Sartorius Secura SECURA225D-1S Dual-Range Semi-Micro Balance – New
The Sartorius Secura SECURA225D-1S Dual-Range Semi-Micro Balance combines 10 µg readability in its fine weighing range with a full 220 g capacity, giving laboratories the flexibility to perform extremely sensitive measurements while still accommodating larger samples and tare vessels.
Available brand new from American Instrument Exchange, the SECURA225D-1S provides a 120 g fine range with 0.01 mg readability and a 220 g full range with 0.1 mg readability. It also incorporates isoCAL automatic internal adjustment, Real-Time Level Support, automatic USP compliance monitoring, a color touchscreen, password protection, calibration history, SQmin functionality, and a manual draft shield designed for semi-micro weighing.
This combination makes the Secura particularly well suited for pharmaceutical, biotechnology, analytical, formulation, quality-control, and regulated laboratory environments where both weighing sensitivity and workflow control are important.
This balance is supplied new and includes the applicable Sartorius manufacturer warranty.
Key Features
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Dual-range 120 | 220 g maximum capacity
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0.01 | 0.1 mg readability
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10 µg fine-range resolution
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Repeatability of 0.03 | 0.07 mg
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Linearity of 0.1 | 0.2 mg
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Typical stabilization time of ≤4 | 1.5 seconds
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Typical optimal USP minimum sample weight of 8.2 mg
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isoCAL automatic internal adjustment
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Real-Time Level Support
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Automatic USP compliance monitoring
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SQmin functionality
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Color touchscreen display
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Manual ergonomic draft shield
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218 mm weighing-chamber height
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80 mm diameter weighing pan
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Calibration history
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GLP/GMP-compliant printout capability
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Password protection and configurable safety levels
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Sample identification capability
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Mini USB interface
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PC-direct data transfer
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Plug & Play connectivity to compatible Sartorius printers
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Brand new from American Instrument Exchange
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Sartorius manufacturer warranty included
Overview
The Sartorius Secura SECURA225D-1S is a high-performance semi-micro balance designed for laboratories that need substantially finer resolution than a conventional analytical balance while still requiring enough capacity for routine sample handling.
Its dual-range architecture provides 0.01 mg readability within the 120 g fine range and 0.1 mg readability up to the full 220 g capacity.
This gives users the ability to perform very small quantitative measurements without sacrificing the convenience of a larger overall weighing range.
The Secura platform also adds built-in quality and compliance safeguards designed to reduce common sources of weighing error.
These include automatic internal adjustment, real-time leveling guidance, automatic monitoring of weighing conditions, USP minimum-weight support, password protection, calibration history, and controlled data transfer.
Common Applications
The SECURA225D-1S is well suited for pharmaceutical formulation, analytical chemistry, standards preparation, quantitative sample preparation, biotechnology research, quality control, gravimetric analysis, density determination, component weighing, mixture preparation, statistical weighing, and other procedures requiring semi-micro sensitivity.
Pharmaceutical laboratories can use the Secura for active ingredients, reference standards, formulation work, stability testing, and quality-control procedures.
Biotechnology and research laboratories may use it for small compounds, reagents, powders, membranes, filters, and other samples where 0.1 mg analytical readability is insufficient.
Chemical laboratories can use the balance for high-precision standards preparation and quantitative analytical work.
Its built-in compliance features also make it particularly attractive for regulated environments where documentation and operator guidance are important.
Ideal Laboratory Types
The SECURA225D-1S is particularly well suited for pharmaceutical manufacturers, biotechnology companies, analytical laboratories, contract testing organizations, chemical laboratories, universities, research facilities, quality-control departments, and regulated laboratory environments.
It is especially useful where laboratories need occasional or frequent 10 µg measurements but still want the flexibility of a 220 g full-capacity balance.
The dual-range design can reduce the need to maintain separate semi-micro and conventional analytical balances for some workflows.
Dual-Range Semi-Micro Weighing Performance
The SECURA225D-1S provides two weighing ranges.
Within the 120 g fine range, the balance provides 0.01 mg readability.
Across the full 220 g range, readability is 0.1 mg.
This means the instrument functions as a semi-micro balance for smaller loads while still providing conventional analytical-balance resolution at higher loads.
Sartorius specifies repeatability of 0.03 mg in the fine range and 0.07 mg in the full range.
Linearity is specified at 0.1 mg and 0.2 mg respectively.
Typical stabilization time is ≤4 seconds in the fine range and approximately 1.5 seconds in the full range.
