Thermo Scientific TSU300A Ultra-Low Temperature Freezer

Product Code : SKU 2546T FREEZER

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Thermo Scientific TSU300A Ultra-Low Temperature Freezer

Not every laboratory needs the largest ultralow freezer on the market, but every laboratory storing irreplaceable biological materials depends on dependable sample protection. The Thermo Scientific TSU300A Ultra-Low Temperature Freezer delivers reliable long-term preservation at temperatures as low as -86°C in a compact, energy-efficient platform designed for laboratories where both floor space and operating costs matter.

With 14.9 cubic feet (422 liters) of storage capacity and room for up to 300 standard 2-inch cryoboxes, the TSU300A is an excellent choice for biotechnology companies, pharmaceutical manufacturers, hospitals, universities, and research laboratories requiring dependable ultra-low temperature storage without the footprint of a larger cabinet.

Laboratories building a complete cold storage program often pair ultralow freezers with laboratory refrigerators for day-to-day reagent storage and laboratory freezers for materials that do not require -80°C preservation. Purchasing a professionally refurbished unit from American Instrument Exchange allows laboratories to acquire premium laboratory equipment while reducing capital expenditures.

Thermo Scientific TSU300A Ultra-Low Temperature Freezer Key Features

14.9 cu. ft. (422 L) storage capacity
Holds up to 300 standard 2-inch cryoboxes
Adjustable operating temperature from -50°C to -86°C
Natural hydrocarbon refrigeration technology
Vacuum insulation panel construction
Touchscreen user interface
Manual defrost operation
Multiple insulated inner doors
Advanced alarm and monitoring system
Refurbished and performance tested by American Instrument Exchange
90-day warranty included

Thermo Scientific TSU300A Ultra-Low Temperature Freezer Overview

The TSU300A was developed for laboratories that need dependable ultra-low temperature storage while making the most of available laboratory space. Its hydrocarbon refrigeration system and vacuum insulation technology provide stable long-term storage conditions while reducing energy consumption and laboratory heat output compared with many previous-generation ULT freezers. The result is dependable sample protection in a cabinet sized for departmental laboratories, satellite research facilities, and growing research programs.

Modern laboratory workflows rarely depend on a single instrument. Samples are commonly prepared inside biosafety cabinets, cultured in CO₂ incubators, processed using refrigerated centrifuges, and ultimately transferred into an ultralow freezer for long-term preservation. The TSU300A provides the dependable final stage of that workflow, protecting valuable research materials long after the experiment has been completed.

Common Applications

The Thermo Scientific TSU300A is commonly used for long-term preservation of DNA and RNA libraries, stem cells, cell lines, tissue specimens, plasma, serum, vaccines, pharmaceutical compounds, microbiological collections, forensic evidence, clinical trial materials, and biological reference standards requiring storage at temperatures as low as -86°C.

Its 300-box capacity makes it particularly well suited for hospital laboratories, university departments, biotechnology startups, pharmaceutical development laboratories, and research groups that require dependable ultra-low storage without dedicating space to a larger 400- or 600-box platform. Laboratories requiring colder storage than traditional laboratory freezers often select ultralow freezers to provide an additional level of protection for irreplaceable biological collections.

Ideal Laboratory Types

The TSU300A is well suited for:

Biotechnology laboratories
Pharmaceutical manufacturers
Academic research institutions
Hospitals and clinical laboratories
Public health laboratories
Government research facilities
Contract research organizations
University research groups
Cell culture laboratories

Its compact footprint and dependable performance make it an excellent choice for laboratories expanding ultra-low temperature storage while preserving valuable floor space.

Temperature Recovery & Sample Protection

Protecting valuable biological materials requires more than simply maintaining a set temperature. The TSU300A is engineered to recover quickly following routine door openings while minimizing unnecessary warming of neighboring samples. Multiple insulated inner doors reduce cold air loss during sample retrieval, allowing laboratory personnel to access only one section of the cabinet while helping maintain stable storage temperatures throughout the remainder of the freezer.

Vacuum insulation panels improve thermal performance while maximizing usable storage space inside the cabinet. Many laboratories preserving especially valuable biological collections also incorporate cryogenic storage systems into their preservation strategy. While ultralow freezers are ideal for routine long-term storage, cryogenic systems provide an additional option for applications requiring liquid nitrogen temperatures and extended biological preservation.

