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PerkinElmer N5374099 Intracooler for DSC and Thermal Analysis
The PerkinElmer N5374099 Intracooler is a specialized subambient cooling system designed for compatible PerkinElmer differential scanning calorimeters and thermal analysis instruments. Manufactured for PerkinElmer by PolyScience, the Intracooler provides closed-loop mechanical refrigeration that extends the low-temperature capabilities of compatible DSC and thermal analysis systems without requiring liquid nitrogen for routine subambient operation.
Available used and refurbished from American Instrument Exchange, the PerkinElmer N5374099 is designed for use with compatible PerkinElmer Pyris and legacy thermal analysis instruments. Depending on the instrument and configuration, PerkinElmer Intracooler systems can extend DSC operation to temperatures as low as approximately -65°C. A 90-day warranty is included.
Key Features
Specialized subambient cooling system for thermal analysis
PerkinElmer model N5374099
Manufactured for PerkinElmer by PolyScience
Designed for compatible PerkinElmer DSC and thermal analyzers
Supports low-temperature DSC operation without routine liquid nitrogen cooling
Compatible with selected Pyris 1 DSC, Pyris 6 DSC, DSC 7, TMA 7, and DMA 7 systems
Closed-loop mechanical refrigeration
Automatic coolant circulation
Designed to connect directly to compatible analyzer cooling hardware
Compact floor or under-bench installation
230 V, 50/60 Hz configuration
Used, refurbished, and tested by American Instrument Exchange
90-day warranty included
Overview
The PerkinElmer N5374099 Intracooler differs substantially from a conventional laboratory recirculating chiller. Rather than serving as a general-purpose source of chilled fluid for multiple laboratory instruments, the Intracooler was engineered specifically to extend the subambient operating range of compatible PerkinElmer thermal analysis systems.
The system uses mechanical refrigeration and a dedicated circulating cooling arrangement to remove heat from the analyzer. When installed with the appropriate PerkinElmer hardware, the Intracooler allows thermal analysis experiments to begin substantially below room temperature.
This capability is particularly valuable in differential scanning calorimetry, where transitions such as glass transitions, crystallization events, melting behavior, and other thermal phenomena may occur below ambient temperature.
The N5374099 therefore should be evaluated primarily as a thermal-analysis accessory rather than as a conventional laboratory chiller.
Key Specifications
Specification
Details
Manufacturer
PerkinElmer
Manufactured By
PolyScience
Model / Part Number
N5374099
Equipment Type
Thermal analyzer Intracooler
Cooling Type
Mechanical refrigeration
Application
Subambient thermal analysis
Compatible Instrument Family
Selected PerkinElmer Pyris and legacy thermal analyzers
DSC Operating Capability
Down to approximately -65°C with compatible Intracooler configuration
Coolant Operation
Closed-loop circulation
Exterior Dimensions
Approx. 15 in. W × 20 in. D × 22.25 in. H
Electrical Requirements
230 V, 50/60 Hz, 7.5 A
Installation
Typically adjacent to or below compatible analyzer
Warranty
90 days
Common Applications
The PerkinElmer N5374099 Intracooler is primarily intended for subambient thermal analysis. Its most important application is extending the temperature range of compatible differential scanning calorimeters so researchers can investigate thermal transitions that occur below room temperature.
Typical DSC applications can include polymer characterization, glass-transition measurements, crystallization studies, melting-point and phase-transition analysis, pharmaceutical characterization, materials research, and evaluation of thermal properties across a broad temperature range.
Intracooler systems can also be used with certain compatible PerkinElmer thermomechanical and dynamic mechanical analysis instruments.
Because the N5374099 was engineered around specific PerkinElmer analyzer configurations, buyers should verify compatibility with their exact instrument and required mounting or connection hardware before purchase.
Ideal Laboratory Types
The PerkinElmer N5374099 is particularly relevant for materials-science laboratories, polymer research facilities, pharmaceutical laboratories, chemical R&D groups, quality-control departments, academic research laboratories, thermal analysis facilities, and industrial materials-testing environments.
