Thermo Scientific Heratherm IMH400-S Incubator

Brand : Thermo

Product Code : SKU 3142K INC

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Thermo Scientific Heratherm IMH400-S Microbiological Incubator

High-throughput microbiology, pharmaceutical, biotechnology, and clinical laboratories require dependable incubation conditions while minimizing the risk of sample contamination. Whether culturing microorganisms, performing quality control testing, validating pharmaceutical products, or supporting research workflows, laboratories benefit from incubators that combine precise temperature control with advanced contamination management and programmable operation. The Thermo Scientific Heratherm IMH400-S Microbiological Incubator is designed for these demanding applications, offering a 13.5 cubic foot (381 L) chamber, mechanical convection, programmable microprocessor controls, and a unique 140°C decontamination cycle that significantly reduces microbial contamination within the chamber.

Unlike a general-purpose laboratory incubator, the Heratherm IMH400-S incorporates features specifically intended to improve laboratory productivity and sample protection. Adjustable airflow, programmable operating schedules, integrated safety alarms, and contamination reduction technology allow laboratories to maintain consistent incubation conditions while reducing maintenance requirements between studies. Purchasing a refurbished Thermo Scientific Heratherm IMH400-S from American Instrument Exchange provides laboratories with a premium large-capacity incubator at a substantial savings compared to purchasing a new system.

Thermo Scientific Heratherm IMH400-S Key Features

13.5 cu. ft. (381 L) chamber capacity
Temperature range: Ambient +5°C to 105°C
140°C chamber decontamination cycle
Mechanical convection with adjustable fan speed
Temperature stability of ±0.2°C at 37°C
Programmable microprocessor controller
Weekly timer, real-time clock, and multi-step programming
Lockable door for sample security
Door-open, overtemperature, and undertemperature alarms
Stainless steel chamber interior
Internal glass door for sample viewing
Access port for probes and monitoring devices
120V electrical operation
90-day warranty from American Instrument Exchange

Designed for High-Throughput Microbiology Laboratories

The Thermo Scientific Heratherm IMH400-S is engineered to provide dependable incubation performance for laboratories processing large sample volumes. Its spacious 381-liter chamber accommodates multiple shelves of culture media, microbiological samples, pharmaceutical products, and quality control materials while maintaining excellent temperature uniformity through mechanical convection. The adjustable fan allows laboratories to tailor airflow to different applications, balancing rapid temperature recovery with gentle air movement for more sensitive samples.

One of the defining features of the IMH400-S is its integrated 140°C decontamination cycle. This certified six-hour cycle dramatically reduces microbial contamination inside the chamber without requiring removal and autoclaving of internal shelves and fittings, reducing downtime while helping laboratories maintain cleaner incubation environments. Combined with programmable operating schedules, sample security features, and comprehensive alarm protection, the IMH400-S supports laboratories where reproducibility, contamination control, and operational efficiency are essential.

Common Applications

The Thermo Scientific Heratherm IMH400-S is commonly used for:

Microbiological culturing
Clinical microbiology
Pharmaceutical quality control
Sterility testing
Environmental microbiology
Food and beverage microbiology
Water quality testing
Cell culture support applications
Biological research
General laboratory incubation
Method validation
Routine quality assurance testing

The IMH400-S is frequently used alongside biosafety cabinets for aseptic sample preparation, laboratory refrigerators for media and reagent storage, laboratory freezers for long-term sample preservation, centrifuges for sample processing, and autoclaves for sterilization of laboratory materials.

Ideal Laboratory Environments

The Thermo Scientific Heratherm IMH400-S is an excellent choice for pharmaceutical manufacturers, biotechnology companies, clinical laboratories, microbiology laboratories, food and beverage testing facilities, environmental testing organizations, public health laboratories, contract testing laboratories, universities, and industrial quality assurance departments. Its large chamber capacity, contamination control features, and programmable operation make it especially valuable for laboratories processing high sample volumes while maintaining rigorous quality standards.