Typical Stored Materials

The Thermo Scientific TSU300A is commonly used to store:

DNA and RNA libraries
Cell lines
Stem cells
Tissue specimens
Plasma and serum
Vaccines
Protein samples
Enzymes
Pharmaceutical compounds
Clinical trial materials
Microbial cultures
Biological reference materials

Thermo Scientific TSU300A Ultra-Low Temperature Freezer Key Specifications

Capacity

14.9 cu. ft. (422 L)
Up to 300 standard 2-inch cryoboxes

Temperature Range

Adjustable from -50°C to -86°C

Refrigeration System

Hydrocarbon refrigeration system
Manual defrost
Vacuum insulation panel construction

Monitoring & Controls

Touchscreen user interface
Electronic microprocessor controls
Alarm and monitoring system

Interior Configuration

Multiple insulated inner doors
Compatible with standard cryobox storage racks

Electrical Requirements

115V, 60 Hz

Dimensions

Approximately 32.4" W × 37.6" D × 78" H

Weight

Approximately 610 lbs.

Energy Efficiency & Operating Costs

Ultra-low freezers operate continuously, making energy consumption one of the largest contributors to laboratory operating costs. The TSU300A combines natural hydrocarbon refrigerants with vacuum insulation technology to reduce electrical consumption while minimizing heat released into the laboratory. Lower heat rejection can reduce HVAC demand, improve laboratory comfort, and contribute to lower operating costs for facilities operating multiple pieces of cold storage equipment. For laboratories replacing older cascade-refrigerant ULT freezers, the TSU300A offers an opportunity to improve efficiency while maintaining dependable sample protection.

Specifications compiled from Thermo Scientific manufacturer literature and American Instrument Exchange product information.

Refurbishment & Testing Process

Every Thermo Scientific TSU300A received by American Instrument Exchange undergoes a comprehensive inspection and extended performance evaluation before shipment. Our technicians verify pull-down performance, confirm stable operation throughout the operating temperature range, inspect the refrigeration system and compressors, evaluate door gaskets and cabinet insulation, test alarms and electronic controls, verify temperature stability, and thoroughly clean the freezer before delivery.

Laboratories outfitting an entire facility frequently combine refurbished ultralow freezers with laboratory refrigerators, biosafety cabinets, CO₂ incubators, and refrigerated centrifuges to create a complete laboratory equipment solution while reducing overall capital expenditures.

Shipping & Installation Considerations

The Thermo Scientific TSU300A ships by freight from American Instrument Exchange. Before delivery, laboratories should verify doorway clearances, electrical service, floor loading capacity, and adequate ventilation around the cabinet. Its compact footprint makes installation easier in laboratories where space is limited while still providing substantial ultra-low temperature storage capacity.

Frequently Asked Questions

How many cryoboxes can the TSU300A hold?

The TSU300A accommodates up to 300 standard 2-inch cryoboxes, making it an excellent choice for laboratories requiring substantial storage capacity in a compact footprint.

Why are vacuum insulation panels important?

Vacuum insulation panels improve thermal performance while reducing cabinet wall thickness, allowing more usable storage space within the same laboratory footprint.

What types of laboratories commonly use this freezer?

The TSU300A is widely used in biotechnology, pharmaceutical, academic, clinical, and government research laboratories requiring dependable ultra-low temperature preservation.

How is the freezer tested before shipment?

Every refurbished TSU300A is inspected, cleaned, and performance tested by American Instrument Exchange technicians to verify pull-down performance, temperature stability, alarm functionality, and overall system operation before shipment.

Testing Procedures for Used and Refurbished Ultralow Freezers
Ensure -80°C Stability and Critical Sample Protection

Used and refurbished ultralow freezers from American Instrument Exchange are rigorously tested to ensure reliable long-term storage at temperatures as low as -80°C. Each unit undergoes a detailed inspection, full system evaluation, and extended runtime testing to meet the high standards required by research, clinical, and biorepository environments.

Why Testing Used Ultralow Freezers Is Essential

Before an ultralow freezer is placed back into service, it must be carefully tested for:
• Temperature stability and uniformity at ultralow levels (e.g., -70°C to -86°C)
• Cascade refrigeration system functionality and compressor health
• Seal and insulation effectiveness to prevent thermal loss
• Electrical safety, alarm functionality, and system compliance

Thorough testing helps prevent temperature excursions and equipment failure—crucial for protecting sensitive materials such as biological samples, vaccines, enzymes, and research specimens.
Our structured ULT testing protocol ensures each refurbished unit delivers dependable performance and long-term reliability.

