Thermo Scientific Heratherm IMH750-S Large-Capacity Security Incubator

Thermo Scientific Heratherm IMH750-S Large-Capacity Security Incubator

The Thermo Scientific Heratherm IMH750-S Advanced Protocol Security Incubator is a large-capacity mechanical-convection microbiological incubator designed for pharmaceutical research, microbiology, clinical laboratories, quality control, regulated testing, sample incubation, and other applications where dependable temperature control and enhanced sample protection are important. With approximately 702 L (24.8 cu. ft.) of usable chamber capacity, mechanical convection, an ambient +5°C to 105°C operating range, automatic temperature alarms, programmable timer functions, and a certified 140°C decontamination cycle, the IMH750-S combines large-scale incubation capacity with advanced contamination-control and monitoring features.

Available used and refurbished from American Instrument Exchange, the Heratherm IMH750-S is particularly well suited for laboratories that need substantially more capacity than a conventional benchtop incubator while maintaining precise temperature control and a cleanable stainless steel chamber. Its broad temperature range also allows the unit to support applications extending beyond routine 37°C incubation, including elevated-temperature testing and selected drying procedures.

Key Features

• Large 702 L (24.8 cu. ft.) usable chamber capacity

• Advanced Protocol Security incubator configuration

• Mechanical convection for temperature uniformity

• Temperature range from ambient +5°C to 105°C

• Approximately ±0.3°C spatial temperature deviation at 37°C

• Approximately ±0.2°C temperature stability at 37°C

• Certified 140°C high-temperature decontamination cycle

• Six-hour decontamination cycle under specified conditions

• Automatic high- and low-temperature alarms

• Door-open monitoring and alarm functions

• Advanced digital timer

• Daily, weekly, and real-time timer programming

• Stainless steel AISI 304 interior

• Large vacuum fluorescent control display

• Internal glass door for sample observation

• Access port for independent monitoring probes or compatible equipment

• Two shelves supplied

• Capacity for up to 39 shelf positions

• Floor-standing large-capacity design

• Casters for positioning and installation

• 120V, 60 Hz configuration

• Professionally inspected and tested by American Instrument Exchange

• 90-day warranty included

Thermo Scientific Heratherm IMH750-S Overview

The Heratherm IMH750-S is part of Thermo Scientific's Advanced Protocol Security incubator family, a series developed for laboratories that require more sample protection and contamination-control capability than a basic general-purpose incubator provides.

The IMH750-S is the largest model in this family, providing approximately 702 L, or 24.8 cu. ft., of usable interior capacity. Although the model designation includes “750,” the published usable chamber volume is approximately 702 L.

This large reach-in configuration allows laboratories to consolidate substantial sample loads into a single controlled chamber rather than distributing work among numerous smaller incubators.

Unlike the Heratherm IGS750 General Protocol model, which uses gravity convection and operates to 75°C, the IMH750-S incorporates mechanical convection and operates to 105°C. Forced air circulation helps distribute heated air throughout the large chamber, supporting improved temperature uniformity when shelves are populated with samples.

The chamber interior is manufactured from AISI 304 stainless steel, providing a durable, corrosion-resistant surface that is well suited to repeated laboratory use and routine cleaning.

An internal glass door allows researchers to inspect cultures and samples without immediately exposing the entire chamber to room air, helping reduce unnecessary temperature disruption.

Common Applications

The Thermo Heratherm IMH750-S is well suited for microbiology, pharmaceutical research, clinical laboratory procedures, quality control, food and beverage testing, environmental microbiology, biotechnology, sample incubation, media conditioning, stability-related testing, and other temperature-controlled laboratory applications.

The approximately 24.8 cu. ft. chamber provides substantial capacity for laboratories processing large numbers of plates, bottles, containers, or other samples simultaneously.

At conventional incubation temperatures around 30°C to 37°C, the IMH750-S can support microbial cultures and many routine microbiological procedures. Its substantially higher maximum temperature of 105°C broadens its application range beyond biological incubation.