Why Choose the Thermo Scientific Heratherm IMH400-S?

The Thermo Scientific Heratherm IMH400-S combines high-capacity incubation, precise temperature control, advanced contamination management, and programmable laboratory automation in a single dependable platform. Its unique 140°C decontamination cycle, adjustable airflow, integrated safety features, and spacious chamber help laboratories improve productivity while maintaining consistent incubation conditions.

Whether supporting microbiological research, pharmaceutical quality assurance, clinical diagnostics, or industrial testing, the Heratherm IMH400-S delivers the reliability, contamination control, and operational flexibility required by today's modern laboratories.

Performance and Temperature Uniformity

The Thermo Scientific Heratherm IMH400-S Microbiological Incubator is designed to provide dependable temperature control for routine and high-throughput laboratory workflows where consistent incubation conditions are essential for reliable results. Its mechanical convection system continuously circulates conditioned air throughout the chamber, promoting excellent temperature uniformity across all shelving levels while providing rapid temperature recovery following routine door openings.

A programmable microprocessor controller allows users to establish precise operating temperatures and create customized incubation programs for different laboratory protocols. Weekly scheduling, real-time clock functionality, and multi-step programming simplify routine laboratory operations by automating incubation cycles and reducing the need for manual intervention. Whether processing microbiological cultures, quality control samples, or research materials, laboratories benefit from stable environmental conditions that improve experimental reproducibility.

One of the Heratherm IMH400-S's most significant advantages is its integrated 140°C chamber decontamination cycle. Unlike conventional cleaning procedures that require removal of internal components or chemical disinfectants, the chamber can be thermally decontaminated using a validated high-temperature cycle that dramatically reduces microbial contamination. This feature minimizes downtime between studies while helping laboratories maintain cleaner incubation environments and reducing the risk of cross-contamination between successive research or quality control projects.

Additional features including adjustable fan speed, comprehensive alarm monitoring, and a lockable door further enhance operational reliability. Door-open, overtemperature, and undertemperature alarms provide added sample protection, while the internal glass door allows researchers to inspect cultures without exposing the chamber to unnecessary temperature fluctuations.

Typical Samples and Laboratory Applications

The Thermo Scientific Heratherm IMH400-S supports a wide variety of microbiological, pharmaceutical, clinical, and industrial laboratory applications. Typical samples include bacterial cultures, yeast, fungi, environmental microorganisms, culture media, pharmaceutical products, sterility test samples, water quality samples, food products, beverages, biological specimens, quality control materials, laboratory reference standards, and research cultures.

Common laboratory applications include microbiological incubation, pharmaceutical quality control, sterility testing, clinical microbiology, environmental monitoring, food and beverage testing, water quality analysis, biological research, method validation, quality assurance, routine laboratory incubation, and educational laboratory instruction. Its large chamber capacity makes the incubator especially valuable for laboratories processing multiple projects simultaneously while maintaining consistent incubation conditions.

Thermo Scientific Heratherm IMH400-S Specifications

Specification	Details
Manufacturer	Thermo Scientific
Model	Heratherm IMH400-S
Equipment Type	Microbiological Incubator
Chamber Capacity	13.5 cu. ft. (381 L)
Exterior Dimensions	Approximately 34.5" W × 31.5" D × 76.5" H
Interior Dimensions	Approximately 25.8" W × 22.8" D × 40.0" H
Temperature Range	Ambient +5°C to 105°C
Temperature Stability	±0.2°C at 37°C
Air Circulation	Mechanical Convection with Adjustable Fan Speed
Chamber Material	Stainless Steel
Controller	Programmable Microprocessor
Decontamination	140°C Thermal Decontamination Cycle
Alarms	Door Open, Overtemperature, Undertemperature
Interior Door	Tempered Glass
Access Port	Yes
Electrical Requirements	120V, 60 Hz

Specifications are compiled from manufacturer literature and American Instrument Exchange product information. Specifications may vary depending on production year and installed options. Please verify chamber dimensions, electrical requirements, temperature range, shelf configuration, and included accessories prior to purchase.