It can be especially valuable for laboratories that routinely perform DSC experiments below room temperature but do not need the substantially lower temperatures or operating complexity associated with liquid-nitrogen cooling.
Laboratories already operating compatible legacy PerkinElmer thermal analyzers may also find a refurbished Intracooler useful for replacing an aging or failed cooling system while extending the service life of otherwise functional analytical equipment.
Temperature Control & Subambient Performance
The N5374099 is designed specifically to provide subambient cooling for compatible PerkinElmer thermal analyzers.
It is important to distinguish between the temperature capability of the Intracooler hardware and the resulting operating range of the complete analytical system. PerkinElmer's Intracooler configurations were designed to extend compatible DSC and thermal analysis instruments to specific subambient operating temperatures.
With the appropriate Intracooler configuration and compatible analyzer, DSC operation can extend to approximately -65°C.
Actual minimum achievable temperature depends on the thermal analyzer, Intracooler configuration, ambient laboratory conditions, electrical supply, cooling interface, and condition of the complete system.
For that reason, laboratories should evaluate the N5374099 according to the requirements of the complete PerkinElmer thermal analysis system rather than treating it as a standalone general-purpose -65°C chiller.
Circulation & Cooling Performance
The PerkinElmer Intracooler uses closed-loop mechanical refrigeration to continuously remove heat from the cooling interface connected to the thermal analyzer.
Unlike conventional laboratory recirculating chillers, where maximum pump flow and pressure are often primary selection criteria, the N5374099 was designed around the cooling requirements and interface of specific PerkinElmer analytical instruments.
The cooling system automatically circulates coolant through the appropriate chamber or cooling assembly to maintain the subambient conditions required by the analyzer.
This dedicated design is one reason instrument compatibility is more important than general pump specifications when selecting an Intracooler.
Buyers replacing an existing PerkinElmer cooling system should verify the analyzer model, existing connections, mounting hardware, and required accessories before purchase.
Refurbishment & Testing
This used PerkinElmer N5374099 Intracooler is refurbished and tested by American Instrument Exchange before shipment. Our technicians inspect the refrigeration system, circulation components, electrical system, condenser, controls, coolant connections, and other accessible components for proper operation.
The Intracooler is operated for extended periods to evaluate refrigeration performance, circulation, temperature pull-down, and overall system stability.
Because the N5374099 is designed to operate as part of a PerkinElmer thermal analysis system, standalone testing cannot duplicate every analytical application or instrument configuration. If your laboratory has a specific analyzer or target operating condition, please provide that information before shipment.
When practical, American Instrument Exchange will incorporate customer-requested operating conditions into final testing.
A 90-day warranty is included with this refurbished PerkinElmer Intracooler.
Choosing the Right Circulator or Thermal Analyzer Cooling System
The PerkinElmer N5374099 should be selected differently from a conventional recirculating chiller. The primary consideration is compatibility with the thermal analyzer rather than general cooling capacity, reservoir volume, or maximum pump flow.
PerkinElmer designed Intracoolers for specific DSC, TMA, and DMA systems. Laboratories should therefore confirm the exact analyzer model and required cooling interface before purchasing a replacement unit.
Temperature requirements are equally important. An Intracooler can provide convenient mechanical refrigeration for many routine subambient thermal-analysis experiments, avoiding the need for liquid nitrogen during procedures that remain within its operating capability.
Applications requiring substantially lower temperatures may require a different cooling configuration, while laboratories simply needing coolant for general analytical instruments should consider a conventional recirculating chiller instead.
American Instrument Exchange can help determine whether an available refurbished Intracooler or general-purpose laboratory chiller is the more appropriate solution based on your instrument and temperature requirements.
Related Equipment
American Instrument Exchange stocks a range of laboratory circulators, including dedicated analytical instrument cooling systems, recirculating chillers, refrigerated circulators, and heated circulating baths. Laboratories using the PerkinElmer N5374099 may also want to compare available thermal analysis instruments, laboratory water baths, and other refurbished analytical and laboratory equipment.
