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LAB EQUIPMENT REPAIRS, INCLUDING ULTRALOW FREEZERS, FRIDGES, CENTRIFUGES AND MORE - Click here for details
LAB EQUIPMENT REPAIRS, INCLUDING ULTRALOW FREEZERS, FRIDGES, CENTRIFUGES AND MORE - Click here for details

Thermo Scientific 1397 Class II Type A2 Biosafety Cabinet

Fully Tested & Warrantied*
Product Code : SKU 0870XX BIO CAB

Shipping

All products ship from our 30,000 sq. ft. Haverhill, MA warehouse

Thermo Scientific 1397 Class II Type A2 Biosafety Cabinet

Refurbished Thermo Scientific 1397 Biosafety Cabinet for Sale

The Thermo Scientific 1397 is a premium 6-foot Class II Type A2 biosafety cabinet designed for laboratories requiring maximum workspace, dependable biological containment, and outstanding operating efficiency. As the largest model in Thermo Scientific's proven 1300 Series, the 1397 combines advanced airflow engineering, exceptional ergonomics, and industry-leading energy efficiency to support demanding laboratory workflows ranging from routine cell culture to pharmaceutical research and biotechnology applications.

Its expansive work area allows researchers to comfortably accommodate large culture vessels, multiple pipetting stations, laboratory instruments, and high-throughput sample processing without compromising aseptic technique. Thermo Scientific's proprietary airflow design creates an ISO Class 5 work environment while simultaneously protecting laboratory personnel and the surrounding environment through HEPA-filtered inflow and exhaust air.

The 1300 Series has earned an outstanding reputation for combining dependable biological containment with low operating costs. Its energy-efficient DC blower motor, quiet operation, ergonomic armrest, angled front sash, and thoughtfully designed workspace make the Thermo 1397 an excellent choice for laboratories where biosafety cabinets operate continuously throughout the workday.

At American Instrument Exchange, every Thermo Scientific 1397 biosafety cabinet is inspected and tested by our technicians before shipment. Unless otherwise specified, new HEPA filters are installed at our facility prior to delivery. Laboratories outfitting new research facilities or expanding existing operations can also browse our inventory of refurbished CO₂ incubators, centrifuges, laboratory refrigerators, ultra-low temperature freezers, autoclaves, and additional laboratory equipment to create a complete laboratory solution.


Key Features

  • Class II Type A2 biosafety cabinet

  • Approximately 6-foot nominal cabinet width

  • 8" sash opening in working position 
  • Large work area for high-throughput laboratory workflows

  • Proprietary Thermo Scientific airflow system

  • ISO Class 5 work environment

  • Energy-efficient DC blower motor

  • Low operating noise

  • HEPA-filtered supply and exhaust air

  • Ergonomic armrest and angled front opening

  • SmartCoat antimicrobial interior (model dependent)

  • Bright fluorescent or LED work lighting (configuration dependent)

  • Ideal for biotechnology, pharmaceutical, clinical, and academic laboratories


Overview

The Thermo Scientific 1397 was developed for laboratories requiring the largest available work area within the highly regarded 1300 Series biosafety cabinet family. Combining dependable Class II Type A2 containment with Thermo Scientific's energy-efficient airflow technology, the cabinet delivers outstanding performance for laboratories performing demanding biological research and high-volume laboratory workflows.

As a Class II Type A2 biosafety cabinet, the 1397 protects laboratory personnel through carefully controlled inward airflow while providing HEPA-filtered vertical laminar airflow across the work surface to protect sensitive biological materials. Exhaust air is HEPA filtered before returning to the laboratory, providing personnel, product, and environmental protection for a broad range of microbiology, molecular biology, biotechnology, pharmaceutical, and clinical laboratory applications.

The spacious 6-foot workspace is particularly valuable for laboratories processing large sample volumes, using multiple instruments inside the cabinet, or performing collaborative procedures requiring additional room for equipment and supplies. Researchers benefit from improved workflow organization while maintaining proper aseptic technique throughout complex laboratory procedures.

Combined with its quiet blower system, ergonomic operator position, reduced energy consumption, and dependable airflow performance, the Thermo Scientific 1397 remains one of the most popular large-format biosafety cabinets available for modern research laboratories.


Why Choose the Thermo Scientific 1397?

