Thermo Scientific TSX2305CA Chromatography Refrigerator

Brand : Thermo

Product Code : SKU 4393AA REFRIG

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Thermo Scientific TSX2305CA High-Performance Chromatography Refrigerator

Many chromatography systems perform best when operated in a temperature-controlled environment. The Thermo Scientific TSX2305CA High-Performance Chromatography Refrigerator is purpose-built for this application, providing a refrigerated workspace that allows HPLC, FPLC, protein purification, and other chromatography systems to operate while maintaining a stable cabinet temperature between 3°C and 7°C. Featuring V-drive variable-speed compressor technology, the TSX2305CA combines exceptional temperature uniformity with industry-leading energy efficiency, helping protect sensitive samples while reducing operating costs.

With a 23 cubic foot (650 L) capacity, the TSX2305CA provides ample room for chromatography instrumentation, solvent reservoirs, tubing, columns, and associated laboratory equipment. Its triple-pane heated glass door allows researchers to monitor chromatography systems without opening the cabinet, minimizing temperature fluctuations while improving workflow. Whether supporting protein purification, antibody production, biopharmaceutical development, or analytical chemistry, the TSX2305CA delivers reliable refrigerated conditions for temperature-sensitive separations.

Many laboratories pair the TSX2305CA with ultra-low freezers for long-term sample preservation, laboratory freezers for intermediate storage, centrifuges for sample preparation, and biosafety cabinets to create a complete laboratory workflow.

Thermo Scientific TSX2305CA Key Features

Model / Catalog Number: TSX2305CA
23 cu. ft. (650 L) capacity
Temperature range: 3°C to 7°C (factory setpoint 5°C)
Designed specifically for chromatography instrumentation
V-drive variable-speed compressor technology
Triple-pane heated glass door
Automatic defrost
Microprocessor temperature controller
Digital temperature display
Two half-width shelves for flexible instrument placement
Compatible with Smart-Vue and DeviceLink monitoring
Natural R290 refrigerant
ENERGY STAR® certified
Refurbished and performance tested by American Instrument Exchange
90-day warranty included

Thermo Scientific TSX2305CA Overview

Unlike a traditional laboratory refrigerator intended solely for sample storage, the TSX2305CA is engineered to house and operate chromatography systems inside the refrigerated chamber. Running chromatography instruments at controlled temperatures helps preserve protein stability, improve reproducibility, and minimize degradation of temperature-sensitive compounds throughout lengthy purification or analytical runs.

Thermo Scientific's V-drive compressor continuously adjusts cooling capacity based on cabinet conditions. During heavy instrument operation or frequent door openings, compressor speed automatically increases to maintain stable temperatures. During periods of low demand, compressor speed decreases, reducing electrical consumption while maintaining outstanding temperature uniformity. With more than 450 watts of reserve refrigeration capacity, the TSX2305CA rapidly recovers after door openings or increased thermal loads.

Common Applications

The TSX2305CA is commonly used for:

HPLC systems
FPLC systems
ÄKTA protein purification systems
Protein purification
Antibody purification
Chromatography column storage
Enzyme purification
Biopharmaceutical development
Analytical chemistry
Bioprocess research

Ideal Laboratory Types

The TSX2305CA is an excellent choice for:

Biotechnology companies
Pharmaceutical manufacturers
Protein purification laboratories
Academic research laboratories
Bioprocess development facilities
Government research laboratories
Core laboratory facilities
Analytical chemistry laboratories

Laboratories operating chromatography equipment continuously will benefit from the refrigerator's combination of temperature stability, instrument visibility, and energy-efficient operation.

Why Choose a Chromatography Refrigerator?

Many chromatography separations require stable temperatures to maximize protein stability and improve analytical reproducibility. Rather than cooling only samples or reagents, a chromatography refrigerator cools the entire analytical system, including pumps, columns, tubing, and solvent reservoirs.

The TSX2305CA's glass door allows operators to monitor instrument status without disturbing the controlled environment, while the flexible shelving system accommodates a variety of chromatography configurations.

