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Thermo Scientific CryoExtra™ 20 Liquid Nitrogen Storage System
As research programs mature and biological collections expand, laboratories need more than dependable cryogenic temperatures—they need an efficient way to organize, access, and protect thousands of valuable specimens. The Thermo Scientific CryoExtra™ 20 Liquid Nitrogen Storage System was developed to meet those demands, combining high-capacity liquid nitrogen storage with flexible inventory configurations that support modern biobanking, cell therapy manufacturing, and long-term research preservation.
Designed for laboratories that manage large cryogenic inventories, the CryoExtra 20 provides exceptional storage density while maintaining temperatures suitable for long-term preservation of sensitive biological materials. Whether storing stem cells, PBMCs, embryos, cord blood, or valuable research collections, the CryoExtra 20 helps laboratories maximize storage capacity while simplifying inventory organization and retrieval.
A complete cryopreservation workflow often begins with sample preparation inside biosafety cabinets, continues through controlled freezing using a Thermo Scientific CryoMed Controlled-Rate Freezer, and concludes with long-term preservation inside a cryogenic storage system such as the CryoExtra 20. Many laboratories also maintain ultralow freezers for applications that require mechanical refrigeration rather than liquid nitrogen storage.
Thermo Scientific CryoExtra™ 20 Key Features
High-capacity liquid nitrogen storage system
Vapor-phase or liquid-phase storage capability
Vacuum-insulated aluminum construction
High-density rack and box storage configurations
Lockable insulated lid
Compatible with standard cryobox inventory systems
Designed for long static hold times
Durable powder-coated exterior
Refurbished and performance tested by American Instrument Exchange
90-day warranty included
Thermo Scientific CryoExtra™ 20 Overview
Unlike mechanical laboratory freezers, the CryoExtra 20 relies on liquid nitrogen to maintain cryogenic temperatures for long-term preservation of biological materials. Its vacuum-insulated vessel minimizes heat transfer, reducing liquid nitrogen consumption while maintaining stable storage temperatures for extended periods.
The CryoExtra platform was designed around inventory flexibility. Multiple rack configurations allow laboratories to organize cryoboxes by project, department, study, or investigator, making it easier to locate samples while reducing unnecessary handling of neighboring specimens. This combination of high storage density and organized inventory management makes the CryoExtra 20 well suited for laboratories managing growing biological collections.
Common Applications
The Thermo Scientific CryoExtra 20 is commonly used for:
Stem cell banking
Cell line repositories
PBMC storage
CAR-T therapy manufacturing
Cord blood banking
Embryo and oocyte preservation
Sperm banking
Tissue repositories
Biopharmaceutical sample archives
Clinical trial specimen storage
Long-term research collections
University biobanks
Rather than functioning as a freezing device, the CryoExtra 20 provides secure long-term storage after samples have completed controlled-rate freezing.
Ideal Laboratory Types
The CryoExtra 20 is particularly well suited for:
Biotechnology companies
Pharmaceutical manufacturers
Cell therapy laboratories
Academic research institutions
IVF laboratories
Clinical research organizations
Biobanks
Public health laboratories
Government research facilities
Its high storage density makes it especially attractive for laboratories that anticipate continued growth of their biological collections.
Why High-Density Cryogenic Storage?
As sample inventories expand, storage efficiency becomes increasingly important. High-density cryogenic systems reduce floor space requirements while allowing laboratories to organize thousands of specimens within a single storage vessel.
The CryoExtra 20 supports standardized cryobox storage systems, making inventory tracking easier and improving sample accessibility without sacrificing cryogenic performance. Laboratories often combine multiple CryoExtra systems to organize collections by research program, sample type, or regulatory requirements while maintaining consistent cryogenic storage conditions.
Typical Stored Materials
The CryoExtra 20 is commonly used to preserve stem cells, cell lines, PBMCs, CAR-T products, cord blood, bone marrow, embryos, oocytes, sperm, DNA repositories, tissue specimens, biobank collections, and more.