The Thermo Scientific 1397 is designed for laboratories where productivity depends on workspace. Its generous 6-foot work area allows researchers to comfortably perform complex procedures involving multiple culture vessels, pipettes, reagent containers, and laboratory instruments without overcrowding the cabinet interior.

Unlike many large biosafety cabinets that require substantially greater operating power, the Thermo 1397 combines high-capacity performance with remarkably low energy consumption through its efficient DC blower technology. This allows laboratories to reduce long-term operating costs while maintaining stable airflow and dependable biological containment.

The cabinet also emphasizes operator comfort through ergonomic armrests, a comfortable viewing angle, low operating noise, and thoughtful workspace design that reduces fatigue during extended laboratory procedures. These features make the 1397 particularly attractive for laboratories where biosafety cabinets are used continuously throughout the day.

For organizations seeking a dependable, large-format biosafety cabinet with proven performance, exceptional ergonomics, and economical operation, the Thermo Scientific 1397 continues to be an outstanding choice.


Thermo Scientific 1397 vs. Smaller 1300 Series Models

The Thermo Scientific 1397 shares the same proven airflow technology, biological containment performance, and energy-efficient design found throughout the 1300 Series while providing substantially more usable workspace for larger research projects and higher-throughput laboratory operations.

Compared with 4-foot and 5-foot models, the 1397 offers additional room for larger culture vessels, multiple sample racks, laboratory instrumentation, and collaborative workflows involving more than one operator. Laboratories performing pharmaceutical research, biotechnology applications, vaccine development, and large-scale cell culture frequently choose the 1397 when maximum work area is a priority.

For facilities that value dependable containment, low operating costs, and increased productivity, the Thermo Scientific 1397 provides the largest standard workspace available within the proven 1300 Series platform.


Compatible Laboratory Equipment

The Thermo Scientific 1397 is commonly integrated into complete laboratory workflows supporting biotechnology research, pharmaceutical development, vaccine production, microbiology, and advanced cell culture applications. Its large work area makes it an excellent centerpiece for laboratories utilizing multiple instruments and high-throughput workflows.

Frequently paired equipment includes CO₂ incubators for mammalian cell culture, refrigerated and floor-model centrifuges for sample preparation, ultra-low temperature freezers for long-term specimen storage, laboratory refrigerators for media and reagent storage, compound and inverted microscopes for cell analysis, autoclaves for sterilization, and cryogenic storage systems for biological sample preservation.

American Instrument Exchange maintains an extensive inventory of professionally refurbished laboratory equipment, allowing customers to source compatible instruments from a single supplier while simplifying procurement and reducing lead times.


Common Applications

The Thermo Scientific 1397 is designed for demanding laboratory environments requiring dependable biological containment together with a spacious work area capable of supporting complex research and production workflows.

  • Mammalian cell culture

  • Stem cell research

  • Molecular biology

  • Microbiology

  • Virology

  • Gene and cell therapy research

  • Pharmaceutical research

  • Vaccine development

  • Clinical diagnostics

  • Biotechnology research

  • Academic research laboratories

  • Government research facilities


Ideal Laboratory Environments

The Thermo Scientific 1397 is frequently installed in biotechnology companies, pharmaceutical manufacturers, university core laboratories, hospital research centers, contract research organizations, and clinical laboratories where maximum workspace, dependable biological containment, and low operating costs are essential. Its combination of proven airflow engineering, ergonomic operator design, and energy-efficient performance makes it an excellent choice for laboratories operating biosafety cabinets throughout the workday.


Key Specifications

Specification Details
Manufacturer Thermo Scientific
Model 1397
Cabinet Type Class II Type A2 Biosafety Cabinet
Nominal Width 6 ft
Exterior Dimensions 74.8" W × 31.5" D × 61.8" H
Interior Width Approximately 74.8"
Airflow Vertical Laminar Flow
Supply Filtration H14 HEPA (99.995% MPPS)
Exhaust Filtration H14 HEPA (99.995% MPPS)
Blower Motor Energy-efficient DC motor
Interior Finish SmartCoat antimicrobial or stainless steel (configuration dependent)
Noise Level Approximately 64 dBA
Electrical 120V, 50/60 Hz
Certifications NSF/ANSI 49, UL, CE

Specifications compiled from Thermo Scientific manufacturer literature and American Instrument Exchange product information.

