes a 90-day warranty from American Instrument Exchange.

Shipping & Installation Considerations

A balance capable of resolving measurements at only a few micrograms requires careful handling during transportation and installation.

American Instrument Exchange securely prepares the XPR106H for shipment to protect its weighing system, SmartGrid, automatic draft shield, touchscreen, sensors, and electronic components.

Once received, the balance should be installed on a rigid, stable, vibration-resistant weighing table away from HVAC outlets, doors, direct sunlight, centrifuges, shakers, pumps, compressors, and other significant sources of airflow or vibration.

The balance should be properly leveled and allowed to acclimate to the laboratory environment before critical measurements begin.

For demanding or regulated applications, installation should be followed by appropriate calibration verification, repeatability testing, minimum-weight determination, or qualification according to the laboratory's quality procedures.

Related Laboratory Equipment

American Instrument Exchange maintains an extensive inventory of used and refurbished laboratory balances, including analytical balances, semi-micro balances, microbalances, and precision balances for applications ranging from routine sample preparation to high-resolution quantitative analysis.

Labs developing complete analytical or sample-preparation workflows can also source centrifuges, water baths, incubators, laboratory refrigerators, laboratory freezers, and other refurbished laboratory equipment from American Instrument Exchange.

Mettler Toledo XPR106H Dual-Range Analytical Balance FAQs

What is the maximum capacity of the Mettler Toledo XPR106H?

The XPR106H has a maximum weighing capacity of 120 g and a 41 g fine weighing range.

What is the readability of the XPR106H?

The balance provides 0.002 mg / 2 µg readability through its 41 g fine range and 0.005 mg / 5 µg readability through its full 120 g capacity.

Is the XPR106H an analytical balance or semi-microbalance?

The XPR106H is best described as a high-resolution dual-range analytical balance. Its 2–5 µg readability is substantially finer than the 0.1 mg readability of a conventional analytical balance and even finer than many 10 µg semi-microbalances.

Does the XPR106H provide 2 µg readability throughout its entire capacity?

No. The highest 2 µg readability applies within the 41 g fine range. Across the full 120 g weighing range, readability is 5 µg.

What is StaticDetect?

StaticDetect helps identify electrostatic charge that can interfere with high-resolution weighing. This is particularly useful for powders, filters, plastics, films, and other materials prone to static buildup.

Does the XPR106H have automatic draft-shield doors?

Yes. The XPR106H incorporates automatic draft-shield doors, reducing the amount of manual interaction required during repetitive weighing.

What is MinWeigh?

MinWeigh allows minimum-weight requirements to be incorporated into the weighing process so users can identify when a sample falls below an established quantitative threshold.

Can the XPR106H detect whether it is level?

Yes. LevelControl monitors balance leveling and alerts the operator when correction is necessary.

What is SmartSens?

SmartSens uses infrared sensors to allow selected operations to be performed without touching the balance, including hands-free control of compatible functions.

Can the XPR106H connect to LabX?

Yes. The XPR platform can be integrated with Mettler Toledo LabX for electronic data capture, method management, traceability, user controls, and other laboratory workflow capabilities when appropriately configured.

Why purchase a refurbished Mettler Toledo XPR106H?

A refurbished XPR106H provides laboratories with 2 µg fine-range readability, 120 g capacity, StaticDetect, SmartGrid, MinWeigh, automatic draft-shield doors, SmartSens, touchscreen operation, and advanced electronic workflow capabilities at a lower acquisition cost than comparable new high-resolution weighing systems. American Instrument Exchange tests, calibrates, cleans, and refurbishes each balance before shipment and provides a 90-day warranty.