Manual filling or facility-specific refill procedures
Operating Costs & Liquid Nitrogen Management
Because the CryoExtra 20 utilizes liquid nitrogen rather than mechanical refrigeration, operating costs are driven primarily by liquid nitrogen consumption, evaporation rates, refill schedules, and laboratory usage patterns. The vacuum-insulated vessel is designed to maximize static hold time, helping reduce nitrogen consumption while maintaining dependable long-term cryogenic storage.
Specifications compiled from Thermo Scientific manufacturer literature and American Instrument Exchange product information.
Refurbishment & Testing Process
Every Thermo Scientific CryoExtra 20 received by American Instrument Exchange undergoes a comprehensive inspection before shipment. Our technicians inspect the vessel, lid assembly, neck tube, inventory canisters, and associated hardware while evaluating overall condition and preparing the system for dependable laboratory operation.
The CryoExtra 20 ships by freight from American Instrument Exchange. Before installation, laboratories should verify adequate floor space, ventilation, and access to a reliable liquid nitrogen supply. Because liquid nitrogen can displace oxygen in confined areas, installations should follow institutional safety procedures regarding ventilation, oxygen monitoring, and personal protective equipment.
Frequently Asked Questions
How does the CryoExtra 20 differ from a CryoPlus storage system?
The CryoExtra series emphasizes high-density cryogenic storage and flexible inventory organization. Depending on the specific model configuration, CryoPlus systems often incorporate automated liquid nitrogen level management, while CryoExtra systems are frequently selected for their storage efficiency and long static hold times.
Can the CryoExtra 20 store samples in vapor phase?
Yes. The CryoExtra 20 supports both vapor-phase and liquid-phase storage, allowing laboratories to choose the storage method that best aligns with their research protocols and regulatory requirements.
Is the CryoExtra 20 used to freeze samples?
No. Samples are typically frozen first using a controlled-rate freezer before being transferred into the CryoExtra 20 for long-term cryogenic preservation.
How is the CryoExtra 20 tested before shipment?
Every refurbished Thermo Scientific CryoExtra 20 is inspected by American Instrument Exchange technicians to verify vessel integrity, inventory hardware, lid operation, and overall condition before shipment.
CLICK HERE to see the CryoExtra 20 on our YouTube channel
Testing Procedures for Used and Refurbished Laboratory Equipment
Ensure Accuracy, Safety, and Dependable Performance Across Applications
At American Instrument Exchange, all used and refurbished laboratory equipment undergoes a rigorous, multi-point testing protocol to ensure optimal performance, operational safety, and long-term reliability. Whether the equipment is destined for research, diagnostics, quality control, or production environments, our thorough inspection and testing process is designed to meet the highest standards of laboratory excellence.
Why Testing Used Lab Equipment Is Essential
Before any refurbished laboratory equipment is returned to service, it must be carefully tested to verify:
• Functional integrity and operational performance
• Setpoint accuracy and repeatability (where applicable)
• User interface responsiveness and control features
Proper testing reduces the risk of equipment failure, measurement inaccuracies, or user hazards—helping to ensure consistent results in clinical, academic, biotech, and industrial labs.
Our standardized lab equipment testing procedures are tailored to each equipment type, ensuring every unit meets manufacturer specifications and industry benchmarks.
Key Testing Procedures for Refurbished and Used Laboratory Equipment
1. Initial Visual Inspection
• Examine equipment housing for signs of wear, corrosion, or damage
• Check ports, power cords, and exterior components for tampering or deterioration
• Verify that internal and external parts (racks, shelves, connectors, accessories) are present and undamaged
2. Functional Startup and Operational Testing
• Power on the equipment and verify startup diagnostics
• Confirm functionality of displays, buttons, switches, and control panels
• Run basic functions to confirm proper response and behavior under standard operating conditions
3. Testing and Performance Verification
• Test internal sensors or control systems using industry-standard tools
• Perform operational tests to validate accuracy and consistency
• Verify key performance specifications such as temperature control, timing, speed, or measurement outputs, depending on equipment type
4. Mechanical and Electrical System Testing
• Evaluate motors, pumps, fans, or other moving parts for smooth operation
• Inspect and test wiring, relays, fuses, and circuit boards for safety and reliability
• Test power delivery and grounding compliance
5. Safety and Compliance Checks
• Ensure equipment is grounded and insulated to meet laboratory safety standards
• Test alarms, interlocks, emergency stops, or safety shutdown systems if applicable
6. Final Quality Assurance and Documentation
• Perform extended runtime testing
• Document operational logs, testing results, and any repairs or adjustments made
• Complete a final inspection, thorough cleaning, and packaging for delivery
Trusted Quality from American Instrument Exchange
With over 50 years of experience in laboratory equipment refurbishment, American Instrument Exchange is committed to delivering certified, lab-ready instruments backed by expert testing. Our testing protocols ensure that each piece of equipment—regardless of type—is safe, accurate, and dependable from day one.