Frequently Asked Questions

What is the Heratherm IMH400-S designed for?

The Heratherm IMH400-S is a large-capacity microbiological incubator designed for laboratories performing microbiological culturing, pharmaceutical quality control, sterility testing, environmental microbiology, food safety testing, and other applications requiring precise and reliable temperature control.

What is the benefit of the 140°C decontamination cycle?

The integrated thermal decontamination cycle heats the chamber to 140°C for a validated cleaning cycle that significantly reduces microbial contamination. This helps minimize the risk of cross-contamination between studies while reducing the time required for routine chamber maintenance.

Why does the incubator use mechanical convection?

Mechanical convection continuously circulates air throughout the chamber, improving temperature uniformity and providing faster recovery after the door is opened. This makes the incubator well suited for laboratories with frequent sample access or high daily throughput.

Can the IMH400-S be programmed for different incubation protocols?

Yes. The programmable microprocessor controller supports real-time operation, weekly scheduling, and multi-step temperature programming, allowing laboratories to automate routine incubation workflows and improve consistency between experiments.

Which laboratories commonly use the Heratherm IMH400-S?

The IMH400-S is widely used in pharmaceutical companies, biotechnology laboratories, hospitals, clinical microbiology laboratories, food and beverage testing facilities, environmental laboratories, public health organizations, contract testing laboratories, universities, and industrial quality assurance departments.

Why purchase a refurbished Thermo Scientific Heratherm IMH400-S from American Instrument Exchange?

A refurbished Thermo Scientific Heratherm IMH400-S Microbiological Incubator from American Instrument Exchange provides laboratories with premium incubation performance at a substantial savings compared to purchasing a new system. Featuring a 13.5 cubic foot chamber, mechanical convection, a 140°C thermal decontamination cycle, programmable microprocessor controls, and excellent temperature stability, the IMH400-S is an outstanding choice for microbiology, pharmaceutical quality assurance, clinical diagnostics, environmental testing, and food safety laboratories. Every unit is thoroughly inspected and tested prior to shipment and includes a 90-day warranty from American Instrument Exchange.

Testing Procedures for Used and Refurbished Laboratory Incubators
Ensure Quality and Stability Before Use

Used and refurbished laboratory incubators from American Instrument Exchange are thoroughly tested to ensure optimal performance and temperature stability with laboratory safety standards. Each unit undergoes a detailed inspection and functionality assessment to meet the needs of research, clinical, and industrial labs.

Why Testing Used Laboratory Incubators Is Essential

Before a laboratory incubator is reintroduced into any work environment, it must be tested for:
• Temperature uniformity and accuracy
• Airflow and humidity control (if applicable)
• Door seal integrity and insulation effectiveness
• Electrical and safety system compliance

Comprehensive testing reduces the risk of culture loss, contamination, and equipment failure—especially critical in applications involving cell culture, microbiology, pharmaceutical research, and diagnostics.

Our multi-point testing protocol for used and refurbished incubators ensures reliability, safety, and performance across all models and brands.

Key Testing Procedures for Refurbished and Used Laboratory Incubators

1. Initial Visual Inspection
• Check for cosmetic damage, corrosion, and wear to exterior surfaces, door hinges, and gasket seals
• Inspect power cord, wiring, and display panel for any defects or signs of tampering
• Confirm that shelves, chamber components, and internal fixtures are present and undamaged

2. Functional Testing
• Power on the incubator and verify all display indicators and alarms function correctly
• Test door latch and seal mechanisms for proper closure and insulation
• Run basic temperature cycles to ensure the unit maintains stability over time

3. Temperature Accuracy and Uniformity Tests
• Test internal sensors and controllers using temperature probes
• Measure temperature consistency at multiple chamber locations over several hours
• Confirm that programmable temperature settings respond accurately