Selected laboratories may use the higher-temperature capability for sample conditioning, thermal testing, warming, or drying procedures when appropriate for the materials and protocol involved.

The large chamber can also accommodate compatible laboratory equipment. A built-in access port allows cables or independent monitoring probes to enter the chamber without requiring the main door to remain partially open.

Laboratories using the IMH750-S for microbiological workflows may pair it with biosafety cabinets for aseptic or containment-sensitive sample handling and laboratory centrifuges for sample preparation. Laboratory refrigerators and laboratory freezers can provide complementary temperature-controlled storage.

Sample Types & Incubation Applications

The broad temperature range and large interior make the Heratherm IMH750-S useful for a wide variety of microbiological, pharmaceutical, industrial, and quality-control workflows.

Common Samples & Applications

• Bacterial cultures

• Yeast and fungal cultures

• Microbiological test plates

• Culture media

• Pharmaceutical QC samples

• Environmental monitoring samples

• Food and beverage microbiology samples

• Clinical laboratory samples

• Stability and conditioning samples

• Industrial quality-control specimens

Typical Laboratory Containers

• Petri dishes

• Culture plates

• Bottles

• Flasks

• Test tubes

• Sample containers

• Media bottles

• Microbiological test vessels

Two shelves are supplied with the standard IMH750-S platform, while the chamber incorporates a highly flexible shelf-support system capable of accommodating substantially more shelves when applications require high-density storage of shorter sample containers.

Users should avoid excessively dense loading that could obstruct airflow. Because the IMH750-S relies on mechanical convection, maintaining adequate space around sample containers helps heated air circulate throughout the chamber and supports consistent temperature performance.

Temperature Control & Environmental Stability

Maintaining temperature uniformity across a chamber exceeding 700 L is considerably more challenging than controlling a small benchtop incubator.

The IMH750-S addresses this through mechanical convection, continuously circulating chamber air to reduce temperature gradients between different shelf positions.

Thermo specifies an operating temperature range from approximately 5°C above ambient to 105°C.

At 37°C, published specifications indicate spatial temperature deviation of approximately ±0.3°C and temperature stability over time of approximately ±0.2°C under defined operating conditions.

These specifications make the IMH750-S appropriate for applications in which large sample loads must be maintained under consistent thermal conditions.

The Advanced Protocol Security control system also incorporates automatic over- and under-temperature alarms. If chamber temperature moves outside established operating limits, the alarm system alerts laboratory personnel to the deviation.

Door status is monitored as well, helping identify a door that has been left open or has not been closed correctly.

For laboratories performing extended incubations, these monitoring capabilities can provide meaningful additional protection for valuable samples.

140°C High-Temperature Decontamination

One of the defining features of the Heratherm Advanced Protocol Security platform is its 140°C high-temperature decontamination cycle.

Instead of relying solely on chemical disinfectants or requiring all interior components to be removed and autoclaved separately, the incubator can heat the chamber and internal fittings to a substantially elevated temperature as part of a dedicated decontamination routine.

Thermo developed the cycle to operate at 140°C for a six-hour heating process under specified conditions. The decontamination routine was independently evaluated by an accredited microbiological institute.

For laboratories performing microbiological work, this capability provides a significant advantage over a conventional general-purpose incubator.

Warm incubation chambers can become contaminated by bacteria, molds, fungi, or other microorganisms introduced through samples, containers, spills, or routine door openings. Periodic high-temperature decontamination provides another tool for reducing contamination within the chamber.

The cycle does not eliminate the need for routine cleaning. Visible spills, culture residues, and other material should still be removed according to appropriate laboratory procedures before decontamination.

The combination of stainless steel construction, accessible interior surfaces, and the 140°C cycle makes the IMH750-S particularly attractive for laboratories where contamination control is a high priority.

Advanced Timer & Monitoring Features

The Heratherm IMH750-S incorporates an advanced digital timer that provides considerably more automation than a simple countdown timer.

