Thermo Scientific Multifuge X4R Pro-MD Refrigerated Centrifuge

Product Code : SKU 1397I CENTRI

Price Match Policy

Shipping

All products ship from our 30,000 sq. ft. Haverhill, MA warehouse

Thermo Scientific Multifuge X4R Pro-MD Refrigerated Centrifuge with TX-1000 Rotor and Buckets – Refurbished

The Thermo Scientific Multifuge X4R Pro-MD Refrigerated Centrifuge is a high-capacity, multipurpose benchtop centrifuge designed for clinical laboratories, biotechnology research, pharmaceutical development, cell culture, and general laboratory sample preparation. Combining advanced refrigeration, touchscreen controls, flexible rotor compatibility, and high-throughput processing capabilities, the X4R Pro-MD provides reliable performance for laboratories requiring efficient separation of biological samples.

This refurbished Thermo Scientific X4R Pro-MD from American Instrument Exchange includes a TX-1000 swinging-bucket rotor with four 1,000 mL buckets, providing a maximum total sample capacity of 4 liters. The included rotor operates at speeds up to 4,200 RPM and generates centrifugal forces up to 4,122 × g in the refrigerated X4R Pro-MD.

The centrifuge also supports a wide selection of compatible fixed-angle and swinging-bucket rotors, allowing laboratories to process blood collection tubes, conical tubes, centrifuge bottles, microplates, and other sample formats with appropriate accessories.

Its refrigerated temperature range of -10°C to +40°C helps maintain controlled conditions for temperature-sensitive biological materials, while the intuitive touchscreen interface simplifies programming and routine operation.

American Instrument Exchange professionally inspects, refurbishes, and tests used laboratory centrifuges before shipment. This refurbished Thermo Scientific X4R Pro-MD includes a 90-day warranty.

Key Features

Thermo Scientific Multifuge X4R Pro-MD refrigerated benchtop centrifuge
Includes TX-1000 swinging-bucket rotor and four 1,000 mL buckets
Maximum included rotor capacity of 4 × 1,000 mL
Included TX-1000 rotor maximum speed of 4,200 RPM
Included rotor maximum RCF of 4,122 × g
Maximum platform speed of 15,200 RPM with compatible fixed-angle rotor
Maximum platform RCF of 25,830 × g with appropriate rotor
Refrigerated temperature range from -10°C to +40°C
Large touchscreen interface with intuitive programming
Up to 100 stored programs
Nine acceleration and ten deceleration profiles
Thermo Scientific Auto-Lock III rotor exchange system
SMARTSpin imbalance detection and rotor management
Brushless induction drive motor
Compatible with a broad selection of Thermo Scientific rotors
Optional ClickSeal biocontainment lids and tube adapters
Refurbished and tested by American Instrument Exchange
90-day warranty included

Overview of the Thermo Scientific X4R Pro-MD

The Thermo Scientific Multifuge X4R Pro-MD is designed to accommodate a broad range of centrifugation applications while maintaining a relatively compact benchtop footprint.

Its maximum swinging-bucket capacity of 4 liters makes it particularly useful for laboratories processing large numbers of samples or working with high-volume biological preparations.

The instrument's refrigerated chamber provides controlled operating conditions for temperature-sensitive samples, while its advanced motor and control system support precise acceleration, deceleration, and run programming.

The X4R Pro-MD features a touchscreen interface that allows operators to create and store frequently used centrifugation protocols. This is especially useful in shared laboratories where different researchers require consistent operating parameters.

The centrifuge is part of Thermo Scientific's Pro series, which emphasizes intuitive controls, rotor flexibility, and streamlined sample processing.

With the included TX-1000 rotor and four buckets, this particular refurbished unit is configured for high-capacity swinging-bucket centrifugation.

Thermo Scientific Multifuge X4R Pro-MD Refrigerated Centrifuge Common Applications

The Thermo Scientific X4R Pro-MD is well suited for clinical laboratory testing, blood sample processing, cell culture research, biotechnology development, pharmaceutical research, microbiology, and general biological sample preparation.

Common applications include separation of blood components, harvesting cultured cells, processing bacterial suspensions, preparing biological samples for downstream analysis, separating cellular fractions, and centrifuging larger sample volumes.

The included TX-1000 rotor is particularly useful for laboratories requiring high-throughput processing of multiple sample containers.