4. Airflow and Humidity Control (if applicable)
• Test internal fan operation and airflow distribution
• For humidified incubators, inspect and test humidity reservoirs, sensors, and control systems
• Check for condensation buildup and confirm environmental stability

5. Electrical Safety and Compliance Checks
• Ensure all electrical components are properly grounded
• Perform insulation resistance and leakage current tests
• Verify compliance with current electrical safety standards for laboratory equipment

6. Final Quality Assurance Checklist
• Perform full cycle testing at various temperature setpoints
• Document performance benchmarks and results

All refurbished incubators from American Instrument Exchange are backed by our commitment to quality and precision. With our strict testing procedures, you can rely on your incubator to deliver dependable results from day one.

Repair and Refurbishment Protocol for Used Laboratory Incubators
Performance and Quality from American Instrument Exchange

At American Instrument Exchange, every used laboratory incubator we sell goes through a repair and refurbishment protocol. Whether it’s a standard, CO₂, or refrigerated incubator, our goal is to restore each unit to laboratory-level performance—ensuring temperature accuracy, environmental stability, and long-term reliability in your lab.

Why Choose a Refurbished Laboratory Incubator from American Instrument Exchange?

• Fully tested for performance and safety
• Backed by a warranty
• Cost-effective alternative to new equipment
• Environmentally sustainable through reuse and restoration
• Refurbished by expert technicians with decades of lab equipment experience

Step-by-Step Refurbishment Protocol

Every incubator at American Instrument Exchange follows this comprehensive, multi-stage process:

1. Initial Intake & Inspection
• Visual inspection for cosmetic wear, corrosion, dents, or broken components
• Mechanical assessment of door hinges, gaskets, seals, and chamber components
• Document any missing parts or issues requiring repair or replacement

2. Cleaning and Decontamination
• Thorough internal and external cleaning using non-abrasive solutions
• Decontamination/cleaning of surfaces to remove biological, chemical, or particulate residue
• Cleaning of removable parts (e.g., shelves, trays, etc.)

3. Mechanical and Electrical Repair
• Repair or replacement of worn mechanical components such as door latches, fans, hinges, and seals
• Evaluation and repair of control panels, switches, thermostats, and displays
• Inspection and testing of wiring, fuses, relays, and power supplies

4. Environmental Control System Assessment
• For CO₂ incubators: CO₂ sensors, regulators, and gas delivery systems are tested
• For refrigerated incubators: compressors, condensers, and cooling systems are evaluated for performance and leaks
• Fan motors and airflow systems are tested to ensure uniform environmental conditions

5. Temperature and Sensor Testing
• All temperature sensors and controllers are tested using thermometers/probes
• Uniformity and accuracy tested at multiple chamber locations
• For humidified or CO₂ incubators, humidity and CO₂ stability are verified

6. Safety System Testing
• Test of over-temperature protection systems and alarms
• Evaluation of door sensors, safety interlocks, and power failure recovery

7. Final Quality Control and Documentation
• Full performance test run over 24 hours
• Validation of setpoints for temperature, CO₂ (if applicable), and humidity (if applicable)
• Final inspection and cleaning before packaging
• Complete service report

Trust the Experts at American Instrument Exchange

With over 50 years in the lab equipment industry, American Instrument Exchange is a trusted source for high-quality refurbished laboratory incubators. Our proven refurbishment protocol ensures every unit is reliable, accurate, and ready to meet the demands of your lab from day one.

Warranty Information

All used equipment sold by American Instrument Exchange is refurbished/reconditioned, tested to meet specifications, cleaned, and comes with a 90-day warranty from the date of shipment unless otherwise specified. New products include a warranty from the manufacturer. Your warranty is only valid if you have paid your invoice. If your invoice is over 30 days old, warranty work will not be performed until your invoice is paid in full. American Instrument Exchange is not liable for any special or consequential damages that result from the use of, or the inability to use, the materials on this site or the performance of the products,

Exceptions include international sales and items that are agreed to be sold with a lesser warranty or items that are agreed to be sold “as is.”