Whether you're equipping a startup lab or expanding a high-throughput facility, you can count on our refurbished laboratory equipment to perform with precision and reliability.
Refurbishment Protocol for Used Laboratory Equipment from American Instrument Exchange
At American Instrument Exchange, every piece of used laboratory equipment we offer undergoes a multi-step refurbishment process. Whether it's an analytical balance, centrifuge, freezer, oven, or any other essential lab instrument, our goal is to restore each unit to peak performance—ensuring accuracy, safety, and long-term reliability in scientific, clinical, industrial, and academic environments.
Why Choose Refurbished Lab Equipment from American Instrument Exchange?
• Thoroughly tested for performance, precision, and safety
• Backed by a warranty
• A cost-effective alternative to new equipment
• Environmentally sustainable through equipment reuse and waste reduction
• Serviced by expert technicians with decades of laboratory equipment experience
Step-by-Step Refurbishment Protocol
Every instrument and system refurbished at American Instrument Exchange follows a detailed, industry-aligned process:
1. Initial Intake & Inspection
• Complete visual and structural inspection for cosmetic damage, wear, or corrosion
• Mechanical assessment of hinges, seals, fasteners, motors, and moving parts
• Missing components and damaged items are documented for repair or replacement
2. Cleaning and Decontamination
• Full internal and external cleaning using non-abrasive, lab-safe solutions
• Removal of biological, chemical, or particulate contamination
• Disassembly and cleaning of removable parts such as trays, shelves, and filters
3. Mechanical and Electrical Repair
• Replacement or repair of worn or broken mechanical parts
• Evaluation and servicing of control panels, sensors, switches, and displays
• Testing and repair of electrical wiring, fuses, circuit boards, and power supplies
4. Functional System Testing
• Assessment of all major functions specific to the equipment type (e.g., speed, temperature, force, weight, timing)
• Operation of control interfaces, programming menus, and digital displays
• Verification of stabilization time, responsiveness, and user input reliability
5. Testing and Performance Verification
• Testing of internal sensors, controllers, and measurement systems using certified tools
• Multi-point testing to ensure repeatability, accuracy, and performance consistency
• Confirmation of user-defined setpoints, timing sequences, or programmable cycles
6. Safety and Compliance Checks
• Testing of safety interlocks, alarms, and over-limit protection systems (as applicable)
• Electrical safety inspections, including grounding and insulation verification
7. Final Quality Assurance and Documentation
• Full operational testing under simulated lab conditions
• Completion of performance benchmarks, testing results, and repair logs
• Final cleaning and visual inspection
Trust the Experts at American Instrument Exchange
With over 50 years of experience in the laboratory equipment industry, American Instrument Exchange is a trusted leader in high-quality refurbished lab instruments. Our refurbishment protocols ensure that every piece of equipment we sell is lab-ready—offering the precision, performance, and durability your team can count on.
Whether you’re outfitting a new lab or expanding an existing operation, choose American Instrument Exchange for tested, warrantied, and cost-effective laboratory equipment.
Warranty Information
All used equipment sold by American Instrument Exchange is refurbished/reconditioned, tested to meet specifications, cleaned, and comes with a 90-day warranty from the date of shipment unless otherwise specified. New products include a warranty from the manufacturer. Your warranty is only valid if you have paid your invoice. If your invoice is over 30 days old, warranty work will not be performed until your invoice is paid in full. American Instrument Exchange is not liable for any special or consequential damages that result from the use of, or the inability to use, the materials on this site or the performance of the products,
Exceptions include international sales and items that are agreed to be sold with a lesser warranty or items that are agreed to be sold “as is.”
