Mettler Toledo XSE105DU Dual-Range Semi-Micro Analytical Balance
Shipping
All products ship from our 30,000 sq. ft. Haverhill, MA warehouse
Shipping
All products ship from our 30,000 sq. ft. Haverhill, MA warehouse
The Mettler Toledo XSE105DU Dual-Range Semi-Micro Analytical Balance combines high-resolution semi-micro weighing with the flexibility of a conventional analytical balance. Its dual-range weighing system provides 0.01 mg / 10 µg readability through a 41 g fine range and 0.1 mg readability through its full 120 g capacity.
Available used and refurbished from American Instrument Exchange, the XSE105DU belongs to Mettler Toledo's Excellence analytical balance family and incorporates SmartGrid weighing technology, proFACT Advanced automatic internal adjustment, StatusLight balance monitoring, MinWeigh functionality, graphical leveling guidance, a color touchscreen, password-protected user access, built-in applications, and electronic connectivity.
The dual-range architecture makes the XSE105DU especially useful for laboratories that occasionally need semi-micro resolution but also want the broader working capacity and faster routine operation of a traditional analytical balance.
Each XSE105DU is inspected, cleaned, calibrated, and tested for weighing performance before shipment and includes a 90-day warranty from American Instrument Exchange.
41 g fine-range capacity
0.01 mg / 10 µg fine-range readability
120 g full-range capacity
0.1 mg full-range readability
Typical repeatability of approximately 0.01 mg
Typical USP minimum sample weight of approximately 20 mg
Linearity deviation of ±0.2 mg
Approximately 1.5-second settling time
proFACT Advanced automatic internal adjustment
SmartGrid weighing pan
73 × 78 mm weighing pan
Enclosed analytical draft shield
StatusLight balance-status monitoring
MinWeigh minimum-weight functionality
Graphical leveling guidance
Color touchscreen
Password protection for multiple users
Built-in RS232 interface
LabX compatible
Die-cast aluminum housing
Used, refurbished, calibrated, and tested by American Instrument Exchange
90-day warranty included
The Mettler Toledo XSE105DU is a dual-range analytical balance designed to give laboratories access to semi-micro resolution without limiting the instrument to a relatively small maximum capacity.
Within its 41 g fine range, the balance provides 0.01 mg / 10 µg readability. This is ten times finer than the 0.1 mg readability associated with a conventional analytical balance.
When the weighing load extends beyond the fine range, the XSE105DU continues to operate through its full 120 g capacity at 0.1 mg readability.
This arrangement gives laboratories two useful performance levels in one instrument.
Small analytical samples can be weighed at semi-micro resolution, while heavier samples and tare vessels can still be accommodated using conventional analytical resolution.
For laboratories whose methods do not require 10 µg resolution for every measurement, this can be a practical alternative to a single-range semi-microbalance.
The Mettler Toledo XSE105DU is well suited for pharmaceutical formulation, reference-standard preparation, quantitative chemical analysis, gravimetric analysis, reagent weighing, filter weighing, residue determination, sample preparation, quality control, density determination, percentage weighing, differential weighing, and research applications.
Pharmaceutical and biotechnology laboratories can use the fine range for reference standards, active ingredients, potent compounds, and small formulation quantities while retaining the larger analytical range for heavier samples and vessels.
Chemical laboratories can use the XSE105DU for quantitative analysis, solution preparation, standards preparation, and research.
Environmental laboratories may use the balance for filters, residues, and gravimetric measurements where the 10 µg fine range provides additional sensitivity.
The XSE105DU is particularly well suited for pharmaceutical, biotechnology, chemical, environmental, analytical testing, contract research, academic, materials science, quality-control, and R&D laboratories.
It is especially useful in laboratories that perform a mixture of conventional analytical and semi-micro weighing.
Rather than maintaining separate balances for every application, the XSE105DU allows technicians to perform high-resolution measurements within the 41 g fine range and conventional analytical weighing through 120 g.
This versatility can make it a strong general-purpose balance for laboratories with varying sample sizes and uncertainty requirements.
The defining feature of the XSE105DU is its dual-range weighing architecture.
Within the fine range, the balance provides:
41 g maximum capacity at 0.01 mg / 10 µg readability.
Across the full range, it provides:
120 g maximum capacity at 0.1 mg readability.
Mettler Toledo specifies typical repeatability of approximately 0.01 mg, a linearity deviation of ±0.2 mg, and an approximately 1.5-second settling time.
This configuration gives laboratories access to semi-micro resolution when needed without requiring every measurement to be performed at the highest sensitivity.
The XSE105DU's highest resolution is available within its 41 g fine range.
When planning a high-resolution procedure, the laboratory must consider the total load placed on the weighing pan, including the sample and tare vessel.