With appropriate adapters, the rotor can accommodate different tube sizes and configurations, making it useful for laboratories processing blood collection tubes, 15 mL and 50 mL conical tubes, and other compatible vessels.

Additional rotor options allow the centrifuge to support applications requiring higher centrifugal forces or smaller sample volumes.

Included TX-1000 Swinging-Bucket Rotor and Buckets

This refurbished Thermo Scientific X4R Pro-MD includes the TX-1000 swinging-bucket rotor assembly and four compatible 1,000 mL buckets.

The TX-1000 rotor provides a maximum total capacity of 4 liters, making it suitable for high-volume laboratory sample processing.

When installed in the refrigerated X4R Pro-MD, the TX-1000 operates at speeds up to 4,200 RPM and generates centrifugal forces up to 4,122 × g.

During centrifugation, the buckets swing outward into a horizontal position, directing sedimentation toward the bottom of the sample containers.

This configuration is particularly useful for blood processing, cell harvesting, and other procedures where consistent separation and pellet positioning are important.

The TX-1000 rotor assembly consists of a rotor cross and four removable buckets. Thermo Scientific identifies the rotor cross as catalog number 75003017 and the bucket set as catalog number 75003001.

The rotor supports interchangeable adapters for various tube formats, allowing laboratories to configure the system for specific sample-processing requirements.

Optional ClickSeal biocontainment lids are available for applications requiring aerosol-tight containment when properly installed and maintained.

This refurbished configuration includes the TX-1000 rotor and four buckets. Tube adapters, ClickSeal lids, and other accessories are not included unless specifically listed.

Rotor Compatibility and Additional Applications

One of the principal advantages of the Thermo Scientific X4R Pro-MD is its broad rotor compatibility.

The centrifuge supports up to 18 rotor options, including swinging-bucket and fixed-angle configurations designed for different laboratory applications.

With appropriate fixed-angle rotors, the centrifuge can achieve maximum speeds of 15,200 RPM and centrifugal forces up to 25,830 × g.

These higher specifications represent the maximum capabilities of the centrifuge platform and do not apply to the included TX-1000 swinging-bucket rotor.

Compatible rotor configurations allow laboratories to process microcentrifuge tubes, conical tubes, centrifuge bottles, blood collection tubes, and microplates.

The Auto-Lock III rotor exchange system simplifies installation and removal of compatible rotors without tools.

This flexibility makes the X4R Pro-MD suitable for shared laboratory environments and facilities whose sample-processing requirements change over time.

Additional compatible rotors and accessories may be available separately from American Instrument Exchange. Customers should contact AIE to discuss current inventory and compatibility.

Thermo Scientific Multifuge X4R Pro-MD Refrigerated Centrifuge Key Specifications

Specification	Details
Manufacturer	Thermo Scientific
Model	Multifuge X4R Pro-MD
Condition	Used / Refurbished
Centrifuge Type	Refrigerated Multipurpose Benchtop
Included Rotor	TX-1000 Swinging-Bucket Rotor
Rotor Cross Catalog Number	75003017
Included Buckets	Four TX-1000 Buckets
Bucket Set Catalog Number	75003001
Maximum Included Rotor Capacity	4 × 1,000 mL
Included Rotor Maximum Speed	4,200 RPM
Included Rotor Maximum RCF	4,122 × g
Maximum Platform Speed	15,200 RPM, Rotor Dependent
Maximum Platform RCF	25,830 × g, Rotor Dependent
Maximum Swinging-Bucket Capacity	4 Liters
Temperature Range	-10°C to +40°C
Compatible Rotor Options	Up to 18
Acceleration Profiles	9
Deceleration Profiles	10
Program Storage	Up to 100 Programs
Control Interface	Touchscreen
Drive System	Direct Brushless Induction
Rotor Exchange System	Auto-Lock III
Imbalance Detection	SMARTSpin
Timer	Up to 99 Hours, 59 Minutes, 59 Seconds, Plus Hold
Exterior Width	Approximately 29.3"
Exterior Depth	Approximately 26.4"
Exterior Height	Approximately 14.2"
Weight Without Rotor	Approximately 256 lb
Electrical Requirements	Verify Instrument Nameplate; 120V and 220–240V Configurations Available
Tube Adapters	Available Separately Unless Specified
ClickSeal Lids	Optional; Confirm Inclusion
Warranty	90 Days

Specifications compiled from Thermo Scientific manufacturer literature and technical documentation. Maximum speed and centrifugal force depend on the installed rotor. The included TX-1000 rotor is rated for 4,200 RPM and 4,122 × g in the X4R Pro-MD.

