Mettler Toledo XPE105 Excellence Plus Semi-Micro Analytical Balance
Shipping
All products ship from our 30,000 sq. ft. Haverhill, MA warehouse
Shipping
All products ship from our 30,000 sq. ft. Haverhill, MA warehouse
The Mettler Toledo XPE105 Excellence Plus Semi-Micro Analytical Balance is a high-performance laboratory balance combining 120 g maximum capacity with 0.01 mg / 10 µg readability throughout its entire weighing range. Designed for pharmaceutical analysis, reference-standard preparation, quantitative chemistry, gravimetric analysis, formulation, quality control, and demanding research applications, the XPE105 provides ten times finer displayed resolution than a conventional 0.1 mg analytical balance.
Available used and refurbished from American Instrument Exchange, the XPE105 belongs to Mettler Toledo's newer Excellence Plus generation and incorporates advanced weighing and workflow technologies including proFACT Advanced automatic internal adjustment, SmartGrid, StaticDetect, MinWeigh, LevelGuide, StatusLight, a motorized glass draft shield, touchscreen operation, hands-free sensors, electronic data connectivity, and LabX compatibility.
Unlike a dual-range balance, the XPE105 is a single-range model. Its full 0.01 mg / 10 µg readability remains available throughout the complete 120 g weighing capacity, making it particularly useful when high resolution is required even with heavier tare vessels or samples approaching the upper end of the weighing range.
Each XPE105 is inspected, cleaned, calibrated, and tested for weighing performance before shipment and includes a 90-day warranty from American Instrument Exchange.
120 g maximum weighing capacity
0.01 mg / 10 µg readability
Single-range semi-micro analytical weighing
Typical repeatability of approximately 0.007 mg / 7 µg
Repeatability limit of approximately 0.03 mg at a 100 g load
Typical USP minimum sample weight of approximately 14 mg
Typical automated USP minimum weight of approximately 10 mg
Linearity deviation of ±0.1 mg
Approximately 2.5-second manufacturer-listed settling time
proFACT Advanced automatic internal adjustment
SmartGrid weighing pan
StaticDetect electrostatic-charge detection
MinWeigh minimum-weight monitoring
LevelGuide leveling assistance
StatusLight visual balance-status indicator
Motorized glass draft shield
SmartSens hands-free operation
73 × 78 mm weighing pan
Approximately 235 mm usable draft-shield height
Color touchscreen interface
USB, RS232, and Ethernet/LAN connectivity options
LabX compatible
Used, refurbished, calibrated, and tested by American Instrument Exchange
90-day warranty included
The Mettler Toledo XPE105 is best understood as a single-range semi-micro analytical balance.
A conventional analytical balance typically provides 0.1 mg / 100 µg readability. The XPE105 provides 0.01 mg / 10 µg readability, allowing it to resolve changes in mass ten times smaller.
This additional sensitivity makes the XPE105 particularly useful for laboratories working with smaller sample quantities, expensive compounds, pharmaceutical reference materials, potent substances, filters, residues, and other procedures where conventional analytical resolution may be insufficient.
Unlike some dual-range semi-microbalances, the XPE105 does not restrict its highest resolution to a smaller fine range. The full 10 µg readability remains available all the way through its 120 g maximum capacity.
That makes the XPE105 particularly flexible for laboratories that need semi-micro resolution while working with relatively heavy sample containers or tare vessels.
The Mettler Toledo XPE105 is well suited for pharmaceutical formulation, reference-standard preparation, quantitative chemical analysis, gravimetric analysis, sample preparation, filter weighing, residue determination, environmental testing, quality control, density determination, differential weighing, percentage weighing, and high-resolution research applications.
Pharmaceutical and biotechnology laboratories can use the XPE105 for active pharmaceutical ingredients, reference standards, formulation components, potent compounds, research samples, and other materials where reducing sample quantities may provide significant advantages.
Chemical and analytical laboratories can use the balance for standards preparation, quantitative chemistry, compound weighing, and gravimetric procedures. Environmental laboratories may use the XPE105 for filters, residues, particulate measurements, and other applications involving relatively small changes in mass.