A 10 g sample in a 15 g weighing vessel remains comfortably within the fine range.
A 10 g sample in a 50 g container does not.
This means container selection can directly affect whether the balance operates at 10 µg or 0.1 mg readability.
For laboratories that frequently use the fine range, lightweight weighing vessels, filters, boats, vials, or ErgoClip accessories may help preserve the highest available resolution.
Mettler Toledo specifies a typical USP minimum sample weight of approximately 20 mg for the XSE105DU under reference conditions.
This value illustrates the difference between readability and minimum quantitative sample weight.
The XSE105DU can display increments of 0.01 mg within its fine range, but that does not mean a 0.01 mg sample can be weighed quantitatively within a specified relative uncertainty.
Minimum sample weight depends primarily on repeatability and the uncertainty requirement of the procedure.
For USP, GMP, GLP, or other controlled applications, laboratories should establish minimum weight from the actual repeatability of the installed balance under its real operating conditions.
The XSE105DU includes MinWeigh functionality to help laboratories incorporate established minimum-weight requirements into routine procedures.
Once an appropriate minimum sample weight has been determined, MinWeigh can alert the operator when the sample quantity falls below the defined threshold.
This can be particularly useful in laboratories where multiple users perform small-sample weighing and may not otherwise recognize that a sample falls below an established quantitative limit.
MinWeigh should be treated as a workflow tool rather than a substitute for determining the correct minimum weight through appropriate repeatability testing.
The XSE105DU incorporates Mettler Toledo's SmartGrid weighing pan.
The grid-style design reduces the surface area exposed to moving air compared with a conventional solid weighing pan.
This helps reduce turbulence inside the weighing chamber and can improve stabilization after samples are introduced.
SmartGrid can be especially useful during repetitive fine-range weighing, where small air disturbances become more visible at 10 µg resolution.
Mettler Toledo also offers ErgoClip accessories designed to secure different vessel shapes directly on the SmartGrid platform.
At 10 µg readability, environmental conditions can have a significant influence on weighing stability.
The XSE105DU incorporates an enclosed analytical draft shield to protect the weighing area from normal laboratory airflow.
The balance should still be positioned away from HVAC outlets, open windows, frequently used doors, fans, and other significant air currents.
Temperature gradients can also affect weighing performance.
Samples transferred from refrigerators, freezers, ovens, incubators, or other temperature-controlled equipment should be allowed to approach laboratory temperature before critical quantitative measurements whenever the procedure allows.
The XSE105DU should be installed on a rigid, stable, level weighing surface away from significant vibration sources.
Centrifuges, shakers, pumps, compressors, refrigerators, freezers, and other laboratory equipment can transmit vibration through benches, floors, and building structures.
Static electricity may also influence weighing results, particularly when working with powders, filters, plastic containers, films, glassware, and other materials that readily accumulate charge.
Appropriate antistatic accessories, conductive sample holders, grounding techniques, or humidity management may be useful when electrostatic effects become significant.
The XSE105DU incorporates proFACT Advanced automatic internal adjustment.
This system uses internal reference weights to perform automatic adjustment when defined time or temperature conditions indicate that adjustment is required.
Automatic internal adjustment is particularly valuable for high-resolution weighing because relatively small environmental changes can influence balance sensitivity.
proFACT Advanced helps maintain consistent performance without requiring the operator to manually place an external calibration weight on the pan every time routine adjustment is needed.
Independent verification with appropriate external reference weights may still be required under USP, GMP, GLP, ISO, or laboratory-specific quality procedures.
The XSE105DU incorporates Mettler Toledo's StatusLight system to give users an immediate visual indication of balance status.
The system uses color-coded indications to help operators recognize whether the instrument is ready for weighing or whether an issue requires attention.
This can be particularly useful in multi-user laboratories where several technicians may operate the same balance throughout the day.
StatusLight works together with the balance's leveling and test-management functions to provide users with a clearer indication of instrument readiness before measurements begin.
Correct leveling is essential for high-resolution weighing.
The XSE105DU provides graphical leveling guidance to help operators recognize when the balance requires adjustment.
This is particularly useful after the balance has been moved, cleaned, repositioned, or subjected to changes in the work surface.
At semi-micro resolution, proper leveling should be considered part of routine balance preparation rather than an occasional maintenance task.
The XSE105DU incorporates a color touchscreen interface for access to weighing applications, balance settings, system information, and stored procedures.
The AIE configuration also supports password protection for multiple users.
User-specific access can be valuable in multi-user laboratories where technicians require different levels of permission or where balance settings should be protected from unauthorized changes.
The touchscreen interface also simplifies navigation through weighing applications and quality-control functions.
The XSE105DU includes an integrated RS232 interface for connection to compatible computers, printers, and laboratory peripherals.