Understanding the Dual-Range Design
Dual-range balances provide finer resolution over a limited portion of the total weighing capacity.
For the SECURA225D-1S, that fine range extends to 120 g with 0.01 mg readability.
Above that range, the balance continues weighing up to 220 g with 0.1 mg readability.
This architecture is useful because many semi-micro applications involve relatively small net sample masses placed into heavier containers or weighing vessels.
Users should understand how tare operations and total applied load affect access to the fine range.
For critical methods, laboratories should establish weighing procedures that keep both container and sample within the portion of the range required for the desired readability.
Minimum Sample Weight & USP Applications
Sartorius specifies an optimal minimum sample weight according to USP and PhEur of approximately 8.2 mg for this model.
This is not the same as readability.
The balance may display 0.01 mg increments, but a valid minimum sample weight depends on repeatability performance and the acceptance criteria defined by the applicable weighing method.
For pharmaceutical and regulated laboratories, this distinction is important.
A sample that produces a visible reading is not automatically large enough to meet USP minimum-weight requirements.
The Secura platform helps users manage this through automatic USP compliance monitoring and SQmin functionality.
Automatic USP Compliance Monitoring
The Secura is designed to actively monitor whether weighing conditions are suitable for a reliable result.
Sartorius incorporates automatic USP compliance support into the platform to help laboratories reduce the risk of performing measurements below acceptable minimum-weight limits.
When used within an established quality system, this can help operators recognize when a sample is too small for the balance to meet the required uncertainty criteria.
This is especially valuable in pharmaceutical and quality-control laboratories where weighing errors can affect downstream analytical results.
SQmin Functionality
SQmin supports minimum-weight monitoring by allowing the balance to compare current sample mass with a defined minimum sample-weight threshold.
This provides an additional layer of operator guidance during routine weighing.
Rather than relying entirely on the technician to remember the method-specific minimum mass, the balance can help indicate whether the current sample is within the acceptable range.
Real-Time Level Support
Proper leveling is particularly important for semi-micro weighing.
The SECURA225D-1S incorporates Real-Time Level Support to continuously monitor balance leveling.
If the balance is not properly leveled, the system can alert the user before a questionable result is recorded or transferred.
This helps reduce one of the most common installation-related sources of weighing error.
It is especially useful in shared laboratories where equipment may be repositioned, cleaned, or moved between workstations.
isoCAL Automatic Internal Adjustment
The SECURA225D-1S includes Sartorius isoCAL automatic internal adjustment.
isoCAL uses an internal calibration mechanism to adjust the balance when defined time or temperature conditions indicate that adjustment is appropriate.
This helps maintain weighing performance as laboratory conditions change.
Automatic internal adjustment is particularly useful for semi-micro balances because very small environmental changes can have a greater effect on highly sensitive measurements.
External verification with appropriate certified weights may still be required according to laboratory quality procedures.
Controlling Drafts, Vibration & Static
At 0.01 mg readability, environmental control becomes a significant part of reliable weighing.
Air currents from HVAC systems, doors, fans, or operator movement can influence results.
Vibration from centrifuges, shakers, pumps, foot traffic, or unstable work surfaces can also affect stabilization.
Static charge can be particularly troublesome when weighing plastic vessels, powders, filters, or low-density materials.
The Secura includes a draft shield with coated glass components designed to help reduce electrostatic influences, but laboratories performing demanding semi-micro work should still control room conditions and sample handling carefully.
A stable balance table, appropriate environmental control, consistent sample temperature, and anti-static practices can significantly improve repeatability.
Manual Draft Shield
The SECURA225D-1S uses a manual draft shield designed for semi-micro weighing.
The enclosure protects the weighing pan from air movement while providing sufficient chamber height for common weighing vessels.
Sartorius specifies a weighing-chamber height of 218 mm.
The draft-shield design also supports ergonomic sample access while minimizing disturbances during sensitive measurements.
Color Touchscreen Interface
The Secura uses a color touchscreen to provide access to weighing applications, calibration records, system settings, and operator guidance.
The graphical interface makes it easier for technicians to navigate complex weighing functions without relying on abbreviated key sequences.
This can help simplify training and reduce operator error in multi-user laboratories.
Built-In Applications
The Secura platform includes integrated applications for both routine and advanced laboratory weighing.
Applications include weighing, density determination, percentage weighing, checkweighing, peak hold, counting, unstable-condition monitoring, animal weighing, mixture preparation, component weighing, statistics, and unit conversion.
These applications allow laboratories to perform common calculations directly through the balance rather than transferring every result to a separate computer or calculator.
