Mettler Toledo XSR10001L Precision Balance – Used & Refurbished
The Mettler Toledo XSR10001L Precision Balance is a high-capacity laboratory balance designed for fast, dependable weighing of larger samples, containers, formulations, and preparation vessels. Combining a 10.1 kg maximum capacity with 0.1 g readability, the XSR10001L provides an excellent balance between kilogram-scale weighing capability and laboratory-grade precision.
Available used and refurbished from American Instrument Exchange, the Mettler Toledo XSR10001L incorporates a large 360 × 280 mm weighing platform, FACT automatic internal adjustment, a 4.5-inch color touchscreen, integrated weighing methods, electronic results management, and extensive connectivity. It is particularly well suited for pharmaceutical, biotechnology, chemical, formulation, food and beverage, materials science, manufacturing, and quality-control laboratories.
Each balance is inspected, cleaned, calibrated, and tested for weighing performance before shipment and includes a 90-day warranty from American Instrument Exchange.
Key Features
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10.1 kg / 10,100 g maximum weighing capacity
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100 mg / 0.1 g readability
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Repeatability limit of 80 mg / 0.08 g
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Typical repeatability of approximately 40 mg / 0.04 g
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Linearity deviation limit of ±200 mg / ±0.2 g
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Typical linearity deviation of approximately 60 mg / 0.06 g
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Typical USP minimum weight of approximately 82 g
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Typical minimum weight of approximately 8.2 g at U=1%, k=2
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Approximately 1.5-second settling time
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FACT automatic internal adjustment
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Large 360 × 280 mm weighing platform
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4.5-inch color TFT touchscreen
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Integrated method library
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Results notepad
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Leveling guidance
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Password protection
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USB, Ethernet/LAN, RS232, and optional Bluetooth connectivity
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LabX compatible
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Supports 21 CFR Part 11-compliant weighing workflows when appropriately configured
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Standard XSR10001L is not Legal for Trade
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Used, refurbished, calibrated, and tested by American Instrument Exchange
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90-day warranty included
Overview
The Mettler Toledo XSR10001L belongs to the large-platform family of Excellence XSR precision balances.
Its 10.1 kg capacity and 0.1 g readability make it particularly useful for laboratories that routinely work with larger samples and containers but do not require the finer 0.01 g resolution provided by higher-resolution precision balances.
The XSR10001L provides substantially more usable weighing space than a conventional compact precision balance. Its large platform can accommodate bottles, beakers, preparation vessels, containers, trays, and bulky samples that may be difficult to position on smaller balances.
The 10.1 kg capacity also provides substantial allowance for container tare weight.
Beyond basic weighing, the XSR platform incorporates touchscreen operation, stored weighing methods, electronic result handling, automatic internal adjustment, and connectivity for integration into modern laboratory workflows.
This combination makes the XSR10001L a versatile instrument for routine sample preparation, formulation, quality control, research, and production-support applications.
Common Applications
The Mettler Toledo XSR10001L is well suited for media and buffer preparation, formulation, reagent weighing, solution preparation, ingredient weighing, sample preparation, component weighing, quality control, check weighing, percentage weighing, and general laboratory measurements.
Pharmaceutical and biotechnology laboratories can use the XSR10001L for preparing buffers, media, formulations, excipients, reagents, and process-development materials.
Chemical laboratories can use the balance for solution preparation, compound weighing, mixture preparation, formulation development, and routine quantitative procedures.
Food and beverage, cosmetics, materials science, environmental, manufacturing, and quality-control laboratories can also use the XSR10001L for ingredient weighing, sample preparation, product development, batch preparation, and general laboratory weighing.
Its large platform is especially useful when a sample is not exceptionally heavy but its container has a relatively large footprint.
Ideal Laboratory Types
The XSR10001L is a strong choice for pharmaceutical, biotechnology, chemical, formulation, food and beverage, cosmetics, materials science, environmental, manufacturing, process-development, industrial research, and quality-control laboratories.
It is particularly useful in facilities where a conventional 3–6 kg precision balance does not provide enough capacity for routine work.
With 10.1 kg available, technicians can work directly with larger bottles, beakers, containers, and preparation vessels without approaching the balance's capacity limit during normal procedures.
At the same time, 0.1 g readability provides substantially finer resolution than a general-purpose industrial scale.
This makes the XSR10001L a practical laboratory workhorse for gram-to-kilogram weighing.
High-Capacity Precision Weighing Performance
The Mettler Toledo XSR10001L provides 100 mg, or 0.1 g, readability throughout its 10.1 kg weighing range.