What is the PerkinElmer N5374099 Intracooler used for?
The N5374099 is a specialized refrigeration system used to provide subambient cooling for compatible PerkinElmer differential scanning calorimeters and other thermal analysis instruments.
Is the N5374099 a general-purpose laboratory chiller?
No. Although it uses refrigeration and circulating coolant, the N5374099 was designed specifically as an accessory for compatible PerkinElmer thermal analysis equipment.
Which PerkinElmer instruments can use an Intracooler?
PerkinElmer Intracoolers were designed for selected Pyris 1 DSC, Pyris 6 DSC, DSC 7, TMA 7, and DMA 7 systems. Exact compatibility and required hardware should be verified for the individual analyzer before purchase.
How cold can a PerkinElmer Intracooler operate?
The achievable analytical operating temperature depends on the specific Intracooler and analyzer configuration. Compatible PerkinElmer systems equipped with the appropriate Intracooler configuration can support DSC operation to approximately -65°C.
Can an Intracooler eliminate the need for liquid nitrogen?
For many routine subambient DSC applications within its temperature capability, an Intracooler can provide mechanical refrigeration without routine liquid-nitrogen cooling. Experiments requiring substantially lower temperatures may still require another cooling method.
Who manufactured the N5374099?
The N5374099 was supplied as a PerkinElmer thermal analysis accessory and manufactured for PerkinElmer by PolyScience.
What electrical service does this N5374099 require?
This American Instrument Exchange unit is configured for 230 V, 50/60 Hz electrical service and is rated at 7.5 A.
Does this refurbished PerkinElmer N5374099 include a warranty?
Yes. This used PerkinElmer N5374099 Intracooler is refurbished and tested by American Instrument Exchange and includes a 90-day warranty.
CLICK HEREto see the PerkinElmer Intracooler Chiller on our YouTube channel
Testing Procedures for Used and Refurbished Laboratory Equipment
Ensure Accuracy, Safety, and Dependable Performance Across Applications
At American Instrument Exchange, all used and refurbished laboratory equipment undergoes a rigorous, multi-point testing protocol to ensure optimal performance, operational safety, and long-term reliability. Whether the equipment is destined for research, diagnostics, quality control, or production environments, our thorough inspection and testing process is designed to meet the highest standards of laboratory excellence.
Why Testing Used Lab Equipment Is Essential
Before any refurbished laboratory equipment is returned to service, it must be carefully tested to verify:
• Functional integrity and operational performance
• Setpoint accuracy and repeatability (where applicable)
• User interface responsiveness and control features
Proper testing reduces the risk of equipment failure, measurement inaccuracies, or user hazards—helping to ensure consistent results in clinical, academic, biotech, and industrial labs.
Our standardized lab equipment testing procedures are tailored to each equipment type, ensuring every unit meets manufacturer specifications and industry benchmarks.
Key Testing Procedures for Refurbished and Used Laboratory Equipment
1. Initial Visual Inspection
• Examine equipment housing for signs of wear, corrosion, or damage
• Check ports, power cords, and exterior components for tampering or deterioration
• Verify that internal and external parts (racks, shelves, connectors, accessories) are present and undamaged
2. Functional Startup and Operational Testing
• Power on the equipment and verify startup diagnostics
• Confirm functionality of displays, buttons, switches, and control panels
• Run basic functions to confirm proper response and behavior under standard operating conditions
3. Testing and Performance Verification
• Test internal sensors or control systems using industry-standard tools
• Perform operational tests to validate accuracy and consistency
• Verify key performance specifications such as temperature control, timing, speed, or measurement outputs, depending on equipment type
4. Mechanical and Electrical System Testing
• Evaluate motors, pumps, fans, or other moving parts for smooth operation
• Inspect and test wiring, relays, fuses, and circuit boards for safety and reliability
• Test power delivery and grounding compliance
5. Safety and Compliance Checks
• Ensure equipment is grounded and insulated to meet laboratory safety standards
• Test alarms, interlocks, emergency stops, or safety shutdown systems if applicable
6. Final Quality Assurance and Documentation
• Perform extended runtime testing
• Document operational logs, testing results, and any repairs or adjustments made
• Complete a final inspection, thorough cleaning, and packaging for delivery
Trusted Quality from American Instrument Exchange
With over 50 years of experience in laboratory equipment refurbishment, American Instrument Exchange is committed to delivering certified, lab-ready instruments backed by expert testing. Our testing protocols ensure that each piece of equipment—regardless of type—is safe, accurate, and dependable from day one.