Why Buy a Refurbished Thermo Scientific Biosafety Cabinet?

Thermo Scientific biosafety cabinets have become a benchmark for laboratories seeking dependable biological containment combined with ergonomic design and energy-efficient operation. The Thermo Scientific 1397 builds upon the proven 1300 Series platform, delivering exceptional airflow performance, low operating costs, and one of the largest work areas available in a Class II Type A2 biosafety cabinet.

Purchasing a professionally refurbished Thermo Scientific 1397 allows laboratories to obtain premium laboratory equipment while significantly reducing capital expenditures compared to purchasing new. The cabinet's energy-efficient DC blower motor, quiet operation, ergonomic operator design, and proven airflow technology make it an outstanding long-term investment for laboratories that depend on their biosafety cabinets every day.

For biotechnology companies, pharmaceutical manufacturers, research institutions, hospitals, and clinical laboratories, a refurbished Thermo Scientific 1397 offers dependable performance, excellent operator comfort, and outstanding value without compromising laboratory safety or biological containment.


Refurbishment & Testing Process

Every Thermo Scientific 1397 biosafety cabinet received by American Instrument Exchange undergoes a comprehensive inspection, cleaning, and refurbishment process before being offered for sale. Our technicians evaluate the cabinet's mechanical, electrical, and airflow systems to verify proper operation and identify components requiring service or replacement.

Unless otherwise specified, new HEPA filters are installed at our facility before shipment. The blower assembly, electrical controls, alarms, lighting, sash operation, and cabinet electronics are thoroughly inspected and tested to verify reliable operation. Interior stainless steel surfaces are professionally cleaned, and worn cosmetic or functional components are repaired or replaced whenever practical.

Each refurbished Thermo Scientific 1397 is prepared for installation and field certification, allowing laboratories to place the cabinet into service with confidence following certification.


Certification Readiness

Proper certification is required whenever a biosafety cabinet is installed, relocated, or returned to service. Following refurbishment, the Thermo Scientific 1397 is prepared for field certification to verify inflow and downflow velocities, HEPA filter integrity, cabinet pressurization, alarm operation, and overall compliance with current NSF/ANSI 49 performance requirements.

For laboratories throughout New England, AIE Laboratory Services provides on-site biosafety cabinet certification, preventative maintenance, HEPA filter replacement, repairs, equipment relocation, and annual recertification. Our experienced field service technicians help laboratories maintain regulatory compliance while maximizing equipment reliability and operational uptime.


Shipping & Installation

The Thermo Scientific 1397 is professionally packaged using commercial laboratory equipment packaging designed to protect the cabinet during transportation. Because biosafety cabinets are precision airflow devices, proper handling during shipping, unloading, and installation is essential to preserving airflow performance and cabinet integrity.

American Instrument Exchange can assist customers with freight coordination, inside delivery, laboratory placement, and installation planning. Regional installation assistance is also available. Following installation, the cabinet should be certified before biological research, pharmaceutical production, or clinical laboratory procedures begin.


Related Laboratory Equipment

The Thermo Scientific 1397 is frequently installed as part of complete laboratory workflows supporting biotechnology research, pharmaceutical development, microbiology, vaccine research, and cell culture applications. American Instrument Exchange offers a broad inventory of professionally refurbished laboratory equipment that complements the 1397 and helps laboratories source compatible equipment from a single supplier.

Frequently paired equipment includes:

  • CO₂ incubators for mammalian cell culture and microbial incubation

  • Refrigerated and floor-model centrifuges for sample preparation and harvesting

  • Laboratory refrigerators and ultra-low temperature freezers for reagent and specimen storage

  • Inverted and compound microscopes for routine cell analysis

  • Laboratory autoclaves for sterilization of media, instruments, and laboratory waste

  • Laboratory water baths for warming media and reagents

  • Cryogenic storage systems for long-term biological sample preservation

Purchasing compatible laboratory equipment from American Instrument Exchange can simplify procurement, reduce lead times, and create a consistent refurbishment standard throughout the laboratory.


Thermo Scientific 1397 Frequently Asked Questions

What type of biosafety cabinet is the Thermo Scientific 1397?