Users can configure basic timed operation, recurring weekly schedules, or incubation activity based on a 24-hour clock.

This can be useful for laboratories running standardized workflows where heating should begin before staff arrive, incubation should run for a defined duration, or operating schedules repeat from week to week.

Temperature and operating information are presented through a large vacuum fluorescent display, designed for clear visibility during routine laboratory operation.

The unit also includes an access port that can be used with an independent temperature sensor or monitoring device. This is useful when laboratories need a secondary measurement system for qualification, validation, data logging, or process monitoring.

The same access port can support compatible equipment such as stirrers or other devices operated inside the chamber, provided their dimensions, electrical requirements, heat output, and temperature limitations are appropriate for the application.

Thermo Scientific Heratherm IMH750-S Specifications

The IMH750-S designation corresponds to the large-capacity Advanced Protocol Security model; published usable chamber volume is approximately 702 L despite the “750” model designation. Specifications should be confirmed for the individual refurbished unit before purchase. Physical door-lock configuration should also be confirmed because Thermo literature varies regarding the lock feature on large-capacity Advanced Protocol Security models.

Thermo Scientific Heratherm IMH750-S Frequently Asked Questions

What does “Security” mean on the Heratherm IMH750-S?

The Advanced Protocol Security designation refers primarily to additional sample-protection and contamination-control features. These include automatic over- and under-temperature alarms, door monitoring, programmable operation, and the 140°C high-temperature decontamination cycle.

Is the Heratherm IMH750-S a CO₂ incubator?

No. The IMH750-S is a microbiological temperature incubator, not a CO₂ incubator. It controls temperature but does not provide regulated CO₂, humidity, or oxygen control. Laboratories requiring a controlled CO₂ atmosphere should select a dedicated CO₂ incubator.

What is the capacity of the Heratherm IMH750-S?

The IMH750-S provides approximately 702 L, or 24.8 cu. ft., of usable chamber volume. Although its model name includes “750,” Thermo's published specifications list the actual usable capacity as 702 L.

What is the difference between the Heratherm IMH750-S and IGS750?

The IGS750 is a General Protocol gravity-convection incubator, while the IMH750-S is an Advanced Protocol Security mechanical-convection model. The IMH750-S also offers a higher maximum temperature of 105°C, enhanced alarm and timer capabilities, and the 140°C decontamination cycle.

Does the IMH750-S have a high-temperature decontamination cycle?

Yes. The IMH750-S incorporates Thermo's 140°C decontamination routine, designed to reduce microorganisms within the chamber and on internal fittings during a dedicated high-temperature cycle.

Can the IMH750-S be used at 37°C for microbiology?

Yes. The incubator is well suited for routine microbiological incubation at 37°C as well as other temperatures within its ambient +5°C to 105°C operating range. Mechanical convection helps maintain uniform chamber conditions across large sample loads.

Can equipment be operated inside the Heratherm IMH750-S?

The incubator incorporates an access port for independent sensors and compatible laboratory equipment. Depending on the application, equipment such as a stirrer may be operated inside the chamber. Users should verify the equipment's temperature rating, dimensions, heat generation, power requirements, and effect on chamber airflow before use.

Is the door on the IMH750-S lockable?

Thermo documentation is inconsistent on this particular point. Advanced Protocol Security incubators are generally associated with restricted-access door features, but some Thermo literature specifically excludes the large-capacity models from the lockable-door specification. The physical door configuration should therefore be confirmed on the individual IMH750-S before purchase.

Is this Thermo Heratherm IMH750-S refurbished?

Used Thermo Scientific Heratherm IMH750-S incubators offered by American Instrument Exchange are inspected, cleaned, and tested prior to shipment. Temperature performance, mechanical convection, controls, alarms, timer functions, door monitoring, and other installed features are evaluated as applicable. The 140°C decontamination function is also tested as part of the refurbishment process when operational testing conditions permit, with components replaced as necessary. Refurbished equipment includes a 90-day warranty.