Typical Equipment Installed

The TSX2305CA commonly houses:

HPLC systems
FPLC systems
ÄKTA chromatography systems
Fraction collectors
Solvent reservoirs
Chromatography columns
Peristaltic pumps
Sample injection systems

Thermo Scientific TSX2305CA Key Specifications

Identification

Manufacturer: Thermo Scientific
Model / Catalog Number: TSX2305CA
Product Type: High-Performance Chromatography Refrigerator
Door Configuration: Single triple-pane glass door
Series: TSX High-Performance Chromatography Refrigerators

Capacity

23 cu. ft. (650 liters)

Temperature Range

3°C to 7°C
Factory setpoint: 5°C

Construction

Triple-pane heated glass door
Powder-coated steel cabinet
Two half-width adjustable shelves
Optimized for chromatography equipment

Refrigeration System

V-drive variable-speed compressor
Automatic defrost
Natural R290 refrigerant
Adaptive refrigeration control
Over 450 watts of reserve refrigeration capacity

Monitoring & Controls

Digital microprocessor controller
High/low temperature alarms
Smart-Vue compatible
DeviceLink compatible
Optional chart recorder
Remote alarm capability

Electrical Requirements

115V, 60 Hz
15 Amp circuit
NEMA 5-15 plug

Exterior Dimensions

37.8" D × 28.0" W × 78.5" H

Interior Dimensions

28.5" D × 24.0" W × 58.0" H

Weight

Approximately 439 lbs. (199 kg)

Operating Costs & Energy Considerations

The TSX2305CA combines Thermo Scientific's V-drive refrigeration technology with environmentally friendly R290 refrigerant to reduce energy consumption while maintaining outstanding temperature stability. The adaptive compressor automatically adjusts output based on actual demand, reducing operating costs during periods of low activity while providing rapid recovery when additional cooling capacity is needed. The refrigerator is ENERGY STAR certified, making it an excellent choice for laboratories seeking both performance and sustainability.

Specifications compiled from Thermo Scientific manufacturer literature and American Instrument Exchange product information.

Refurbishment & Testing Process

Every Thermo Scientific TSX2305CA received by American Instrument Exchange undergoes a comprehensive inspection before shipment. Our technicians verify refrigeration performance using calibrated temperature probes, inspect the V-drive compressor system, test alarms and controls, verify glass door integrity and shelving, and confirm temperature uniformity throughout the operating range. Each refrigerator is thoroughly cleaned and tested prior to shipment.

Laboratories building chromatography and protein purification facilities frequently purchase ultra-low freezers, laboratory freezers, centrifuges, biosafety cabinets, and additional laboratory refrigerators from American Instrument Exchange.

Shipping & Installation Considerations

The TSX2305CA ships by freight from American Instrument Exchange. Before installation, laboratories should verify doorway clearances, electrical service, and adequate ventilation around the cabinet. Allow the refrigerator to stabilize at operating temperature before installing chromatography instrumentation or loading temperature-sensitive materials.

Frequently Asked Questions

Can chromatography equipment operate inside the TSX2305CA?

Yes. The TSX2305CA is specifically designed to house and operate chromatography systems in a controlled refrigerated environment, helping improve reproducibility and protect temperature-sensitive samples.

Why does this model have a glass door?

The triple-pane heated glass door allows researchers to monitor chromatography systems without opening the cabinet, minimizing temperature fluctuations during long analytical runs.

What is the temperature range of the TSX2305CA?

The refrigerator is adjustable from 3°C to 7°C, with a factory setpoint of 5°C.

How is the TSX2305CA tested before shipment?

Every refurbished TSX2305CA is inspected and tested by American Instrument Exchange technicians to verify refrigeration performance, temperature accuracy, alarms, controls, and overall cabinet operation before shipment.

Testing Procedures for Used and Refurbished Laboratory Refrigerators
Ensure Temperature Stability and Cold Storage Accuracy

Used and refurbished laboratory refrigerators from American Instrument Exchange are thoroughly tested to ensure reliable cold storage performance, temperature accuracy, and compliance with laboratory safety and storage standards. Each unit undergoes a detailed inspection and functional verification to meet the requirements of clinical, pharmaceutical, research, and industrial labs.

Why Testing Used Laboratory Refrigerators Is Essential

Before a laboratory refrigerator is reintroduced into any laboratory setting, it must be carefully tested for:

• Temperature uniformity and stability
• Cooling system integrity and compressor function
• Door seal performance and insulation effectiveness
• Electrical safety and compliance with lab standards

Thorough testing minimizes the risk of temperature excursions, product loss, and system failures—especially critical for storing reagents, vaccines, biological samples, pharmaceuticals, and temperature-sensitive materials.

Our structured testing protocol ensures refurbished lab refrigerators deliver consistent, dependable performance across all makes and models.