The XPE105 is particularly well suited for pharmaceutical, biotechnology, chemical, environmental, analytical testing, contract research, academic, materials science, quality-control, and R&D laboratories.
It is especially useful when laboratories need greater sensitivity than a conventional analytical balance but do not require the substantially lower capacity and more demanding installation requirements of a true microbalance.
The 120 g capacity also provides considerable flexibility for sample containers. Because the XPE105 maintains 10 µg readability throughout its full range, laboratories do not have to carefully manage tare weight simply to remain inside a smaller high-resolution fine range.
The XPE105 provides 0.01 mg / 10 µg readability throughout its entire 120 g weighing capacity.
Mettler Toledo specifies typical repeatability of approximately 7 µg under reference conditions. Manufacturer technical documentation also specifies a repeatability limit of approximately 0.03 mg at a 100 g load.
Linearity deviation is specified at ±0.1 mg. Mettler Toledo's model-specific archived product documentation specifies an approximately 2.5-second settling time.
This combination gives the XPE105 considerably greater sensitivity than a conventional analytical balance while maintaining practical weighing speed for repetitive laboratory procedures.
One of the most important characteristics of the XPE105 is that it is a single-range balance.
Its 10 µg readability is not limited to a smaller fine range. The same resolution remains available from low sample weights through the full 120 g capacity.
This can provide an important practical advantage. With a dual-range balance, the combined weight of the sample and tare vessel may determine whether the balance remains within its highest-resolution range.
With the XPE105, laboratories can use heavier vessels while retaining the full 10 µg readability. This makes the model particularly attractive for applications where both semi-micro resolution and flexible working capacity are important.
Mettler Toledo specifies a typical USP minimum sample weight of approximately 14 mg for the XPE105 under reference conditions.
The manufacturer also specifies a typical automated USP minimum weight of approximately 10 mg under appropriate automated conditions.
These figures demonstrate the distinction between readability and quantitative minimum weight. Although the XPE105 displays mass in increments as small as 0.01 mg, a 0.01 mg sample is not an appropriate quantitative minimum sample simply because the balance can display it.
Minimum weight depends primarily on repeatability and the maximum relative measurement uncertainty permitted by the procedure.
For USP, GMP, GLP, or other controlled applications, laboratories should determine minimum weight based on the actual repeatability of the installed XPE105 under its operating conditions.
The XPE105 incorporates MinWeigh functionality, allowing established minimum-weight requirements to become part of the weighing workflow.
When an appropriate minimum weight has been determined, MinWeigh can warn operators when the net sample quantity falls below the defined threshold.
This provides an important safeguard in laboratories where technicians routinely work with relatively small quantities. Instead of relying on the operator to remember a minimum sample requirement for every procedure, the balance can provide an immediate visual indication that the measurement may not satisfy the defined uncertainty requirement.
At 10 µg readability, environmental conditions become considerably more important than they are with conventional precision or analytical balances.
The XPE105 incorporates a fully enclosed motorized glass draft shield to protect the SmartGrid weighing pan from routine laboratory airflow. The approximately 235 mm usable chamber height provides room for a variety of vessels and sample containers.
The balance should nevertheless be positioned away from HVAC outlets, frequently used doors, windows, fans, and other significant airflow sources.
Vibration is equally important. The XPE105 should be installed on a rigid, stable weighing table away from centrifuges, shakers, pumps, compressors, refrigerators, freezers, and other equipment capable of transmitting vibration.
Samples should also be allowed to thermally equilibrate whenever possible before critical weighing.
Electrostatic charge can become a significant source of error at semi-micro resolution.
Powders, filters, plastic containers, films, glass vessels, disposable laboratory products, and other materials can accumulate static electricity during handling. These electrostatic forces may influence the displayed weight without changing the actual mass of the sample.
The XPE105 incorporates StaticDetect, which helps identify electrostatic charge that may compromise weighing accuracy.
This allows the operator to recognize the problem rather than unknowingly recording a potentially biased result.
Where necessary, laboratories can combine StaticDetect with appropriate antistatic equipment, conductive sample containers, grounding techniques, or humidity management.
The XPE105 incorporates Mettler Toledo's SmartGrid weighing pan.