Mettler Toledo specifies a repeatability limit of 80 mg, with typical repeatability of approximately 40 mg under appropriate operating conditions.
Linearity deviation is specified at a limit of ±200 mg, with typical linearity deviation of approximately 60 mg.
The balance also provides an approximately 1.5-second settling time.
This combination supports rapid, consistent measurements during repetitive weighing, formulation, and preparation procedures.
For laboratories primarily working with quantities ranging from several dozen grams to several kilograms, the XSR10001L provides a useful combination of capacity, speed, and measurement resolution.
Minimum Sample Weight & USP Applications
Mettler Toledo specifies a typical USP minimum sample weight of approximately 82 g for the XSR10001L under stated reference conditions.
The manufacturer also specifies a typical minimum weight of approximately 8.2 g at U=1%, k=2.
These figures illustrate the important difference between readability and minimum sample weight.
Although the XSR10001L displays measurements in 0.1 g increments, the smallest quantity that can be weighed quantitatively depends on the measurement uncertainty permitted by the laboratory's procedure.
Repeatability, installation conditions, environmental stability, calibration status, and individual balance performance all influence minimum weight.
For USP, GMP, GLP, or other controlled applications, laboratories should establish minimum sample weight based on the actual performance of the installed XSR10001L rather than treating 0.1 g readability as its minimum quantitative sample size.
Controlling Vibration & Environmental Influences
The XSR10001L is less environmentally sensitive than an analytical, semi-micro, or 0.01 g high-resolution precision balance, making it relatively easy to incorporate into routine laboratory environments.
Proper installation nevertheless contributes to reliable performance.
Vibration, unstable work surfaces, strong airflow, rapid temperature changes, and improper leveling can affect weighing results.
The balance should be installed on a rigid, stable, level work surface away from significant vibration sources such as centrifuges, shakers, pumps, compressors, and other moving laboratory equipment.
Because the XSR10001L can support more than 10 kg, the laboratory bench should also remain rigid when the balance is carrying heavier containers and samples.
Built-in leveling guidance assists users in maintaining proper balance setup.
Calibration & FACT Automatic Internal Adjustment
The XSR10001L incorporates FACT automatic internal adjustment.
FACT uses the balance's internal reference system to perform adjustment automatically, helping maintain weighing performance as operating conditions change.
This is especially convenient on a high-capacity balance because manual adjustment can otherwise require handling relatively large external calibration weights.
Automatic internal adjustment does not eliminate the need for independent performance verification.
Laboratories operating under GLP, GMP, USP, ISO, or internal quality systems may require routine testing with appropriate traceable external reference weights.
American Instrument Exchange calibrates and evaluates each refurbished XSR10001L before shipment and verifies proper operation of the FACT internal adjustment system.
Large Weighing Platform & Container Handling
The XSR10001L incorporates a large 360 × 280 mm weighing platform.
This provides substantially more usable working area than the weighing pan found on many compact precision balances.
Bottles, beakers, formulation vessels, sample containers, trays, and other bulky objects can be positioned directly on the platform.
The 10.1 kg maximum capacity also provides enough headroom to accommodate substantial container tare weights.
A technician preparing a buffer, media formulation, solution, or other laboratory mixture can place the final preparation vessel directly on the balance, tare it, and add ingredients sequentially.
This direct-to-container weighing approach can simplify laboratory preparation procedures, reduce unnecessary transfers, and decrease the potential for material loss during handling.
Touchscreen Operation & Integrated Methods
The XSR10001L uses a 4.5-inch color TFT touchscreen that provides access to weighing functions, stored methods, settings, and results.
Frequently performed procedures can be saved in the integrated method library.
Method storage can help laboratories standardize repetitive weighing procedures and maintain more consistent operation between users.
Instead of manually configuring the balance each time a particular procedure is performed, technicians can access the appropriate stored method and begin work using predefined parameters.
This can be especially useful in shared laboratories, quality-control departments, and environments where weighing procedures are performed repeatedly by multiple operators.
Results Management & Electronic Documentation
The XSR10001L incorporates an integrated results notepad that automatically records weighing results and associated task information.
Electronic result handling can reduce reliance on handwritten measurements and manual transcription.
Results can be transferred to compatible computer systems using the balance's communication interfaces, helping laboratories create more efficient documentation workflows.
For routine research laboratories, this provides a convenient method of transferring weighing data.
For regulated environments, electronic documentation can form part of a broader controlled data-management system.
Connectivity & LabX Integration
The XSR10001L provides extensive connectivity for integration with laboratory peripherals and information systems.