The XSE platform is also compatible with Mettler Toledo LabX software.
LabX can support electronic data transfer, calculations, result storage, workflow guidance, traceability, and other laboratory data-management functions when appropriately configured.
Electronic transfer of results can reduce manual transcription and improve consistency in laboratories processing large numbers of analytical measurements.
| Specification | Mettler Toledo XSE105DU |
|---|---|
| Balance Type | Dual-Range Semi-Micro Analytical Balance |
| Fine-Range Capacity | 41 g |
| Fine-Range Readability | 0.01 mg / 10 µg |
| Full-Range Capacity | 120 g |
| Full-Range Readability | 0.1 mg |
| Typical Repeatability | Approx. 0.01 mg |
| Repeatability Limit at 100 g | 0.1 mg |
| Repeatability Limit at 5 g | 0.05 mg |
| Fine-Range Repeatability Limit at 5 g | 0.02 mg |
| Typical USP Minimum Weight | Approx. 20 mg |
| Linearity Deviation | ±0.2 mg |
| Settling Time | Approx. 1.5 seconds |
| Adjustment | Internal / proFACT Advanced |
| Weighing Pan | SmartGrid |
| Pan Dimensions | 73 × 78 mm |
| Draft Shield | Enclosed analytical draft shield |
| Status Monitoring | StatusLight |
| Minimum Weight Function | MinWeigh |
| Leveling | Graphical leveling guidance |
| Display | Color touchscreen |
| Standard Interface | RS232 |
| LabX Compatible | Yes |
| Housing | Die-cast aluminum |
| Overall Dimensions | 263 mm W × 482 mm D × 322 mm H |
| Legal for Trade | No, standard XSE105DU |
| Warranty | 90 days from American Instrument Exchange |
A conventional analytical balance typically provides 0.1 mg readability.
A single-range semi-microbalance typically provides 0.01 mg / 10 µg readability throughout its capacity.
The XSE105DU provides a combination of both.
Within the 41 g fine range, it performs like a semi-microbalance with 10 µg readability.
Above that range, it continues weighing through 120 g at conventional 0.1 mg analytical resolution.
This makes the XSE105DU particularly attractive when high-resolution weighing is required for some procedures but not every sample.
A single-range semi-microbalance may be preferable when 10 µg readability must remain available regardless of tare weight or total load.
The XSE105DU and XPE105 provide different approaches to semi-micro weighing.
The XSE105DU provides 10 µg readability within a 41 g fine range and 0.1 mg readability through its full 120 g capacity.
The XPE105 provides 10 µg readability throughout its entire 120 g capacity.
The XPE105 is therefore the better choice when semi-micro resolution is routinely required with total loads above 41 g.
The XSE105DU can be more than sufficient when most high-resolution samples remain within the 41 g fine range and conventional analytical resolution is acceptable for larger loads.
The XSE105DU and XS105DU have very similar core weighing specifications.
Both provide a 41 g fine range with 0.01 mg readability and a 120 g full range with 0.1 mg readability.
The primary difference is generation and workflow capability.
The XSE105DU belongs to the newer XSE Excellence generation and adds features such as StatusLight, enhanced MinWeigh functionality, graphical leveling guidance, more advanced user management, and expanded laboratory workflow capabilities.
A properly refurbished XS105DU remains a capable dual-range semi-microbalance for laboratories primarily concerned with core weighing performance.
The XSE105DU is particularly attractive when operator guidance, quality-control functions, and electronic workflow integration are also important.
The XSE105DU and XSE104 share the same 120 g maximum capacity but use different weighing architectures.
The XSE104 is a conventional single-range analytical balance providing 0.1 mg readability throughout its capacity.
The XSE105DU adds a 41 g fine range with 0.01 mg / 10 µg readability.
For routine analytical weighing where 0.1 mg resolution is sufficient, the XSE104 may be entirely appropriate.
The XSE105DU becomes more valuable when the laboratory occasionally requires semi-micro sensitivity for smaller samples.
Dual-range balances provide a practical compromise between maximum resolution and working capacity.
Not every laboratory sample requires the highest available sensitivity.
By offering 10 µg readability within a useful 41 g fine range and 0.1 mg readability through 120 g, the XSE105DU can support both high-resolution and routine analytical procedures.
This can make the balance particularly useful in laboratories where methods vary substantially from one sample to another.
The key is understanding the fine-range limit and selecting tare vessels appropriately when 10 µg readability is required.
Every used Mettler Toledo XSE105DU sold by American Instrument Exchange is inspected, cleaned, refurbished as necessary, calibrated, and tested before shipment.
Our technicians use appropriate calibration weights to evaluate accuracy, repeatability, linearity, corner-load performance, stability, reduced span, and performance across appropriate portions of both weighing ranges.