Should there be visible shipping damage to packaging or concealed shipping damage to item(s) supplied, buyer must communicate such damage to the delivering entity or carrier upon receipt first and to American Instrument the same day item is accepted / signed for. Failure to do so voids warranty. Customer decision to involve / procure third party or OEM service other than American Instrument or AIE assigned vendors to resolve in-warranty instrument failure or defect without first placing a service call to American Instrument voids warranty.

Return & Cancellation Policy

American Instrument Exchange will authorize the return of and issue a full refund for any equipment that is not working as represented and could not be replaced or repaired to the customer’s satisfaction by AIE or a representative of AIE during the warranty period. Returns without prior authorization and an RMA number will not be accepted.

Customers are responsible for proper packaging of the equipment and all included accessories. American Instrument will pay for insurance and shipping costs. Non-inventory items bought specifically to fill customer orders may possibly be returned, but on a case by case basis.

Customers who cancel orders after refurbishing has begun or after delivery where there are no equipment performance issues may be subject to a Restocking/Cancellation Fee of 20% or more and responsible for shipping costs for both the delivery and return.

Ongoing and Extended Support Options

American Instrument Exchange is able to provide additional repair and support services outside the warranty terms for most products that sell.

For biosafety cabinets, clean benches, chemical fume hoods, and other clean air products our team at AIE Laboratory Services can provide certifications, repairs, decontaminations, and other services for customers throughout New England, and guidance and limited technical assistance for any customers in the US and Canada for new or refurbished biosafety cabinets purchased from American Instrument Exchange.

For all other products, the repair service team at American Instrument Exchange can provide both field and depot repair evaluations. We can easily schedule and coordinate the pick-up and transportation of your malfunctioning equipment. By offering hourly rates lower than most OEM service providers and eliminating travel time for technicians, we help reduce repair costs. Furthermore, our lab depot repair service minimizes or eliminates scheduling delays. Our experienced service technicians are qualified to restore your equipment to factory specifications.

Please contact our team at info@americaninstrument.com for more details.

FAQ

Does the equipment come with a warranty?

Yes, all equipment from American Instrument Exchange comes with a warranty.
Used/reconditioned/refurbished equipment is tested to make sure it operates to the manufacturer's specifications and comes with a 90-day warranty (unless otherwise noted). New equipment comes with a warranty from the manufacturer.

How do you test and recondition the equipment?

Testing requirements vary across all the equipment categories we sell. Temperature controlled units are tested with NIST traceable probes and data loggers. Gaskets, external housing, glass, handles, controls and control screens are all thoroughly inspected for integrity and functionality.
We test all equipment using the manufacturer's parameters and specifications to confirm that the unit operates properly.

How do products ship from American Instrument Exchange?

We can ship products both nationally and internationally using a well-established network of transporters. Smaller items will ship via UPS. Larger equipment will be palletized and shipped either LTL or air-ride, depending on the specific equipment and/or delivery requirements.

Return and order cancellation policy

American Instrument Exchange will accept the return of any product that is not working as represented and could not be replaced or repaired to the customer's satisfaction during the warranty period. Customers who cancel orders after refurbishing has begun will be subject to a cancellation and restocking fee of between 20% and 40%.

Are discounts available for educational or non-profit institutions, or for bulk purchases?

Yes – call or email us today with a list of equipment you're looking for and we can potentially put together a quote that includes a discount.

How does your price matching policy work?

We strive to keep our pricing competitive and reasonable. If you find comparable items for sale at a lower price from other vendors please send us a link and or quote for the item and we'll do our best to match or beat the price.

Can I see the equipment in person before committing to a purchase?

Customers are welcome to make an appointment to view equipment in our warehouse. Given our workload we may not be able to test or clean the equipment prior to your arrival if you have not committed to an order.

1023 Western Avenue is a working warehouse, not a showroom, and customers should dress appropriately and wear closed toe shoes.

Can I ship products that I purchased elsewhere to American Instrument for repair?

Yes – please see our repair services page for more information.