Interfaces include USB, Ethernet/LAN, RS232, and optional Bluetooth connectivity.
Compatible computers, printers, barcode readers, and other peripherals can therefore be incorporated into weighing workflows.
The XSR platform is also compatible with Mettler Toledo LabX software.
When appropriately configured and validated, LabX can support 21 CFR Part 11-compliant weighing workflows, including electronic documentation, centralized methods, controlled data transfer, traceability, and other data-integrity functions.
This makes the XSR10001L suitable for both straightforward research weighing and more sophisticated pharmaceutical or quality-controlled workflows.
Key Specifications
| Specification |
Mettler Toledo XSR10001L |
| Balance Type |
High-Capacity Precision / Toploading Balance |
| Maximum Capacity |
10.1 kg / 10,100 g |
| Readability |
100 mg / 0.1 g |
| Repeatability Limit |
80 mg / 0.08 g |
| Typical Repeatability |
Approx. 40 mg / 0.04 g |
| Linearity Deviation Limit |
±200 mg / ±0.2 g |
| Typical Linearity Deviation |
Approx. 60 mg / 0.06 g |
| Typical USP Minimum Weight |
Approx. 82 g |
| Typical Minimum Weight (U=1%, k=2) |
Approx. 8.2 g |
| Settling Time |
Approx. 1.5 seconds |
| Adjustment |
Internal / automatic FACT |
| Weighing Pan |
360 × 280 mm |
| Overall Dimensions |
360 mm W × 412 mm D × 122 mm H |
| Display |
4.5-inch color TFT touchscreen |
| Leveling Guidance |
Yes |
| Method Library |
Yes |
| Results Notepad |
Yes |
| Password Protection |
Yes |
| Connectivity |
USB, Ethernet/LAN, RS232; optional Bluetooth |
| LabX Compatible |
Yes |
| 21 CFR Part 11 Support |
Yes, when appropriately configured with LabX |
| Legal for Trade |
No – standard XSR10001L |
Choosing Between a 10 kg and 16 kg Precision Balance
The XSR10001L provides 10.1 kg maximum capacity, making it suitable for a broad range of laboratory preparation and formulation procedures.
For laboratories that routinely work with larger vessels or heavier batches, a 16 kg balance such as the XSR16001L may provide additional working headroom.
Both models provide 0.1 g readability, so moving to the larger balance does not require sacrificing displayed resolution.
The decision should therefore be based primarily on the combined weight of the laboratory's largest expected container and its contents.
If working loads remain comfortably below 10 kg, the XSR10001L provides substantial capacity.
If procedures routinely approach the 10 kg limit, selecting a 16 kg model can prevent operators from working too close to maximum capacity and provide room for future scale-up.
XSR10001L vs. XSR10002S
The XSR10001L and XSR10002S occupy distinctly different positions despite their similar model names.
The XSR10001L provides 10.1 kg capacity with 0.1 g readability.
The XSR10002S also provides approximately 10.1 kg capacity but increases resolution to 0.01 g.
The XSR10002S therefore provides ten times finer displayed resolution.
That additional resolution is valuable for demanding formulation, quantitative sample preparation, and procedures involving smaller ingredient additions.
The XSR10001L is better suited for larger-scale routine preparation where 0.1 g resolution is sufficient.
The difference is also reflected in typical USP minimum weight. The XSR10001L has a typical USP minimum weight of approximately 82 g, while a 0.01 g XSR balance can support substantially smaller quantitative sample sizes under appropriate conditions.
Laboratories should therefore choose between these models based on the smallest quantity they need to measure reliably, not simply their similar maximum capacities.
XSR10001L vs. Older XS Large-Platform Balances
The XSR10001L represents a newer generation of Mettler Toledo Excellence precision-balance technology compared with the earlier XS series.
Both generations provide reliable laboratory weighing, internal adjustment, large weighing platforms, and advanced applications.
The XSR platform adds a newer touchscreen interface, integrated method storage, electronic results management, improved connectivity, password protection, and enhanced LabX compatibility.
An older refurbished XS balance can still provide excellent weighing performance when straightforward laboratory weighing is the primary requirement.
The XSR10001L becomes particularly attractive when method standardization, electronic documentation, connectivity, and modern laboratory workflow integration are important.
Manufacturer Notes
Mettler Toledo discontinued the XSR10001L in February 2024.
The manufacturer identifies the MX12001L as its replacement model.