Whether you're equipping a startup lab or expanding a high-throughput facility, you can count on our refurbished laboratory equipment to perform with precision and reliability.
Refurbishment Protocol for Used Laboratory Equipment from American Instrument Exchange
At American Instrument Exchange, every piece of used laboratory equipment we offer undergoes a multi-step refurbishment process. Whether it's an analytical balance, centrifuge, freezer, oven, or any other essential lab instrument, our goal is to restore each unit to peak performance—ensuring accuracy, safety, and long-term reliability in scientific, clinical, industrial, and academic environments.
Why Choose Refurbished Lab Equipment from American Instrument Exchange?
• Thoroughly tested for performance, precision, and safety
• Backed by a warranty
• A cost-effective alternative to new equipment
• Environmentally sustainable through equipment reuse and waste reduction
• Serviced by expert technicians with decades of laboratory equipment experience
Step-by-Step Refurbishment Protocol
Every instrument and system refurbished at American Instrument Exchange follows a detailed, industry-aligned process:
1. Initial Intake & Inspection
• Complete visual and structural inspection for cosmetic damage, wear, or corrosion
• Mechanical assessment of hinges, seals, fasteners, motors, and moving parts
• Missing components and damaged items are documented for repair or replacement
2. Cleaning and Decontamination
• Full internal and external cleaning using non-abrasive, lab-safe solutions
• Removal of biological, chemical, or particulate contamination
• Disassembly and cleaning of removable parts such as trays, shelves, and filters
3. Mechanical and Electrical Repair
• Replacement or repair of worn or broken mechanical parts
• Evaluation and servicing of control panels, sensors, switches, and displays
• Testing and repair of electrical wiring, fuses, circuit boards, and power supplies
4. Functional System Testing
• Assessment of all major functions specific to the equipment type (e.g., speed, temperature, force, weight, timing)
• Operation of control interfaces, programming menus, and digital displays
• Verification of stabilization time, responsiveness, and user input reliability
5. Testing and Performance Verification
• Testing of internal sensors, controllers, and measurement systems using certified tools
• Multi-point testing to ensure repeatability, accuracy, and performance consistency
• Confirmation of user-defined setpoints, timing sequences, or programmable cycles
6. Safety and Compliance Checks
• Testing of safety interlocks, alarms, and over-limit protection systems (as applicable)
• Electrical safety inspections, including grounding and insulation verification
7. Final Quality Assurance and Documentation
• Full operational testing under simulated lab conditions
• Completion of performance benchmarks, testing results, and repair logs
• Final cleaning and visual inspection
Trust the Experts at American Instrument Exchange
With over 50 years of experience in the laboratory equipment industry, American Instrument Exchange is a trusted leader in high-quality refurbished lab instruments. Our refurbishment protocols ensure that every piece of equipment we sell is lab-ready—offering the precision, performance, and durability your team can count on.
Whether you’re outfitting a new lab or expanding an existing operation, choose American Instrument Exchange for tested, warrantied, and cost-effective laboratory equipment.
Warranty Information
All used equipment sold by American Instrument Exchange is refurbished/reconditioned, tested to meet specifications, cleaned, and comes with a 90-day warranty from the date of shipment unless otherwise specified. New products include a warranty from the manufacturer. Your warranty is only valid if you have paid your invoice. If your invoice is over 30 days old, warranty work will not be performed until your invoice is paid in full. American Instrument Exchange is not liable for any special or consequential damages that result from the use of, or the inability to use, the materials on this site or the performance of the products,
Exceptions include international sales and items that are agreed to be sold with a lesser warranty or items that are agreed to be sold “as is.”