Refrigeration and Temperature Stability

The Thermo Scientific X4R Pro-MD incorporates an advanced refrigeration system designed to maintain controlled chamber temperatures during centrifugation.

The instrument provides an adjustable temperature range from -10°C to +40°C, allowing laboratories to select conditions appropriate for different biological samples.

Refrigeration is particularly important when processing temperature-sensitive proteins, enzymes, blood components, cultured cells, and other biological materials that may be affected by heat generated during centrifugation.

The instrument's temperature controls help maintain consistent operating conditions throughout repeated laboratory procedures.

Actual sample temperature depends on rotor selection, operating speed, sample load, ambient conditions, and run duration.

The combination of refrigeration and high-capacity swinging-bucket centrifugation makes the X4R Pro-MD particularly useful for laboratories processing substantial quantities of biological samples.

Touchscreen Controls and Programmable Operation

The Thermo Scientific X4R Pro-MD features a large touchscreen interface designed to simplify centrifuge programming and routine operation.

Users can select operating speed, centrifugal force, temperature, acceleration, braking, and run duration through the control system.

The centrifuge supports storage of up to 100 programs, allowing laboratories to save frequently used protocols for repeatable operation.

Nine acceleration and ten deceleration profiles provide flexibility for applications requiring different levels of sample handling.

Gentler acceleration and braking settings can be useful for procedures involving delicate pellets or density-sensitive separations.

The touchscreen interface also supports multi-step programming, allowing laboratories to establish more complex centrifugation procedures when required.

These capabilities are particularly valuable in shared laboratory environments where multiple operators need consistent access to established protocols.

Auto-Lock III Rotor Exchange and SMARTSpin Technology

The X4R Pro-MD incorporates Thermo Scientific's Auto-Lock III rotor exchange system, allowing compatible rotors to be installed and removed without tools.

This simplifies rotor changes and reduces setup time when switching between different sample formats.

SMARTSpin technology monitors operating conditions and supports safe centrifugation through automatic rotor management and imbalance detection.

Together, these systems help improve operating convenience and reduce the potential for setup errors.

For laboratories performing different centrifugation procedures throughout the day, these features allow the X4R Pro-MD to serve as a versatile shared instrument.

Refurbishment and Testing

American Instrument Exchange technicians inspect and evaluate refurbished laboratory centrifuges before shipment to verify proper mechanical and electrical operation.

Testing includes evaluation of the drive motor, spindle assembly, braking system, touchscreen controls, rotor recognition, lid safety mechanisms, and overall operating performance.

Because the X4R Pro-MD is refrigerated, technicians also evaluate the cooling system to verify that the instrument reaches and maintains appropriate operating temperatures.

The included TX-1000 rotor and four buckets are inspected for visible damage, wear, corrosion, and proper fit.

The rotor and centrifuge are evaluated together to verify their operation as a complete system.

The instrument is cleaned and prepared for shipment after refurbishment and testing.

This refurbished Thermo Scientific Multifuge X4R Pro-MD includes a 90-day warranty from American Instrument Exchange.

Shipping and Installation

The Thermo Scientific X4R Pro-MD is a substantial benchtop centrifuge measuring approximately 29.3 inches wide × 26.4 inches deep × 14.2 inches high.

The instrument weighs approximately 256 pounds without a rotor, requiring a sturdy laboratory bench or dedicated centrifuge stand capable of supporting its operating weight.

The centrifuge is available from the manufacturer in different electrical configurations, including 120V and higher-voltage versions. Customers should verify the electrical requirements of the specific refurbished unit before installation.

Adequate ventilation clearance should be maintained around the instrument to support refrigeration performance.

Because of its weight, the X4R Pro-MD is typically shipped using palletized freight with appropriate protection for the instrument, rotor, buckets, and electronic controls.

American Instrument Exchange prepares refurbished laboratory equipment for secure shipment and can assist customers with freight coordination and installation planning.