Discontinued status does not prevent the XSR10001L from remaining a useful laboratory instrument. For laboratories that do not require the newest balance platform, a properly tested and calibrated refurbished XSR10001L can provide high-capacity Excellence-series weighing performance at a substantially lower acquisition cost than purchasing a current-generation balance.
Availability of parts, accessories, software compatibility, and long-term manufacturer support should be considered when purchasing discontinued laboratory equipment.
Refurbishment & Performance Testing
Every used Mettler Toledo XSR10001L sold by American Instrument Exchange is inspected, cleaned, refurbished as necessary, calibrated, and tested before shipment.
Our technicians use appropriate calibration weights to evaluate critical performance characteristics including accuracy, repeatability, linearity, corner-load tolerances, stability, and reduced span at or near full capacity.
Testing a 10.1 kg precision balance requires meaningful evaluation across its working range rather than simply confirming response to a small reference weight.
The weighing system, FACT automatic internal adjustment, touchscreen, controls, leveling functions, weighing platform, interfaces, and other installed features are also inspected and tested for proper operation.
The balance is thoroughly cleaned and receives a final operational inspection before shipment.
Each refurbished XSR10001L includes a 90-day warranty from American Instrument Exchange.
Shipping & Installation Considerations
American Instrument Exchange securely prepares the XSR10001L for shipment to protect its weighing system, large weighing platform, touchscreen, and electronic components.
Once received, the balance should be installed on a rigid, stable, level, vibration-resistant laboratory work surface capable of supporting the balance and its maximum intended load.
The instrument should be positioned away from strong airflow, significant vibration, and rapid temperature changes whenever practical.
After installation, the XSR10001L should be allowed to acclimate to the laboratory environment before final adjustment, calibration verification, and critical quantitative weighing begins.
For regulated applications, installation should be followed by appropriate calibration, performance verification, minimum-weight determination, or qualification according to the laboratory's quality system.
Related Laboratory Equipment
American Instrument Exchange maintains an extensive inventory of used and refurbished laboratory balances, including analytical balances, semi-micro balances, microbalances, and precision balances for applications ranging from routine sample preparation to high-resolution quantitative analysis.
Labs developing complete analytical or sample-preparation workflows can also source centrifuges, water baths, incubators, laboratory refrigerators, laboratory freezers, and other refurbished laboratory equipment from American Instrument Exchange.
Mettler Toledo XSR10001L Precision Balance FAQs
What is the maximum capacity of the Mettler Toledo XSR10001L?
The XSR10001L has a maximum weighing capacity of 10.1 kg, or 10,100 g.
What is the readability of the XSR10001L?
The XSR10001L provides 100 mg, or 0.1 g, readability throughout its 10.1 kg weighing range.
What is the typical repeatability of the XSR10001L?
Mettler Toledo specifies typical repeatability of approximately 40 mg, with a repeatability limit of 80 mg.
What is the typical USP minimum weight?
Mettler Toledo specifies a typical USP minimum weight of approximately 82 g under reference conditions. Actual minimum weight should be determined according to the performance of the individual installed balance and the laboratory's measurement uncertainty requirements.
How quickly does the XSR10001L stabilize?
The XSR10001L has a typical settling time of approximately 1.5 seconds, supporting efficient repetitive weighing and preparation procedures.
Does the XSR10001L have automatic internal adjustment?
Yes. The XSR10001L incorporates FACT automatic internal adjustment using an internal reference system.
How large is the XSR10001L weighing platform?
The XSR10001L has a large 360 × 280 mm weighing platform, providing ample room for bottles, beakers, containers, preparation vessels, trays, and bulky samples.
What is the difference between the XSR10001L and XSR10002S?
Both models provide approximately 10.1 kg capacity. The XSR10001L provides 0.1 g readability, while the XSR10002S provides 0.01 g readability. The XSR10002S therefore offers ten times finer displayed resolution.
Is the XSR10001L Legal for Trade?
The standard XSR10001L is not Legal for Trade and is not an approved balance configuration.
Is the Mettler Toledo XSR10001L discontinued?
Yes. Mettler Toledo discontinued the XSR10001L in February 2024 and identifies the MX12001L as its current replacement.
Why purchase a refurbished Mettler Toledo XSR10001L?
A refurbished XSR10001L provides laboratories with 10.1 kg capacity, 0.1 g readability, FACT automatic internal adjustment, a large weighing platform, touchscreen operation, integrated methods, electronic results management, and modern connectivity at a lower acquisition cost than comparable new equipment. American Instrument Exchange tests, calibrates, cleans, and refurbishes each balance before shipment and provides a 90-day warranty.