Should there be visible shipping damage to packaging or concealed shipping damage to item(s) supplied, buyer must communicate such damage to the delivering entity or carrier upon receipt first and to American Instrument the same day item is accepted / signed for. Failure to do so voids warranty. Customer decision to involve / procure third party or OEM service other than American Instrument or AIE assigned vendors to resolve in-warranty instrument failure or defect without first placing a service call to American Instrument voids warranty.
Return & Cancellation Policy
American Instrument Exchange will authorize the return of and issue a full refund for any equipment that is not working as represented and could not be replaced or repaired to the customer’s satisfaction by AIE or a representative of AIE during the warranty period. Returns without prior authorization and an RMA number will not be accepted.
Customers are responsible for proper packaging of the equipment and all included accessories. American Instrument will pay for insurance and shipping costs. Non-inventory items bought specifically to fill customer orders may possibly be returned, but on a case by case basis.
Customers who cancel orders after refurbishing has begun or after delivery where there are no equipment performance issues may be subject to a Restocking/Cancellation Fee of 20% or more and responsible for shipping costs for both the delivery and return.
Ongoing and Extended Support Options
American Instrument Exchange is able to provide additional repair and support services outside the warranty terms for most products that sell.
For biosafety cabinets, clean benches, chemical fume hoods, and other clean air products our team at AIE Laboratory Services can provide certifications, repairs, decontaminations, and other services for customers throughout New England, and guidance and limited technical assistance for any customers in the US and Canada for new or refurbished biosafety cabinets purchased from American Instrument Exchange.
For all other products, the repair service team at American Instrument Exchange can provide both field and depot repair evaluations. We can easily schedule and coordinate the pick-up and transportation of your malfunctioning equipment. By offering hourly rates lower than most OEM service providers and eliminating travel time for technicians, we help reduce repair costs. Furthermore, our lab depot repair service minimizes or eliminates scheduling delays. Our experienced service technicians are qualified to restore your equipment to factory specifications.
Yes, all equipment from American Instrument Exchange comes with a warranty. Used/reconditioned/refurbished equipment is tested to make sure it operates to the manufacturer's specifications and comes with a 90-day warranty (unless otherwise noted). New equipment comes with a warranty from the manufacturer.
How do you test and recondition the equipment?
Testing requirements vary across all the equipment categories we sell. Temperature controlled units are tested with NIST traceable probes and data loggers. Gaskets, external housing, glass, handles, controls and control screens are all thoroughly inspected for integrity and functionality. We test all equipment using the manufacturer's parameters and specifications to confirm that the unit operates properly.
How do products ship from American Instrument Exchange?
We can ship products both nationally and internationally using a well-established network of transporters. Smaller items will ship via UPS. Larger equipment will be palletized and shipped either LTL or air-ride, depending on the specific equipment and/or delivery requirements.
Return and order cancellation policy
American Instrument Exchange will accept the return of any product that is not working as represented and could not be replaced or repaired to the customer's satisfaction during the warranty period. Customers who cancel orders after refurbishing has begun will be subject to a cancellation and restocking fee of between 20% and 40%.
Are discounts available for educational or non-profit institutions, or for bulk purchases?
Yes – call or email us today with a list of equipment you're looking for and we can potentially put together a quote that includes a discount.
How does your price matching policy work?
We strive to keep our pricing competitive and reasonable. If you find comparable items for sale at a lower price from other vendors please send us a link and or quote for the item and we'll do our best to match or beat the price.
Can I see the equipment in person before committing to a purchase?
Customers are welcome to make an appointment to view equipment in our warehouse. Given our workload we may not be able to test or clean the equipment prior to your arrival if you have not committed to an order.
1023 Western Avenue is a working warehouse, not a showroom, and customers should dress appropriately and wear closed toe shoes.
Can I ship products that I purchased elsewhere to American Instrument for repair?
Yes – please see our repair services page for more information.