Related Laboratory Equipment

American Instrument Exchange offers a broad selection of used and refurbished laboratory centrifuges, including Thermo Scientific multipurpose centrifuges, refrigerated benchtop centrifuges, microcentrifuges, and high-speed floor-model systems.

Laboratories performing biotechnology, molecular biology, and cell culture research may also be interested in our selection of laboratory incubators, laboratory freezers and ultra-low freezers, and biosafety cabinets.

Additional compatible rotors, buckets, and tube adapters may be available from American Instrument Exchange. Contact our sales team for current availability.

Service and Support

American Instrument Exchange provides diagnostic evaluation, preventative maintenance, and repair support for centrifuges and other laboratory equipment.

For the Thermo Scientific X4R Pro-MD, service evaluation may include the drive motor, spindle assembly, bearings, braking system, refrigeration components, temperature sensors, touchscreen controls, rotor locking mechanism, and electronic safety systems.

Our technicians can help laboratories determine whether repair or replacement with another refurbished centrifuge is the more economical solution.

Thermo Scientific X4R Pro-MD Frequently Asked Questions

What rotor is included with this refurbished Thermo Scientific X4R Pro-MD?

This refurbished centrifuge includes the Thermo Scientific TX-1000 swinging-bucket rotor with four compatible 1,000 mL buckets.

What is the maximum capacity of the included TX-1000 rotor?

The TX-1000 provides a maximum total capacity of 4 liters, consisting of four 1,000 mL buckets.

What is the maximum speed of the TX-1000 rotor?

When installed in the refrigerated X4R Pro-MD, the TX-1000 operates at speeds up to 4,200 RPM and generates centrifugal forces up to 4,122 × g.

Can the X4R Pro-MD reach higher speeds with other rotors?

Yes. With appropriate compatible fixed-angle rotors, the X4R Pro-MD can reach speeds up to 15,200 RPM and centrifugal forces up to 25,830 × g.

Are tube adapters included with the TX-1000 buckets?

The included configuration consists of the TX-1000 rotor and four buckets. Tube adapters are not assumed to be included unless specifically listed. Compatible adapters may be available separately.

Are the TX-1000 buckets aerosol-tight?

The TX-1000 supports optional ClickSeal biocontainment lids that provide aerosol-tight containment when properly installed and maintained. Standard buckets should not be assumed to provide aerosol-tight containment without the appropriate lids.

Can the X4R Pro-MD process blood collection tubes?

Yes. With appropriate tube adapters, the TX-1000 rotor can accommodate a variety of blood collection tube formats, making the centrifuge useful for clinical laboratory applications.

Can this centrifuge accommodate 15 mL and 50 mL conical tubes?

Yes. The TX-1000 rotor supports compatible adapters for 15 mL and 50 mL conical tubes. The correct adapters must be selected for the specific tube dimensions and application.

What is the temperature range of the X4R Pro-MD?

The refrigerated centrifuge provides an adjustable temperature range from -10°C to +40°C.

What is the difference between the X4 Pro-MD and X4R Pro-MD?

The X4 Pro-MD is the non-refrigerated version, while the X4R Pro-MD includes an integrated refrigeration system. The refrigerated model is particularly useful for temperature-sensitive biological samples.

What is the Auto-Lock III rotor exchange system?

Auto-Lock III allows compatible rotors to be installed and removed without tools, simplifying rotor changes and reducing setup time.

Are additional rotors available for the X4R Pro-MD?

The centrifuge supports a broad range of compatible Thermo Scientific rotors. Additional rotors and accessories may be available separately from American Instrument Exchange.

What electrical service is required?

The X4R Pro-MD is available in different electrical configurations, including 120V and 220–240V versions. Customers should verify the electrical specifications of the particular refurbished instrument before installation.

Why purchase a refurbished Thermo Scientific X4R Pro-MD?

A professionally refurbished X4R Pro-MD provides high-capacity refrigerated centrifugation, touchscreen programming, and extensive rotor flexibility at a lower acquisition cost than comparable new equipment.

With the included TX-1000 rotor and four 1,000 mL buckets, this configuration is particularly useful for laboratories processing large sample volumes or requiring flexible swinging-bucket centrifugation.

This refurbished centrifuge includes a 90-day warranty from American Instrument Exchange.