The weighing system, proFACT Advanced automatic internal adjustment, SmartGrid pan, StatusLight, MinWeigh, leveling system, touchscreen, draft shield, interfaces, and other installed functions are inspected and tested for proper operation.
The weighing chamber, draft-shield panels, SmartGrid pan, and accessible components are thoroughly cleaned before the balance receives a final operational inspection.
Each refurbished XSE105DU includes a 90-day warranty from American Instrument Exchange.
A dual-range semi-microbalance requires careful transportation and installation.
American Instrument Exchange securely prepares the XSE105DU for shipment to protect its weighing system, SmartGrid pan, glass draft shield, touchscreen, and electronic components.
Once received, the balance should be installed on a rigid, stable, vibration-resistant weighing table away from HVAC outlets, doors, direct sunlight, centrifuges, shakers, pumps, compressors, and other significant sources of vibration or airflow.
The balance should be properly leveled and allowed to acclimate to the laboratory environment before critical quantitative measurements begin.
For regulated or particularly demanding applications, installation should be followed by appropriate calibration verification, repeatability testing, minimum-weight determination, or qualification according to the laboratory's quality procedures.
American Instrument Exchange maintains an extensive inventory of used and refurbished laboratory balances, including analytical balances, semi-micro balances, microbalances, and precision balances for applications ranging from routine sample preparation to high-resolution quantitative analysis.
Labs developing complete analytical or sample-preparation workflows can also source centrifuges, water baths, incubators, laboratory refrigerators, laboratory freezers, and other refurbished laboratory equipment from American Instrument Exchange.
The XSE105DU has a full-range maximum capacity of 120 g and a 41 g high-resolution fine range.
The XSE105DU provides 0.01 mg / 10 µg readability within its 41 g fine range and 0.1 mg readability through its full 120 g capacity.
Mettler Toledo classifies the XSE105DU within its analytical balance family. Because its fine range provides 10 µg readability, it can also accurately be described as a dual-range semi-micro analytical balance.
The XSE105DU is a dual-range balance. Its highest resolution is available within a 41 g fine range, while its full analytical range extends to 120 g.
Mettler Toledo specifies typical repeatability of approximately 0.01 mg under reference conditions.
Mettler Toledo specifies a typical USP minimum sample weight of approximately 20 mg under reference conditions.
The XSE105DU has an approximately 1.5-second settling time.
Yes. The XSE105DU incorporates proFACT Advanced automatic internal adjustment.
StatusLight provides an immediate visual indication of balance status, helping users recognize whether the instrument is ready for weighing or whether attention is required.
MinWeigh allows an established minimum sample weight to be incorporated into the weighing workflow and can alert the user when the net sample falls below the defined threshold.
The XSE105DU provides 10 µg readability within a 41 g fine range and 0.1 mg readability through 120 g. The XPE105 provides 10 µg readability throughout its entire 120 g capacity.
Both have similar 41/120 g dual-range specifications. The XSE105DU is a newer-generation platform with additional quality-control, operator-guidance, and workflow-management capabilities.
Yes. The XSE platform is compatible with Mettler Toledo LabX software for electronic data handling, workflow guidance, calculations, result storage, and traceability when appropriately configured.
A refurbished XSE105DU provides both 10 µg semi-micro resolution and 120 g analytical capacity in one balance, along with proFACT Advanced, SmartGrid, StatusLight, MinWeigh, touchscreen operation, electronic connectivity, and advanced workflow features. American Instrument Exchange tests, calibrates, cleans, and refurbishes each balance before shipment and provides a 90-day warranty.
CLICK HERE to see a video of the Mettler Toledo XSE 105DU on our YouTube channel.
Yes, all equipment from American Instrument Exchange comes with a warranty.
Used/reconditioned/refurbished equipment is tested to make sure it operates to the manufacturer's specifications and comes with a 90-day warranty (unless otherwise noted). New equipment comes with a warranty from the manufacturer.
Testing requirements vary across all the equipment categories we sell. Temperature controlled units are tested with NIST traceable probes and data loggers. Gaskets, external housing, glass, handles, controls and control screens are all thoroughly inspected for integrity and functionality.
We test all equipment using the manufacturer's parameters and specifications to confirm that the unit operates properly.
We can ship products both nationally and internationally using a well-established network of transporters. Smaller items will ship via UPS. Larger equipment will be palletized and shipped either LTL or air-ride, depending on the specific equipment and/or delivery requirements.
American Instrument Exchange will accept the return of any product that is not working as represented and could not be replaced or repaired to the customer's satisfaction during the warranty period. Customers who cancel orders after refurbishing has begun will be subject to a cancellation and restocking fee of between 20% and 40%.
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