The grid-style design reduces the surface area exposed to moving air compared with a conventional solid weighing pan. This helps reduce turbulence within the draft shield and can improve stabilization after samples are introduced.
SmartGrid also allows spilled material to fall below the primary weighing surface, simplifying routine cleaning and inspection.
At 10 µg readability, seemingly small improvements in airflow management can have a meaningful effect on practical weighing stability.
The XPE105 incorporates proFACT Advanced automatic internal adjustment.
This system uses internal reference weights to perform automatic time- and temperature-controlled adjustment, helping maintain weighing performance as environmental conditions change.
Automatic internal adjustment is especially useful at semi-micro resolution, where relatively small temperature changes can influence balance sensitivity.
proFACT Advanced reduces the need for operators to manually initiate routine adjustment using external weights.
Independent external verification may still be required under USP, GMP, GLP, ISO, or internal quality procedures. American Instrument Exchange verifies operation of the internal adjustment system and externally evaluates weighing performance during refurbishment.
The XPE105 incorporates LevelGuide to help operators identify when the balance is no longer properly leveled.
Correct leveling is fundamental to accurate high-resolution weighing.
The XPE platform also incorporates StatusLight, providing a visual indication of balance status.
These systems are particularly useful in multi-user laboratories where the balance may be cleaned, repositioned, or operated by numerous technicians.
Instead of relying entirely on the operator to recognize unsuitable operating conditions, the balance provides additional visual guidance before measurements are recorded.
The XPE105 incorporates a motorized glass draft shield and SmartSens hands-free sensors.
Frequently used functions can be performed with reduced physical interaction with the instrument.
This can improve ergonomics during repetitive weighing while also reducing unnecessary vibration and airflow disturbances caused by touching the balance or manually moving draft-shield panels.
At semi-micro resolution, reducing physical interaction is more than a convenience. Even relatively small disturbances can increase stabilization time or contribute to fluctuating measurements.
The XPE105 uses a color touchscreen interface for access to weighing applications, balance settings, stored information, and system functions.
Integrated applications support procedures such as statistics, formulation, density determination, percentage weighing, piece counting, differential weighing, and other analytical workflows.
The XPE platform was designed for laboratories where weighing is often part of a larger controlled procedure rather than an isolated measurement.
Stored settings and guided workflows can help improve consistency between users and reduce repetitive manual configuration.
The XPE105 supports USB, RS232, and Ethernet/LAN connectivity, depending on system configuration.
This allows the balance to communicate with compatible computers, printers, barcode readers, laboratory peripherals, and data-management systems.
The XPE105 is also compatible with Mettler Toledo LabX software.
LabX can support electronic data capture, calculations, method management, result storage, user controls, traceability, and other laboratory workflow functions when appropriately configured.
For laboratories operating under regulated or documentation-intensive procedures, these capabilities can substantially reduce reliance on handwritten weighing records and manual transcription.
| Specification | Mettler Toledo XPE105 |
|---|---|
| Balance Type | Semi-Micro Analytical Balance |
| Weighing Architecture | Single Range |
| Maximum Capacity | 120 g |
| Readability | 0.01 mg / 10 µg |
| Typical Repeatability | Approx. 0.007 mg / 7 µg |
| Repeatability Limit at 100 g | Approx. 0.03 mg |
| Typical USP Minimum Weight | Approx. 14 mg |
| Typical Automated USP Minimum Weight | Approx. 10 mg |
| Linearity | ±0.1 mg |
| Settling Time | Approx. 2.5 seconds |
| Adjustment | Internal / proFACT Advanced |
| Weighing Pan | SmartGrid |
| Pan Dimensions | 73 × 78 mm |
| Draft Shield | Motorized glass |
| Usable Draft-Shield Height | Approx. 235 mm |
| Static Detection | StaticDetect |
| Minimum Weight Monitoring | MinWeigh |
| Level Assistance | LevelGuide |
| Status Indicator | StatusLight |
| Hands-Free Operation | SmartSens |
| Overall Dimensions | 263 mm W × 487 mm D × 322 mm H |
| Display | Color touchscreen |
| Connectivity | USB, RS232, Ethernet/LAN compatible |
| LabX Compatible | Yes |
| Legal for Trade | No, standard XPE105 |
| Warranty | 90 days from American Instrument Exchange |
A conventional analytical balance generally provides 0.1 mg / 100 µg readability.