Should there be visible shipping damage to packaging or concealed shipping damage to item(s) supplied, buyer must communicate such damage to the delivering entity or carrier upon receipt first and to American Instrument the same day item is accepted / signed for. Failure to do so voids warranty. Customer decision to involve / procure third party or OEM service other than American Instrument or AIE assigned vendors to resolve in-warranty instrument failure or defect without first placing a service call to American Instrument voids warranty.
Return & Cancellation Policy
American Instrument Exchange will authorize the return of and issue a full refund for any equipment that is not working as represented and could not be replaced or repaired to the customer’s satisfaction by AIE or a representative of AIE during the warranty period. Returns without prior authorization and an RMA number will not be accepted.
Customers are responsible for proper packaging of the equipment and all included accessories. American Instrument will pay for insurance and shipping costs. Non-inventory items bought specifically to fill customer orders may possibly be returned, but on a case by case basis.
Customers who cancel orders after refurbishing has begun or after delivery where there are no equipment performance issues may be subject to a Restocking/Cancellation Fee of 20% or more and responsible for shipping costs for both the delivery and return.
Ongoing and Extended Support Options
American Instrument Exchange is able to provide additional repair and support services outside the warranty terms for most products that sell.
For biosafety cabinets, clean benches, chemical fume hoods, and other clean air products our team at AIE Laboratory Services can provide certifications, repairs, decontaminations, and other services for customers throughout New England, and guidance and limited technical assistance for any customers in the US and Canada for new or refurbished biosafety cabinets purchased from American Instrument Exchange.
For all other products, the repair service team at American Instrument Exchange can provide both field and depot repair evaluations. We can easily schedule and coordinate the pick-up and transportation of your malfunctioning equipment. By offering hourly rates lower than most OEM service providers and eliminating travel time for technicians, we help reduce repair costs. Furthermore, our lab depot repair service minimizes or eliminates scheduling delays. Our experienced service technicians are qualified to restore your equipment to factory specifications.
Yes, all equipment from American Instrument Exchange comes with a warranty. Used/reconditioned/refurbished equipment is tested to make sure it operates to the manufacturer's specifications and comes with a 90-day warranty (unless otherwise noted). New equipment comes with a warranty from the manufacturer.
How do you test and recondition the equipment?
Testing requirements vary across all the equipment categories we sell. Temperature controlled units are tested with NIST traceable probes and data loggers. Gaskets, external housing, glass, handles, controls and control screens are all thoroughly inspected for integrity and functionality. We test all equipment using the manufacturer's parameters and specifications to confirm that the unit operates properly.
How do products ship from American Instrument Exchange?
We can ship products both nationally and internationally using a well-established network of transporters. Smaller items will ship via UPS. Larger equipment will be palletized and shipped either LTL or air-ride, depending on the specific equipment and/or delivery requirements.
Return and order cancellation policy
American Instrument Exchange will accept the return of any product that is not working as represented and could not be replaced or repaired to the customer's satisfaction during the warranty period. Customers who cancel orders after refurbishing has begun will be subject to a cancellation and restocking fee of between 20% and 40%.
Are discounts available for educational or non-profit institutions, or for bulk purchases?
Yes – call or email us today with a list of equipment you're looking for and we can potentially put together a quote that includes a discount.
How does your price matching policy work?
We strive to keep our pricing competitive and reasonable. If you find comparable items for sale at a lower price from other vendors please send us a link and or quote for the item and we'll do our best to match or beat the price.
Can I see the equipment in person before committing to a purchase?
Customers are welcome to make an appointment to view equipment in our warehouse. Given our workload we may not be able to test or clean the equipment prior to your arrival if you have not committed to an order.
1023 Western Avenue is a working warehouse, not a showroom, and customers should dress appropriately and wear closed toe shoes.
Can I ship products that I purchased elsewhere to American Instrument for repair?
Yes – please see our repair services page for more information.