The Thermo Scientific 1397 is a Class II Type A2 biosafety cabinet that provides personnel, product, and environmental protection through HEPA-filtered airflow. It is designed for contamination-sensitive biological research, pharmaceutical applications, microbiology, and clinical laboratory work.


What are the advantages of a 6-foot biosafety cabinet?

The 6-foot work area provides significantly more usable workspace than smaller cabinets, making it ideal for laboratories working with large culture vessels, multiple pipetting stations, laboratory instruments, or higher sample volumes. The additional space also improves workflow organization while maintaining proper aseptic technique.


Is the Thermo Scientific 1397 energy efficient?

Yes. The 1397 utilizes an energy-efficient DC blower motor that consumes substantially less electricity than many older AC blower systems while maintaining stable airflow performance. This contributes to lower operating costs and quieter cabinet operation.


Does the cabinet include new HEPA filters?

Unless otherwise specified, American Instrument Exchange installs new HEPA filters as part of the refurbishment process before shipment.


Is the Thermo Scientific 1397 suitable for cell culture?

Yes. The Thermo Scientific 1397 is widely used for mammalian cell culture, stem cell research, molecular biology, microbiology, pharmaceutical research, vaccine development, biotechnology applications, and other procedures requiring an ISO Class 5 work environment.


Does the cabinet require certification?

Yes. Like all biosafety cabinets, the Thermo Scientific 1397 should be certified after installation or relocation and recertified at regular intervals to verify airflow performance, HEPA filter integrity, and continued compliance with NSF/ANSI 49 standards.


Can American Instrument Exchange provide certification services?

Yes. Through AIE Laboratory Services, we provide biosafety cabinet certification, preventative maintenance, HEPA filter replacement, repairs, equipment relocation, and ongoing field service throughout New England.


Why purchase a refurbished Thermo Scientific 1397 from American Instrument Exchange?

Every Thermo Scientific 1397 biosafety cabinet undergoes inspection, testing, cleaning, and refurbishment by experienced technicians before shipment. Combined with new HEPA filters (unless otherwise specified), responsive customer support, optional field certification, and ongoing service through AIE Laboratory Services, a refurbished Thermo Scientific 1397 provides laboratories with dependable biological containment at a substantially lower cost than purchasing new equipment.

Testing Procedures for Used and Refurbished Biosafety Cabinets

Ensure Containment, Airflow Integrity, and Operator Safety

Used and refurbished biosafety cabinets (BSCs) from American Instrument Exchange are thoroughly tested to ensure they meet NSF/ANSI 49 performance standards for containment, airflow uniformity, and HEPA filtration. Each Class I, II, or III unit is evaluated through a series of specialized inspections and certifications, ensuring the cabinet performs reliably in research, clinical, and pharmaceutical lab environments.

Why Testing Used Biosafety Cabinets Is Essential

Before any biosafety cabinet is deployed in a working lab, it must be tested for:

• HEPA filter integrity and leak-free performance
• Inflow and downflow air velocity balance
• Containment efficiency and personnel protection
• Electrical system function and safety compliance
• Cleanliness and readiness for sterile applications

Proper testing of refurbished biosafety cabinets helps prevent cross-contamination, exposure to hazardous materials, and airflow disruption—critical for maintaining laboratory protocols. Our structured multi-point BSC testing protocol ensures dependable protection for operators, products, and the lab environment.

Key Testing Procedures for Refurbished and Used Biosafety Cabinets

1. Initial Visual Inspection

• Inspect exterior panels, window sashes, hinges, and seals for signs of wear or damage
• Confirm visibility and integrity of the viewing window
• Check power cords, display screens, and control interfaces for usability

2. Cabinet Decontamination and Cleaning

• Interior and exterior cleaned with non-corrosive disinfectants
• Decontamination protocols followed to remove biological contaminants
• Work surface, sidewalls, and return air grills are fully sanitized

3. HEPA Filter Integrity Testing (DOP/PAO Leak Test)

• Conduct aerosol challenge test using PAO or DOP to verify HEPA filter seal integrity
• Identify and resolve any filter leaks in accordance with NSF/ANSI 49 standards
• Ensure HEPA filters are correctly seated and uncompromised

4. Inflow and Downflow Velocity Testing

• Measure air velocities using calibrated thermo-anemometers
• Confirm inflow velocity meets requirements
• Verify downflow uniformity within the work zone to prevent turbulence and contamination