The XPE105 provides 0.01 mg / 10 µg readability, giving it ten times finer displayed resolution.
This additional sensitivity can be valuable when laboratories work with small sample quantities, expensive compounds, potent substances, pharmaceutical reference standards, filters, residues, and procedures with tighter uncertainty requirements.
However, greater sensitivity also increases susceptibility to vibration, air movement, static electricity, temperature gradients, and operator technique.
A conventional analytical balance may therefore be the more practical choice when 0.1 mg resolution satisfies the method. The XPE105 is best suited for applications that genuinely benefit from semi-micro-level 10 µg resolution.
The XPE105 should not be confused with the XPE105DR dual-range model.
The XPE105 provides 0.01 mg / 10 µg readability throughout its full 120 g capacity.
The XPE105DR provides 0.01 mg readability within a 41 g fine range and 0.1 mg readability across its full 120 g range.
This makes the single-range XPE105 particularly advantageous when laboratories need 10 µg resolution while working with total loads exceeding 41 g.
The XPE105DR can be appropriate when semi-micro resolution is needed only for smaller loads and conventional analytical resolution is sufficient for larger samples.
The XPE105 and XS105 share an important core specification: both provide approximately 120 g capacity with 0.01 mg / 10 µg readability.
The primary difference is generation and platform capability.
The XS105 belongs to Mettler Toledo's earlier Excellence XS generation.
The XPE105 belongs to the newer Excellence Plus platform, adding technologies such as StaticDetect, MinWeigh, StatusLight, LevelGuide, SmartSens operation, enhanced electronic workflows, and more sophisticated laboratory data-management capabilities.
For laboratories primarily concerned with core weighing performance, a properly refurbished XS105 can remain an excellent semi-microbalance.
The XPE105 becomes especially attractive when users value newer workflow, environmental-monitoring, data-integrity, and operator-assistance technologies.
The XPE105 and XPE205 both provide 0.01 mg / 10 µg single-range readability.
Their primary difference is capacity.
The XPE105 provides 120 g maximum capacity, while the XPE205 increases capacity to approximately 220 g.
For laboratories whose samples and tare vessels remain comfortably below 120 g, the XPE105 provides the same displayed resolution without unnecessary additional capacity.
The XPE205 becomes preferable when heavier vessels, larger samples, or greater tare capacity are routinely required.
Single-range architecture can provide an important advantage for laboratories that consistently require high resolution.
With the XPE105, technicians do not have to monitor whether the total load remains inside a smaller fine range to preserve 10 µg readability.
The balance maintains its highest resolution throughout the entire 120 g capacity.
This can simplify method development, vessel selection, and routine sample handling.
For laboratories that regularly require semi-micro performance rather than using it only occasionally, this consistency can make the XPE105 more convenient than a dual-range alternative.
Every used Mettler Toledo XPE105 sold by American Instrument Exchange is inspected, cleaned, refurbished as necessary, calibrated, and tested before shipment.
Our technicians use appropriate calibration weights to evaluate critical weighing characteristics including accuracy, repeatability, linearity, corner-load performance, stability, and reduced span across appropriate portions of the weighing range.
The weighing system, proFACT Advanced automatic internal adjustment, SmartGrid pan, StaticDetect, MinWeigh, LevelGuide, StatusLight, motorized draft shield, SmartSens sensors, touchscreen, interfaces, and other installed functions are inspected and tested for proper operation.
The weighing chamber, SmartGrid pan, glass draft-shield panels, and accessible components are thoroughly cleaned. The balance then receives a final operational inspection before shipment.
Each refurbished XPE105 includes a 90-day warranty from American Instrument Exchange.
A semi-microbalance capable of resolving 10 µg changes requires careful transportation and installation.
American Instrument Exchange securely prepares the XPE105 for shipment to protect its weighing system, SmartGrid pan, motorized glass draft shield, touchscreen terminal, sensors, and electronic components.