Key Testing Procedures for Refurbished and Used Laboratory Refrigerators

1. Initial Visual Inspection
• Check exterior surfaces, hinges, and door gaskets for wear, corrosion, or damage
• Inspect power cords, plugs, and control panels for fraying or visible defects
• Verify that shelves, racks, and internal compartments are present and functional

2. Functional Testing
• Power on the refrigerator and verify that display screens, alarms, and controls function properly
• Test door latches and sealing mechanisms to ensure secure closure and insulation
• Run preliminary temperature cycles to observe startup behavior and cooling response

3. Temperature and Stability Testing
• Test internal temperature sensors and controllers using thermometers/probes
• Monitor temperature at multiple points within the chamber over an extended period
• Verify accuracy across user-defined setpoints (e.g., +4°C, +2°C to +8°C range)

4. Cooling System and Compressor Evaluation
• Test compressor startup, cycling, and operating noise levels
• Inspect condenser coils and fans for proper function and cleanliness
• Check refrigerant pressure (if applicable) and confirm there are no leaks or system inefficiencies

5. Electrical Safety and Compliance Checks
• Ensure all internal and external electrical components are properly grounded
• Perform insulation resistance and leakage current tests
6. Final Quality Assurance Checklist
• Run full operational tests over a 24-hour period
• Document temperature logs, control responsiveness, and system performance
• Complete a detailed service report

All refurbished laboratory refrigerators from American Instrument Exchange are backed by our rigorous testing standards and quality commitment. From vaccine storage to reagent preservation, you can count on consistent cold storage performance from day one.

Repair and Refurbishment Protocol for Used Laboratory Refrigerators
Cold Storage Performance from American Instrument Exchange

At American Instrument Exchange, every used laboratory refrigerator we offer is subjected to a comprehensive repair and refurbishment protocol. Whether it’s a general-purpose lab refrigerator, pharmaceutical-grade unit, or undercounter model, our goal is to restore each system to peak performance—ensuring consistent temperature control and reliable to laboratory storage standards.

Why Choose a Refurbished Laboratory Refrigerator from American Instrument Exchange?

• Fully tested for cold storage accuracy and operational safety
• Backed by a warranty
• Cost-effective alternative to new refrigeration equipment
• Sustainably refurbished to reduce environmental impact
• Serviced by expert technicians with decades of laboratory equipment experience

Step-by-Step Refurbishment Protocol

Every laboratory refrigerator from American Instrument Exchange follows a detailed, multi-stage process to ensure top-tier performance and reliability:

1. Initial Intake & Inspection

• Visual inspection for dents, corrosion, or structural damage
• Mechanical check of door hinges, gaskets, seals, and internal components
• Documentation of missing parts or areas requiring repair or replacement

2. Cleaning and Decontamination

• Internal and external cleaning using non-abrasive, lab-safe cleaners
• Decontamination/cleaning of all surfaces to remove biological or chemical residues
• Thorough cleaning of shelving, drawers, and removable interior parts

3. Mechanical and Electrical Repairs

• Replacement or repair of worn mechanical parts (door latches, seals, hinges, etc.)
• Inspection and restoration of control interfaces, thermostats, sensors, and displays
• Evaluation of wiring, relays, fuses, and power supply components for safety and integrity

4. Refrigeration System and Compressor Evaluation

• Testing of compressor function, condenser coils, and evaporators
• Inspection for refrigerant leaks and pressure performance (if applicable)
• Verification of proper airflow, fan operation, and defrost cycles

5. Temperature and Performance Testing

• Testing of temperature sensors and control boards
• Verification of temperature stability and uniformity throughout the chamber
• Testing of multiple setpoints (e.g., +2°C to +8°C) over extended operating periods

6. Safety and Compliance Checks

• Inspection of grounding and electrical insulation per lab safety standards
• Testing of alarm systems (if applicable) for temperature excursions or power failure

7. Final Quality Control and Documentation

• Multi-day operational test under real-world conditions
• Final cleaning, inspection, and performance validation
• Detailed service report with temperature logs, repair notes, and certification of refurbishment

Trust the Experts at American Instrument Exchange

With over 50 years of industry experience, American Instrument Exchange is a leading provider of high-quality refurbished laboratory equipment. Our proven laboratory refrigerator refurbishment protocol ensures consistent, accurate cold storage—so you can safeguard your samples, reagents, and research materials with confidence.