5. Airflow Smoke Pattern Testing

• Conduct visual smoke tests to demonstrate laminar airflow and containment
• Confirm that airflow barriers prevent cross-contamination and exposure

6. Electrical Safety and Alarm System Checks

• Inspect grounding, insulation resistance, and GFCI protection
• Test alarm functionality for sash position, airflow disruption, and power failure
• Verify interior lighting, outlets, and blower controls operate reliably

7. Final Certification and Quality Assurance

• Run full performance test cycle and confirm compliance with NSF/ANSI 49 and manufacturer specs
• Document data and generate a detailed service report

Guaranteed Performance from American Instrument Exchange

All refurbished biosafety cabinets from American Instrument Exchange are tested and verified to ensure maximum containment, user protection, and airflow performance. Whether used for microbiology, tissue culture, pharmaceutical compounding, or other work necessitating containment, our BSCs meet industry standards—so your team can work safely and confidently from day one.

Repair and Refurbishment Protocol for Used Biosafety Cabinets

Certified Protection and Performance from American Instrument Exchange

At American Instrument Exchange, every used biosafety cabinet (BSC) we offer is thoroughly repaired and refurbished to meet the highest standards for safety, airflow performance, and compliance. Whether it’s a Class I, Class II Type A2/B2, or Class III unit, we follow a meticulous refurbishment process to ensure your BSC provides reliable containment, sterile workspace conditions, and long-term durability.

Why Choose a Refurbished Biosafety Cabinet from American Instrument Exchange?

  • Fully tested and certified for airflow integrity and containment
  • Backed by warranty and performance guarantee
  • Cost-effective alternative to new biosafety cabinets
  • Environmentally responsible through expert reuse and restoration
  • Serviced by experienced technicians trained in NSF/ANSI 49 protocols

Step-by-Step Refurbishment Protocol

Every biosafety cabinet at American Instrument Exchange undergoes the following comprehensive multi-stage process to ensure it is lab-ready:

1. Initial Intake & Inspection

• Visual inspection of cabinet exterior, control panel, and sash mechanism
• Evaluation of hinges, seals, gaskets, and electrical components
• Missing parts or functional issues are documented for repair

2. Cleaning and Decontamination

• Full internal and external cleaning using non-abrasive, disinfectant-safe products
• Decontamination protocols followed to remove biohazardous or chemical residue
• Removable surfaces, work trays, and grilles are cleaned and sanitized

3. Mechanical and Electrical Repair

• Repair or replacement of worn components, including sash latches, lighting, and controls
• Electrical systems including switches, alarms, and outlets are tested and serviced
• Wiring is inspected and repaired to meet safety and performance standards

4. HEPA Filter Evaluation and Replacement

• Filters are tested for integrity using DOP/PAO aerosol challenge testing
• HEPA filters are replaced with OEM or equivalent filters
• Filter seals are verified for leak-free performance

5. Airflow and Performance Testing

• Inflow and downflow velocities are measured using calibrated instruments
• Smoke pattern testing confirms laminar airflow and containment effectiveness
• Blower motor function and airflow uniformity are verified across the cabinet

6. Safety System Verification

• Alarms for airflow disruption, sash height, and power loss are tested
• GFCI protection, lighting, and emergency shutoff systems are confirmed functional

7. Final Quality Control and Certification

• Performance testing is conducted to confirm NSF/ANSI 49 compliance (where applicable)
• Final visual inspection and cleaning performed prior to shipping
• Detailed service report and airflow test results provided with each unit

Trust the Experts at American Instrument Exchange

With over 50 years of experience in the lab equipment industry, American Instrument Exchange is a trusted name in refurbished biosafety cabinets. Our repair and refurbishment protocol ensures each cabinet provides dependable protection for personnel, products, and the environment—delivering maximum safety at a fraction of the cost of new.

Warranty Information

All used equipment sold by American Instrument Exchange is refurbished/reconditioned, tested to meet specifications, cleaned, and comes with a 90-day warranty from the date of shipment unless otherwise specified. New products include a warranty from the manufacturer. Your warranty is only valid if you have paid your invoice. If your invoice is over 30 days old, warranty work will not be performed until your invoice is paid in full.  American Instrument Exchange is not liable for any special or consequential damages that result from the use of, or the inability to use, the materials on this site or the performance of the products,

Exceptions include international sales and items that are agreed to be sold with a lesser warranty or items that are agreed to be sold “as is.”