Key Testing Procedures for Refurbished and Used Ultralow Freezers

1. Initial Visual Inspection

• Inspect external cabinet, hinges, and door gaskets for wear, corrosion, or damage
• Check power cords, plugs, and control interfaces for signs of wear or tampering
• Verify that internal racks, shelving, and chamber components are intact and operational

2. Functional Startup and Control Testing

• Power on the unit and confirm successful initialization of digital displays and alarm systems
• Test control panels, keypad responsiveness, and user-setpoint functionality
• Verify that door seals close tightly and form a secure barrier

3. Temperature and -80°C Stability Testing

• Test and evaluate internal temperature sensors thermometers/probes
• Monitor temperature performance at multiple chamber points over extended runtimes
• Confirm uniformity and stability at key setpoints, including -70°C, -80°C, and -86°C

4. Refrigeration System and Cascade Compressor Evaluation

• Test dual-stage (cascade) compressor function, startup times, and cycling behavior
• Evaluate evaporator coils, heat exchangers, and vacuum insulation panels for performance and integrity
• Check for refrigerant leaks, low-pressure faults, and abnormal compressor noise

5. Alarm and Safety System Verification

• Test high/low temperature alarms, power failure alerts, and battery backup systems (if equipped)
• Verify lockout controls, alarm delay settings, and door-open indicators

6. Final Quality Assurance and Documentation

• Run a continuous multi-day test cycle at -80°C to confirm sustained performance
• Document temperature logs, controller accuracy, and compressor behavior
• Complete a detailed service report

Dependable Performance from American Instrument Exchange

All refurbished ultralow freezers from American Instrument Exchange are tested to exacting standards for performance, safety, and reliability. With our rigorous inspection and testing procedures, you can trust your ULT freezer to deliver consistent -80°C storage from day one—ideal for research, clinical, pharmaceutical, and biobanking applications.

Repair and Refurbishment Protocol for Used Ultralow Freezers
-80°C Storage Performance from American Instrument Exchange

At American Instrument Exchange, every used ultralow temperature freezer (ULT freezer) undergoes a rigorous, multi-step refurbishment protocol designed to restore reliable -80°C performance. Whether upright, chest-style, or undercounter, our refurbished ULT freezers are tested and restored to deliver the cold storage precision required for biological samples, vaccines, enzymes, and other temperature-sensitive materials.

Why Choose a Refurbished Ultralow Freezer from American Instrument Exchange?

• Fully tested for -80°C cold storage stability and compressor performance
• Backed by a warranty
• A cost-effective alternative to expensive new ULT units
• Environmentally responsible through equipment reuse and waste reduction
• Serviced by experienced technicians specializing in laboratory-grade refrigeration

Step-by-Step Ultralow Freezer Refurbishment Protocol

Every ultralow freezer sold by American Instrument Exchange is carefully evaluated and restored through the following process:

1. Initial Intake & Inspection

• Exterior inspection for dents, corrosion, or physical damage
• Evaluation of door seals, hinges, and internal chamber components
• Documentation of missing parts or components requiring repair

2. Cleaning and Decontamination

• Comprehensive interior and exterior cleaning using non-abrasive cleaners
• Removal of dust, frost buildup, and residual contaminants
• Decontamination of all internal surfaces and removable parts like shelves and drawers

3. Mechanical and Electrical Repairs

• Replacement or repair of worn or damaged components (door latches, hinges, gaskets, etc.)
• Inspection and repair of control boards, displays, sensors, and switches
• Electrical system evaluation, including fuses, wiring, relays, and connectors

4. Ultralow Refrigeration System Assessment

• Testing of dual-stage compressors and cascade cooling system
• Evaluation of heat exchangers, evaporator coils, and vacuum insulation panels
• Inspection for refrigerant leaks, low pressure, or signs of compressor fatigue
• Verification of thermal insulation integrity

5. Temperature and Performance Testing

• Testing of internal temperature sensors and controllers
• Multi-point testing to verify chamber temperature uniformity at -80°C
• Long-duration, multi-day operational testing to ensure sustained ultralow performance

6. Safety and Compliance Checks

• Electrical safety testing and grounding verification
• Alarm function tests for high/low temperature alerts and power failure warnings

7. Final Quality Control and Documentation

• Multi-day runtime validation at -80°C
• Recording of temperature logs, compressor cycle data, and performance benchmarks
• Final inspection and service/testing report completed

Trust the Experts at American Instrument Exchange

With over 50 years in the lab equipment industry, American Instrument Exchange is your trusted source for refurbished ultralow freezers. Our certified refurbishment protocol ensures each ULT freezer delivers the precision, performance, and reliability your lab needs—at a fraction of the cost of new equipment.