Testing Procedures for Used and Refurbished Laboratory Centrifuges

Ensure Quality, Accuracy, and Compliance Before Deployment

Used and refurbished laboratory centrifuges from American Instrument Exchange undergo testing procedures to ensure they meet the performance, safety, and compliance standards required in modern laboratories.

Why Testing Used Laboratory Centrifuges Is Essential

Before a centrifuge is reintroduced into a lab environment, it must be tested for:

Mechanical integrity
Rotor balance and speed accuracy
Safety system functionality
Electrical compliance

Proper testing helps extend equipment lifespan, reduce downtime, and ensure safety in high-stakes lab environments such as clinical diagnostics, biotechnology, and research applications.

Our structured testing protocol for used and refurbished centrifuges ensures equipment safety, accuracy, and longevity.

Key Testing Procedures for Refurbished and Used Centrifuges

1. Initial Visual Inspection

Check for signs of wear, corrosion, or damage to housing, lid, and control panels
Inspect power cords, plugs, and connectors for fraying or exposed wiring
Confirm that the rotor and accessories are compatible and undamaged

2. Functional Testing

Power up the centrifuge and confirm successful boot-up of digital or analog displays
Test lid lock and emergency stop mechanisms
Run initial cycles at various speeds to check for abnormal noise or vibration

3. Rotor and Speed Verification

Test all programmable speed settings to confirm consistent acceleration and deceleration
Monitor temperature, vibration, and RPM consistency throughout the cycle
Balance testing ensures smooth operation and prevents wear on internal components

4. Electrical Safety and Grounding Tests

Verify that all electrical components are properly grounded and shielded

5. Temperature Control (if applicable)

For refrigerated centrifuges, test cooling function to ensure temperature stability within set ranges
Check refrigerant levels and inspect for compressor noise or failure

6. Final Quality Assurance Checklist

Conduct a full run-through using the user interface
Document all test results

Repair and Refurbishment Protocol for Used Laboratory Centrifuges

Certified Quality from American Instrument Exchange

At American Instrument Exchange, we follow a meticulous repair and refurbishment protocol to ensure that every used laboratory centrifuge we sell. We strive for reliable performance and long-term durability—providing labs with exceptional value on high-quality pre-owned centrifuges.

Why Choose a Refurbished Centrifuge from American Instrument Exchange?

Fully tested
Backed by warranty and performance guarantee
Cost-effective alternative to new lab equipment
Environmentally responsible through equipment reuse
Supported by expert technicians with decades of experience

Step-by-Step Refurbishment Protocol

Every used centrifuge at American Instrument Exchange goes through the following comprehensive repair and refurbishment process:

1. Initial Intake & Inspection

Our technicians perform a complete visual and mechanical inspection
Evaluation of hinges, seals, gaskets, and electrical components
Any physical damage, missing parts, or wear is documented for repair

2. Cleaning and decontamination

Full internal and external cleaning using non-abrasive, disinfectant-safe products
Biological or chemical residue is decontaminated/cleaned

3. Mechanical & Electrical Repairs

Damaged or worn parts (e.g., drive motors, lid latches, rotor buckets) are replaced or repaired
Electrical components, sensors, and fuses are tested and replaced as needed
Wiring is inspected for integrity and safety per industry standards

4. Rotor & Accessory Evaluation

All rotors, buckets, and adapters are inspected for cracks, corrosion, and balance
Non-conforming components are replaced with OEM or equivalent alternatives

5. Performance Testing

Rotor speed (RPM), acceleration, and deceleration are verified
Refrigerated centrifuges undergo temperature stability testing across set ranges

6. Safety System Verification

Lid lock and interlock systems are tested for proper function
Emergency stop and imbalance detection systems are verified
Electrical safety and grounding tests are conducted

Trust the Experts at American Instrument Exchange

With over 50 years of experience in the industry, American Instrument Exchange is a trusted name for refurbished lab equipment. Our centrifuge refurbishment protocol reflects our commitment to quality, safety, and customer satisfaction.

Warranty Information

All used equipment sold by American Instrument Exchange is refurbished/reconditioned, tested to meet specifications, cleaned, and comes with a 90-day warranty from the date of shipment unless otherwise specified. New products include a warranty from the manufacturer. Your warranty is only valid if you have paid your invoice. If your invoice is over 30 days old, warranty work will not be performed until your invoice is paid in full. American Instrument Exchange is not liable for any special or consequential damages that result from the use of, or the inability to use, the materials on this site or the performance of the products,

Exceptions include international sales and items that are agreed to be sold with a lesser warranty or items that are agreed to be sold “as is.”