Should there be visible shipping damage to packaging or concealed shipping damage to item(s) supplied, buyer must communicate such damage to the delivering entity or carrier upon receipt first and to American Instrument the same day item is accepted / signed for. Failure to do so voids warranty. Customer decision to involve / procure third party or OEM service other than American Instrument or AIE assigned vendors to resolve in-warranty instrument failure or defect without first placing a service call to American Instrument voids warranty.

Return & Cancellation Policy

American Instrument Exchange will authorize the return of and issue a full refund for any equipment that is not working as represented and could not be replaced or repaired to the customer’s satisfaction by AIE or a representative of AIE during the warranty period. Returns without prior authorization and an RMA number will not be accepted. 

Customers are responsible for proper packaging of the equipment and all included accessories. American Instrument will pay for insurance and shipping costs. Non-inventory items bought specifically to fill customer orders may possibly be returned, but on a case by case basis.

Customers who cancel orders after refurbishing has begun or after delivery where there are no equipment performance issues may be subject to a Restocking/Cancellation Fee of 20% or more and responsible for shipping costs for both the delivery and return.

Ongoing and Extended Support Options

American Instrument Exchange is able to provide additional repair and support services outside the warranty terms for most products that sell.

For biosafety cabinets, clean benches, chemical fume hoods, and other clean air products our team at AIE Laboratory Services can provide certifications, repairs, decontaminations, and other services for customers throughout New England, and guidance and limited technical assistance for any customers in the US and Canada for new or refurbished biosafety cabinets purchased from American Instrument Exchange.

For all other products, the repair service team at American Instrument Exchange can provide both field and depot repair evaluations. We can easily schedule and coordinate the pick-up and transportation of your malfunctioning equipment. By offering hourly rates lower than most OEM service providers and eliminating travel time for technicians, we help reduce repair costs. Furthermore, our lab depot repair service minimizes or eliminates scheduling delays. Our experienced service technicians are qualified to restore your equipment to factory specifications.

Please contact our team at info@americaninstrument.com for more details.

FAQ

Does the equipment come with a warranty?

Yes, all equipment from American Instrument Exchange comes with a warranty.
Used/reconditioned/refurbished equipment is tested to make sure it operates to the manufacturer's specifications and comes with a 90-day warranty (unless otherwise noted). New equipment comes with a warranty from the manufacturer.

How do you test and recondition the equipment?

Testing requirements vary across all the equipment categories we sell. Temperature controlled units are tested with NIST traceable probes and data loggers. Gaskets, external housing, glass, handles, controls and control screens are all thoroughly inspected for integrity and functionality.
We test all equipment using the manufacturer's parameters and specifications to confirm that the unit operates properly.

How do products ship from American Instrument Exchange?

We can ship products both nationally and internationally using a well-established network of transporters. Smaller items will ship via UPS. Larger equipment will be palletized and shipped either LTL or air-ride, depending on the specific equipment and/or delivery requirements.

Return and order cancellation policy

American Instrument Exchange will accept the return of any product that is not working as represented and could not be replaced or repaired to the customer's satisfaction during the warranty period. Customers who cancel orders after refurbishing has begun will be subject to a cancellation and restocking fee of between 20% and 40%.

Are discounts available for educational or non-profit institutions, or for bulk purchases?

Yes – call or email us today with a list of equipment you're looking for and we can potentially put together a quote that includes a discount.

How does your price matching policy work?

We strive to keep our pricing competitive and reasonable. If you find comparable items for sale at a lower price from other vendors please send us a link and or quote for the item and we'll do our best to match or beat the price.

Can I see the equipment in person before committing to a purchase?

Customers are welcome to make an appointment to view equipment in our warehouse. Given our workload we may not be able to test or clean the equipment prior to your arrival if you have not committed to an order.

1023 Western Avenue is a working warehouse, not a showroom, and customers should dress appropriately and wear closed toe shoes.

Can I ship products that I purchased elsewhere to American Instrument for repair?

Yes – please see our repair services page for more information.