Warranty Information

All used equipment sold by American Instrument Exchange is refurbished/reconditioned, tested to meet specifications, cleaned, and comes with a 90-day warranty from the date of shipment unless otherwise specified. New products include a warranty from the manufacturer. Your warranty is only valid if you have paid your invoice. If your invoice is over 30 days old, warranty work will not be performed until your invoice is paid in full. American Instrument Exchange is not liable for any special or consequential damages that result from the use of, or the inability to use, the materials on this site or the performance of the products,

Exceptions include international sales and items that are agreed to be sold with a lesser warranty or items that are agreed to be sold “as is.”

Should there be visible shipping damage to packaging or concealed shipping damage to item(s) supplied, buyer must communicate such damage to the delivering entity or carrier upon receipt first and to American Instrument the same day item is accepted / signed for. Failure to do so voids warranty. Customer decision to involve / procure third party or OEM service other than American Instrument or AIE assigned vendors to resolve in-warranty instrument failure or defect without first placing a service call to American Instrument voids warranty.

Return & Cancellation Policy

American Instrument Exchange will authorize the return of and issue a full refund for any equipment that is not working as represented and could not be replaced or repaired to the customer’s satisfaction by AIE or a representative of AIE during the warranty period. Returns without prior authorization and an RMA number will not be accepted.

Customers are responsible for proper packaging of the equipment and all included accessories. American Instrument will pay for insurance and shipping costs. Non-inventory items bought specifically to fill customer orders may possibly be returned, but on a case by case basis.

Customers who cancel orders after refurbishing has begun or after delivery where there are no equipment performance issues may be subject to a Restocking/Cancellation Fee of 20% or more and responsible for shipping costs for both the delivery and return.

Ongoing and Extended Support Options

American Instrument Exchange is able to provide additional repair and support services outside the warranty terms for most products that sell.

For biosafety cabinets, clean benches, chemical fume hoods, and other clean air products our team at AIE Laboratory Services can provide certifications, repairs, decontaminations, and other services for customers throughout New England, and guidance and limited technical assistance for any customers in the US and Canada for new or refurbished biosafety cabinets purchased from American Instrument Exchange.

For all other products, the repair service team at American Instrument Exchange can provide both field and depot repair evaluations. We can easily schedule and coordinate the pick-up and transportation of your malfunctioning equipment. By offering hourly rates lower than most OEM service providers and eliminating travel time for technicians, we help reduce repair costs. Furthermore, our lab depot repair service minimizes or eliminates scheduling delays. Our experienced service technicians are qualified to restore your equipment to factory specifications.

Please contact our team at info@americaninstrument.com for more details.

FAQ

Does the equipment come with a warranty?

Yes, all equipment from American Instrument Exchange comes with a warranty.
Used/reconditioned/refurbished equipment is tested to make sure it operates to the manufacturer's specifications and comes with a 90-day warranty (unless otherwise noted). New equipment comes with a warranty from the manufacturer.

How do you test and recondition the equipment?

Testing requirements vary across all the equipment categories we sell. Temperature controlled units are tested with NIST traceable probes and data loggers. Gaskets, external housing, glass, handles, controls and control screens are all thoroughly inspected for integrity and functionality.
We test all equipment using the manufacturer's parameters and specifications to confirm that the unit operates properly.

How do products ship from American Instrument Exchange?

We can ship products both nationally and internationally using a well-established network of transporters. Smaller items will ship via UPS. Larger equipment will be palletized and shipped either LTL or air-ride, depending on the specific equipment and/or delivery requirements.

Return and order cancellation policy

American Instrument Exchange will accept the return of any product that is not working as represented and could not be replaced or repaired to the customer's satisfaction during the warranty period. Customers who cancel orders after refurbishing has begun will be subject to a cancellation and restocking fee of between 20% and 40%.

Are discounts available for educational or non-profit institutions, or for bulk purchases?

Yes – call or email us today with a list of equipment you're looking for and we can potentially put together a quote that includes a discount.

How does your price matching policy work?

We strive to keep our pricing competitive and reasonable. If you find comparable items for sale at a lower price from other vendors please send us a link and or quote for the item and we'll do our best to match or beat the price.

Can I see the equipment in person before committing to a purchase?

Customers are welcome to make an appointment to view equipment in our warehouse. Given our workload we may not be able to test or clean the equipment prior to your arrival if you have not committed to an order.

1023 Western Avenue is a working warehouse, not a showroom, and customers should dress appropriately and wear closed toe shoes.

Can I ship products that I purchased elsewhere to American Instrument for repair?

Yes – please see our repair services page for more information.