Once received, the balance should be installed on a rigid, stable, vibration-resistant weighing table away from HVAC outlets, doors, direct sunlight, centrifuges, shakers, pumps, compressors, and other significant sources of airflow or vibration.
The balance should be properly leveled and allowed to acclimate to the laboratory environment before critical quantitative measurements begin.
For regulated or demanding applications, installation should be followed by appropriate calibration verification, repeatability testing, minimum-weight determination, or qualification according to the laboratory's quality procedures.
American Instrument Exchange maintains an extensive inventory of used and refurbished laboratory balances, including analytical balances, semi-micro balances, microbalances, and precision balances for applications ranging from routine sample preparation to high-resolution quantitative analysis.
Labs developing complete analytical or sample-preparation workflows can also source centrifuges, water baths, incubators, laboratory refrigerators, laboratory freezers, and other refurbished laboratory equipment from American Instrument Exchange.
The XPE105 has a maximum weighing capacity of 120 g.
The XPE105 provides 0.01 mg / 10 µg readability throughout its entire 120 g capacity.
The XPE105 is commonly categorized within Mettler Toledo's analytical-balance family, but its 10 µg readability places it in the semi-micro performance class. Describing it as a semi-micro analytical balance accurately communicates both its product family and weighing resolution.
No. The XPE105 is a single-range balance, maintaining 10 µg readability throughout its full 120 g capacity.
Mettler Toledo specifies typical repeatability of approximately 7 µg under reference conditions.
Mettler Toledo specifies a typical USP minimum sample weight of approximately 14 mg and a typical automated USP minimum weight of approximately 10 mg under appropriate reference conditions.
Mettler Toledo's model-specific archived XPE105 documentation specifies an approximately 2.5-second settling time.
Yes. The XPE105 incorporates proFACT Advanced, Mettler Toledo's automatic internal adjustment system.
StaticDetect helps identify electrostatic charge that may influence high-resolution weighing results. This can be particularly useful when weighing powders, filters, plastics, glassware, films, and other materials prone to static buildup.
MinWeigh allows an established minimum sample weight to be incorporated into the weighing workflow and can warn users when the net sample quantity falls below the defined threshold.
The XPE105 provides 10 µg readability throughout its full 120 g capacity. The XPE105DR provides 10 µg readability only within its 41 g fine range and 0.1 mg readability through its full 120 g range.
Both provide approximately 120 g capacity and 10 µg readability. The XPE105 is the newer Excellence Plus platform, adding technologies such as StaticDetect, MinWeigh, StatusLight, LevelGuide, SmartSens, and enhanced electronic workflow capabilities.
Yes. The XPE105 can be integrated with Mettler Toledo LabX software for electronic data capture, method management, calculations, result storage, traceability, and other laboratory workflow functions when appropriately configured.
A refurbished XPE105 provides laboratories with 120 g capacity, 10 µg single-range readability, proFACT Advanced, StaticDetect, MinWeigh, SmartGrid, a motorized draft shield, touchscreen operation, hands-free sensors, and advanced electronic workflow capabilities at a lower acquisition cost than comparable new semi-micro weighing systems. American Instrument Exchange tests, calibrates, cleans, and refurbishes each balance before shipment and provides a 90-day warranty.
Yes, all equipment from American Instrument Exchange comes with a warranty.
Used/reconditioned/refurbished equipment is tested to make sure it operates to the manufacturer's specifications and comes with a 90-day warranty (unless otherwise noted). New equipment comes with a warranty from the manufacturer.
Testing requirements vary across all the equipment categories we sell. Temperature controlled units are tested with NIST traceable probes and data loggers. Gaskets, external housing, glass, handles, controls and control screens are all thoroughly inspected for integrity and functionality.
We test all equipment using the manufacturer's parameters and specifications to confirm that the unit operates properly.
We can ship products both nationally and internationally using a well-established network of transporters. Smaller items will ship via UPS. Larger equipment will be palletized and shipped either LTL or air-ride, depending on the specific equipment and/or delivery requirements.
American Instrument Exchange will accept the return of any product that is not working as represented and could not be replaced or repaired to the customer's satisfaction during the warranty period. Customers who cancel orders after refurbishing has begun will be subject to a cancellation and restocking fee of between 20% and 40%.
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