Should there be visible shipping damage to packaging or concealed shipping damage to item(s) supplied, buyer must communicate such damage to the delivering entity or carrier upon receipt first and to American Instrument the same day item is accepted / signed for. Failure to do so voids warranty. Customer decision to involve / procure third party or OEM service other than American Instrument or AIE assigned vendors to resolve in-warranty instrument failure or defect without first placing a service call to American Instrument voids warranty.

Return & Cancellation Policy

American Instrument Exchange will authorize the return of and issue a full refund for any equipment that is not working as represented and could not be replaced or repaired to the customer’s satisfaction by AIE or a representative of AIE during the warranty period. Returns without prior authorization and an RMA number will not be accepted.

Customers are responsible for proper packaging of the equipment and all included accessories. American Instrument will pay for insurance and shipping costs. Non-inventory items bought specifically to fill customer orders may possibly be returned, but on a case by case basis.

Customers who cancel orders after refurbishing has begun or after delivery where there are no equipment performance issues may be subject to a Restocking/Cancellation Fee of 20% or more and responsible for shipping costs for both the delivery and return.

Ongoing and Extended Support Options

American Instrument Exchange is able to provide additional repair and support services outside the warranty terms for most products that sell.

For biosafety cabinets, clean benches, chemical fume hoods, and other clean air products our team at AIE Laboratory Services can provide certifications, repairs, decontaminations, and other services for customers throughout New England, and guidance and limited technical assistance for any customers in the US and Canada for new or refurbished biosafety cabinets purchased from American Instrument Exchange.

For all other products, the repair service team at American Instrument Exchange can provide both field and depot repair evaluations. We can easily schedule and coordinate the pick-up and transportation of your malfunctioning equipment. By offering hourly rates lower than most OEM service providers and eliminating travel time for technicians, we help reduce repair costs. Furthermore, our lab depot repair service minimizes or eliminates scheduling delays. Our experienced service technicians are qualified to restore your equipment to factory specifications.

Please contact our team at info@americaninstrument.com for more details.

FAQ

Does the equipment come with a warranty?

Yes, all equipment from American Instrument Exchange comes with a warranty.
Used/reconditioned/refurbished equipment is tested to make sure it operates to the manufacturer's specifications and comes with a 90-day warranty (unless otherwise noted). New equipment comes with a warranty from the manufacturer.

How do you test and recondition the equipment?

Testing requirements vary across all the equipment categories we sell. Temperature controlled units are tested with NIST traceable probes and data loggers. Gaskets, external housing, glass, handles, controls and control screens are all thoroughly inspected for integrity and functionality.
We test all equipment using the manufacturer's parameters and specifications to confirm that the unit operates properly.

How do products ship from American Instrument Exchange?

We can ship products both nationally and internationally using a well-established network of transporters. Smaller items will ship via UPS. Larger equipment will be palletized and shipped either LTL or air-ride, depending on the specific equipment and/or delivery requirements.

Return and order cancellation policy

American Instrument Exchange will accept the return of any product that is not working as represented and could not be replaced or repaired to the customer's satisfaction during the warranty period. Customers who cancel orders after refurbishing has begun will be subject to a cancellation and restocking fee of between 20% and 40%.

Are discounts available for educational or non-profit institutions, or for bulk purchases?

Yes – call or email us today with a list of equipment you're looking for and we can potentially put together a quote that includes a discount.

How does your price matching policy work?

We strive to keep our pricing competitive and reasonable. If you find comparable items for sale at a lower price from other vendors please send us a link and or quote for the item and we'll do our best to match or beat the price.

Can I see the equipment in person before committing to a purchase?

Customers are welcome to make an appointment to view equipment in our warehouse. Given our workload we may not be able to test or clean the equipment prior to your arrival if you have not committed to an order.

1023 Western Avenue is a working warehouse, not a showroom, and customers should dress appropriately and wear closed toe shoes.

Can I ship products that I purchased elsewhere to American Instrument for repair?

Yes – please see our repair services page for more information.