Data Integrity & Controlled Data Transfer
The Secura continuously monitors weighing conditions and can prevent questionable results from being transferred to connected devices.
If the instrument detects unstable or uncertain conditions, data transfer to a computer or printer can be temporarily blocked.
This is particularly useful in regulated environments where an apparently valid number should not be exported if the balance itself has identified a weighing-condition problem.
The instrument also supports calibration history, sample identifiers, password protection, and configurable safety levels.
GLP/GMP Documentation
The SECURA225D-1S supports GLP/GMP-compliant printouts when used with compatible data-output equipment.
Documentation can include weighing and calibration information along with sample or batch identifiers.
For laboratories operating under controlled quality systems, this can simplify recordkeeping and help maintain traceability of weighing procedures.
Connectivity
The balance includes a Mini USB interface and supports PC-direct data transfer.
Results can be transferred directly into compatible Windows applications, reducing the need for manual transcription.
Programmable output intervals and multiple transfer formats are also supported.
Plug & Play connectivity is available for compatible Sartorius printers and peripherals.
Key Specifications
| Specification |
Sartorius Secura SECURA225D-1S |
| Balance Type |
Dual-Range Semi-Micro Balance |
| Maximum Capacity |
120 g Fine Range / 220 g Full Range |
| Readability |
0.01 mg / 0.1 mg |
| Repeatability |
0.03 mg / 0.07 mg |
| Linearity |
0.1 mg / 0.2 mg |
| Typical Stabilization Time |
≤4 s / 1.5 s |
| Optimal Minimum Sample Weight, USP/PhEur |
Approx. 8.2 mg |
| Adjustment |
Internal Automatic / isoCAL |
| Leveling |
Real-Time Level Support |
| Minimum-Weight Monitoring |
SQmin |
| USP Compliance Monitoring |
Yes |
| Draft Shield |
Manual |
| Weighing Chamber Height |
218 mm |
| Weighing Pan |
Ø80 mm |
| Display |
Color Touchscreen |
| Calibration History |
Yes |
| Sample Identification |
Yes |
| Password Protection |
Yes |
| Safety Levels |
Three Configurable Levels |
| Data Interface |
Mini USB |
| PC-Direct Transfer |
Yes |
| GLP/GMP Printout Support |
Yes |
| Underfloor Weighing |
No |
| Legal Verification |
Non-Verified |
| Dimensions |
218 mm W × 376 mm D × 316 mm H |
| Electrical |
100–240 V, 50–60 Hz |
| Condition |
New |
| Warranty |
Sartorius Manufacturer Warranty |
Secura Semi-Micro vs. Conventional Analytical Balance
A conventional analytical balance typically provides 0.1 mg readability.
The SECURA225D-1S provides ten times finer 0.01 mg readability within its 120 g fine range.
This makes the Secura better suited for smaller samples and procedures where conventional analytical-balance resolution does not provide sufficient measurement confidence.
The full 220 g range still provides 0.1 mg readability, giving laboratories the flexibility to perform conventional analytical work on the same instrument.
SECURA225D-1S vs. SECURA125-1S
The SECURA125-1S is a single-range semi-micro model with 120 g maximum capacity and 0.01 mg readability.
The SECURA225D-1S adds a second range, extending maximum capacity to 220 g while providing 0.1 mg readability above the fine range.
The SECURA125-1S is appropriate when all work remains below 120 g.
The SECURA225D-1S provides greater flexibility for laboratories that sometimes need larger tare vessels or heavier samples while still requiring semi-micro sensitivity for smaller measurements.
Dual-Range vs. Single-Range Semi-Micro Balances
A single-range semi-micro balance provides its finest readability throughout its entire weighing range.
A dual-range model such as the SECURA225D-1S provides its finest readability over a defined portion of the capacity and coarser readability over the remaining range.
The advantage of dual-range architecture is additional total capacity.
The tradeoff is that users must understand where the fine range applies.
Laboratories should choose between the two designs according to the mass of their typical containers, tare requirements, and the smallest samples they routinely weigh.
Choosing a Semi-Micro Balance for Regulated Laboratories
Semi-micro balances are often used in applications where documentation and process control matter as much as raw weighing sensitivity.
The SECURA225D-1S combines 10 µg readability with features intended to reduce operational risk.
Real-Time Level Support helps prevent measurements on an improperly leveled balance.
isoCAL helps maintain adjustment as environmental conditions change.
SQmin and USP monitoring help users recognize minimum-weight limitations.
Password protection and configurable safety levels help restrict unauthorized changes.