Warranty Information

All used equipment sold by American Instrument Exchange is refurbished/reconditioned, tested to meet specifications, cleaned, and comes with a 90-day warranty from the date of shipment unless otherwise specified. New products include a warranty from the manufacturer. Your warranty is only valid if you have paid your invoice. If your invoice is over 30 days old, warranty work will not be performed until your invoice is paid in full. American Instrument Exchange is not liable for any special or consequential damages that result from the use of, or the inability to use, the materials on this site or the performance of the products,

Exceptions include international sales and items that are agreed to be sold with a lesser warranty or items that are agreed to be sold “as is.”

Should there be visible shipping damage to packaging or concealed shipping damage to item(s) supplied, buyer must communicate such damage to the delivering entity or carrier upon receipt first and to American Instrument the same day item is accepted / signed for. Failure to do so voids warranty. Customer decision to involve / procure third party or OEM service other than American Instrument or AIE assigned vendors to resolve in-warranty instrument failure or defect without first placing a service call to American Instrument voids warranty.

Return & Cancellation Policy

American Instrument Exchange will authorize the return of and issue a full refund for any equipment that is not working as represented and could not be replaced or repaired to the customer’s satisfaction by AIE or a representative of AIE during the warranty period. Returns without prior authorization and an RMA number will not be accepted.

Customers are responsible for proper packaging of the equipment and all included accessories. American Instrument will pay for insurance and shipping costs. Non-inventory items bought specifically to fill customer orders may possibly be returned, but on a case by case basis.

Customers who cancel orders after refurbishing has begun or after delivery where there are no equipment performance issues may be subject to a Restocking/Cancellation Fee of 20% or more and responsible for shipping costs for both the delivery and return.

Ongoing and Extended Support Options

American Instrument Exchange is able to provide additional repair and support services outside the warranty terms for most products that sell.

For biosafety cabinets, clean benches, chemical fume hoods, and other clean air products our team at AIE Laboratory Services can provide certifications, repairs, decontaminations, and other services for customers throughout New England, and guidance and limited technical assistance for any customers in the US and Canada for new or refurbished biosafety cabinets purchased from American Instrument Exchange.

For all other products, the repair service team at American Instrument Exchange can provide both field and depot repair evaluations. We can easily schedule and coordinate the pick-up and transportation of your malfunctioning equipment. By offering hourly rates lower than most OEM service providers and eliminating travel time for technicians, we help reduce repair costs. Furthermore, our lab depot repair service minimizes or eliminates scheduling delays. Our experienced service technicians are qualified to restore your equipment to factory specifications.

Please contact our team at info@americaninstrument.com for more details.

FAQ

Does the equipment come with a warranty?

Yes, all equipment from American Instrument Exchange comes with a warranty.
Used/reconditioned/refurbished equipment is tested to make sure it operates to the manufacturer's specifications and comes with a 90-day warranty (unless otherwise noted). New equipment comes with a warranty from the manufacturer.

How do you test and recondition the equipment?

Testing requirements vary across all the equipment categories we sell. Temperature controlled units are tested with NIST traceable probes and data loggers. Gaskets, external housing, glass, handles, controls and control screens are all thoroughly inspected for integrity and functionality.
We test all equipment using the manufacturer's parameters and specifications to confirm that the unit operates properly.

How do products ship from American Instrument Exchange?

We can ship products both nationally and internationally using a well-established network of transporters. Smaller items will ship via UPS. Larger equipment will be palletized and shipped either LTL or air-ride, depending on the specific equipment and/or delivery requirements.

Return and order cancellation policy

American Instrument Exchange will accept the return of any product that is not working as represented and could not be replaced or repaired to the customer's satisfaction during the warranty period. Customers who cancel orders after refurbishing has begun will be subject to a cancellation and restocking fee of between 20% and 40%.

Are discounts available for educational or non-profit institutions, or for bulk purchases?

Yes – call or email us today with a list of equipment you're looking for and we can potentially put together a quote that includes a discount.

How does your price matching policy work?

We strive to keep our pricing competitive and reasonable. If you find comparable items for sale at a lower price from other vendors please send us a link and or quote for the item and we'll do our best to match or beat the price.

Can I see the equipment in person before committing to a purchase?

Customers are welcome to make an appointment to view equipment in our warehouse. Given our workload we may not be able to test or clean the equipment prior to your arrival if you have not committed to an order.

1023 Western Avenue is a working warehouse, not a showroom, and customers should dress appropriately and wear closed toe shoes.

Can I ship products that I purchased elsewhere to American Instrument for repair?

Yes – please see our repair services page for more information.