Calibration history and controlled data transfer improve traceability.
For pharmaceutical and quality-control laboratories, these features can simplify the development of a more controlled weighing process.
New Sartorius Secura Balances from American Instrument Exchange
This Sartorius Secura SECURA225D-1S is offered brand new through American Instrument Exchange.
It is not used or refurbished equipment.
The balance is supplied as new equipment and includes the applicable Sartorius manufacturer warranty.
For laboratories that require semi-micro sensitivity, dual-range flexibility, internal automatic adjustment, and integrated compliance safeguards, the Secura provides a sophisticated solution for both research and regulated quantitative weighing.
Shipping & Installation Considerations
A semi-micro balance should be installed with considerably more care than a routine precision balance.
The SECURA225D-1S should be placed on a rigid, stable, vibration-resistant balance table away from direct HVAC airflow, doors, fans, centrifuges, shakers, pumps, and heavy foot traffic.
The balance should be leveled after installation and allowed to acclimate to laboratory temperature before critical measurements begin.
Samples and weighing vessels should also be allowed to equilibrate when temperature differences could create convection currents inside the draft shield.
Static control may be necessary when working with plastics, powders, filters, or other materials prone to electrostatic charge.
For regulated work, laboratories should also establish routine external verification and minimum-weight procedures according to their quality system.
Related Laboratory Equipment
American Instrument Exchange maintains an extensive inventory of used, refurbished, and new laboratory balances, including analytical balances, semi-micro balances, microbalances, and precision balances for applications ranging from routine sample preparation to high-resolution quantitative analysis.
Labs developing complete analytical or sample-preparation workflows can also source centrifuges, water baths, incubators, laboratory refrigerators, laboratory freezers, and other laboratory equipment from American Instrument Exchange.
Sartorius Secura SECURA225D-1S FAQs
What is the maximum capacity of the SECURA225D-1S?
The balance provides a 120 g fine range and a maximum full-range capacity of 220 g.
What is the readability?
Readability is 0.01 mg within the fine range and 0.1 mg in the full range.
Is the SECURA225D-1S an analytical balance or a semi-micro balance?
Sartorius classifies the model as a semi-micro balance. Its 0.01 mg fine-range readability provides ten times finer resolution than a conventional 0.1 mg analytical balance.
What is the repeatability?
Sartorius specifies repeatability of 0.03 mg in the fine range and 0.07 mg in the full range.
What is the linearity?
Linearity is specified at 0.1 mg in the fine range and 0.2 mg in the full range.
What is the minimum sample weight?
Sartorius specifies an optimal USP and PhEur minimum sample weight of approximately 8.2 mg.
Does the Secura include internal calibration?
Yes. The SECURA225D-1S uses Sartorius isoCAL automatic internal adjustment.
What is Real-Time Level Support?
Real-Time Level Support monitors whether the balance is correctly leveled and provides guidance when adjustment is required.
What is SQmin?
SQmin allows the balance to monitor whether a sample meets a defined minimum-weight requirement.
Does the balance support USP compliance?
Yes. The Secura includes automatic USP compliance monitoring designed to help laboratories recognize weighing conditions that may not meet minimum-weight requirements.
Does the SECURA225D-1S have a draft shield?
Yes. It has a manual draft shield with a weighing-chamber height of approximately 218 mm.
What size is the weighing pan?
The weighing pan is approximately 80 mm in diameter.
Does the Secura have a touchscreen?
Yes. It uses a color touchscreen interface.
Can results be transferred to a computer?
Yes. The balance includes Mini USB connectivity and supports PC-direct data transfer to compatible Windows applications.
Is this model legal for trade?
The SECURA225D-1S described here is the non-verified version.
What is the difference between SECURA225D-1S and SECURA125-1S?
The SECURA125-1S provides 120 g maximum capacity with 0.01 mg readability. The SECURA225D-1S adds a 220 g full range with 0.1 mg readability while retaining a 120 g fine range at 0.01 mg.
Is this Sartorius Secura new or refurbished?
This SECURA225D-1S is offered brand new through American Instrument Exchange and includes the applicable Sartorius manufacturer warranty.
Why choose the Sartorius Secura SECURA225D-1S?
The SECURA225D-1S combines 10 µg fine-range readability, 220 g total capacity, isoCAL automatic adjustment, Real-Time Level Support, USP compliance monitoring, SQmin, a color touchscreen, calibration history, controlled data transfer, and integrated compliance features in a dual-range semi-micro balance designed for demanding analytical and regulated laboratory workflows.
